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INCENTIVE STOCK OPTION AGREEMENT

Option Agreement

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This Option Agreement involves

Archemix Corp

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Title: INCENTIVE STOCK OPTION AGREEMENT
Governing Law: Delaware     Date: 7/25/2007

INCENTIVE STOCK OPTION AGREEMENT, Parties: archemix corp
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EXHIBIT 10.23

FOR GRANTS TO SENIOR EXECUTIVES

[APPROVED BY THE BOARD OF DIRECTORS 1/05]

INCENTIVE STOCK OPTION AGREEMENT

ARCHEMIX CORP.

AGREEMENT made as of the ___ day of _______ 200_, between Archemix Corp.

(the "Company"), a Delaware corporation having a principal place of business in

Cambridge, Massachusetts, and ____________ of ____________, an employee of the

Company (the "Employee").

WHEREAS, the Company desires to grant to the Employee an Option to purchase

shares of its common stock, $.001 par value per share (the "Shares"), under and

for the purposes set forth in the Company's 2001 Employee, Director and

Consultant Stock Plan (the "Plan");

WHEREAS, the Company and the Employee understand and agree that any terms

used and not defined herein have the same meanings as in the Plan; and

WHEREAS, the Company and the Employee each intend that the Option granted

herein qualify as an ISO.

NOW, THEREFORE, in consideration of the mutual covenants hereinafter set

forth and for other good and valuable consideration, the parties hereto agree as

follows:

1. GRANT OF OPTION.

The Company hereby grants to the Employee the right and option to purchase

all or any part of an aggregate of ________________ Shares, on the terms and

conditions and subject to all the limitations set forth herein, under United

States securities and tax laws, and in the Plan, which is incorporated herein by

reference. The Employee acknowledges receipt of a copy of the Plan.

2. PURCHASE PRICE.

The purchase price of the Shares covered by the Option shall be $____ per

Share, subject to adjustment, as provided in the Plan, in the event of a stock

split, reverse stock split or other events affecting the holders of Shares after

the date hereof (the "Purchase Price"). Payment shall be made in accordance with

Paragraph 8 of the Plan.

3. EXERCISABILITY OF OPTION.

Subject to the terms and conditions set forth in this Agreement and the

Plan, the Option granted hereby shall become exercisable as follows:

<PAGE>

<TABLE>

<S> <C>

On the first anniversary of the date up to _________ Shares

of this Agreement

Every three months thereafter until an additional _________ Shares

the fourth anniversary of this

Agreement.

</TABLE>

Alternatively, at the election of the Employee, the Option may be exercised

in whole or in part at any time as to Shares which have not yet vested in

accordance with the above schedule; provided however, as a condition to

exercising the Option for such unvested Shares, the Employee shall execute a

Restricted Stock Agreement in the form attached hereto as Exhibit C.

The foregoing rights are cumulative and are subject to the other terms and

conditions of this Agreement and the Plan.

4. TERM OF OPTION.

The Option shall terminate ten years from the date of this Agreement or, if

the Employee owns as of the date hereof more than ten percent of the total

combined voting power of all classes of capital stock of the Company or an

Affiliate, five years from the date of this Agreement, but shall be subject to

earlier termination as provided herein or in the Plan.

If the Employee ceases to be an employee of the Company or of an Affiliate

(for any reason other than the death or Disability of the Employee or

termination of the Employee's employment for "cause" as defined in the Plan, the

Option may be exercised, if it has not previously terminated, within three

months after the date the Employee ceases to be an employee of the Company or an

Affiliate, or within the originally prescribed term of the Option, whichever is

earlier, but may not be exercised thereafter. In such event, the Option shall be

exercisable only to the extent that the Option has become exercisable and is in

effect at the date of such cessation of employment.

Notwithstanding the foregoing, in the event of the Employee's Disability or

death within three months after the termination of employment, the Employee or

the Employee's Survivors may exercise the Option within one year after the date

of the Employee's termination of employment, but in no event after the date of

expiration of the term of the Option.

In the event the Employee's employment is terminated by the Employee's

employer for "cause" as defined in the Plan, the Employee's right to exercise

any unexercised portion of this Option shall cease immediately as of the time

the Employee is notified his or her employment is terminated for "cause," and

this Option shall thereupon terminate. Notwithstanding anything herein to the

contrary, if subsequent to the Employee's termination as an employee, but prior

to the exercise of the Option, the Board of Directors of the Company determines

that, either prior or subsequent to the Employee's termination, the Employee

engaged in conduct which would constitute "cause," then the Employee shall

immediately cease to have any right to exercise the Option and this Option shall

thereupon terminate.

 

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<PAGE>

In the event of the Disability of the Employee, as determined in accordance

with the Plan, the Option shall be exercisable within one year after the

Employee's termination of employment or, if earlier, within the term originally

prescribed by the Option. In such event, the Option shall be exercisable:

(a) to the extent that the Option has become exercisable but has not been

exercised as of the date of Disability; and

(b) in the event rights to exercise the Option accrue periodically, to the

extent of a pro rata portion through the date of Disability of any

additional vesting rights that would have accrued on the next vesting

date had the Employee not become Disabled. The proration shall be

based upon the number of days accrued in the current vesting period

prior to the date of Disability.

In the event of the death of the Employee while an employee of the Company

or of an Affiliate, the Option shall be exercisable by the Employee's Survivors

within one year after the date of death of the Employee or, if earlier, within

the originally prescribed term of the Option. In such event, the Option shall be

exercisable:

(x) to the extent that the Option has become exercisable but has not been

exercised as of the date of death; and

(y) in the event rights to exercise the Option accrue periodically, to the

extent of a pro rata portion through the date of death of any

additional vesting rights that would have accrued on the next vesting

date had the Employee not died. The proration shall be based upon the

number of days accrued in the current vesting period prior to the

Employee's date of death.

5. METHOD OF EXERCISING OPTION.

Subject to the terms and conditions of this Agreement, the Option may be

exercised by written notice to the Company or its designee, in substantially the

form of Exhibit A attached hereto. Such notice shall state the number of Shares

with respect to which the Option is being exercised and shall be signed by the

person exercising the Option. Payment of the Purchase Price for such Shares

shall be made in accordance with Paragraph 8 of the Plan. The Company shall

deliver a certificate or certificates representing such Shares as soon as

practicable after the notice shall be received, provided, however, that the

Company may delay issuance of such Shares until completion of any action or

obtaining of any consent, which the Company deems necessary under any applicable

law (including, without limitation, state securities or "blue sky" laws). The

certificate or certificates for the Shares as to which the Option shall have

been so exercised shall be registered in the Company's share register in the

name of the person so exercising the Option (or, if the Option shall be

exercised by the Employee and if the Employee shall so request in the notice

exercising the Option, shall be registered in the name of the Employee and

another person jointly, with right of survivorship) and shall be delivered as

provided above to or upon the written order of the person exercising the Option.

In the event the

 

3

<PAGE>

Option shall be exercised, pursuant to Section 4 hereof, by any person other

than the Employee, such notice shall be accompanied by appropriate proof of the

right of such person to exercise the Option. All Shares that shall be purchased

upon the exercise of the Option as provided herein shall be fully paid and

nonassessable.

6. PARTIAL EXERCISE.

Exercise of this Option to the extent above stated may be made in part at

any time and from time to time within the above limits, except that no

fractional share shall be issued pursuant to this Option.

7. NON-ASSIGNABILITY.

The Option shall not be transferable by the Employee otherwise than by will

or by the laws of descent and distribution. The Option shall be exercisable,

during the Employee's lifetime, only by the Employee (or, in the event of legal

incapacity or incompetency, by the Employee's guardian or representative) and

shall not be assigned, pledged or hypothecated in any way (whether by operation

of law or otherwise) and shall not be subject to execution, attachment or

similar process. Any attempted transfer, assignment, pledge, hypothecation or

other disposition of the Option or of any rights granted hereunder contrary to

the provisions of this Section 7, or the levy of any attachment or similar

process upon the Option shall be null and void.

8. NO RIGHTS AS STOCKHOLDER UNTIL EXERCISE.

The Employee shall have no rights as a stockholder with respect to Shares

subject to this Agreement until registration of the Shares in the Company's

share register in the name of the Employee. Except as is expressly provided in

the Plan with respect to certain changes in the capitalization of the Company,

no adjustment shall be made for dividends or similar rights for which the record

date is prior to the date of such registration.

9. ADJUSTMENTS.

The Plan contains provisions covering the treatment of Options in a number

of contingencies such as stock splits and mergers. Provisions in the Plan for

adjustment with respect to stock subject to Options and the related provisions

with respect to successors to the business of the Company are hereby made

applicable hereunder and are incorporated herein by reference.

10. TAXES.

The Employee acknowledges that any income or other taxes due from him or

her with respect to this Option or the Shares issuable pursuant to this Option

shall be the Employee's responsibility.

 

4

<PAGE>

In the event of a Disqualifying Disposition (as defined in Section 15

below) or if the Option is converted into a Non-Qualified Option and such

Non-Qualified Option is exercised, the Company may withhold from the Employee's

remuneration, if any, the minimum statutory amount of federal, state and local

withholding taxes attributable to such amount that is considered compensation

includable in such person's gross income. At the Company's discretion, the

amount required to be withheld may be withheld in cash from such remuneration,

or in kind from the Shares otherwise deliverable to the Employee on exercise of

the Option. The Employee further agrees that, if the Company does not withhold

an amount from the Employee's remuneration sufficient to satisfy the Company's

income tax withholding obligation, the Employee will reimburse the Company on

demand, in cash, for the amount under-withheld.

11. PURCHASE FOR INVESTMENT.

Unless the offering and sale of the Shares to be issued upon the particular

exercise of the Option shall have been effectively registered under the

Securities Act of 1933, as now in force or hereafter amended (the "1933 Act"),

the Company shall be under no obligation to issue the Shares covered by such

exercise unless and until the following conditions have been fulfilled:

(a) The person(s) who exercise the Option shall warrant to the Company, at

the time of such exercise, that such person(s) are acquiring such

Shares for their own respective accounts, for investment, and not with

a view to, or for sale in connection with, the distribution of any

such Shares, in which event the person(s) acquiring such Shares shall

be bound by the provisions of the following legend which shall be

endorsed upon the certificate(s) evidencing the Shares issued pursuant

to such exercise:

"The shares represented by this certificate have been taken for

investment and they may not be sold or otherwise transferred by

any person, including a pledgee, unless (1) either (a) a

Registration Statement with respect to such shares shall be

effective under the Securities Act of 1933, as amended, or (b)

the Company shall have received an opinion of counsel

satisfactory to it that an exemption from registration under such

Act is then available, and (2) there shall have been compliance

with all applicable state securities laws;" and

(b) If the Company so requires, the Company shall have received an opinion

of its counsel that the Shares may be issued upon such particular

exercise in compliance with the 1933 Act without registration

thereunder. Without limiting the generality of the foregoing, the

Company may delay issuance of the Shares until completion of any

action or obtaining of any consent, which the Company deems necessary

under any applicable law (including without limitation state

securities or "blue sky" laws).

12. RESTRICTIONS ON TRANSFER OF SHARES.

 

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<PAGE>

12.1 The Shares acquired by the Employee pursuant to the exercise of the

Option granted hereby shall not be transferred by the Employee except as

permitted herein.

12.2 In the event of the Employee's termination of employment for any

reason, the Company shall have the option, but not the obligation, to repurchase

all or any part of the Shares issued pursuant to this Agreement (including,

without limitation, Shares purchased after termination of employment, Disability

or death in accordance with Section 4 hereof). In the event the Company does

not, upon the termination of employment of the Employee (as described above),

exercise its option pursuant to this Section 12.2, the restrictions set forth in

the balance of this Agreement shall not thereby lapse, and the Employee for

himself or herself, his or her heirs, legatees, executors, administrators and

other successors in interest, agrees that the Shares shall remain subject to

such restrictions. The following provisions shall apply to a repurchase under

this Section 12.2:

(i) The per share repurchase price of the Shares to be sold to the Company

upon exercise of its option under this Section 12.2 shall be equal to

the Fair Market Value of each such Share determined in accordance with

the Plan as of the date of termination of employment.

(ii) The Company's option to repurchase the Employee's Shares in the event

of termination of employment shall be valid for a period of 18 months

commencing with the date of such termination of employment.

(iii) In the event the Company shall be entitled to and shall elect to

exercise its option to repurchase the Employee's Shares under this

Section 12.2, the Company shall notify the Employee, or in case of

death, his or her Survivor, in writing of its intent to repurchase the

Shares. Such written notice may be mailed by the Company up to and

including the last day of the time period provided for in Section

12.2(ii) for exercise of the Company's option to repurchase.

(iv) The written notice to the Employee shall specify the address at, and

the time and date on, which payment of the repurchase price is to be

made (the "Closing"). The date specified shall not be less than ten

days nor more than 60 days from the date of the mailing of the notice,

and the Employee or his or her successor in interest with respect to

the Shares shall have no further rights as the owner thereof from and

after the date specified in the notice. At the Closing, the repurchase

price shall be delivered to the Employee or his or her successor in

interest and the Shares being purchased, duly endorsed for transfer,

shall, to the extent that they are not then in the possession of the

Company, be delivered to the Company by the Employee or his or her

successor in interest.

12.3 It shall be a condition precedent to the validity of any sale or other

transfer of any Shares by the Employee that the following restrictions be

complied with (except as hereinafter otherwise provided):

 

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<PAGE>

(i) No Shares owned by the Employee may be sold, pledged or otherwise

transferred (including by gift or devise) to any person or entity,

voluntarily, or by operation of law, except in accordance with the

terms and conditions hereinafter set forth.

(ii) Before selling or otherwise transferring all or part of the Shares,

the Employee shall give written notice of such intention to the

Company, which notice shall include the name of the proposed

transferee, the proposed purchase price per share, the terms of

payment of such purchase price and all other matters relating to such

sale or transfer and shall be accompanied by a copy of the binding

written agreement of the proposed transferee to purchase the Shares of

the Employee. Such notice shall constitute a binding offer by the

Employee to sell to the Company such number of the Shares then held by

the Employee as are proposed to be sold in the notice at the monetary

price per share designated in such notice, payable on the terms

offered to the Employee by the proposed transferee (provided, however,

that the Company shall not be required to meet any non-monetary terms

of the proposed transfer, including, without limitation, delivery of

other securities in exchange for the Shares proposed to be sold). The

Company shall give written notice to the Employee as to whether such

offer has been accepted in whole by the Company within 60 days after

its receipt of written notice from the Employee. The Company may only

accept such offer in whole and may not accept such offer in part. Such

acceptance notice shall fix a time, location and date for the closing

on such purchase ("Closing Date") which shall not be less than ten nor

more than sixty days after the giving of the acceptance notice,

provided, however, if any of the Shares to be sold pursuant to this

Section 12.3 have been held by the Employee for less than six months,

then the Closing Date may be extended by the Company until no more

than ten days after such Shares have been held by the Employee for six

months. The place for such closing shall be at the Company's principal

office. At such closing, the Employee shall accept payment as set

forth herein and shall deliver to the Company in exchange therefor

certificates for the number of Shares stated in the notice accompanied

by duly executed instruments of transfer.

(iii) If the Company shall fail to accept any such offer, the Employee

shall be free to sell all, but not less than all, of the Shares set

forth in his or her notice to the designated transferee at the price

and terms designated in the Employee's notice, provided that (i) such

sale is consummated within six months after the giving of notice by

the Employee to the Company as aforesaid, and (ii) the transferee

first agrees in writing to be bound by the provisions of this Section

12 so that such transferee (and all subsequent transferees) shall

thereafter only be permitted to sell or transfer the Shares in

accordance with the terms hereof. After the expiration of such six

months, the provisions of this Section 12.3 shall again apply with

respect to any proposed voluntary transfer of the Employee's Shares.

(iv) The restrictions on transfer contained in this Section 12.3 shall not

apply to (a) transfers by the Employee to his or her spouse or

children or to a trust for the benefit of his or her spouse or

children, (b) transfers by the Employee to his or her

 

7

<PAGE>

guardian or conservator, and (c) or transfers by the Employee, in the

event of his or her death, to his or her executor(s) or

administrator(s) or to trustee(s) under his or her will (collectively,

"Permitted Transferees"); provided however, that in any such event the

Shares so transferred in the hands of each such Permitted Transferee

shall remain subject to this Agreement, and each such Permitted

Transferee shall so acknowledge in writing as a condition precedent to

the effectiveness of such transfer.

(v) The provisions of this Section 12.3 may be waived by the Company. Any

such waiver may be unconditional or based upon such conditions as the

Company may impose.

12.4 In the event that the Employee or his or her successor in interest

fails to deliver the Shares to be repurchased by the Company under this

Agreement, the Company may elect (a) to establish a segregated account in the

amount of the repurchase price, such account to be turned over to the Employee

or his or her successor in interest upon delivery of such Shares, and (b)

immediately to take such action as is appropriate to transfer record title of

such Shares from the Employee to the Company and to treat the Employee and such

Shares in all respects as if delivery of such Shares had been made as required

by this Agreement. The Employee hereby irrevocably grants the Company a power of

attorney which shall be coupled with an interest for the purpose of effectuating

the preceding sentence.

12.5 If the Company shall pay a stock dividend or declare a stock split on

or with respect to any of its Common Stock, or otherwise distribute securities

of the Company to the holders of its Common Stock, the number of shares of stock

or other securities of Company issued with respect to the shares then subject to

the restrictions contained in this Agreement shall be added to the Shares

subject to the Company's rights to repurchase pursuant to this Agreement. If the

Company shall distribute to its stockholders shares of stock of another

corporation, the shares of stock of such other corporation, distributed with

respect to the Shares then subject to the restrictions contained in this

Agreement, shall be added to the Shares subject to the Company's rights to

repurchase pursuant to this Agreement.

12.6 If the outstanding shares of Common Stock of the Company shall be

subdivided into a greater number of shares or combined into a smaller number of

shares, or in the event of a reclassification of the outstanding shares of

Common Stock of the Company, or if the Company shall be a party to a merger,

consolidation or capital reorganization, there shall be substituted for the

Shares then subject to the restrictions contained in this Agreement such amount

and kind of securities as are issued in such subdivision, combination,

reclassification, merger, consolidation or capital reorganization in respect of

the Shares subject immediately prior thereto to the Company's rights to

repurchase pursuant to this Agreement.

12.7 The Company shall not be required to transfer any Shares on its books

which shall have been sold, assigned or otherwise transferred in violation of

this Agreement, or to treat as owner of such Shares, or to accord the right to

vote as such owner or to pay dividends to, any person or organization to which

any such Shares shall have been so sold, assigned or otherwise transferred, in

violation of this Agreement.

 

8

<PAGE>

12.8 The provisions of Sections 12.1, 12.2 and 12.3 shall terminate upon

the consummation of a public offering of any of the Company's securities

pursuant to a registration statement filed with the Securities and Exchange

Commission.

12.9 The Employee agrees that in the event that the Company effects an

initial public offering of the Common Stock of the Company registered under the

Securities Act, the Shares may not be sold, offered for sale or otherwise

disposed of, directly or indirectly, without the prior written consent of the

managing underwriter(s) of the offering, for such period of time after the

execution of an underwriting agreement in connection with the such offering that

all of the Company's then directors and executive officers agree to be similarly

bound.

12.10 The Employee acknowledges and agrees that neither the Company, its

shareholders nor its directors and officers, has any duty or obligation to

disclose to the Employee any material information regarding the business of the

Company or affecting the value of the Shares before, at the time of, or

following a termination of the employment of the Employee by the Company,

including, without limitation, any information concerning plans for the Company

to make a public offering of its securities or to be acquired by or merged with

or into another firm or entity.

12.11 All certificates representing the Shares to be issued to the Employee

pursuant to this Agreement shall have endorsed thereon a legend substantially as

follows: "The shares represented by this certificate are subject to restrictions

set forth in an Incentive Stock Option Agreement dated _________, 200__ with

this Company, a copy of which Agreement is available for inspection at the

offices of the Company or will be made available upon request."

13. NO OBLIGATION TO EMPLOY.

The Company is not by the Plan or this Option obligated to continue the

Employee as an employee of the Company or an Affiliate. The Employee

acknowledges: (i) that the Plan is discretionary in nature and may be suspended

or terminated by the Company at any time; (ii) that the grant of the Option is a

one-time benefit which does not create any contractual or other right to receive

future grants of options, or benefits in lieu of options; (iii) that all

determinations with respect to any such future grants, including, but not

limited to, the times when options shall be granted, the number of shares

subject to each option, the option price, and the time or times when each option

shall be exercisable, will be at the sole discretion of the Company; (iv) that

the Employee's participation in the Plan is voluntary; (v) that the value of the

Option is an extraordinary item of compensation which is outside the scope of

the Employee's employment contract, if any; and (vi) that the Option is not part

of normal or expected compensation for purposes of calculating any severance,

resignation, redundancy, end of service payments, bonuses, long-service awards,

pension or retirement benefits or similar payments.

14. OPTION IS INTENDED TO BE AN ISO.

The parties each intend that the Option be an ISO so that the Employee (or

the Employee's Survivors) may qualify for the favorable tax treatment provided

to holders of

 

9

<PAGE>

Options that meet the standards of Section 422 of the Code. Any provision of

this Agreement or the Plan which conflicts with the Code so that this Option

would not be deemed an ISO is null and void and any ambiguities shall be

resolved so that the Option qualifies as an ISO. Nonetheless, if the Option is

determined not to be an ISO, the Employee understands that neither the Com


 
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