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Re:                                      Collaboration and License Agreement dated 15th August 2005

License Agreement

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IMCLONE SYSTEMS INC

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Title: Re:                                      Collaboration and License Agreement dated 15th August 2005
Governing Law: New York     Date: 3/1/2007
Industry: Biotechnology and Drugs     Sector: Healthcare

Re:                                      Collaboration and License Agreement dated 15th August 2005, Parties: imclone systems inc
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Exhibit 10.40

CONFIDENTIAL TREATMENT REQUESTED

[Note: Certain portions of this document have been marked to indicate that Confidential Treatment has been requested for such portions by ImClone Systems Incorporated. These portions have been marked with one asterisk enclosed in brackets (i.e. [*]). The confidential portions have been omitted and filed separately with the Securities and Exchange Commission.]

Letter Agreement

 

From:                                     ImClone Systems Incorporated
180 Varick Street
New York, NY 10014
USA

To:                                                 UCB Pharma S.A..
Allée de la Recherche
60 1070 Brussels
Belgium
Attn: General Counsel

 

Re:                                       Collaboration and License Agreement dated 15 th  August 2005
Among UCB, S.A. (“UCB”) and ImClone Systems Incorporated
(“ImClone”), and any and all amendments thereto (the “Agreement”)

Dear Sirs

All capitalised terms not otherwise defined herein shall have the meaning given such terms in the Agreement.  This letter agreement (the “Letter Agreement”) shall memorialise the settlement and compromise reached between UCB and ImClone (each a “Party”, and together the “Parties”) with respect to the Agreement.

WHEREAS , UCB and ImClone are parties to the Agreement;




 

WHEREAS , on 20th December 2006, the business of UCB S.A. was transferred to UCB Pharma S.A.  As a result of such transfer, the Agreement was assigned to UCB Pharma S.A.;

WHEREAS , ImClone desires to voluntarily terminate the Agreement at this time; and

WHEREAS , the Parties have agreed to settle and fully resolve UCB’s claims against ImClone for reimbursement of certain costs in connection with the Agreement.

 

NOW THEREFORE , in consideration of the mutual covenants and obligations set forth herein, and for other good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged, and intending to be bound hereby, the Parties agree as follows:

1.                                        When used in this Letter Agreement, the following terms shall have the meanings set out in this paragraph 1:

Dispute means the dispute between the Parties concerning the payment of, and their respective responsibility for, any and all costs under the Agreement, including development costs incurred prior to the Effective Date, Development Costs for Agreed Indications, Development Costs for Independent Indications, Manufacturing costs with respect to Antibody Products and the costs of Commercialisation of the Antibody Products.

2.                                        ImClone hereby gives UCB notice that it is terminating the Agreement under Article 12.2 thereof.  UCB acknowledges and agrees that such termination notice is valid, timely and binding upon UCB.  Upon termination, UCB shall be designated as the Remaining Party under Article 12 of the Agreement.

3.                                        Notwithstanding the terms of paragraph 2 above and subject to paragraph 4 below, the Parties agree that the articles of the Agreement listed in Article 12.11(b) of the Agreement shall survive termination of the Agreement.

4.                                        The Parties agree that the words “(with consent not to be unreasonably withheld or delayed)” shall be deleted from Article 12.8(c)(ii) of the Agreement.  UCB shall however provide written notice to ImClone of the identity of any such sublicense within five (5) business days of any such sublicense having been entered into pursuant to Article 12.8(c)(ii), together with confirmation that such sublicense contains all of the restrictions that apply to UCB, including without limitation those under Article 11 of the Agreement (Confidentiality and Non-Use).

5.                                        The Parties each acknowledge and agree that neither Party owes to the other Party any monetary consideration with respect to the Agreement nor any other amount relating to costs under the Agreement, including development costs incurred prior to the Effective




 
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