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EXHIBIT 10.1 STOCK PURCHASE AGREEMENT

Stock Purchase Agreement

EXHIBIT 10.1   STOCK PURCHASE AGREEMENT | Document Parties: Neurocrine Biosciences, Inc.,  | Wyeth Holdings Corporation You are currently viewing:
This Stock Purchase Agreement involves

Neurocrine Biosciences, Inc., | Wyeth Holdings Corporation

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Title: EXHIBIT 10.1 STOCK PURCHASE AGREEMENT
Governing Law: California     Date: 3/17/2004
Industry: Biotechnology and Drugs     Law Firm: Latham & Watkins LLP     Sector: Healthcare

EXHIBIT 10.1   STOCK PURCHASE AGREEMENT, Parties: neurocrine biosciences  inc.   , wyeth holdings corporation
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                                                                    EXHIBIT 10.1

 

                            STOCK PURCHASE AGREEMENT

 

         This STOCK PURCHASE AGREEMENT (this "Agreement") is made and entered

into as of March 15, 2004 by and among Neurocrine Biosciences, Inc., a Delaware

corporation (the "Company"), and Wyeth Holdings Corporation (formerly known as

"American Cyanamid Company"), a Maine corporation (the "Investor"). The Investor

and the Company are referred to herein as the "Parties."

 

                              W I T N E S S E T H:

 

         WHEREAS, the Investor and the Company have entered into that certain

Assignment and License Agreement dated February 26, 2004 (the "Assignment

Agreement"), which Assignment Agreement provides, inter alia, for the Parties to

enter into this Agreement, pursuant to which the Company will issue to the

Investor shares of its common stock, $.001 par value per share ("Common Stock"),

as partial consideration for the rights and obligations assigned by the Investor

to the Company under Article 2 of the Assignment Agreement and the licenses

granted by the Investor to the Company under Article 3 of the Assignment

Agreement;

 

         WHEREAS, the Company and Investor wish to set forth certain terms

relating to the issuance of the shares of Common Stock.

 

         NOW, THEREFORE, in consideration of the premises and the mutual

promises herein made, and in consideration of the representations, warranties

and covenants herein contained, the Parties agree as follows:

 

         1.        AGREEMENT TO ISSUE STOCK.

 

                  Subject to the terms and conditions of this Agreement, as

partial consideration for the rights and obligations assigned by the Investor to

the Company under Article 2 of the Assignment Agreement and the licenses granted

by the Investor to the Company under Article 3 of the Assignment Agreement, the

Company shall issue and deliver to the Investor at the Closing (as defined

below) Eight Hundred Two Thousand Nine Hundred Ninety-Eight (802,998) shares of

its Common Stock; provided that if the sum of the aggregate value of such shares

of Common Stock on the Closing Date (as defined below) plus the aggregate value

of any other Common Stock as of the Closing Date held by the Investor or its

Affiliate as of the Closing Date (including without limitation the 4,186 shares

of Common Stock held by the Investor or its Affiliate as of the Signature Date)

plus the aggregate value of any Common Stock as of the Closing Date purchasable

by the Investor or its Affiliate pursuant to any warrant (including without

limitation the 19,950 shares of Common Stock purchasable by the Investor or its

Affiliate under its existing warrant) is equal to or greater than $50,000,000,

the Company will (i) issue to the Investor a number of shares of Common Stock

(rounded down to the next whole share) that, when added to the number of other

shares of Common Stock held by the Investor or its Affiliate as of the Closing

Date plus the number of shares of Common Stock purchasable by the Investor or

its Affiliate pursuant to any warrant as of the Closing Date, is equal to

$49,999,995 divided by the closing sale price of the Company's Common Stock on

the Nasdaq National Market on the trading day immediately prior to the Closing

Date and (ii) pay to the

 

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Investor an amount in cash equal to the difference of the aggregate value of

Eight Hundred Two Thousand Nine Hundred Ninety-Eight (802,998) shares of Common

Stock minus the aggregate value of the number of shares of Common Stock issuable

pursuant to this proviso. For purposes of this Section 1, the value of a number

of shares of the Company's Common Stock as of the Closing Date shall be

calculated by multiplying the number of shares by the closing sale price of the

Company's Common Stock on the Nasdaq National Market on the trading day

immediately prior to the Closing Date. The shares of the Company's Common Stock

to be issued pursuant to this Section 1 are referred to herein as the "Shares."

 

         2.        CLOSING.

 

                   The issuance and delivery of the Shares (the "Closing") will

take place at the offices of the Investor, 500 Arcola Road, Collegeville,

Pennsylvania 19426, on the date hereof (the "Closing Date").

 

         3.        REPRESENTATIONS AND WARRANTIES OF THE COMPANY.

 

                  The Company hereby represents and warrants to the Investor

that the statements in the following paragraphs of this Section 3 are true and

correct:

 

                  3.1       Organization, Good Standing and Qualification. The

Company is a corporation duly organized, validly existing and in good standing

under the laws of the State of Delaware. Schedule 3.1 attached hereto sets forth

the name and jurisdiction of organization of each of the Company's subsidiaries

("Subsidiaries"). The Company and each of its Subsidiaries are duly authorized

to conduct business and are in good standing under the laws of each jurisdiction

where such qualification is required, except where the failure to be so

qualified would not have a material adverse effect on the business, properties,

financial condition, operations or results of operations of the Company and its

Subsidiaries, taken as a whole (a "Material Adverse Effect"). Neither the

Company nor any of its Subsidiaries is in default under or in violation of any

provision of its charter or bylaws. The Company has full power and authority to

execute and deliver this Agreement and to perform its obligations hereunder. The

Company and each of the Subsidiaries have full power and authority to carry on

their respective businesses as currently conducted.

 

                  3.2       Authorization; Enforceability. All corporate action

on the part of the Company necessary for the authorization, execution and

delivery of this Agreement, the performance of the obligations of the Company at

the Closing, and the issuance and delivery of the Shares has been taken, and

this Agreement has been duly executed and delivered by the Company and

constitutes a legally valid and binding obligation of the Company, enforceable

in accordance with its terms, except as may be limited by (i) applicable

bankruptcy, insolvency, reorganization or other laws of general application

relating to or affecting the enforcement of creditors' rights generally, (ii)

the effect of rules of law governing the availability of equitable remedies and

(iii) the unenforceability under certain circumstances under law or court

decisions of provisions providing for the indemnification of or contribution to

a party with respect to a liability where such indemnification or contribution

is contrary to public policy or prohibited by law.

 

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                  3.3       Valid Issuance of Stock. The Shares have been duly

reserved for issuance and, when issued and delivered in accordance with the

terms of this Agreement for the consideration contemplated herein, (i) will be

duly and validly issued, fully paid and nonassessable and will be free of any

taxes, liens or claims (other than those that may be created by the Investor);

(ii) will be free of any restrictions on transfer other than restrictions on

transfer under applicable federal and state securities laws; (iii) will not be

subject to preemptive rights or similar rights of any stockholders of the

Company; and (iv) will be issued in compliance with all applicable federal and

state securities laws. The Shares will have attached thereto rights (the

"Rights") to purchase Series A Participating Preferred Stock. The Rights have

been and will be issued pursuant to an Amended and Restated Preferred Shares

Rights Agreement dated as of January 11, 2002 between the Company and American

Stock Transfer & Trust Company.

 

                  3.4       Capitalization. The entire authorized capital stock

of the Company consists of 50,000,000 shares of Common Stock, of which

35,334,440 shares were issued and outstanding as of February 27, 2004, and

5,000,000 shares of preferred stock, $.001 par value per share, none of which

are issued and outstanding as of the date hereof. Except as set forth in SEC

Documents (as defined below) and except as granted in the ordinary course of

business pursuant to the Company's 2003 Incentive Stock Plan since the dates of

the SEC Documents, there are no outstanding or authorized warrants, options,

preemptive rights, purchase rights, subscription rights, conversion rights,

exchange rights, or instruments convertible into or exchangeable for, any

unissued shares of capital stock or other equity interest in the Company, or

other contracts or commitments that could require the Company to issue, sell or

otherwise cause to become outstanding any of its capital stock. There are no

outstanding or authorized stock appreciation, phantom stock, profit

participation or similar rights with respect to the Company. Without limiting

the foregoing, no preemptive right, co-sale right, right of first refusal or

other similar right exists with respect to the issuance and sale of the Shares.

Except as set forth in the SEC Documents, there are no stockholders agreements,

voting trusts, proxies or other agreements or understandings with respect to the

voting of the capital stock of the Company.

 

                  3.5       Noncontravention. Neither the execution nor the

delivery of this Agreement, nor the consummation of the transactions

contemplated hereby, will (i) violate any constitution, statute, regulation,

rule, injunction, judgment, order, decree, ruling, charge or other restriction

of any government, governmental agency or court to which the Company is subject,

(ii) violate any provision of the charter or bylaws of the Company (the

"Governing Documents") or (iii) conflict with, result in a breach of, constitute

a default under, result in the acceleration of, create in any party the right to

accelerate, terminate, modify or cancel, or require any notice under any

agreement, contract, lease, license, instrument, or other arrangement to which

the Company is a party or by which the Company is bound or to which any of the

Company's assets is subject (or result in the imposition of any mortgage,

pledge, lien, encumbrance, charge or other security interest upon any of such

assets), except in the case of clause (i) or (iii) above, where such violation,

conflict or default would not have a Material Adverse Effect. Except for (i) the

filing of a Form D with the Securities and Exchange Commission (the "SEC") and

(ii) filings which may be required under state securities laws, the Company does

not need to give any notice to, make any filing with, or obtain any

authorization, consent or approval of any government or governmental agency in

order for the Company and the Investor to consummate the transactions

contemplated by this Agreement.

 

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                  3.6       Reports Filed under the Securities Exchange Act of

1934; Financial Statements. The Company has timely filed or furnished, as

applicable, all reports required to be filed by the Company under the Securities

Exchange Act of 1934, as amended (the "1934 Act"), and the related

certifications required under Sections 302 and 906 of the Sarbanes-Oxley Act of

2002. All such reports filed by the Company in the preceding twelve (12) months

(the "SEC Documents") contain all statements required to be stated therein in

accordance with the 1934 Act and the rules and regulations promulgated

thereunder applicable to the SEC Documents, and the SEC Documents do not contain

any untrue statement of a material fact or omit to state a material fact

required to be stated therein or necessary to make the statements therein not

misleading. Any statements made in any such SEC Documents that are or were

required to be updated or amended have been so updated or amended. As of their

respective dates (except as they have been correctly amended), the financial

statements of the Company included in the SEC Documents complied as to form in

all material respects with applicable accounting requirements and the published

rules and regulations of the SEC with respect thereto. Such financial statements

have been prepared in accordance with generally accepted accounting principles,

consistently applied, during the periods involved (except (a) as may be

otherwise indicated in such financial statements or the notes thereto or (b) in

the case of unaudited interim statements, to the extent they may exclude

footnotes or may be condensed or summary statements) and fairly present the

financial position of the Company as of the dates thereof and the results of its

operations and cash flows for the periods then ended (subject, in the case of

unaudited statements, to normal year-end audit adjustments). Except as set forth

in the SEC Documents, the Company has no liabilities, contingent or otherwise,

other than (i) liabilities incurred in the ordinary course of business

subsequent to the date of such SEC Documents, (ii) obligations under contracts

and commitments incurred in the ordinary course of business and not required

under generally accepted accounting principles to be reflected in such SEC

Documents, which liabilities and obligations referred to in clauses (i) and

(ii), individually or in the aggregate, would not have a Material Adverse

Effect, and (iii) contingent liabilities which, individually or in the

aggregate, could not reasonably be expected to have a Material Adverse Effect.

 

                  3.7       Absence of Litigation. Except as disclosed in the SEC

Documents, there is no action, suit, proceeding, inquiry or investigation before

or by any court, public board, government agency, self-regulatory organization

or body pending or, to the knowledge of the Company, threatened against or

affecting the Company, or any of its Subsidiaries, or any of their directors or

officers in their capacities as such which could reasonably be expected to have

a Material Adverse Effect.

 

                   3.8       Taxes. The Company has filed all tax returns,

reports, forms, schedules and any other documents ("Tax Returns") required to be

filed by or on behalf of the Company, and all such Tax Returns are accurate and

complete in all material respects. The Company has paid all material taxes

(including interest, penalties, additions to tax or other additional amounts

imposed by any taxing authority) shown to be due on such Tax Returns or

otherwise due, except for such taxes that are being contested in good faith and

for which adequate reserves have been provided.

 

                  3.9       No Violations. The Company is not in violation of its

charter, bylaws or other organizational documents, or in violation of any law,

administrative regulation, ordinance

 

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or order of any court or governmental agency, arbitration panel or authority

applicable to the Company, which violation, individually or in the aggregate,

would be reasonably likely to have a Material Adverse Effect, and is not in

default (and there exists no condition which, with or without the passage of

time or giving of notice or otherwise, would constitute a default) in the

performance of any bond, debenture, note or any other evidence of indebtedness

in any indenture, mortgage, deed of trust or any other agreement or instrument

to which the Company is a party or by which the Company is bound or by which the

property of the Company is bound, which would be reasonably likely to have a

Material Adverse Effect.

 

                  3.10      Nasdaq Compliance. The Common Stock is registered

pursuant to Section 12(g) of the 1934 Act, and is listed on the Nasdaq National

Market, and the Company has taken no action designed to, or likely to have the

effect of, terminating the registration of the Common Stock under the 1934 Act

or delisting the Common Stock from the Nasdaq National Market.

 

                  3.11      No Manipulation of Stock. The Company has not taken

any action outside the ordinary course of business designed to or that might

reasonably be expected to cause or result in stabilization or manipulation of

the price of the Common Stock to facilitate the sale or resale of the Shares.

 

                  3.12      No General Solicitation. Neither the Company, nor any

of its affiliates, nor any person acting on its or their behalf, has engaged in

any form of general solicitation or general advertising (within the meaning of

Regulation D under the Securities Act of 1933, as amended (the "1933 Act")) in

connection with the offer or sale of the Shares.

 

                  3.13      Form S-3 Eligibility. The Company is currently, and

at the Closing Date will be, eligible to register the resale of the Shares on a

registration statement on Form S-3 under the 1933 Act. There exist no facts or

circumstances (including without limitation any required approvals or waivers of

any circumstances that may delay or prevent the obtaining of accountant's

consents) that would prohibit or delay the preparation and filing of a

registration statement on Form S-3 with respect to the Shares.

 

                  3.14      Rule 144 Availability. The Company has filed the

reports required to be filed by it under the 1934 Act and the rules and

regulations adopted by the SEC thereunder in order to enable the holders of

unregistered Common Stock to sell such Common Stock without registration under

the 1933 Act within the limitation of the exemptions provided by Rule 144 under

the 1933 Act, as such Rule is currently in effect.

 

          4.        REPRESENTATIONS AND WARRANTIES OF THE INVESTOR.

 

                  The Investor represents and warrants to the Company that the

statements in the following paragraphs of this Section 4 are true and correct:

 

                  4.1       Organization and Qualification. The Investor is a

corporation duly organized, validly existing and in good standing under the laws

of the State of Maine. The Investor has all requisite corporate power and

authority to enter into and perform this Agreement and to carry out the

transactions contemplated by this Agreement.

 

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<PAGE>

 

                  4.2       Authorization. All action on the part of the Investor

necessary for the authorization, execution and delivery of this Agreement and

the performance of all obligations of the Investor hereunder has been taken, and

this Agreement has been duly executed and delivered by the Investor and

constitutes a legally valid and binding obligation of the Investor, enforceable

in accordance with its terms, except as may be limited by (i) applicable

bankruptcy, insolvency, reorganization or other laws of general application

relating to or affecting the enforcement of creditors' rights generally, (ii)

the effect of rules of law governing the availability of equitable remedies and

(iii) the unenforceability under certain circumstances under law or court

decisions of provisions providing for the indemnification of or contribution to

a party with respect to a liability where such indemnification or contribution

is contrary to public policy or prohibited by law.

 

                  4.3       Purchase for Own Account. The Shares to be purchased

by the Investor hereunder will be acquired for investment for the Investor's own

account, not as a nominee or agent, and not with a view to the public

distribution thereof within the meaning of the 1933 Act, and the Investor has no

present intention of selling or otherwise distributing the same, except in

compliance with the requirements of, or pursuant to a valid exemption from, such

Act. The Investor does not have any contract, undertaking, agreement or

arrangement with any person to sell, transfer or grant participations to such

person or to any third person, with respect to the Shares. The Investor also

represents that it has not been formed for the specific purpose of acquiring the

Shares.

 

                  4.4       Accredited Investor Status. The Investor is an

"accredited investor" within the meaning of Regulation D promulgated under the

1933 Act. By reason of its business and financial experience, sophistication and

knowledge, the Investor is capable of evaluating the risks and merits of the

investment made pursuant to this Agreement. The Investor confirms that it is

able (i) to bear the economic risk of this investment, (ii) to hold the Shares

for an indefinite period of time, and (iii) to bear a complete loss of the

Investor's investment; and the Investor represents that it has sufficient liquid

assets so that the illiquidity associated with this investment will not cause

any undue financial difficulties or affect the Investor's ability to provide for

its current needs and possible financial contingencies.

 

                  4.5       Restricted Securities. The Investor understands that

the Shares are characterized as "restricted securities" under the 1933 Act

inasmuch as they are being acquired from the Company in a transaction not

involving a public offering and that under the 1933 Act and applicable

regulations thereunder such securities may be resold without registration under

the 1933 Act only in certain limited circumstances. In this connection, the

Investor represents that it is familiar with SEC Rule 144, as presently in

effect, and understands the resale limitations imposed thereby and by the 1933

Act. The Investor understands that the Company is under no obligation to

register any of the securities sold hereunder, except as provided in Section 7

below.

 

                  4.6       Due Diligence and No Solicitation. The Investor has

had a reasonable opportunity to conduct due diligence and to ask questions of

and receive answers from the Company and its officers. At no time was the

Investor presented with or solicited by any leaflet, public promotional meeting,

circular, newspaper or magazine article, radio or television advertisement or

any other form of general advertising. Neither such inquiries nor any other due

 

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diligence investigation conducted by Investor or its counsel or any of its

representatives shall modify or affect Investor's right to rely on the Company's

representations and warranties in this Agreement.

 

                  4.7       Further Limitations on Disposition. The Investor

further agrees not to make any disposition of all or any portion of the Shares

unless and until:

 

                           (a)       there is then in effect a registration

statement under the 1933 Act covering such proposed disposition and such

disposition is made in accordance with such registration statement; or

 

                           (b)       (i) the Investor shall have notified the

Company of the proposed disposition and shall have furnished the Company with a

statement of the circumstances surrounding the proposed disposition, which in

the case of a sale to be made pursuant to Rule 144 shall be limited to customary

representations regarding compliance with the requirements of Rule 144 regarding

volume, manner of sale and other matters, and (ii) the Investor shall have

furnished the Company at the Investor's expense an opinion of in house or

outside counsel (as determined by the Investor), reasonably satisfactory to the

Company that such disposition will not require registration of such securities

under the 1933 Act; provided that the Company shall not require an opinion of

counsel for routine sales of shares pursuant to Rule 144 or any sale of shares

pursuant to Rule 144(k).

 

                  Notwithstanding the foregoing provisions of this Section 4.7

or any other provision of this Article 4 or this Agreement, the Parties

acknowledge and agree that the Investor may contribute or otherwise transfer the

Shares without consideration to a corporation that is the direct or indirect

parent of the Investor or to any subsidiary of the Investor or such corporate

parent.

 

                  4.8       Legends. It is understood that the certificates

evidencing the Shares will bear the legends set forth below:

 

                           (a)       THE SECURITIES REPRESENTED HEREBY HAVE NOT

BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "ACT"), OR

UNDER THE SECURITIES LAWS OF ANY STATE. THESE SECURITIES ARE SUBJECT TO

RESTRICTIONS ON TRANSFERABILITY AND RESALE AND MAY NOT BE TRANSFERRED OR RESOLD

EXCEPT AS PERMITTED UNDER THE ACT AND THE APPLICABLE STATE SECURITIES LAWS,

PURSUANT TO REGISTRATION OR EXEMPTION THEREFROM.

 

                           (b)       Any legend required by the laws of the State

of California, including any legend required by the California Department of

Corporations.

 

The legend set forth above shall be removed and the Company shall issue a

certificate without such legend to the holder of Shares upon which it is

stamped, if (a) the Shares represented by such certificate have been sold

pursuant to an effective registration statement under the 1933 Act or (b) in

connection with the resale of such Shares, such holder provides the Company with

an opinion of in house or outside counsel (as determined by the Investor), in

form, substance and

 

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scope customary for opinions of counsel in comparable transactions, to the

effect that a public sale or transfer of such Security may be made without

registration under the 1933 Act or (c) such holder provides the Company with

reasonable assurances that such Shares have been sold under Rule 144 or can be

sold under Rule 144(k).

 

         5.        COVENANTS.

 

                  The Company and the Investor agree as follows:

 

                  5.1       Form D. The Company agrees to file a notice of sale

on Form D with respect to the Shares as required under Regulation D promulgated

under the 1933 Act and to provide a copy thereof to Investor promptly after such

filing.

 

                  5.2       No Integrated Offerings. The Company shall not make

any offers or sales of any security (other than the Shares) under circumstances

that would require registration of the Shares being offered or sold hereunder

under the 1933 Act or cause this offering of Shares to be integrated with any

other offering of securities by the Company.

 

                  5.3       Transfer Taxes. On the Closing Date, all stock

transfer or other


 
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