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NOTE PURCHASE AGREEMENT

Note Purchase Agreement

NOTE PURCHASE AGREEMENT | Document Parties: AZITHROMYCIN ROYALTY SUB LLC | INSITE VISION INCORPORATED You are currently viewing:
This Note Purchase Agreement involves

AZITHROMYCIN ROYALTY SUB LLC | INSITE VISION INCORPORATED

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Title: NOTE PURCHASE AGREEMENT
Governing Law: New York     Date: 5/12/2008
Industry: Biotechnology and Drugs     Law Firm: Pillsbury Winthrop;O'Melveny Myers     Sector: Healthcare

NOTE PURCHASE AGREEMENT, Parties: azithromycin royalty sub llc , insite vision incorporated
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Exhibit 10.2
 
NOTE PURCHASE AGREEMENT
 
dated February 21, 2008
 
among
 
AZITHROMYCIN ROYALTY SUB LLC,
 
INSITE VISION INCORPORATED
 
and
 
THE PURCHASER NAMED HEREIN
 
$60,000,000 AZITHROMYCIN PHARMA SM SECURED 16% NOTES DUE 2019
 


Table of Contents

   
Page
 
ARTICLE I
INTRODUCTORY
     
Section 1.1
Introductory
1
 
ARTICLE II
RULES OF CONSTRUCTION AND DEFINED TERMS
     
Section 2.1
Rules of Construction and Defined Terms
1
 
ARTICLE III
SALE AND PURCHASE OF ORIGINAL CLASS A NOTES; CLOSING
     
Section 3.1
Sale and Purchase of Original Class A Notes; Closing
2
 
ARTICLE IV
REPRESENTATIONS, WARRANTIES AND AGREEMENTS OF PURCHASER
     
Section 4.1
Purchase for Investment and Restrictions on Resales
3
Section 4.2
Purchaser Status
4
Section 4.3
Source of Funds
4
Section 4.4
Due Diligence
5
Section 4.5
Enforceability of this Note Purchase Agreement
5
Section 4.6
Inspire and Pfizer
5
Section 4.7
Confidentiality Agreement
6
Section 4.8
Tax Matters.
6
 
ARTICLE V
REPRESENTATIONS AND WARRANTIES OF THE ISSUER AND THE PARENT
     
Section 5.1
Disclosure
7
Section 5.2
Enforceability of this Note Purchase Agreement
7
Section 5.3
Securities Laws.
7
Section 5.4
Investment Company Act
8
Section 5.5
Governmental Authorizations
8
Section 5.6
Compliance with ERISA
8
Section 5.7
Use of Proceeds; Margin Regulations
8
Section 5.8
Independent Consultant’s Forecasts
9
Section 5.9
Other Representations and Warranties
9
 
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ARTICLE VI
CONDITIONS TO CLOSING
 
   
Section 6.1
Proceedings
9
Section 6.2
Transactional Opinion
9
Section 6.3
True Sale and Non-Consolidation Opinions
9
Section 6.4
Note Purchaser’s Counsel Opinion
9
Section 6.5
Consummation of Transactions
10
Section 6.6
Certification as to Private Placement Memorandum
10
Section 6.7
Certification as to Note Purchase Agreement
10
Section 6.8
No Actions
10
Section 6.9
Principal Documents
10
Section 6.10
Authorizations
11
Section 6.11
Offering of Original Class A Notes
11
Section 6.12
CUSIP Number
11
Section 6.13
Notice and Instruction to Inspire
11
Section 6.14
Compliance with Laws
11
Section 6.15
Filing of Financing Statements
12
 
ARTICLE VII
ADDITIONAL COVENANTS
     
Section 7.1
DTC
12
Section 7.2
Expenses
12
 
ARTICLE VIII
SURVIVAL OF CERTAIN PROVISIONS
     
Section 8.1
Survival of Certain Provisions
12
 
ARTICLE IX
NOTICES
     
Section 9.1
Notices
13
 
ARTICLE X
SUCCESSORS AND ASSIGNS
     
Section 10.1
Successors and Assigns
13
 
ARTICLE XI
SEVERABILITY
     
Section 11.1
Severability
13
 
ii

 
ARTICLE XII
WAIVER OF JURY TRIAL
     
Section 12.1
WAIVER OF JURY TRIAL
13
 
ARTICLE XIII
GOVERNING LAW; CONSENT TO JURISDICTION
     
Section 13.1
Governing Law; Consent to Jurisdiction.
14
 
ARTICLE XIV
COUNTERPARTS
     
Section 14.1
Counterparts
15
 
ARTICLE XV
TABLE OF CONTENTS AND HEADINGS
     
Section 15.1
Table of Contents and Headings
15
 
ARTICLE XVI
TAX DISCLOSURE
     
Section 16.1
Tax Disclosure
15
 
ARTICLE XVII
MISCELLANEOUS
     
Section 17.1
Limited Recourse
16
     
Annex A
Rules of Construction and Defined Terms
 
Schedule 1
Purchaser
 
iii

 
NOTE PURCHASE AGREEMENT
 
February 21, 2008
 
To the Purchaser named in Schedule 1
 
Ladies and Gentlemen:
 
Azithromycin Royalty Sub LLC, a Delaware limited liability company, and InSite Vision Incorporated, a Delaware corporation, hereby covenant and agree with you as follows:
 
ARTICLE I
INTRODUCTORY
 
Section 1.1   Introductory . The Issuer proposes, subject to the terms and conditions stated herein, to issue and sell to the purchaser named in Schedule 1 (the “ Purchaser ”) and to the Other Note Purchasers the beneficial interests in the Global Notes evidencing $60,000,000 aggregate principal amount of   the Issuer’s Azithromycin PhaRMA SM Secured 16% Notes due 2019. The Original Class A Notes are to be issued pursuant to the Indenture.
 
The Original Class A Notes will be offered and sold to the Purchaser and the Other Note Purchasers (collectively, the “ Note Purchasers ”) in transactions exempt from the registration requirements of the Securities Act. The Issuer has prepared the Private Placement Memorandum describing, among other things, the Original Class A Notes and the security pledged therefor, the Parent’s sale, transfer, conveyance, assignment, contribution and granting to the Issuer of the Purchased Assets and the Parent’s grant of the license under the Residual License Agreement. As described in the Private Placement Memorandum, the Issuer will use the net proceeds from the offering of the Original Class A Notes to fund a portion of the purchase price to obtain the Purchased Assets, to pay the expenses associated with the issuance of the Original Class A Notes and to fund the Interest Reserve Account in the amount of $5,000,000.
 
ARTICLE II
RULES OF CONSTRUCTION AND DEFINED TERMS
 
Section 2.1   Rules of Construction and Defined Terms . The rules of construction set forth in Annex A shall apply to this Note Purchase Agreement and are hereby incorporated by reference into this Note Purchase Agreement as if set forth fully in this Note Purchase Agreement. Capitalized terms used but not otherwise defined in this Note Purchase Agreement shall have the respective meanings given to such terms in Annex A , which is hereby incorporated by reference into this Note Purchase Agreement as if set forth fully in this Note Purchase Agreement. Not all terms defined in Annex A are used in this Note Purchase Agreement.
 
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ARTICLE III
SALE AND PURCHASE OF ORIGINAL CLASS A NOTES; CLOSING
 
Section 3.1   Sale and Purchase of Original Class A Notes; Closing . On the basis of the representations and warranties contained in, and subject to the terms and conditions of, this Note Purchase Agreement, the Issuer agrees to issue and sell the Original Class A Notes to the Purchaser, and the Purchaser agrees to purchase, the principal amount of Original Class A Notes set forth opposite its name on Schedule 1 . The Purchaser will purchase such principal amount of Original Class A Notes at a purchase price equal to 100% of the principal amount thereof (the “ Price ”). Contemporaneously with entering into this Note Purchase Agreement, the Issuer is entering into separate Note Purchase Agreements (the “ Other Agreements ”) substantially identical to this Note Purchase Agreement with other note purchasers (the “ Other Note Purchasers ”), providing for the sale on the Closing Date to each of the Other Note Purchasers of Original Class A Notes in the principal amount specified opposite its name in Schedule 1 to such Other Agreement, at a purchase price equal to 100% of the principal amount thereof (the “ Other Prices ” and, together with the Price, the “ Purchase Price ”). The Issuer shall not be obligated to deliver, and no Note Purchaser shall be required to purchase, any of the Original Class A Notes except upon delivery of and payment for all the Original Class A Notes to be purchased on the Closing Date.
 
On the Closing Date, the Issuer will deliver one or more Global Notes for the account of DTC evidencing the aggregate principal amount of Original Class A Notes to be acquired by all Note Purchasers pursuant to the Note Purchase Agreements. The Issuer will deliver the Global Notes to DTC against payment by each such Note Purchaser of its respective portion of the aggregate Purchase Price for its beneficial interest therein by wire transfer of immediately available funds to the Trustee Closing Account. Delivery to each Note Purchaser of the Original Class A Notes shall be made through the facilities of DTC on the Closing Date, upon payment therefor by each such Note Purchaser of its respective portion of the aggregate Purchase Price by wire transfer of immediately available funds to   the Trustee Closing Account. The Issuer and the Parent shall cause the Trustee to hold all such funds in trust for the Note Purchasers pending completion of the closing of the transactions contemplated by this Note Purchase Agreement. Upon receipt by the Trustee of the aggregate Purchase Price from all Note Purchasers and the satisfaction of the conditions to closing set forth in Article VI, the Issuer and the Parent shall cause the Trustee to disburse the Purchase Price in accordance with Section 3.3 of the Indenture. If the aggregate Purchase Price shall not have been received by the Trustee by 3:30 p.m. (New York City time) on the Closing Date, or if the closing of the transactions contemplated by the Note Purchase Agreements shall not otherwise be capable of being consummated by 3:30 p.m. (New York City time) on the Closing Date, then each Note Purchaser who has paid its respective portion of the Purchase Price shall have the right to instruct the Trustee at or after 3:30 p.m. (New York City time) on the Closing Date to return, and the Issuer and the Parent shall cause the Trustee to return, such portion of the Purchase Price to such Note Purchaser prior to the close of business on the Closing Date or as soon thereafter as reasonably practicable.
 
If the Global Notes shall not be tendered for the benefit of any Note Purchaser for the account of DTC in accordance with the foregoing provisions of this Section 3.1, or any of the conditions specified in Article VI shall not have been fulfilled to the satisfaction of any Note Purchaser, such Note Purchaser shall, at its election, be relieved of all obligations (other than confidentiality obligations) under the applicable Note Purchase Agreement.
 
2

 
ARTICLE IV
REPRESENTATIONS, WARRANTIES AND AGREEMENTS OF PURCHASER
 
The Purchaser agrees and acknowledges that the Issuer, the Parent and the Placement Agent and their respective counsel may rely upon the accuracy and performance of the representations, warranties and agreements of the Purchaser contained in this Article IV.
 
Section 4.1   Purchase for Investment and Restrictions on Resales . The Purchaser:
 
(a)   acknowledges that the Original Class A Notes have not been and will not be registered under the Securities Act or the securities laws of any U.S. state or any other jurisdiction and may not be offered, sold, pledged or otherwise transferred except as set forth in the Private Placement Memorandum, the Indenture and the legend regarding transfers on its Original Class A Notes, in compliance with such securities laws;
 
(b)   agrees that, if it should resell or otherwise transfer the Original Class A Notes, in whole or in part, it will do so only pursuant to an exemption from, or in a transaction not subject to, registration under the Securities Act, applicable state or foreign securities laws, the respective rules and regulations promulgated thereunder and the provisions of this Note Purchase Agreement, and only to a Person whom it reasonably believes, at the time any buy order for such Original Class A Notes is originated, is (i) the Issuer or a subsidiary thereof, (ii) for so long as such Original Class A Notes are eligible for resale pursuant to Rule 144A, a QIB that purchases for its own account or for the account of a QIB, to whom notice is given that the transfer is being made in reliance on Rule 144A, (iii) an Institutional Accredited Investor inside the United States, in respect of which the Purchaser shall reasonably believe that at such time such entity and each other entity, if any, for whom such entity may be acting with respect to the Original Class A Notes has sufficient knowledge and experience in financial and business matters to be capable of evaluating the merits and risks of the purchase of the Original Class A Notes and is able and prepared to bear the economic risk of investing in and holding the Original Class A Notes, that is purchasing such Original Class A Notes for its own account or for the account of such an Institutional Accredited Investor for investment purposes and not with a view to, or for offer or sale in connection with, any distribution in violation of the Securities Act or (iv) an Institutional Accredited Investor outside the United States in an offshore transaction in compliance with Rule 903 or 904 of Regulation S (if available), in each case unless consented to by the Issuer and such offer, sale or other transfer occurs following the Resale Restriction Termination Date;
 
(c)   agrees that it will give to each Person to whom it transfers the Original Class A Notes, in whole or in part, notice of the restrictions on transfer of the Original Class A Notes;
 
(d)   agrees that it will cause any Person to whom it intends to transfer the Original Class A Notes to execute and deliver a resale confidentiality agreement with the Issuer substantially in the form attached to the Indenture and agrees not to make available any confidential information about the Issuer, the Parent, Inspire or Subject Products, including the Private Placement Memorandum, to such Person, and the Purchaser otherwise agrees to comply with the procedures relating to the execution and delivery of such resale confidentiality agreement set forth in the Indenture;
 
3

 
(e)   acknowledges the restrictions and requirements applicable to transfers of the Original Class A Notes described under the heading “Transfer Restrictions” in the Private Placement Memorandum and contained in the Indenture and agrees that it will only offer or sell the Original Class A Notes in accordance with such section and the Indenture and only to Permitted Holders; and
 
(f)   represents that it is purchasing the Original Class A Notes for investment purposes and not with a view to resale or distribution thereof in contravention of the requirements of the Securities Act.
 
Section 4.2   Purchaser Status . The Purchaser represents and warrants that it is purchasing the Original Class A Notes for its own account or an account with respect to which it exercises sole investment discretion and that it and any such account is (i) a QIB and such purchase meets the requirements of Rule 144A under the Securities Act, (ii) an Institutional Accredited Investor, is not acquiring the Original Class A Notes with a view to any resale or distribution thereof other than in accordance with the restrictions set forth below, has sufficient knowledge and experience in financial and business matters to be capable of evaluating the merits and risks of the purchase of the Original Class A Notes and is able and prepared to bear the economic risk of investing in and holding the Original Class A Notes, (iii) an Institutional Accredited Investor that is not a U.S. person and has acquired such Original Class A Notes in an offshore transaction in compliance with Regulation S or (iv) a person or entity consented to by the Issuer in its sole discretion where such offer or sale occurs following the Resale Restriction Termination Date.
 
Section 4.3   Source of Funds . The Purchaser represents, warrants and covenants that either:
 
(a)   no Plan Assets have been used to purchase an Original Class A Note; or
 
(b)   to the extent that Plan Assets are used to purchase an Original Class A Note, one or more statutory or administrative exemptions applies such that the use of such Plan Assets to purchase and hold such Original Class A Notes will not constitute a non-exempt prohibited transaction within the meaning of Section 406 of ERISA or Section 4975 of the Code,
 
In addition, the Purchaser represents, warrants and covenants that either:
 
(i) no assets of a governmental, church or foreign plan have been used to purchase an Original Class A Note; or
 
(ii) to the extent such assets are used, neither the purchase nor holding of the Original Class A Notes will constitute or result in a violation of any Applicable Law that is similar to the prohibited transaction provisions of Section 406 of ERISA or Section 4975 of the Code.
 
4

 
Section 4.4   Due Diligence . The Purchaser acknowledges that (i) it has made, either alone or together with its advisors, such independent investigation of the Issuer, the Parent, Inspire, Pfizer and their respective managements, assets and related matters, and such separate and independent investigation of the Purchased Assets and related matters, as the Purchaser deems to be, or such advisors have advised to be, necessary or advisable in connection with the purchase of the Original Class A Notes pursuant to the transactions contemplated by this Note Purchase Agreement, (ii) it and its advisors have received all information and data that it and such advisors believe to be necessary in order to reach an informed decision as to the advisability of the purchase of the Original Class A Notes pursuant to the transactions contemplated by this Note Purchase Agreement, (iii) it understands the nature of the potential risks and potential rewards of the purchase of the Original Class A Notes, (iv) it is a sophisticated investor with investment experience and, in the event of   a default on the Original Class A Notes, any termination of any of the Principal Documents or termination of the Royalty Payments under the Inspire License Agreement or any liquidation or winding up of the Issuer, has the ability to bear complete loss of its investment, (v) it has such knowledge and experience in financial and business matters that it is capable of evaluating the merits and risks of purchasing the Original Class A Notes and can bear the economic risks of investing in the Original Class A Notes for an indefinite period of time, (vi) it has received and reviewed the Private Placement Memorandum and each of the Transaction Documents and has been furnished by the Parent with an opportunity to review the Principal Documents (except in the case of the Pfizer License Agreement, which has been made available by the Parent only in redacted form) and (vii) it has determined that the rates, prices or amounts and other terms of the purchase and sale of the Original Class A Notes reflect those in the relevant market for similar transactions and it is purchasing the Original Class A Notes with a full understanding of all of the terms, conditions and risks thereof (economic and otherwise), and it is capable of assuming and willing to assume (financially and otherwise) those risks. The Purchaser acknowledges that it has obtained its own attorneys, business advisors and tax advisors as to legal, business and tax advice (or has decided not to obtain such advice) and has not relied on the Issuer, the Parent or the Placement Agent for any such advice. Except for (A) the representations, warranties and covenants made by the Issuer and the Parent in this Note Purchase Agreement and the other Transaction Documents and (B) the legal opinions provided to the Trustee or the Note Purchasers in connection with the transactions contemplated by the Transaction Documents, the Purchaser is relying on its own investigation and analysis in entering into the transactions contemplated hereby.
 
Section 4.5   Enforceability of this Note Purchase Agreement . This Note Purchase Agreement has been duly authorized, executed and delivered by the Purchaser and constitutes the valid, legally binding and enforceable obligations of the Purchaser, except as enforceability may be limited by applicable bankruptcy, insolvency, reorganization, moratorium or similar laws affecting creditors’ rights generally and by general principles of equity.
 
Section 4.6   Inspire and Pfizer . The Purchaser acknowledges and agrees that neither Inspire nor Pfizer is a party to the transactions to which this Note Purchase Agreement relates, neither Inspire nor Pfizer has participated in the preparation of any document related thereto, including the Private Placement Memorandum, and neither Inspire nor Pfizer makes any representations or warranties whatsoever with respect to the transactions contemplated by the Private Placement Memorandum, including the issuance of the Original Class A Notes by the Issuer, the value thereof, the value of the rights transferred by the Parent to the Issuer with respect thereto or the risks associated therewith.
 
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Section 4.7   Confidentiality Agreement . The Purchaser acknowledges and agrees that it is bound by the terms and conditions of the confidentiality agreement referenced in Schedule 1 (including, if the Purchaser is not a party thereto, as if it were a party thereto), agrees to execute any documents reasonably requested by the Issuer to evidence such obligation and acknowledges and agrees that such confidentiality agreement remains in effect and will survive the execution and delivery of this Note Purchase Agreement and the closing of the purchase of the Original Class A Notes pursuant to its terms.
 
Section 4.8   Tax Matters.
 
(a)   The Purchaser represents and warrants that either (i) it is not, and will not become, a partnership, Subchapter S corporation or grantor trust for U.S. federal income tax purposes or (ii) it is a partnership, Subchapter S corporation or grantor trust for U.S. federal income tax purposes but (A) none of the direct or indirect beneficial owners of any of the interests in such holder have allowed or caused, or will allow or cause, 50% or more of the value of such interests to be attributable to such ownership of Notes or (B) such partnership, Subchapter S corporation or grantor trust was not formed with a principal purpose of permitting the Issuer to satisfy the 100-partner limitation in Treasury Regulation Section 1.7704-1(h)(1)(ii) (assuming for this purpose that the Or

 
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