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NOTE PURCHASE AGREEMENT

Note Purchase Agreement

NOTE PURCHASE AGREEMENT
 | Document Parties: VYTERIS HOLDINGS (NEVADA), INC. | Spencer Trask Specialty Group, LLC You are currently viewing:
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VYTERIS HOLDINGS (NEVADA), INC. | Spencer Trask Specialty Group, LLC

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Title: NOTE PURCHASE AGREEMENT
Governing Law: New York     Date: 3/30/2006

NOTE PURCHASE AGREEMENT
, Parties: vyteris holdings (nevada)  inc. , spencer trask specialty group  llc
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                                                                   Exhibit 10.77

                             NOTE PURCHASE AGREEMENT

        NOTE PURCHASE AGREEMENT (this "Agreement"), dated as of February 13,
2006, by and between Vyteris Holdings (Nevada), Inc., a Nevada corporation
("Seller"), and Spencer Trask Specialty Group, LLC, a Delaware limited liability
company ("Buyer").

                              W I T N E S S E T H:
                              - - - - - - - - - -

        WHEREAS, Seller desires to issue to Buyer, and Buyer desires to purchase
from Seller, a convertible subordinated promissory note, substantially in the
form of EXHIBIT A hereto, in the principal amount of $500,000 (the "Note");

        WHEREAS, Seller has agreed to effect the registration of the shares of
Common Stock underlying the Note under the Securities Act of 1933, as amended,
pursuant to a registration statement substantially in the form of EXHIBIT B
hereto (the "Registration Rights Agreement"); and

         WHEREAS, Seller, pursuant to that certain securities purchase agreement
dated as of August 19, 2005, as same may be amended from time to time
("Securities Purchase Agreement") issued a series of senior secured convertible
debentures, including debentures issued after the original issuance date (the
"Debentures") in the aggregate principal amount of $10.5 million (the "Senior
Debt").

        NOW, THEREFORE, in consideration of the mutual covenants and agreements
hereinafter set forth herein and for good and valuable consideration, the
receipt and sufficiency of which are hereby mutually acknowledged, the parties
agree as follows:

        1.       SALE AND PURCHASE OF THE NOTE

        1.1.     SALE AND PURCHASE. Subject to the terms and conditions of this
Agreement, at the Closing (as defined in Section 2.1 hereof), Seller shall issue
to Buyer, and Buyer shall purchase from Seller, for the Purchase Price (as
defined in Section 1.2(a) hereof), the Note.

        1.2.     PURCHASE PRICE AND PAYMENT.

                 (a)      PURCHASE PRICE. The purchase price for the Note shall be
$500,000 (the "Purchase Price").

                (b)      PAYMENT OF PURCHASE PRICE. The Purchase Price shall be
paid to Seller by Buyer on the Closing Date (as defined in Section 2.1 hereof)
via federal funds wire transfer(s) of immediately available funds, in accordance
with written instructions provided to Buyer prior to the date hereof.

        2.       CLOSING.

        2.1.     TIME AND PLACE. The closing of the sale and purchase of the Note
(the "Closing") shall be deemed to take place at the offices of Littman Krooks
LLP, 655 Third

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Avenue, 20th Floor, New York, New York, at 10:00 a.m., local time, on the date
hereof, or at such later time or date as Buyer and Seller may mutually agree in
writing. The date upon which the Closing shall occur is herein called the
"Closing Date".

        2.2.     CLOSING DELIVERIES.

                (a)      SELLER DELIVERIES. At the Closing, Seller shall deliver
or cause to be delivered to Buyer the following:

                        (i)      the duly executed Note;

                        (ii)     the duly executed Registration Rights Agreement;
and

                        (iii)    copies of any consents necessary to effectuate
this Agreement and to consummate the transactions contemplated hereby.

                (b)      BUYER DELIVERY. At the Closing, Buyer shall deliver or
cause to be delivered to Seller the Purchase Price.

        3.       TERMS OF THE NOTE.

        3.1.     AMOUNT. The principal amount of the Note shall be $500,000.

        3.2.     MATURITY. Unless otherwise converted into the Conversion Shares
(as defined in Section 3.4 hereof) in accordance with the provisions hereof, the
Note shall mature on December 1, 2008, unless such date shall be otherwise
extended in writing by Buyer, in its sole discretion (such date, the "Maturity
Date"). On the Maturity Date, unless, and to the extent, converted into
Conversion Shares in accordance with the provisions hereof, all outstanding
principal and any accrued and unpaid interest due and owing under the Note shall
be immediately paid by Seller.

        3.3.     INTEREST; INTEREST RATE; PAYMENT. (a) The Note shall bear
interest (other than interest accruing as a result of a failure by Seller to pay
any amount when due as set forth in clause (b) below) at a rate equal to ten
(10%) percent (the "Interest Rate") per annum on a 360-day year. Interest (other
than interest accruing as a result of a failure by Seller to pay any amount when
due as set forth in subparagraph (b) below) shall be due and payable in cash
semi-annually in arrears following the end of each semi-annual period,
commencing with the semi-annual period ended June 30, 2006, pro rated for
partial periods; PROVIDED, HOWEVER, that any interest accruing on overdue
amounts pursuant to subparagraph (b) of this Section 3.3 shall be payable on
demand.

                (b)      If all or a portion of the principal amount of the Note
or any interest payable thereon shall not be repaid when due whether on the
applicable repayment date, by acceleration or otherwise, such overdue amounts
shall bear interest at a rate per annum that is three percent (3%) above the
Interest Rate (I.E., 13%) from the date of such non-payment until such amount is
paid in full (as well after as before judgment).

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                (c)      All payments to be made by Seller hereunder or pursuant
to the Note shall be made, without setoff or counterclaim, in lawful money of
the United States by check or wire transfer in immediately available funds.

        3.4.     CONVERSION. (a) Subject to Sections 3.4(b) and 3.5 hereof, at
any time prior to the Maturity Date, the Seller shall have the option to convert
the entire principal and interest accrued and owing on the Note, or any portion
of the principal and/or interest thereof, into shares (the "Conversion Shares")
of Common Stock at the Conversion Price. For purposes hereof, "Conversion Price"
shall mean $2.40 per share; PROVIDED, that if at any time on or after the
issuance date of the Note, Seller subdivides (by any stock split, stock
dividend, recapitalization, reorganization, reclassification or otherwise) its
shares of Common Stock into a greater number of shares, then after the date of
record for effecting such subdivision, the Conversion Price shall be
proportionately reduced, or if Seller combines (by reverse stock split,
recapitalization, reorganization, reclassification or otherwise) its shares of
Common Stock into a smaller number of shares, the Conversion Price shall be
proportionately increased.

Upon conversion, Buyer shall be entitled to receive the number of Conversion
Shares calculated by dividing the amount being converted by the Conversion
Price. No fractional shares of Conversion Shares shall be issued upon
conversion. In lieu of any fractional shares to which Buyer would otherwise be
entitled, Seller shall pay cash in an amount equal to such fraction multiplied
by the Conversion Price. The Note shall not be subject to automatic conversion
or to any conversion at the option of Seller.

                (b)      Notwithstanding the provision of Section 3.4(a), if an
equity security or other derivative security convertible or exercisable into an
equity security of the Company ("Applicable Security") is sold in connection
with a Qualified Financing (as hereinafter defined) at any time prior to payment
in full of the principal balance of the Note, all of the principal and interest
due thereunder shall automatically become converted into the Applicable Security
with the same rights and privileges granted to investors in the Qualified
Financing. The number of Applicable Securities received upon conversion pursuant
to this Section 3(b) shall be determined by dividing the aggregate principal
amount due under the Note, together with any accrued but unpaid interest to the
date of conversion, by the price per Applicable Security paid in the Qualified
Financing. For the purposes of the Note, a "Qualified Financing" shall mean the
Company's next private financing of Applicable Securities to investors (i)
yielding aggregate gross proceeds (exclusive of conversion of the Note) to the
Company of at least $1,000,000 and (ii) which does not invoke or trigger the
provisions of Section 4(b) of the Debentures or Section 6(c) of the Warrants (as
such term is defined in the Securities Purchase Agreement.
 
        3.5.     CONVERSION PROCEDURES. In order to exercise the conversion
rights set forth in Section 3.4(a) hereof, Buyer shall surrender the Note,
appropriately endorsed, to Seller at Seller's principal office, accompanied by
written notice to Seller setting forth the amount of principal and interest to
be converted, the name or names (with address(es)) in which the Conversion
Shares issuable upon such conversion shall be issued and registered on the books
of Seller. For purposes hereof, the "Conversion Date" shall be deemed to be the
date the Note and notice is received by Seller for conversion. Within five (5)
business days after the Conversion Date, Seller shall deliver to Buyer (i) a
stock certificate for the Conversion Shares or (ii) a notice certified by
Seller's Secretary that the Conversion Shares due on such conversion have been

                                       3
<PAGE>

issued to and registered on the books of Seller in the name or names specified
by Buyer. In the case of conversion of less than the entire principal of and
interest under the Note, Seller shall cancel said Note and shall execute and
deliver a new Note of like tenor for the unconverted amount of the Note dated
the date of execution by Seller upon initial issuance of the Note
notwithstanding any subsequent substitution.

        3.6.     SUBORDINATION. The Note is expressly and fully subordinated, as
to payment and liquidation, to the payment in full of the Debentures and the
Obligations (as such term is defined in the Securities Purchase Agreement) and
the holder of the Note acknowledges and agrees that the Seller is expressly
restricted from pre-paying any amounts in respect of the principal of the Note
(upon acceleration or otherwise) until payment in full of the Debentures. The
holder of this Note shall not commence any judicial or other collection efforts
or exercise any other remedies prior to the date that is ninety-one (91) days
following the payment in full of the Debentures. The Note is, and is intended to
be, "Subordinated Debt" as such term is defined in the Securities Purchase
Agreement.

        3.7.     PREPAYMENT RIGHTS UPON MERGER, CONSOLIDATION, ETC. (a) If, prior
to the Conversion Date, but subject to the provisions of Section 3.6 above,
Seller proposes to consolidate with, or merge into, another corporation or
entity, or to effect any sale or conveyance to another corporation or entity of
all or substantially all of the assets of Seller, or effect any other corporate
reorganization, in which the stockholders of the Seller immediately prior to
such consolidation, merger or reorganization own capital stock of the entity
surviving such merger, consolidation or reorganization representing less than
fifty (50%) percent of the combined voting power of the outstanding securities
of such entity immediately after such consolidation, merger or reorganization
(collectively, a "Liquidation Event"), then Seller shall provide Buyer with at
least ten (10) days' prior written notice of any such proposed action, and Buyer
will, at its option, have the right to demand immediate prepayment of all
amounts due and owing under the Note. Buyer will give Seller written notice of
such demand within five (5) days after receiving notice of the Liquidation
Event. All amounts (including all accrued and unpaid interest) due and owing
under the Note shall be paid by Seller to Buyer within five (5) days from the
date of such written notice via federal funds wire transfer(s) of immediately
available funds, in accordance with written instructions to be provided to
Seller by Buyer within at least two (2) business days after giving Seller such
written notice. The provisions of this Section 3.7(a) shall similarly apply to
successive consolidations or mergers.

        (b)      Except as set forth in Sections 3.6, 3.7(a) and 9 hereof, Seller
shall not prepay prior to the Maturity Date all or part of this Note without the
express written consent of Buyer.

        3.8      INTENTIONALLY DELETED

        3.9      ASSURANCES WITH RESPECT OF CONVERSION RIGHTS. Seller shall not,
by amendment of its Certificate of Incorporation or By-laws or through any
reorganization, transfer of assets, consolidation, merger, dissolution, issue or
sale of securities or any other voluntary action, avoid or seek to avoid the
observance or performance of any of the terms to be observed or performed
hereunder by Seller but shall at all times in good faith assist in the carrying
out of all the provisions of this Agreement and in taking of all such actions as
may be necessary or appropriate in order to protect the conversion rights of
Buyer against impairment.

                                       4
<PAGE>

        4.        REPRESENTATIONS AND WARRANTIES OF SELLER. Seller hereby
represents and warrants to Buyer as follows:

        4.1      DUE ORGANIZATION AND QUALIFICATION. Seller is a corporation duly
organized, validly existing and in good standing under the laws of the State of
Nevada. Seller has all requisite power and authority to own, lease and operate
its assets and properties and to carry on its business as presently conducted
and as presently contemplated. Seller is duly qualified to transact business and
is in good standing in each jurisdiction in which the nature of its business or
the locations of its property requires such qualification, except where the
failure to do so would not have a material adverse effect on Seller's business,
operations, assets or condition (financial or otherwise).

        4.2      POWER AND AUTHORITY. Seller has the requisite corporate power
and authority to execute and deliver this Agreement and all other agreements
contemplated by this Agreement (including, without limitation, the Note and the
Registration Rights Agreement) and to perform its obligations hereunder and
thereunder. The execution, delivery and performance of this Agreement and all
other agreements contemplated by this Agreement have been duly authorized by all
necessary corporate action on the part of Seller. This Agreement has been duly
executed and delivered by Seller and is the valid and binding obligation of
Seller, enforceable against Seller in accordance with its terms, except as such
enforceability may be limited by applicable bankruptcy, moratorium, insolvency,
reorganization or other similar laws now or hereafter in effect generally
affecting the enforcement of creditors' rights, specific performance, injunctive
or other equitable remedies. When executed and delivered by Seller at the
Closing, each of the Note and the Registration Rights Agreement will be the
valid and binding obligation of Seller, enforceable against Seller in accordance
with its terms, except as such enforceability may be limited by bankruptcy,
moratorium, insolvency, reorganization or other similar laws now or hereafter in
effect generally affecting the enforcement of creditors' rights, specific
performance, injunctive or other equitable remedies.

        4.3.     CAPITALIZATION. The capitalization of the Seller as of the date
of this Agreement, including its authorized capital stock, the number of shares
issued and outstanding, the number of shares issuable and reserved for issuance
pursuant to the Seller's stock option plans and agreements, the number of shares
issuable and reserved for issuance pursuant to securities (other than the Note)
exercisable for, or convertible into or exchangeable for any shares of Common
Stock and the number of shares initially to be reserved for issuance upon
conversion of the Note is set forth on Schedule 4.3 hereto. All issued and
outstanding shares of capital stock of the Seller have been validly issued,
fully paid and non-assessable. Except as disclosed on Schedule 4.3 hereto, the
Seller owns all of the capital stock of each subsidiary, which capital stock is
validly issued, fully paid and non-assessable, and no shares of the capital
stock of the Seller or any of the subsidiaries are subject to preemptive rights
or any other similar rights of the shareholders of the Seller or any such
subsidiary or any liens created by or through the Seller or any such subsidiary.
Except as disclosed on Schedule 4.3 or as contemplated herein, there are no
outstanding options, warrants, scrip, rights to subscribe to, calls or
commitments of any character whatsoever relating to, or securities or rights
convertible in


 
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