Exhibit 4.53
Confidential treatment has been
requested for certain portions of this exhibit. The copy filed
herewith omits the information subject to the confidential
treatment request. Omissions are designated as “ *****
”. A complete version of this exhibit has been filed
separately with the Commission pursuant to an application for
confidential treatment under Rule 24b-2 promulgated under the
Securities Exchange Act of 1934, as amended.
Modification 0001
ACAMBIS SUBCONTRACT MODIFICATION
0001
Subcontract No : MVA
2004-00001BXTR
Modification No.: 0001
Effective Date: Upon Subcontract
Award
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Subcontractor:
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Baxter
Healthcare SA
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Hertistrasse
2
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H-8304
Wallisellen, Switzerland
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Description of
Modification:
Option
Exercise of Specified Contract Line Items (CLIN’s)
(See
Page 2.)
Authority for modification:
Unilateral modification under paragraph H.25
Total Value of this Modification:
$ *****
For: ACAMBIS, INC.
Execution
Date: September 30, 2004
/s/ Roger J. McAvoy
Roger J. McAvoy
Vice President,
Contracts and Legal Affairs