AMENDMENT NO. 2 TO THE XOMA LTD. 1998 EMPLOYEE SHARE PURCHASE PLAN

Stock Purchase Agreement

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Title: AMENDMENT NO. 2 TO THE XOMA LTD. 1998 EMPLOYEE SHARE PURCHASE PLAN
Date: 3/15/2005
Industry: Biotechnology and Drugs

Exhibit 10.5B

AMENDMENT NO. 2 TO THE XOMA LTD.

1998 EMPLOYEE SHARE PURCHASE PLAN

The XOMA Ltd. 1998 Employee Share Purchase Plan, as amended (the “Plan”), is hereby amended, effective as of January 1, 2005, as follows:

Section 2(h) of the Plan is amended to read as follows:

“(h) “ Offering Periods” shall mean consecutive three (3) month periods commencing onc

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