FIRST AMENDMENT TO OFFICE LEASE AGREEMENT

Exhibit 10.3.5.3

FIRST AMENDMENT TO OFFICE LEASE AGREEMENT

     THIS FIRST AMENDMENT TO OFFICE LEASE AGREEMENT (“First Amendment”) is made this 30th day of June, 2003, between CHASE TOWER ASSOCIATES, L.L.C., a Delaware limited liability company (“Landlord”), and HEALTHCARE FINANCIAL PARTNERS REIT, INC., a Maryland corporation (“Tenant”).

WITNESSETH:

     WHEREAS, by that certain Office Lease Agreement dated December 7, 2001 (the “Lease”), Landlord leased to Tenant, and Tenant leased from Landlord, approximately 10,608 square feet of rentable area, located on the eleventh (11th) floor of the building located at 4445 Willard Avenue, Chevy Chase, Maryland, upon the terms and conditions set forth in the Lease; and

     WHEREAS, Landlord and Tenant desire to modify the terms and conditions of the Lease to establish the Lease Commencement Date thereunder as March 1, 2002, as more particularly set forth herein.

     NOW, THEREFORE, in consideration of the above and the mutual covenants and agreements of the parties hereinafter set forth, and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged by the parties hereto, Landlord and Tenant hereby agree as follows:

     1. Capitalized terms used herein and not otherwise defined shall have the same meanings as those ascribed to them in the Lease.

     2.