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POLYMEDIX, INC. SERIES B WARRANT TO PURCHASE CAPITAL STOCK

Warrant Agreement

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This Warrant Agreement involves

POLYMEDIX, INC

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Title: POLYMEDIX, INC. SERIES B WARRANT TO PURCHASE CAPITAL STOCK
Governing Law: Delaware     Date: 9/24/2008
Industry: Biotechnology and Drugs     Sector: Healthcare

POLYMEDIX, INC. SERIES B WARRANT TO PURCHASE CAPITAL STOCK, Parties: polymedix  inc
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Exhibit 4.2

POLYMEDIX, INC.
SERIES B WARRANT TO PURCHASE CAPITAL STOCK
To Purchase [
                     ] Shares of Preferred Stock or [                      ] Shares of Common Stock

Date of Issuance:                      , 2008

VOID AFTER [                                                                      ], 2013

     THIS CERTIFIES THAT, for value received, [                      ], or permitted registered assigns (the “ Holder ”), is entitled to subscribe for and purchase at the Exercise Price (defined below) from PolyMedix, Inc., a Delaware corporation (the “ Company ”), either (a) up to [               ] shares (“ Preferred Warrant Shares ”) of Series 2008 Convertible Preferred Stock of the Company, par value $0.001 per share (“ Preferred Stock ”), or (b) if, at the time this Warrant is exercised (in whole or in part) the Preferred Stock has been converted into shares of the common stock of the Company, par value $0.001 per share (the “ Common Stock ”), up to [               ] shares of Common Stock (“ Common Warrant Shares ”). This warrant is one of a series of warrants issued by the Company as of the date hereof (individually a “ Warrant ”, collectively, “ Company Warrants ”) pursuant to a series of securities purchase agreements dated as of                      , 2008, each between the Company and the investor named therein (the “ Securities Purchase Agreement ”).

     1.  DEFINITIONS . Capitalized terms used herein but not otherwise defined herein shall have their respective meanings as set forth in the Securities Purchase Agreement. As used herein, the following terms shall have the following respective meanings:

          (a) “ Conversion Date ” shall mean the date of effectiveness of the Amendment to the Company’s Charter.

          (b) “ Exercise Period ” shall mean the period commencing with the date that is the earlier of (i) six months after the Closing Date or (ii) the Conversion Date, unless sooner terminated as a result of a Fundamental Transaction pursuant to Section 7 below, and ending on the fifth anniversary of the Closing Date.

          (c) “ Exercise Price ” shall mean $10.00 per share with respect to the Preferred Warrant Shares if this Warrant is exercisable for Preferred Warrant Shares and $1.00 per share with respect to the Common Warrant Shares if this Warrant is exercisable for Common Warrant Shares, in either case subject to adjustment pursuant to Section 5 below.

          (d) “ Trading Day ” shall mean (i) any day on which the Common Stock is listed or quoted on its primary trading market, (ii) if the Common Stock is not then listed or quoted and traded on any eligible market (meaning any of the New York Stock Exchange, American Stock Exchange (“ AMEX ”) or The NASDAQ Global Market), then a day on which trading occurs on the OTC Bulletin Board (or any successor thereto), or (iii) if trading does not occur on the OTC Bulletin Board (or any successor thereto), any business day.

 


 

          (e) “ Warrant Shares ” shall mean the shares of Common Stock or Preferred Stock, as applicable, issuable upon exercise of this Warrant.

     2.  EXERCISE OF WARRANT .

          2.1 TYPE OF WARRANT SHARES . This Warrant shall be exercisable only for Preferred Warrant Shares unless and until the Preferred Stock is converted into Common Stock pursuant to the Designations, after which this Warrant shall be exercisable only for Common Warrant Shares.

          2.2 EXERCISE MECHANICS . The rights represented by this Warrant may, subject to Section 6 below, be exercised in whole or in part at any time during the Exercise Period, by delivery of the following to the Company at its address set forth on the signature page hereto (or at such other address as it may designate by notice in writing to the Holder):

          (a) An executed Notice of Exercise in the form attached hereto; and

          (b) Payment of the Exercise Price either in cash or by check or, if applicable, in accordance with Section 4, (subject to the limitations in Section 2.3 below.

     Execution and delivery of the Notice of Exercise shall have the same effect as cancellation of the original Warrant and issuance of a new Warrant evidencing the right to purchase the remaining number of Warrant Shares, if any. If requested by the Company, Holder agrees to provide this Warrant, or an affidavit of lost security, to the Company within a reasonable period after the delivery of the Notice of Exercise.

     Certificates for shares purchased hereunder shall be transmitted by the transfer agent of the Company to the Holder by crediting the account of the Holder’s prime broker with the Depository Trust Company through its Deposits and Withdrawal at Custodian (DWAC) system if the Company is a participant in such system, and otherwise by physical delivery to the address specified by the Holder in the Notice of Exercise within three business days from the delivery to the Company of the Notice of Exercise, surrender of this Warrant and payment of the aggregate Exercise Price as set forth above. This Warrant shall be deemed to have been exercised on the date the Exercise Price is received by the Company. The Warrant Shares shall be deemed to have been issued, and Holder or any other person so designated to be named therein shall be deemed to have become a holder of record of such shares for all purposes, as of the date this Warrant has been exercised by payment to the Company of the Exercise Price. In the event that this Warrant is exercisable for Common Warrant Shares, if by the close of the third Trading Day after delivery of a Notice of Exercise, the Company fails to deliver to the Holder a certificate representing the required number of Common Warrant Shares in the manner required pursuant to this Section 2 , and such failure to deliver the Common Warrant Shares is caused by the Company’s failure to use commercially reasonable efforts to comply with this Section 2 and/or the covenants in Section 3 herein, and if after such third Trading Day and prior to the receipt of such Common Warrant Shares, the Holder purchases (in an open market transaction or otherwise) shares of Common Stock to deliver in satisfaction of a sale by the Holder of the Common Warrant Shares which the Holder anticipated receiving upon such exercise (a “ Buy-In ”), then the Company shall, within three Trading Days after the Holder’s request and in the

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Holder’s sole discretion, either (i) pay in cash to the Holder an amount equal to the Holder’s total purchase price (including brokerage commissions, if any) for the shares of Common Stock so purchased (the “ Buy-In Price ”), at which point the Company’s obligation to deliver such certificate (and to issue such Common Warrant Shares) shall terminate or (ii) promptly honor its obligation to deliver to the Holder a certificate or certificates representing such Common Warrant Shares and pay cash to the Holder in an amount equal to the excess (if any) of the Buy-In Price over the product of (A) such number of Common Warrant Shares, times (B) the closing bid price on the date of the event giving rise to the Company’s obligation to deliver such certificate.

     The person in whose name any Warrant Shares are to be issued upon exercise of this Warrant shall be deemed to have become the holder of record of such shares on the date on which this Warrant was surrendered and payment of the Exercise Price was made, irrespective of the date of delivery of such certificate or certificates, except that, if the date of such surrender and payment is a date when the stock transfer books of the Company are closed, such person shall be deemed to have become the holder of such shares at the close of business on the next succeeding date on which the stock transfer books are open.

     To the extent permitted by law, the Company’s obligations to issue and deliver Warrant Shares in accordance with the terms hereof are absolute and unconditional, irrespective of any action or inaction by the Holder to enforce the same, any waiver or consent with respect to any provision hereof, the recovery of any judgment against any person or entity or any action to enforce the same, or any setoff, counterclaim, recoupment, limitation or termination, or any breach or alleged breach by the Holder or any other person or entity of any obligation to the Company or any violation or alleged violation of law by the Holder or any other person or entity, and irrespective of any other circumstance which might otherwise limit such obligation of the Company to the Holder in connection with the issuance of Warrant Shares. Nothing herein shall limit a Holder’s right to pursue any other remedies available to it hereunder, at law or in equity including, without limitation, a decree of specific performance and/or injunctive relief with respect to the Company’s failure to timely deliver certificates representing the Warrant Shares upon exercise of this Warrant as required pursuant to the terms hereof.

          2.3 ISSUANCE OF NEW WARRANTS . Upon any partial exercise of this Warrant, the Company, at its expense, will forthwith and, in any event within five business days, issue and deliver to the Holder a new warrant or warrants of like tenor, registered in the name of the Holder, exercisable, in the aggregate, for the balance of the number of the Warrant Shares remaining available for purchase under this Warrant.

          2.4 EXERCISE LIMITATIONS; HOLDER’S RESTRICTIONS . A Holder shall not have the right to exercise any portion of this Warrant, pursuant to Section 2 or otherwise, to the extent that after giving effect to such issuance after exercise, such Holder (together with such Holder’s affiliates), as set forth on the applicable Notice of Exercise, would beneficially own in excess of 9.99% of the number of shares of the Common Stock outstanding immediately after giving effect to such issuance, unless the Holder of this Warrant elects to waive the provisions of this Section 2.4 upon not less than 61 days’ prior notice to the Company. For purposes of the foregoing sentence, the number of shares of Common Stock beneficially owned by such Holder and its affiliates shall include the number of shares of Common Stock

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issuable upon exercise of this Warrant if this Warrant is exercisable for Common Warrant Shares with respect to which the determination of such sentence is being made, but shall exclude the number of shares of Common Stock which would be issuable upon (a) exercise of the remaining, non-exercised portion of this Warrant beneficially owned by such Holder or any of its affiliates and (b) exercise or conversion of the unexercised or non-converted portion of any other securities of the Company (including, without limitation, any other shares of Common Stock or Warrants) subject to a limitation on conversion or exercise analogous to the limitation contained herein beneficially owned by such Holder or any of its affiliates. Except as set forth in the preceding sentence, for purposes of this Section 2.4 , beneficial ownership shall be calculated in accordance with Section 13(d) of the Exchange Act, it being acknowledged by a Holder that the Company is not representing to such Holder that such calculation is in compliance with Section 13(d) of the Exchange Act and such Holder is solely responsible for any schedules required to be filed in accordance therewith. To the extent that the limitation contained in this Section 2.4 applies, the determination of whether this Warrant is exercisable (in relation to other securities owned by such Holder) and of which a portion of this Warrant is exercisable shall be in the sole discretion of a Holder, and the submission of a Notice of Exercise shall be deemed to be each Holder’s determination of whether this Warrant is exercisable (in relation to other securities owned by such Holder) and of which portion of this Warrant is exercisable, in each case subject to such aggregate percentage limitation, and the Company shall have no obligation to verify or confirm the accuracy of such determination. For purposes of this Section 2.4 , in determining the number of outstanding shares of Common Stock, a Holder may rely on the number of outstanding shares of Common Stock as reflected in (x) the Company’s most recent Form 10-Q or Form 10-K, as the case may be, (y) a more recent public announcement by the Company or (z) any other notice by the Company or the Company’s transfer agent setting forth the number of shares of Common Stock outstanding. Upon the written or oral request of a Holder, the Company shall within two Trading Days confirm orally and in writing to such Holder the number of shares of Common Stock then outstanding. In any case, the number of outstanding shares of Common Stock shall be determined after giving effect to the conversion or exercise of securities of the Company, including this Warrant, by such Holder or its affiliates since the date as of which such number of outstanding shares of Common Stock was reported.

     3.  COVENANTS OF THE COMPANY .

          3.1 DUE AUTHORIZATION . The Company covenants and agrees that all Warrant Shares that may be issued upon the exercise of the rights represented by this Warrant will, upon issuance, be validly issued and outstanding, fully paid and nonassessable, and free from all taxes, liens and charges with respect to the issuance thereof.

          3.2 FILING OF CERTIFICATE OF AMENDMENT . Subject to the Stockholders Approval, the Company shall file the Certificate of Amendment pursuant to Section 4.5(b) of the Securities Purchase Agreement.

          3.3 AVAILABLE SHARES . The Company covenants and agrees that the Company will at all times during the Exercise Period, have authorized and reserved, free from preemptive rights, a sufficient number of shares of Preferred Stock or Common Stock, as applicable, to provide for the exercise of the rights represented by this Warrant. During the Exercise Period, the number of authorized but unissued shares of Preferred Stock or Common

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Stock, as applicable, shall not be sufficient to permit exercise of this Warrant into the applicable Warrant Shares, the Company will take such corporate action as may, in the opinion of its counsel, be necessary to increase its authorized but unissued shares of Preferred Stock or Common Stock, as applicable, to suc


 
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