THIRD AMENDMENT TO LICENSE AND MANUFACTURING AGREEMENT

Exhibit 10.9

THIRD AMENDMENT TO LICENSE AND MANUFACTURING AGREEMENT

THIS THIRD AMENDMENT TO LICENSE AND MANUFACTURING AGREEMENT ("Third Amendment") is made and entered into as of April 13, 2006 (the "Third Amendment Effective Date"), by and among BioZone Laboratories, Inc., a corporation formed under the laws of the State of California or its assigns (individually and collectively, " BioZone "), and ALCiS Health, Inc., a corporation formed under the laws of the California (" ALCiS "). Except as noted below, the License and Manufacturing Agreement ("Agreement"), dated August 17, 2005, between the parties shall remain in full force and effect. The Amendment dated September 28, 2005 between the parties shall have no further force or effect, and shall be replaced in its entirety by the Second Amendment dated December 27, 2005, which shall remain in full force and effect except as modified below.

NOW THEREFORE, in consideration of the representations and warranties, covenants and conditions set forth herein, and intending to be legally bound hereby, the parties hereto agree as follows: