Exhibit 4.1
THIS WARRANT AND THE SHARES OF COMMON STOCK
PURCHASABLE HEREUNDER HAVE NOT BEEN REGISTERED UNDER THE SECURITIES
ACT OF 1933 AND MAY NOT BE SOLD OR OFFERED FOR SALE UNLESS
REGISTERED UNDER SAID ACT AND ANY APPLICABLE STATE SECURITIES LAWS
OR UNLESS AN EXEMPTION FROM SUCH REGISTRATION IS
AVAILABLE.
Dated: October 23, 2008
WARRANT
To Purchase 65,000 Shares of Common
Stock
of ADVANCED LIFE SCIENCES HOLDINGS,
INC.
Expiring October 23, 2013
THIS TO CERTIFY THAT
, for value received, THE
LEADERS GROUP, INC., an Illinois corporation or any registered
assigns (“ Holder ”) is entitled to purchase
from ADVANCED LIFE SCIENCES HOLDINGS, INC. , a Delaware
corporation (the “ Company ”), at any time or
from time to time after 9:00 a.m., Chicago time, on the date
hereof and prior to 5:00 p.m., Chicago time, on
October 23, 2013, at the place where the Warrant Agency is
located, at the Exercise Price, the number of shares of Common
Stock, par value $.01 per share, of the Company (the “
Common Stock ”) shown above, subject to adjustment as
provided in Articles IV and V hereof, and upon the terms
and conditions hereinafter provided, and is entitled also to
exercise the other appurtenant rights, powers and privileges
hereinafter described.
This Warrant entitles the holder
initially to purchase up to an aggregate of 65,000 shares of Common
Stock. This Warrant has been issued by the Company pursuant
to the Amended and Restated Business Loan Agreement dated as of
October 23, 2008 (as amended from time to time, the “
Loan Agreement ”) between the Company and Holder, in
consideration of a loan to the Company by the Holder. The
Holder is entitled to certain benefits as set forth therein.
The Company shall keep a copy of the Loan Agreement, and any
amendments thereto, at the Warrant Agency, and shall furnish,
without charge, copies thereof to the Holder upon
request.
Certain terms used in this Warrant
are defined in Article VI.
ARTICLE I
EXERCISE OF WARRANTS
I.1.
Method of Exercise
. To exercise this
Warrant in whole or in part, the Holder shall deliver on any
Business Day to the Company at the Warrant Agency (a) this
Warrant, (b) a written notice of the Holder’s election
to exercise this Warrant, which notice shall specify the number of
shares of Common Stock to be purchased (which shall be a whole
number of shares if for less than all the shares then issuable
hereunder), the denominations of the share certificate
or
certificates desired and the
name or names in which such certificates are to be registered, and
(c) payment of the Exercise Price with respect to such
shares. Such payment may be made by cash, certified or bank
cashier’s check or wire transfer in an amount equal to the
product of (i) the Exercise Price times (ii) the number
of Warrant Shares as to which this Warrant is being
exercised.
The Company shall, as promptly as
practicable and in any event within seven days after receipt of
such notice and payment, execute and deliver or cause to be
executed and delivered, in accordance with such notice, a
certificate or certificates representing the aggregate number of
shares of Common Stock specified in said notice together with cash
in lieu of any fractions of a share as provided in
Section 1.3. The share certificate or certificates so
delivered shall be in such denominations as may be specified in
such notice, and shall be issued in the name of the Holder or such
other name or names as shall be designated in such notice.
This Warrant shall be deemed to have been exercised and such
certificate or certificates shall be deemed to have been issued,
and such Holder or any other Person so designated to be named
therein shall be deemed for all purposes to have become a holder of
record of shares, as of the date the aforementioned notice and
payment is received by the Company. If this Warrant shall
have been exercised only in part, the Company shall, at the time of
delivery of such certificate or certificates, deliver to the Holder
a new Warrant evidencing the right to purchase the remaining shares
of Common Stock called for by this Warrant, which new Warrant shall
in all other respects be identical with this Warrant, or, at the
request of the Holder, appropriate notation may be made on this
Warrant which shall then be returned to the Holder. The
Company shall pay all expenses, taxes and other charges payable in
connection with the preparation, issuance and delivery of share
certificates and new Warrants, except that, if share certificates
or new Warrants shall be registered in a name or names other than
the name of the Holder, funds sufficient to pay all transfer taxes
payable as a result of such transfer shall be paid by the Holder at
the time of delivery of the aforementioned notice of exercise or
promptly upon receipt of a written request of the Company for
payment.
I.2.
Shares to be Fully Paid and
Nonassessable .
All shares
of Common Stock issued upon the exercise of this Warrant shall be
validly issued, fully paid and nonassessable.
I.3.
No Fractional Shares Required to
be Issued .
The
Company shall not be required to issue fractions of shares of
Common Stock upon exercise of this Warrant. If any fraction
of a share would, but for this Section, be issuable upon final
exercise of this Warrant, in lieu of such fractional share, the
Company shall pay to the Holder in cash an amount equal to the same
fraction of the Fair Market Value of the Company per share of
outstanding Common Stock on the Business Day immediately prior to
the date of such exercise.
I.4.
Legend . Each certificate for
shares of Common Stock issued upon exercise of this Warrant, unless
at the time of exercise such shares are registered under the
Securities Act, shall bear the following legend:
“This security has not been
registered under the Securities Act of 1933 and may not be sold or
offered for sale unless registered under said Act and any
applicable state securities laws or unless an exemption from such
registration is available.”
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Any certificate issued at any time
in exchange or substitution for any certificate bearing such legend
(except a new certificate issued upon completion of a public
offering pursuant to a registration statement under the Securities
Act) shall also bear such legend unless, in the opinion of counsel
selected by the Holder of such certificate (who may be an employee
of such holder) and reasonably acceptable to the Company, the
securities represented thereby need no longer be subject to
restrictions on resale under the Securities Act.
I.5.
Reservation
. The Company has duly
reserved, and will keep available for issuance upon exercise of the
Warrants, the total number of Warrant Shares deliverable from time
to time upon exercise of all Warrants from time to time
outstanding. The Company will not take any actions during the
term of this Warrant that would result in any adjustment of the
number of shares of Common Stock issuable upon the exercise of the
Warrant if (i) the total number of shares of Common Stock
issuable after such action upon exercise of this Warrant,
(ii) all shares of Common Stock issued and outstanding and
(iii) all shares then issuable (y) upon the exercise of
all Options and (z) upon the conversion or exchange of all
Convertible Securities, would exceed the total number of shares of
Common Stock then authorized for issuance by the Company. The
Company will not change the Common Stock from par value $.01 per
share to any higher par value which exceeds the Exercise Price then
in effect, and will reduce the par value of the Common Stock upon
any event described in Article IV that provides for an
increase in the number of shares of Common Stock subject to
purchase upon exercise of this Warrant, in inverse proportion to
and effective at the same time as such number of shares is
increased. As of the date hereof, the Company had outstanding
(i) 40,805,932 shares of Common Stock, (ii) [11,347,648]
Options to purchase Common Stock, and no other shares of capital
stock or any securities convertible into or exchangeable for shares
of capital stock or any rights, options or warrants to purchase any
shares of capital stock or any securities convertible into or
exchangeable for shares of capital stock. Neither the
issuance of this Warrant nor the issuance of Warrant Shares upon
exercise of this Warrant violates or conflicts with the
Company’s certificate of incorporation or bylaws or any
agreement to which the Company is a party.
ARTICLE II
WARRANT AGENCY;
TRANSFER, EXCHANGE AND REPLACEMENT OF
WARRANTS
II.1.
Warrant Agency
. As long as any
Warrant remains outstanding, the Company shall perform the
obligations of and be the warrant agency with respect to the
Warrants (the “ Warrant
Agency ”) at its address set
forth in the Loan Agreement or at such other address as the Company
shall specify by notice to the Holder.
II.2.
Ownership of Warrant
. The Company may deem
and treat the person in whose name this Warrant is registered as
the holder and owner hereof (notwithstanding any notations of
ownership or writing hereon made by any person other than the
Company) for all purposes and shall not be affected by any notice
to the contrary, until due presentment of this Warrant for
registration of transfer as provided in this
Article II.
II.3.
Transfer of Warrant
. The Company agrees to
maintain at the Warrant Agency books for the registration of
transfers of the Warrants, and transfer of this Warrant and all
rights
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hereunder shall be
registered, in whole or in part, on such books, upon surrender of
this Warrant at the Warrant Agency, together with a written
assignment of this Warrant duly executed by the Holder or its duly
authorized agent or attorney, with (if the Holder is a natural
person) signatures guaranteed by a bank or trust company or a
registered broker or dealer, and funds sufficient to pay any
transfer taxes payable upon such transfer. Upon surrender
and, if required, such payment, the Company shall execute and
deliver a new Warrant or Warrants in the name of the assignee or
assignees and in the denominations specified in the instrument of
assignment (which shall be whole numbers of shares only) and shall
issue to the assignor a new Warrant evidencing the portion of this
Warrant not so assigned, and this Warrant shall promptly be
canceled.
II.4.
Division or Combination of
Warrants .
This
Warrant may be divided or combined with other Warrants upon
presentment hereof and of any Warrant or Warrants with which this
Warrant is to be combined at the Warrant Agency, together with a
written notice specifying the names and denominations (which shall
be whole numbers of shares only) in which the new Warrant or
Warrants are to be issued, signed by the holders hereof and thereof
or their respective duly authorized agents or attorneys.
Subject to compliance with Section 2.3 as to any transfer or
assignment which may be involved in the division or combination,
the Company shall execute and deliver a new Warrant or Warrants in
exchange for the Warrant or Warrants to be divided or combined in
accordance with such notice.
II.5.
Loss, Theft, Destruction of
Warrant Certificates . Upon receipt of
evidence satisfactory to the Company of the ownership of and the
loss, theft, destruction or mutilation of any Warrant and, in the
case of any such loss, theft or destruction, upon receipt of
indemnity or security satisfactory to the Company (it being
understood and agreed that if the holder of such Warrant is Leaders
Bank, then a written agreement of indemnity given by Leaders Bank
alone shall be satisfactory to the Company and no further security
shall be required) or, in the case of any such mutilation, upon
surrender and cancellation of such Warrant, the Company will make
and deliver, in lieu of such lost, stolen, destroyed or mutilated
Warrant, a new Warrant of like tenor and representing the right to
purchase the same aggregate number of shares of Common
Stock.
II.6.
Expenses of Delivery of
Warrants .
The
Company shall pay all expenses, taxes (other than transfer taxes)
and other charges payable in connection with the preparation,
issuance and delivery of Warrants hereunder.
ARTICLE III
CERTAIN RIGHTS
III.1.
Determination of Fair Market
Value .
Each
determination of Fair Market Value hereunder shall be made in good
faith by the Company. Upon each determination of Fair Market
Value by the Company hereunder, the Company shall promptly give
notice thereof to the Holder, setting forth in reasonable detail
the calculation of such Fair Market Value and the method and basis
of determination thereof (the “ Company Determination ”).
III.2.
Financial Statements and Other
Information .
Promptly
upon transmission thereof, to the extent required under the Loan
Agreement, the Company will deliver to the
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Holder copies of any and all
financial statements, proxy statements, notices and other reports
as it may send to its public stockholders and copies of all
registration statements and all reports which it files with the
Securities and Exchange Commission (or any governmental body or
agency succeeding to its functions).
ARTICLE IV
ANTIDILUTION PROVISIONS
IV.1.
General . The Exercise Price
and the number of shares of Common Stock (or other securities or
property) issuable upon exercise of this Warrant shall be subject
to adjustment from time to time upon the occurrence of certain
events as provided in this Article IV; provided that
notwithstanding anything to the contrary herein, the Exercise Price
shall not be less than the par value of the Common Stock, as such
par value is reduced from time to time in accordance with
Section 1.5.
IV.2.
Common Stock
Reorganization .
If the
Company shall subdivide its outstanding shares of Common Stock (or
any class thereof) into a greater number of shares or consolidate
its outstanding shares of Common Stock (or any class thereof) into
a smaller number of shares (any such event being called a
“ Common Stock
Reorganization ”), then (a) the
Exercise Price shall be adjusted, effective immediately after the
effective date of such Common Stock Reorganization, to a price
determined by multiplying the Exercise Price in effect immediately
prior to such effective date by a fraction, the numerator of which
shall be the number of shares of Common Stock outstanding on such
effective date before giving effect to such Common Stock
Reorganization and the denominator of which shall be the number of
shares of Common Stock outstanding after giving effect to such
Common Stock Reorganization, and (b) the number of shares of
Common Stock subject to purchase upon exercise of this Warrant
shall be adjusted, effective at such time, to a number determined
by multiplying the number of shares of Common Stock subject to
purchase immediately before such Common Stock Reorganization by a
fraction, the numerator of which shall be the number of shares of
Common Stock outstanding after giving effect to such Common Stock
Reorganization and the denominator of which shall be the number of
shares of Common Stock outstanding immediately before such Common
Stock Reorganization.
IV.3.
Common Stock
Distribution .
(a) If the Company shall issue, sell or otherwise distribute
any shares of Common Stock, other than pursuant to this Agreement
or a Common Stock Reorganization (which is governed by
Section 4.2 hereof) (any such event, including any event
described in paragraphs (b) and (c) below,
being herein called a “ Common Stock Distribution ”), for a consideration
per share less than the Fair Market Value of the Company per share
of outstanding Common Stock on a Fully Diluted Basis on the date of
such Common Stock Distribution (before giving effect to such Common
Stock Distribution), then, effective upon such Common Stock
Distribution, the Exercise Price shall be reduced, if such
consideration per share shall be less than such Fair Market Value
per share, to the lowest of the prices (calculated to the nearest
one thousandth of one cent) determined as provided in
clauses (i), (ii) and (iii) below:
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(i)
if the Company
shall receive any consideration for the Common Stock issued, sold
or distributed, in such Common Stock Distribution, the
consideration per share of Common Stock received by the Company
upon such issue, sale or distribution;
(ii)
by dividing
(A) an amount equal to the sum of (1) the number of
shares of Common Stock outstanding immediately prior to such Common
Stock Distribution multiplied by the then existing Exercise Price,
plus (2) the consideration, if any, received by the
Company upon such Common Stock Distribution by (B) the total
number of shares of Common Stock outstanding immediately after such
Common Stock Distribution; and
(iii)
by multiplying
the Exercise Price in effect immediately prior to such Common Stock
Distribution by a fraction, the numerator of which shall be the sum
of (A) the number of shares of Common Stock outstanding
immediately prior to such Common Stock Distribution multiplied by
such Fair Market Value per share on the date of such Common Stock
Distribution, plus (B) the consideration, if any,
received by the Company upon such Common Stock Distribution, and
the denominator of which shall be the product of (1) the total
number of shares of Common Stock outstanding immediately after such
Common Stock Distribution multiplied by (2) such Fair Market
Value per share on the date of such Common Stock
Distribution.
If any Common Stock Distribution
shall require an adjustment to the Exercise Price pursuant to the
foregoing provisions of this paragraph (a), including by
operation of paragraph (b) or (c) below, then,
effective at the time such adjustment is made, the number of shares
of Common Stock subject to purchase upon exercise of this Warrant
shall be increased to a number determined by multiplying the number
of shares of Common Stock subject to purchase immediately before
such Common Stock Distribution by a fraction, the numerator of
which shall be the number of shares of Common Stock outstanding
immediately after giving effect to such Common Stock Distribution
and the denominator of which shall be the sum of the number of
shares outstanding immediately before giving effect to such Common
Stock Distribution (both calculated on a Fully Diluted Basis)
plus the number of shares of Common Stock which the
aggregate consideration received by the Company with respect to
such Common Stock Distribution would purchase at the Fair Market
Value of the Company per share of outstanding Common Stock on a
Fully Diluted Basis on the date of such Common Stock Distribution
(before giving effect to such Common Stock Distribution). In
computing adjustments under this paragraph, fractional interests in
Common Stock shall be taken into account to the nearest
one-thousandth of a share.
The provisions of this
paragraph (a), including by operation of
paragraph (b) or (c) below, shall not operate
to increase the Exercise Price or reduce the number of shares of
Common Stock subject to purchase upon exercise of this
Warrant.
(b)
If the Company
shall issue, sell, distribute or otherwise grant in any manner
(including by assumption) any rights to subs
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