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THIRD AMENDMENT TO THE MICHIGAN LICENSE AGREEMENT

License Agreement

THIRD AMENDMENT TO THE MICHIGAN LICENSE AGREEMENT | Document Parties: Cardium Biologics, Inc | Cardium Therapeutics, Inc | Matrigen, Inc | Prizm Pharmaceuticals, Inc | Selective Genetics, Inc | Tissue Repair Company You are currently viewing:
This License Agreement involves

Cardium Biologics, Inc | Cardium Therapeutics, Inc | Matrigen, Inc | Prizm Pharmaceuticals, Inc | Selective Genetics, Inc | Tissue Repair Company

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Title: THIRD AMENDMENT TO THE MICHIGAN LICENSE AGREEMENT
Date: 3/15/2007
Industry: Biotechnology and Drugs     Sector: Healthcare

THIRD AMENDMENT TO THE MICHIGAN LICENSE AGREEMENT, Parties: cardium biologics  inc , cardium therapeutics  inc , matrigen  inc , prizm pharmaceuticals  inc , selective genetics  inc , tissue repair company
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Exhibit 10.36

THIRD AMENDMENT TO LICENSE AGREEMENT

This Third Amendment to License Agreement ("Amendment"), dated 10 August 2006 ("Amendment Date"), is by and among Tissue Repair Company ("LICENSEE"), the Regents of the University of Michigan ("MICHIGAN") and Cardium Biologics, Inc. ("BUYER").

WHEREAS, Matrigen, Inc. ("Matrigen"), and MICHIGAN entered into a license agreement dated 13 July 1995; which license agreement was assigned by Matrigen, to Prizm Pharmaceuticals, Inc. ("Prizm") in March of 1998; after which Prizm changed its name to Selective Genetics, Inc. ("Selective Genetics"); and after which LICENSEE accepted all the rights and responsibilities of Selective Genetics under such license agreement as of 16 March 2005.

WHEREAS, the parties desire to modify certain provisions of such license agreement (as amended 10 August 1995, and 1 February 2004, "License Agreement") as provided herein.

WHEREAS, Matrigen and MICHIGAN entered into a roundtable research agreement dated 13 July 1995; which roundtable research agreement was assigned by Matrigen to Prizm Pharmaceuticals, Inc. ("Prizm") in March of 1998; after which Prizm changed its name to Selective Genetics, Inc. ("Selective Genetics"); after which such roundtable research agreement was amended in 12 February, 2004; after which LICENSEE accepted all the rights and responsibilities of Selective Genetics under such roundtable research agreement as of 16 March 2005; and after which such roundtable research agreement was terminated effective as of June 30, 2005.

WHEREAS, Cardium Therapeutics, Inc., BUYER and LICENSEE are entering into an Asset Purchase Agreement (the "Asset Purchase Agreement") pursuant to which BUYER will purchase from LICENSEE substantially all of the assets, properties, rights and claims of LICENSEE’s business including the License Agreement, on the terms and conditions of the Asset Purchase Agreement.

WHEREAS, the parties desire to confirm that the License Agreement is separate from the previously-terminated roundtable research agreement and that the License Agreement, as it is to be transferred to BUYER, is not intended to incorporate or impose upon BUYER any liabilities or obligations pursuant to the roundtable research agreement.

NOW THEREFORE, the parties hereby agree as follows:

1. Paragraph 2.3 shall be amended by deleting clause (b) in its entirety and replacing it with the following:

  • (b) was conceived or made solely as defined by U.S. Patent law by one or more employees of MICHIGAN in the performance of the Roundtable Research Agreement effective as of the 1st day of July 1995 (as amended, restated or extended from time to time), by and between MATRIGEN and MICHIGAN;

 

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2. With regard to Paragraph 4.5 of the License Agreement (which related solely to the roundtable research agreement), the License Agreement to be assumed by BUYER does not incorporate nor does it impose any liabilities or obligations with regard to the roundtable research agreement nor will the rights and interests of BUYER under this License Agreement be in any way subject to reduction, forfeiture or default due to any matters associated with the roundtable research agreement. Accordingly, Paragraph 4.5 of the License Agreement is deleted in its entirety.

3. Paragraph 7.6 shall be deleted in its entirely and replaced with the following:

  • Notwithstanding Paragraph 7.2, LICENSEE has completed a Phase I study fo


 
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