AMENDMENT TO SUPPLY AGREEMENT

Supply Agreement

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This Supply Agreement involves

VASCULAR SOLUTIONS INC

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Title: AMENDMENT TO SUPPLY AGREEMENT
Date: 2/2/2007
Industry: HTHEQP Sector: HEALTH

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EXHIBIT 10.12

AMENDMENT TO THE

“SUPPLY AGREEMENT”

This Amendment to the Supply Agreement (the “Amendment”) is made as of this 15th day of December, 2006 by and between Vascular Solutions, Inc., having an office at 6464 Sycamore Court, Minneapolis, MN 55369 (“Buyer”) and SAFC, an operating division of Sigma-Aldrich Inc., having an office at 3050 Spruce St., St. Louis, MO 63103, USA (“Seller”) (collectively the “Parties”).

RECITALS

WHEREAS, Buyer and Seller are parties to the Supply Agreement dated October 18, 2004 relating to the commercial supply of thrombin solution from bovine plasma (“Agreement”);

WHEREAS, the Parties now wish to amend certain terms of the Agreement;

NOW THEREFORE, in consideration of the mutual covenants and agreements set forth herein, and for other good and valuable consideration the sufficiency of which is ackn