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Re: Letter Agreement Regarding Durect Development and License Agreement

Loan Agreement

Re:     Letter Agreement Regarding Durect Development and License Agreement | Document Parties: ALPHARMA INC You are currently viewing:
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ALPHARMA INC

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Title: Re: Letter Agreement Regarding Durect Development and License Agreement
Date: 10/29/2008
Industry: Biotechnology and Drugs     Sector: Healthcare

Re:     Letter Agreement Regarding Durect Development and License Agreement, Parties: alpharma inc
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EXECUTION VERSION

October 7, 2008

Alpharma Inc.
Alpharma Operating Corporation
Alpharma U.S. Inc.
Barre Parent Corporation
Alpharma Euro Holdings Inc.
Alpharma (Bermuda) Inc.
Alpharma USHP Inc.
Alpharma Animal Health Company
Mikjan Corporation
Alpharma Holdings Inc.
Alpharma Specialty Pharma Inc.
Purepac Pharmaceutical Holdings, Inc.
Alpharma Pharmaceuticals LLC
440 Route 22 East
Bridgewater, New Jersey 08807

     Re:     Letter Agreement Regarding Durect Development and License Agreement

Ladies and Gentlemen:

     Reference is made to that certain Amended and Restated Loan and Security Agreement dated March 10, 2006 (as at any time amended, restated, supplemented or otherwise modified, the “Loan Agreement”), among Alpharma Inc., a Delaware corporation (“Parent”); Alpharma Operating Corporation, a Delaware corporation; Alpharma U.S. Inc., a Delaware corporation; Barre Parent Corporation, a Delaware corporation; Alpharma Euro Holdings Inc., a Delaware corporation; Alpharma (Bermuda) Inc., a Delaware corporation; Alpharma USHP Inc., a Delaware corporation; Alpharma Animal Health Company, a Texas corporation; Mikjan Corporation, an Arkansas corporation; Alpharma Holdings Inc., a Delaware corporation; Alpharma Specialty Pharma Inc., a Delaware corporation f/k/a Alpharma Pharmaceuticals Inc.; Purepac Pharmaceutical Holdings, Inc., a Delaware corporation; and Alpharma Pharmaceuticals LLC, a Delaware limited liability company f/k/a Alpharma Branded Products Division Inc. (collectively, “Borrowers” and each individually, a “Borrower”); the various financial institutions party thereto from time to time (collectively, “Lenders”); and Bank of America, N.A., a national banking association, in its capacity as collateral and administrative agent for Lenders (together with its successors in such capacity, “Agent”). Capitalized terms used herein and not otherwise defined herein shall have the meaning ascribed to such terms in the Loan Agreement.

     Borrowers have informed Agent and Lenders that Alpharma Ireland Limited, a corporation organized under the laws of Ireland (“Alpharma Ireland”), desires to effect a certain Development and License Agreement (the “License Agreement”) with Durect Corporation, a Delaware corporation (“Licensor”), pursuant to which Alpharma Ireland will license from Licensor certain proprietary products for pain treatment and certain patents and know-how relating thereto. In connection with the License Agreement, Licensor is requiring an unsecured guaranty from Parent with respect to all milestone payments of up to $263,000,000 in the aggregate and all royalty and other payments owing by Alpharma Ireland under the License Agreement (the “Parent Guaranty”). Borrowers have requested that Agent and

 


 

Lenders consent to the Parent Guaranty, and Agent and Lenders are willing to do so, on the terms and subject to the conditions contained herein.

     NOW THEREFORE, for Ten Dollars ($10.00) in hand paid, and other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto hereby agree as follows:

      1.  Consent . Subject to the satisfaction of the conditions precedent set forth below, Agent and Lenders hereby consent to the Parent Guaranty. Such consent is subject to the satisfaction of the following conditions precedent in form and substance satisfactory to Agent and Lenders in their sole and absolute discretion: (a) the Parent Guaranty and the License Agreement are executed and all conditions precedent to the effectiveness thereto are satisfied on or before December 31, 2008; (b) at the time of the execution of the Parent Guaranty and the License Agreement, and after giving effect thereto and hereto, no Default or Event of Default exists or would result therefrom; and (c) in connection with the execution of the License Agreement, Licensor and Alpharma Ireland have filed all documents that are required or permitted to be filed pursuant to the Hart-Scott-Rodino Antitrust Improvements Act of 1976 (as at any time amended, the “HSR”) and have received all necessary approval under the HSR in connection therewith.

      2.  Amendment to Loan Agreement . Upon satisfaction of the conditions precedent set forth above, the Loan Agreement shall be deemed amended as follows:

     (a) By deleting the definition of “Permitted Contingent Obligations” in Section 1.1 of the Loan Agreement and by substituting in lieu thereof the following:

      Permitted Contingent Obligations — each of the following:

(i) Contingent Obligations arising from endorsements of items of payment for collection or deposit in the Ordinary Course of Business;

(ii) Contingent Obligations of any Consolidated Group Member existing as of the Closing Date, including extensions and renewals thereof that do not increase the amount of such Contingent Obligations as of the date of such extension or renewal;

(iii) Contingent Obligations arising under indemnity agreements to title insurers to cause such title insurers to issue to Agent title insurance policies;

(iv) Contingent Obligations with respect to customary indemnification obligations in favor of purchasers in connection with dispositions of Equipment permitted under Section 8.4.2;

(v) Contingent Obligations consisting of reimbursement obligations from time to time owing by any Borrower to Issuing Bank with respect to Letters of Credit (but in no event to include reimbursement obligations at any time owing by a Borrower to any other Person that may issue letters of credit for the account of Borrowers);

(vi) unsecured guaranties made by a Consolidated Group Member for Debt or other obligations of another Consolidated Group Member that is expressly permitted to be incurred hereunder or not prohibited;

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(vii) Contingent Obligations of Parent arising under that certain unsecured guaranty dated September 4, 2007 (the “IDEA Guaranty”), from Parent to IDEA AG, a German corporation (“IDEA”), with respect to mi


 
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