Exhibit 10.9
LICENSING AGREEMENT
NUTRACEUTICAL STANDARDS
THIS AGREEMENT
is made and entered into by and between The University of
Mississippi, an education and research institution chartered under
the laws of the State of Mississippi, with a principal address at
University, Mississippi 38677 (“UNIVERSITY”) and
ChromaDex, Inc. an incorporated company with a principal address at
8 Garzoni Aisle, Irvine California, 92606
(“CHROMADEX”).
RECITALS
1. UNIVERSITY leads a program of natural products discovery,
development and commercialization, and its National Center for
Natural Products Research is the nation’s only
university-based research center dedicated to an integrated program
of discovering, developing and commercializing new pharmaceuticals
and agrochemicals derived from natural sources.
2. UNIVERSITY has developed and owns rights to Know-how, data,
methods of analysis, trade secrets, technology, skill, and
experience relating to the scientific investigation, extraction,
purification of chemical constituents, analysis and development of
reference standards from a wide variety of natural product sources
which, to the extent not disclosed in issued patents, are
confidential and proprietary.
3. CHROMADEX is a company engaged in the development,
marketing and selling of reference standards for the Nutraceutical
market and the identification and isolation of the constituents
thereof and methodologies related thereto, and is interested in
obtaining from UNIVERSITY an exclusive license to the Technology
herein defined in the USA and foreign countries.
NOW,
THEREFORE, in consideration of the foregoing recitals and the
mutual covenants and agreements of the parties contained in this
Agreement, the parties agree as follows:
ARTICLE I
DEFINITIONS
As used in
this Agreement, the following terms will have those meanings set
forth in this Article unless the context dictates otherwise:
1.01 “
Effective Date of this Agreement ” means
December 31, 1999.
1.02 “
Technology ” means any and all information, and all
patentable and non-patentable inventions, discoveries,
improvements, claims, formulae, trade secrets, processes, methods,
data and Know-how developed, conceived, first reduced to practice
or demonstrated to have utility by or on behalf of UNIVERSITY on
the compounds specified in the Research Project as detailed in
Appendix A that relates to the extraction, isolation and
purification of chemical constituents for use as reference
standards and for the further purification or characterization of
reference standards acquired from other sources. “Methods
Technology” means all methods, processes and related data and
Know-how included in the Technology, and “Products
Technology” means all reference standards developed included
in the Technology. Excluded from Technology are any and all
information, and all patentable and non-patentable inventions,
discoveries, improvements, claims, formulae, trade secrets,
processes, methods, data and Know-how developed, conceived, first
reduced to practice or demonstrated to have utility by or on behalf
of UNIVERSITY on the compounds specified in the Research Project as
detailed in Appendix A that relates to the research and
development of new pharmaceutical or agrochemical ingredients or
products.
1.03 “
Affiliate ” means any corporation, company,
partnership, joint venture or other entity that controls, is
controlled by or is under common control with CHROMADEX. For the
purposes of this definition, “control” means the direct
or indirect ownership of at least fifty percent (50%), or such
lesser amount that is the maximum percentage allowed by applicable
law, of the shares entitled to vote or of the ownership
Interest.
1.04 “
Field of Use ” means the use of the Methods Technology
for the identification, isolation and purification of chemical
constituents for use as reference standards, and the
commercialization thereof; and the development, manufacture,
marketing and other commercialization of the Products
Technology.
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1.05 “
Territory ” means the entire world.
1.06 “
Reference Standard ” means any material sold for the
purposes of providing a material in a purified or semi-purified
form for use in analytical testing of materials from other
sources.
1.07 “
Licensed Standard ” means any Reference Standard or
part thereof originating directly from the conduct of the Research
Project as detailed in Appendix A that (a) uses in whole
or in part any information covered in the UNIVERSITY Know-how or
any issued, unexpired claim or pending claim contained in the
patent rights in the country in which any such standard or part
thereof is made, used or sold; or (b) is covered in whole or
in part or is manufactured using a process or is employed to
practice a process covered in the UNIVERSITY Know-how or any
issued, unexpired claim or pending claim contained in the Patent
Rights in the country in which any such Reference Standard or part
thereof is made, used or sold.
1.08 “
Gross Sales ” means the gross receipts from the sale
of Licensed Standards by CHROMADEX, and its Affiliates, less
allowances for:
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(a) |
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any cash, trade or quantity discounts; |
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(b) |
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sales taxes, duties or similar taxes or levies; |
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(c) |
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returns and replacements. |
Licensed Standards will be considered “sold” when
billed out or invoiced.
1.09 “
Net Profits ” shall be determined on a quarterly basis
as follows: Net Profits shall equal the gross revenues of CHROMADEX
for such fiscal quarter less all costs and expenses directly
associated with the generation of revenue; provided, however, that
depreciation and amortization shall not be a deduction, and capital
expenditures, debt service payments of principal and interest and
tax payments shall be deductions in calculating Net Profits for
such quarter.
1.10 “
Know-how ” means all existing information, materials
and devices, whether or not patented or patentable, pertaining to
the claims that describe the Technology and any related patent
rights that are owned or controlled by UNIVERSITY or its affiliates
as of the date of this Agreement and all of the above developed by
UNIVERSITY and delivered by UNIVERSITY to CHROMADEX during the term
of the Research Project funded by CHROMADEX as detailed in
Appendix A.
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1.11 “
UNIVERSITY Personnel ” means any University of
Mississippi employee, student, or independent contractor, including
any consultant under obligation of confidentiality to
UNIVERSITY.
1.12 “
CHROMADEX Personnel ” means any CHROMADEX employee or
independent contractor, including any consultant under obligation
of confidentiality to CHROMADEX.
1.13 “
Research Project ” means the project conducted by
UNIVERSITY under a grant from CHROMADEX as detailed in
Appendix A to develop specific botanical reference standards
that is incorporated herein by reference. The Research Project may
be amended by mutual agreement in writing by both parties. An
amendment to the Research Project will be attached as an amendment
to this Agreement unless the scope of the Research Project has
changed such that either party requests a separate licensing
agreement to cover the intellectual property that may result from
the amended research plan.
1.14 “
Licensing Income ” means payments made by CHROMADEX to
UNIVERSITY in consideration of the license rights granted by
UNIVERSITY to CHROMADEX to make, have made, use and sell Licensed
Standards and Technology.
ARTICLE II
LICENSE
2.1
Grant . UNIVERSITY grants to CHROMADEX the exclusive right
and license to Technology originating from the Research Project in
the Territory for the Field of Use, and to the extent not
prohibited by patents owned by third parties to make, have made,
use and sell Licensed Standards and Technology until the end of the
Term of this Agreement (as hereinafter defined) unless
CHROMADEX’s rights under this Agreement are sooner terminated
according to the terms hereof.
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2.2
Reservation . UNIVERSITY reserves the right to practice
Methods Technology and utilize Products Technology and Know-how for
research and product development purposes outside the Field of Use,
UNIVERSITY reserves the right to practice Methods Technology and
utilize Products Technology and Know-how for its own research
purposes.
2.3
Sublicenses . CHROMADEX will have the right to enter into
sublicensing agreements for the rights, privileges and licenses
granted hereunder during the Term of this Agreement subject to
advanced written consent of the UNIVERSITY. Such written consent
will not be unreasonably withheld or delayed. CHROMADEX agrees that
any sublicenses granted by it will provide that the obligations to
UNIVERSITY including Articles 4, 5, 6, 7, 8 and, 9 of this
Agreement will be binding upon the Sublicensee as if it were a
party to this Agreement. CHROMADEX agrees to forward to UNIVERSITY
a full and complete copy of any and all sublicense agreements
within ten (10) days of execution by the parties, which
UNIVERSITY will treat as Confidential Information. Upon any
termination of this Agreement, rights of any sublicensees will also
terminate, subject to Paragraph 6.5 hereof.
2.4 Equity
Position . CHROMADEX grants UNIVERSITY a two percent (2%)
equity position in CHROMADEX based on the capitalization of
CHROMADEX as of the date hereof, as set forth in Appendix B which
is incorporated herein by reference. In any transaction under which
CHROMADEX’ capital stock is issued, CHROMADEX shall issue
additional shares to UNIVERSITY at no cost, such that
UNIVERSITY’s capital stock shall be undiluted until CHROMADEX
has issued capital stock at a valuation of at least four million
dollars ($4,000,000), but in any case UNIVERSITY’s capital
stock shall not be treated in a manner less favorable than the
capital stock of the founders. UNIVERSITY will accomplish vesting
in the equity position by the completion of the specific milestone
activities agreed to by both parties as defined in Appendix B,
which is incorporated herein by reference. Should UNIVERSITY be
unable to complete the milestones stipulated in Appendix B due
to the lack of availability of, or delay in providing the raw
materials that are to be supplied by CHROMADEX, then the parties
will negotiate in good faith a modification of the milestone
deadlines, which they will then agree to in writing.
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2.5
Licensing Income . In addition to the Equity Position
stipulated in Paragraph 2.4 hereof, CHROMADEX will pay UNIVERSITY
on a quarterly basis twenty-five (25) percent of the Net
Profits of the company, including revenue generated by CHROMADEX
from business activities outside the sale of Licensed Standards and
Technology, or two (2) percent of the Gross Sales of the
Licensed Standards and Technology whichever is greater, not to
exceed a total annual payment of $325,000 per 12-month period until
the total of such payments equals $487,500 and thereafter two
(2) percent of the Gross Sales of the Licensed Standards. In
addition to the two (2) percent payment referred to above on
CHROMADEX’ Gross Sales, UNIVERSITY will be entitled to
receive a “pass through royalty” (the “Pass
Through Royalty”) of twenty (20) percent of all license fees,
milestone payments, maintenance fees, and royalties received by
CHROMADEX from sublicensees, but not in excess of two
(2) percent of such sublicensees’ Gross Sales, and
specifically excluding any payment to UNIVERSITY with regard to
consideration received by CHROMADEX for research and development
activities or the acquisition of securities of CHROMADEX. Payments
will be paid by CHROMADEX within forty-five (45) days of the
close of each quarter to The University of Mississippi, University,
Mississippi 38677 or at such other places as UNIVERSITY may
reasonably designate.
ARTICLE III
TECHNOLOGY TRANSFER, PUBLICATIONS AND
INVENTIONS
3.0
Cooperation . UNIVERSITY agrees to provide assistance to
CHROMADEX in the transfer of the methods, of preparing and
analyzing the Licensed Standards and in presenting technical data
at conferences and trade shows. The UNIVERSITY agrees to make
Dr. Ikhlas Khan of UNIVERSITY available to CHROMADEX under the
terms of a separate consulting agreement to be negotiated in good
faith by both parties. Termination of the consulting agreement or
Dr. Khan’s departure from UNIVERSITY is not a breach of
this Agreement as described in Section 6.1.
3.1
Publications . UNIVERSITY will be free to publish or present
any data generated on the Technology prior to the signing of this
agreement. Both parties recognize that either party may wish to
publish the results of its work under this Agreement. However, both
parties recognize the importance of acquiring patent protection on
inventions. Consequently, any proposed publication arising from
work conducted under this Agreement by UNIVERSITY or CHROMADEX
Personnel will comply with this section. At least thirty
(30) days before a manuscript is to be submitted to a
publisher, UNIVERSITY or CHROMADEX Personnel will provide the other
party with a copy of the manuscript.
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If
UNIVERSITY or CHROMADEX Personnel wish to make an oral
presentation, they will provide the other party with a copy of the
abstract (if one is submitted) at least thirty (30) days
before it is submitted. UNIVERSITY or CHROMADEX Personnel will also
provide the other party with a copy of the text of the
presentation, including all slides, posters, and any other visual
aids, at least thirty (30) days before the presentation is
made. CHROMADEX or UNIVERSITY will review the manuscript, abstract,
or text to determine if patentable subject matter is disclosed.
CHROMADEX or UNIVERSITY will notify the party that desires to
publish within twenty-one (21) days of receipt of the proposed
Publication if they determine that patentable subject matter is or
may be disclosed, or if they believe confidential or proprietary
information is or may be disclosed. If it is determined by
CHROMADEX or UNIVERSITY that patent applications should be field,
UNIVERSITY or CHROMADEX Personnel will delay its publication or
presentation for a period not to exceed ninety (90) days from
CHROMADEX’s or UNIVERSITY’s receipt of the proposed
Publication to allow time for the filing of patent applications
covering patentable subject matter. In the event that the delay
needed to complete the filing of any necessary patent application
will exceed the ninety (90) day period, UNIVERSITY or
CHROMADEX Personnel will discuss with the party that desires to
publish the need for obtaining an extension of the publication
delay beyond the ninety (90) day period. The publication delay
will not exceed 120 days from the date that the proposed
publication was first submitted to CHROMADEX or UNIVERSITY for
review, except that, by mutual agreement, as provided in this
Section, this delay may be extended past the 120 day period
for purposes of filing patent applications. If it is determined by
CHROMADEX and UNIVERSITY that confidential or proprietary
information is being disclosed, the parties will consult among
themselves in good faith to arrive at agreement on mutually
acceptable modifications to the proposed publication to avoid such
disclosure.
3.2
Ownership of Inventions . It is recognized that inventions
may be developed, conceived, first reduced to practice or
demonstrated to have utility during the conduct of or arising from
or resulting from the work conducted under the Research Plan. As a
guide to allocation of ownership of such inventions, whether
patentable or unpatentable, the parties agree that:
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(a) |
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Inventions made solely by employees of CHROMADEX
(“CHROMADEX Inventions”) shall be owned by
CHROMADEX. |
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(b) |
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Inventions made solely by employees of UNIVERSITY
(“University Inventions”) shall be owned by UNIVERSITY;
and |
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(c) |
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Inventions made jointly by UNIVERSITY personnel and CHROMADEX
personnel (“Joint Inventions”) will be jointly owned by
UNIVERSITY and CHROMADEX. All UNIVERSITY Inventions and Joint
Inventions shall constitute Technology hereunder licensed
exclusively to CHROMADEX in accordance with the terms of this
Agreement |
ARTICLE IV
CONFIDENTIALITY
4.0
Confidentiality; Exceptions . Except to the extent expressly
authorized by this Agreement or as otherwise agreed to in writing,
UNIVERSITY and CHROMADEX agree that any technical information, data
and Materials which they exchange in connection with this Agreement
will be treated as Confidential Information, and that each party
will not use such Confidential Information for its own purposes
except as permitted hereunder, nor disclose it to others, except to
the extent that it can be established by the receiving party by
competent proof that such Confidential Information:
(a) was a
part of the public domain at the time of its disclosure to the
receiving party; or
(b) became a part of the public domain after its disclosure to
the receiving party, but not due to some unauthorized act by or
omission of such party; or
(c) was
already known to the receiving party, other than under an
obligation of confidentiality at the time of disclosure by the
other party, as evidenced by its written records; or
(d) was
disclosed to the receiving party, other than under an obligat
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