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MICROISLET, INC. 2005 EQUITY INCENTIVE PLAN STOCK OPTION AGREEMENT

Option Agreement

MICROISLET, INC.
                           2005 EQUITY INCENTIVE PLAN
                             STOCK OPTION AGREEMENT | Document Parties: MICROISLET INC You are currently viewing:
This Option Agreement involves

MICROISLET INC

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Title: MICROISLET, INC. 2005 EQUITY INCENTIVE PLAN STOCK OPTION AGREEMENT
Date: 4/11/2008
Industry: Biotechnology and Drugs     Sector: Healthcare

MICROISLET, INC.
                           2005 EQUITY INCENTIVE PLAN
                             STOCK OPTION AGREEMENT, Parties: microislet inc
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<PAGE>
                                                                   Exhibit 10.21

                                    MICROISLET, INC. 2005 EQUITY INCENTIVE PLAN
                                               FORM:      STOCK OPTION AGREEMENT
                                         APPROVED BY:      COMPENSATION COMMITTEE
                                            VERSION:               DECEMBER 2007


                                MICROISLET, INC.
                           2005 EQUITY INCENTIVE PLAN
                             STOCK OPTION AGREEMENT
                             ----------------------

                  Unless otherwise defined herein, the terms defined in the
MicroIslet, Inc. 2005 Equity Incentive Plan (the "Plan") shall have the same
defined meanings in this Option Agreement.

I.        NOTICE OF STOCK OPTION GRANT.
         -----------------------------

         You have been granted an option to purchase Common Stock, subject to
the terms and conditions of the Plan and this Option Agreement, as follows:

         Name of Optionee:                   ____________________________________

         Total Number of Shares Granted:     ____________________________________

         Type of Option:                     _____ Incentive Stock Option

                                            __X__ Nonstatutory Stock Option


         Exercise Price per Share:           $___________________________________

         Grant Date:                         ____________________________________

          Vesting Commencement Date:          ____________________________________

         Vesting Schedule:                   This option may be exercised, in
                                            whole or in part, in accordance with
                                             the following schedule:

                                            1/6 of the Shares subject to the
                                            option shall vest 6 months after the
                                            Vesting Commencement Date, and 1/36
                                            of the Shares subject to the option
                                            shall vest each month thereafter,
                                            subject to the optionee continuing
                                            to be a Service Provider on such
                                            dates.

         Termination Period:                 This option may be exercised for
                                             three months after the optionee
                                            ceases to be a Service Provider. The
                                            Administrator determines when the
                                            optionee incurs a Termination of
                                            Service for this purpose. Upon the
                                            death or Total and Permanent
                                            Disability of the optionee, this
                                             option may be exercised for 12
                                            months after the optionee ceases to
                                            be a Service Provider. In no event

<PAGE>

                                             shall this option be exercised later
                                            than the Term/Expiration Date
                                            provided for below. These time
                                            periods may be extended as set forth
                                            in Section II.I and Section II.J
                                            below.

         Term/Expiration Date:               10 years after Grant Date

II.       AGREEMENT.
          ----------

         A. GRANT OF OPTION. The Administrator hereby grants to the optionee
named in the Notice of Stock Option Grant attached as Part I of this Option
Agreement (the "Optionee") an option (the "Option") to purchase the number of
Shares, as set forth in the Notice of Stock Option Grant, at the exercise price
per Share set forth in the Notice of Stock Option Grant (the "Exercise Price"),
subject to the terms and conditions of this Option Agreement and the Plan. This
Option is intended to be an Incentive Stock Option ("ISO") or a Nonstatutory
Stock Option ("NSO"), as provided in the Notice of Stock Option Grant.

         B. EXERCISE OF OPTION.

                  1. VESTING/RIGHT TO EXERCISE. This Option is exercisable
during its term in accordance with the Vesting Schedule set forth in the Notice
of Stock Option Grant, this Option Agreement and the applicable provisions of
the Plan. This Option will in no event become exercisable for additional Shares
after a Termination of Service for any reason. Notwithstanding the foregoing,
this Option becomes exercisable in full if the Company is subject to a Change in
Control before the Optionee's Termination of Service, and the Optionee is
subject to an Involuntary Termination (defined below) in anticipation of or
within 12 months after the Change in Control. For purposes of this Option, the
term "Change in Control" shall not include any underwritten public offering of
Shares registered under the Securities Act of 1933, as amended (the "Act"). This
Option may also become exercisable in accordance with Section II.J. below.

                  The term "Involuntary Termination" shall mean the Optionee's
Termination of Service by reason of the involuntary discharge of the Optionee by
the Company (or the Affiliate employing him or her) for reasons other than Cause
(defined below), death or Total and Permanent Disability. The term "Cause" shall
mean (1) the Optionee's theft, dishonesty, or falsification of any documents or
records of the Company or any Affiliate; (2) the Optionee's improper use or
disclosure of confidential or proprietary information of the Company or any
Affiliate; (3) any action by the Optionee which has a detrimental effect on the
reputation or business of the Company or any Affiliate; (4) the Optionee's
failure or inability to perform any reasonable assigned duties after written
notice from the Company or an Affiliate, and a reasonable opportunity to cure,
such failure or inability; (5) any material breach by the Optionee of any
employment or service agreement between the Optionee and the Company or an
Affiliate, which breach is not cured pursuant to the terms of such agreement;
(6) the Optionee's conviction (including any plea of guilty or nolo contendere)
of any criminal act which impairs the Optionee's ability to perform his or her
duties with the Company or an Affiliate; or (7) violation of a material Company
policy.

                  2. METHOD OF EXERCISE. This Option is exercisable by
delivering to the Administrator a fully executed "Exercise Notice" or by any
other method approved by the Administrator. The Exercise Notice shall provide
that the Optionee is electing to exercise the Option, the number of Shares in


                                      -2-
<PAGE>

respect of which the Option is being exercised (the "Exercised Shares"), and
such other representations and agreements as may be required by the
Administrator. The Exercise Notice shall be accompanied by payment of the full
aggregate Exercise Price as to all Exercised Shares. This Option shall be deemed
to be exercised upon receipt by the Administrator of such fully executed
Exercise Notice accompanied by such aggregate Exercise Price. The Optionee is
responsible for filing any reports of remittance or other foreign exchange
filings required in order to pay the Exercise Price.

         C. LIMITATION ON EXERCISE. The grant of this Option and the issuance of
Shares upon exercise of this Option is subject to compliance with all Applicable
Laws. This Option may not be exercised if the issuance of Shares upon exercise
would constitute a violation of any Applicable Laws. In addition, this Option
may not be exercised unless (i) a registration statement under the Act is in
effect at the time of exercise of this Option with respect to the Shares or (ii)
in the opinion of legal counsel to the Company, the Shares issuable upon
exercise of this Option may be issued in accordance with the terms of an
applicable exemption from the registration requirements of the Act. THE OPTIONEE
IS CAUTIONED THAT THE OPTION MAY NOT BE EXERCISED UNLESS THE FOREGOING
CONDITIONS ARE SATISFIED. ACCORDINGLY, THE OPTIONEE MAY NOT BE ABLE TO EXERCISE
THE OPTION WHEN DESIRED EVEN THOUGH THE OPTION IS VESTED. As a condition to the
exercise of this Option, the Company may require the Optionee to satisfy any
qualifications that may be necessary or appropriate, to evidence compliance with
any applicable law or regulation and to make any representation or warranty with
respect thereto as may be requested by the Company. Any shares which are issued
pursuant to an exemption from the registration requirements of the Act will be
"restricted securities" as that term is defined in Rule 144 under the Act, and
will bear an appropriate restrictive legend, unless they are registered under
the Act. The Company is under no obligation to register the Shares issuable upon
exercise of this Option.

         D. METHOD OF PAYMENT. Payment of the aggregate Exercise Price shall be
by any of the following methods; provided, however, the payment shall be in
strict compliance with all procedures established by the Administrator:

                  1. cash;

                  2. check or wire transfer;

                  3. consideration received by the Company under a
broker-assisted sale and remittance program acceptable to the Administrator,
also known as a "cashless exercise" (provided that Officers and Directors shall
not be permitted to use this procedure if this procedure would violate Section
402 of the Sarbanes-Oxley  


 
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