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FIRST AMENDMENT AND CONSENT TO LOAN AND SECURITY AGREEMENT

Security Agreement

FIRST AMENDMENT AND CONSENT TO LOAN AND SECURITY AGREEMENT | Document Parties: ARCA BIOPHARMA, INC. | ARCA Discovery, Inc | Colorado, Inc | Silicon Valley Bank You are currently viewing:
This Security Agreement involves

ARCA BIOPHARMA, INC. | ARCA Discovery, Inc | Colorado, Inc | Silicon Valley Bank

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Title: FIRST AMENDMENT AND CONSENT TO LOAN AND SECURITY AGREEMENT
Date: 3/27/2009
Industry: Biotechnology and Drugs     Sector: Healthcare

FIRST AMENDMENT AND CONSENT TO LOAN AND SECURITY AGREEMENT, Parties: arca biopharma  inc. , arca discovery  inc , colorado  inc , silicon valley bank
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Exhibit 10.11

FIRST AMENDMENT AND CONSENT

TO

LOAN AND SECURITY AGREEMENT

THIS FIRST AMENDMENT AND CONSENT to Loan and Security Agreement (this “Amendment”) is entered into this 21st day of January, 2009, by and between Silicon Valley Bank (“Bank”) and ARCA biopharma, Inc. (f/k/a ARCA Discovery, Inc.), a Delaware corporation (“Borrower”) whose address is 8001 Arista Place, Suite 200, Broomfield, CO 80021.

RECITALS

A. Bank and Borrower have entered into that certain Loan and Security Agreement dated as of July 17, 2007 (as the same may from time to time be amended, modified, supplemented or restated, the “Loan Agreement”).

B. Bank has extended credit to Borrower for the purposes permitted in the Loan Agreement.

C. Borrower has requested that Bank amend the Loan Agreement to (i) revise the maturity date of the outstanding GC Line B Advances and (ii) make certain other revisions to the Loan Agreement as more fully set forth herein.

D. Borrower has also requested that Bank consent to the merger of a wholly-owned subsidiary of Nuvelo, Inc., a Delaware corporation (“Nuvelo”), with and into Borrower, with Borrower being the surviving corporation, pursuant to that certain Agreement and Plan of Reorganization, dated September 24, 2008, as amended by that certain Amendment No. 1 to Agreement and Plan of Reorganization, dated October 28, 2008 (as may be further amended, modified, supplemented or restate from time to time, the “Merger Agreement”, with the transactions contemplated under such Merger Agreement being hereinafter referred to as, the “Merger Transactions”). Borrower has also requested that the Bank consent to the change of Borrower’s name to ARCA biopharma Colorado, Inc. (the “Name Change”).

E. Bank has agreed to so amend certain provisions of the Loan Agreement and consent to the Merger Transactions, but only to the extent, in accordance with the terms, subject to the conditions and in reliance upon the representations and warranties set forth below.

A GREEMENT

N OW , T HEREFORE , in consideration of the foregoing recitals and other good and valuable consideration, the receipt and adequacy of which is hereby acknowledged, and intending to be legally bound, the parties hereto agree as follows:

1. Definitions. Capitalized terms used but not defined in this Amendment shall have the meanings given to them in the Loan Agreement.

2. Amendments to Loan Agreement.

2.1 Section 6.2 of the Loan Agreement is hereby deleted in its entirety and replaced with the following:

6.2 Financial Statements, Reports, Certificates . Deliver to Bank: (i) within five (5) days of delivery, copies of all statements, reports and notices made


generally available to the security holders or to any holders of Subordinated Debt of Borrower’s parent company, Nuvelo, Inc.(“Parent”) , (ii) within five (5) days of filing, all reports on Form 10-K, 10-Q and 8-K filed with the Securities and Exchange Commission for Borrower’s parent company, Nuvelo, Inc. (the “Parent”) or a link thereto on Parent’s or another website on the Internet; (iii) a prompt report of any legal actions pending or threatened against Borrower or any of its Subsidiaries that could result in damages or costs to Borrower or any of its Subsidiaries of One Hundred Thousand Dollars ($100,000) or more; and (iv)   budgets, sales projections, operating plans and other financial information reasonably requested by Bank.”

2.2 The definition of “GC Line B Tranche Two maturity Date” in Section 13.1 of the Loan Agreement is hereby deleted in its entirety and replaced with the following:

GC Line B Tranche Two Maturity Date ” is March 23, 2009.

2.3 Borrower agrees that the Initial Warrant and Additional Warrants (collectively, the “Warrants”) issued to Bank pursuant to Section 6.8 of the Loan Agreement will be assumed by Nuvelo. Such Warrants shall be exercisable for the same securities, cash, and property as would be payable for the shares issuable upon exercise of the Warrants as if such shares were outstanding on the record date for the Merger Transactions and subsequent closing. The Warrant Price (as defined in the Warrants) shall be adjusted accordingly.

3. Consent. Subject to the conditions set forth in this Amendment, Bank hereby consents to the Merger Transactions and Name Change and agrees that the Merger Transactions and the Name Change, in and of themselves, shall not constitute an Event of Default pursuant to Sections 7.2 or 7.3 of the Loan Agreement. Borrower will deliver immediate notice to Bank if the M


 
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