Supply Agreement

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This Supply Agreement involves

NeoRx Corporation

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Title: Supply Agreement
Date: 3/2/2005
Industry: Biotechnology and Drugs Sector: Healthcare

Supply Agreement, Parties: neorx corporation

Exhibit 10.1

[On NeoRx Corporation Letterhead]

November 4, 2004

Mr. Ken Brooks

Associate Director

University of Missouri Research Reactor

1513 Research Park Drive

Columbia, MO 65211

RE: March 1, 2004 Supply Agreement

NeoRx Corporation — MURR

Dear Ken,

We are pleased to inform you and the University that pursuant to paragraph 10.1(b) of our Supply Agreement, NeoRx wishes to exercise our option to extend the term of such agreement another year, which would effectively extend t

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