Exhibit 10.1
Termination Agreement
to
Master Clinical Services Agreement
and
Work Order No. 1 and 2
(also referred to as Work Order A and B)
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29
May 2009 (the “Effective Date”)
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Neurobiological
Technologies, Inc., 2000 Powell Street, Suite 800, Emeryville,
California 94608 USA (“Sponsor”)
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ICON Clinical
Research Limited of South County Business Park, Leopardstown,
Dublin 18, Ireland (“Service Provider”).
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A.
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The
parties entered into a Master Clinical Services Agreement for
Services dated 16 th January 2007 (the
“Agreement”).
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B.
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Thereafter the parties entered into
a Work Order No. 1, dated the 16 th of May 2007, concerning a
study known as “Study of Acute Viprinex
TM
for Emergency Stroke: A
Randomized, Double-Blind, Placebo-Controlled Study of Ancrod
(Viprinex TM ) in Subjects Beginning Treatment
within 6 Hours of the Onset of Acute, Ischemic Stroke
(ASP-1)”, Protocol NTI-ASP-0502” (the “Work Order
No. 1”), as amended by Change Order No. 1 dated the
9 th November 2007 (“Study
No. 1”).
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C.
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Thereafter the parties entered into
a Work Order No. 2, dated the 16 th of May 2007, concerning a
study known as “ASP-II (Ancrod in Stroke program – II):
A Randomized, Double-Blind, Placebo-Controlled Study of Ancrod
(Viprinex TM ) for Emergency Stroke: A
Randomized, Double-Blind, Placebo-Controlled Study of Ancrod
(Viprinex TM ) in Subjects Beginning Treatment
within 6 Hours of the Onset of Acute, Ischemic Stroke”,
Protocol NTI-ASP-0503” (the “Work Order
No. 2”) as amended by Change Order No. 1 dated the
9 th November 2007 (“Study
No. 2”).
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D.
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The
parties also now wish to terminate the Agreement and Work Order
No.1 and Work No. 2 (collectively the “Work
Orders”), as well as any and all Change Orders to the Work
Orders, subject to the terms and conditions set forth in this
Termination Agreement
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In consideration of the premises
and mutual promises and covenants herein contained, the adequacy of
which is acknowledged by each of the parties, IT IS AGREED BY
THE PARTIES AS FOLLOWS:
1.
Termination of Agreement and Work
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