Exhibit 2.4
LICENSE
AGREEMENT
THIS LICENSE
AGREEMENT (the “Agreement”) is made as of the _____ day
of April, 2007, by and between BioVeris Corporation
(“BioVeris”), a Delaware corporation having a principal
place of business at 16020 Industrial Drive, Gaithersburg, Maryland
20877, United States of America, and 32 Mott Street Acquisition II,
LLC (“Newco”), a Delaware limited liability company
having offices at __________________________________, with
reference to the following facts:
WHEREAS, BioVeris
has conducted research on, has developed and owns rights to certain
technology and products with respect to, among other things, the
detection and/or quantification of compounds for diagnostic
procedures based on electrochemiluminescent compounds;
and
WHEREAS, BioVeris
and Newco are willing to enter into a non-exclusive license, as is
set forth in this Agreement;
NOW, THEREFORE,
in consideration of the foregoing and the mutual covenants and
promises set forth below, Newco and BioVeris (the
“Parties”) hereby agree as follows:
1.
Definitions
. As used in this
Agreement, capitalized terms shall have the respective meanings set
forth below:
1.1.
Affiliate . “Affiliate” of any person means
another person that directly or indirectly, through one or more
intermediaries, controls, is controlled by, or is under common
control with, such first person. The term “person”
means any individual, firm, corporation, partnership, company,
limited liability company, trust, joint venture, association,
Government Entity or other entity. The term “control”
means direct or indirect ownership of more than fifty percent (50%)
of the voting interest in a corporation or entity, or such other
relationship as, in fact, constitutes actual control of the
management or policies of a corporation or other entity or the
ability to cause the direction of the management or policies of a
corporation or other entity. The term “Government
Entity” means any domestic or foreign (whether a national,
Federal, state, provincial, local or otherwise) government or any
court of competent jurisdiction, agency or commission or other
governmental authority or instrumentality, domestic or foreign.
Neither Genentech Inc., 1 DNA Way, South San Francisco, California
94080-4990, USA nor Chugai Pharmaceutical Co., Ltd, 1-9 Kyobashi
2-chome, Chuo-ku, Tokyo, 104-8301, Japan shall be deemed an
Affiliate of BioVeris for purposes of this Agreement. Neither Meso
Scale Diagnostics, LLC., 9238 Gaither Road, Gaithersburg, Maryland,
USA 20877 (“MSD”) nor Meso Scale Technologies, LLC.,
9238 Gaither Road, Gaithersburg, Maryland, USA 20877
(“MST”) shall be deemed an Affiliate of BioVeris or
Newco for purposes of this Agreement.
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1.2.
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ECL Patent
Rights . “ECL Patent
Rights” means:
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(a) All
patents, patent applications and patent rights listed in Exhibit A
hereto; and
(b) Any
other patents or patent applications that claim priority to one or
more of the patents and patent applications listed in Exhibit A
including corresponding foreign applications or patents; any
patents or patent applications that claim priority to a priority
application of one or more of the patents and patent applications
listed in Exhibit A including corresponding foreign applications or
patents; and
(c) Any
substitutions, divisions, continuations, continuations in part,
renewals, reissues, confirmations or registrations of the patents,
patent applications and patent rights under Sections 1.2(a) and (b)
above and extensions of the foregoing, now existing or hereafter
filed.
1.3.
ECL Instrument . “ECL Instrument” means an
instrument manufactured by or for Newco that uses or is based upon
ECL Technology so long as such instrument (i) weighs 40 kg or less;
(ii) has a physical size of 125,000 cubic centimeters (measured by
integrating the total volume encompassed by the entire instrument)
or less; and (iii) has an actual footprint of 2,500 square
centimeters or less; in each case not including peripherals such as
printers, display screens, sample preparation equipment, IT
equipment, software or the like.
1.4.
ECL Product(s) . “ECL Product(s)” means any ECL
Instrument or assay, reagent, chemical, consumable, test, nucleic
acid probe, biological or other substance useable on an ECL
Instrument that would directly or indirectly infringe a valid claim
of any of the ECL Patent Rights and/or make use of any of the
Licensed ECL Technology, and service for ECL
Instruments.
1.5.
ECL Technology . “ECL Technology” means
detection methods and detection systems, which employ
electrochemiluminescence in detection and/or quantification by
which light generation occurs when a molecular compound (such as a
ruthenium metal chelate) emits electromagnetic radiation, including
photons, and shall also include but not be limited to ECL reagents,
ECL assays and/or ECL diagnostic detection methods.
1.6.
Improvements . “Improvements” means any and all
inventions, discoveries and improvements related to ECL Technology
(whether or not patentable) developed, created, conceived or
reduced to practice by a person or entity.
1.7.
Licensed ECL Technology . “Licensed ECL
Technology” means (1) the ECL Patent Rights and (2) any and
all proprietary or confidential or technical information relating
to ECL Technology owned by BioVeris as of the Effective Time,
including, but not limited to techniques, including data reduction
methods or techniques, methods for using, storing, retrieving,
disseminating, archiving, distributing or carrying out information
or analysis, designs, specifications, test results, instruments,
compounds, devices, ideas, technical information, processes,
including signal
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processing,
schematics, inventions, discoveries, methods, know-how, show-how,
hardware, firmware and software (including object codes and source
codes) whether or not based on ECL Patent Rights, whether or not
the same is eligible for protection under the patent laws of the
United States or elsewhere, and whether or not any such processes
and technology, or information related thereto, would be
enforceable as a trade secret or the copying of which would be
enjoined or restrained by a court as constituting unfair
competition. “Licensed ECL Technology” shall include
without limitation, the inventions in the ECL Patent Rights.
”Licensed ECL Technology” includes technology related
to gene amplification or Nucleic Acid Probes or methods using
Nucleic Acid Probes.
1.8.
Non-Exclusive . “Non-Exclusive” as to the grant
of a license right means that the licensor may during the Term of
this Agreement exercise the licensed rights itself or grant
non-exclusive licenses to a third party, or retain for itself any
non-exclusive license rights.
1.9.
Nucleic Acid Probe . “Nucleic Acid Probe” shall
mean one or more compounds that is/are: (y) composed of
one or more nucleotides or analogs thereof; or (z) capable of
binding with one or more nucleotides or analogs thereof.
1.10.
Term . The “Term” of this Agreement shall mean
the entire period of time this Agreement is in full force and
effect and shall begin at the Effective Time and terminate
automatically upon the later of (a) the expiration of the
last-to-expire of the patents included in the ECL Patent Rights
that is not earlier invalidated, or its enforcement enjoined, by a
final decision of a court of competent jurisdiction from which no
further appeal may be taken or (b) complete loss of confidential
and proprietary status for all of the Licensed ECL Technology. The
term “Effective Time” shall have the meaning ascribed
to that term in Merger Agreement of even date herewith by and
between, inter alia, BioVeris and Roche Holding Ltd (the
“Merger Agreement”).
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2.
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Grant and Scope
of Licenses .
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2.1.
License Grant . During the Term of this Agreement, and
subject to the terms and conditions of this Agreement, and the
rights of MSD, MST or Jacob Wohlstadter under all pre-existing
agreements, without any further amendments or changes after the
Effective Time that would restrict, impair, cutback or reduce the
rights otherwise being conferred by this Agreement, between
BioVeris or IGEN International Inc. (“IGEN”) and MSD
and/or MST, including without limitation the IGEN/MSD License
Agreement entered between MSD and IGEN on November 30, 1995, and
amended on August 15, 2001 and August 12, 2004 (collectively, the
“MSD/MST Agreements”), BioVeris grants to Newco, for
use in any and all fields, an irrevocable, perpetual,
Non-Exclusive, worldwide, fully-paid, royalty-free right and
license under the Licensed ECL Technology, solely for use on or
incorporated in an ECL Instrument, to research, have researched,
develop, have developed, prepare derivative works based on,
reproduce, use, have used, manufacture, have manufactured,
distribute, have distributed, display, perform, modify, import,
have imported, sell, offer for sale, have sold, export, have
exported, service, have serviced, lease and otherwise commercially
exploit ECL
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Products. The
fields covered by the foregoing license shall include human in
vitro diagnostic testing, life science research and/or development
(including at any pharmaceutical company or biotechnology company),
drug discovery and/or drug development (including at any
pharmaceutical company or biotechnology company), including
clinical research or determinations in or for clinical trials or in
the regulatory approval process for a drug or therapy, veterinary,
food, water or environmental testing or use and all other fields in
which ECL Products may be commercialized by Newco prior to or
following the Effective Time.
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2.2.
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Included
(Excluded) Rights .
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(a) The
rights and licenses granted in Section 2.1 hereof include the right
of Newco to grant to its distributors, sales representatives,
contract manufacturers, toll manufacturers, component suppliers,
leasing agents and other third parties, including Affiliates,
engaged by Newco hereunder to assist Newco in commercializing the
intellectual property rights licensed to Newco hereunder (the
“Authorized Third Parties”) immunity from suit under
the Licensed ECL Technology for activities conducted in connection
with such purposes or services solely for the benefit of Newco, and
further includes the right of Newco to grant immunity from suit
under the Licensed ECL Technology to Newco’s direct or
indirect customers (including OEM customers) or any other end-user
for use or subsequent sale of those ECL Products in any field. No
person, or any member of an Affiliated group of persons shall
become an Authorized Third Party if at the time they would become
an Authorized Third Party they are designated as a Major Health
Care Technology Company pursuant to Section 5.3 hereof; provided
however, that no Authorized Third Party shall lose its
qualification or status as an Authorized Third Party, and no
contract, arrangement, commitment or understanding, including any
extensions, renewals, modifications, or amendments thereof, between
Newco and such Authorized Third Party shall be voidable, impaired,
restricted, terminated or otherwise affected or compromised because
such Authorized Third Party is designated pursuant to Section 5.3
hereof as a Major Health Care Technology Company at any time after
first becoming an Authorized Third Party, provided that the
services of such Authorized Third Party shall be limited to those
services which are the subject of a binding contract with such
Authorized Third Party at the time it is designated as a Major
Health Care Technology Company. From and after the point in time,
if any, but only after giving effect to all extensions, renewals,
modifications and amendments, that an Authorized Third Party no
longer serves in such capacity, such person shall thereupon become
subject to the restrictions of this Section 2.2(a) regarding Major
Health Care Technology Companies. Notwithstanding the above, any
Affiliate of Newco which becomes an Authorized Third Party shall
lose its status as an Authorized Third Party, and shall not provide
any further services as an Authorized Third Party, upon becoming an
Affiliate of a Major Health Care
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Technology Company
and may not in any event transfer its rights as an Authorized Third
Party to any Major Health Care Technology Company. Furthermore,
Authorized Third Parties shall have such rights to use the Licensed
ECL Technology licensed to Newco hereunder in all fields as may be
necessary to allow such Authorized Third Parties to assist Newco in
the commercialization of Licensed ECL Technology; provided,
however, that the exercise of such licensed rights by such
Authorized Third Parties shall not constitute a sublicense or
assignment by Newco hereunder. Newco shall: (i) assure
that the Authorized Third Parties’ use of the Licensed ECL
Technology licensed hereunder to Newco is utilized by such
Authorized Third Parties for the exclusive benefit of Newco and in
compliance with this Agreement; and (ii) cause each Authorized
Third Party to assign to Newco any and all Improvements which such
Authorized Third Party may develop, create, conceive or reduce to
practice. Newco shall indemnify BioVeris and its Affiliates (and
their respective officers, directors, shareholders,
representatives, employees, consultants and agents and each of the
heirs, executors, successors and assigns of the foregoing) against
any loss, cost, damage or liability (including reasonable
attorneys’ fees) arising from Newco’s failure to
perform its obligations under the preceding sentence. In addition,
any Authorized Third Party which does not comply with (ii) above
shall not benefit from the immunity from suit described in this
Section if such Authorized Third Party sues BioVeris or any of its
Affiliates or sublicensees to the extent such suit by such
Authorized Third Party is based on those intellectual property
rights which should have been assigned to Newco in accordance with
(ii) above.
(b) Newco
shall have no right to develop, use, manufacture, have manufactured
or sell ECL assays that are packaged specifically for, and function
only for use on, instruments manufactured or sold by BioVeris or
its licensees (other than Newco), resellers or Affiliates, except
that Newco may use any such ECL assays that it manufacturers or has
manufactured, or commercially available products that it purchases
from third parties, whether or not such third parties are
Authorized Third Parties, on instruments that Newco owns and uses
in its internal research and development program for ECL
Instruments.
(c) No
rights are licensed or deemed licensed to Newco hereunder or in
connection herewith, other than those rights expressly licensed to
Newco in Sections 2.l and 2.2.
2.3.
Newco Technology . Nothing contained in this Agreement shall
be construed to limit or restrict, in any way or manner, any right
of Newco or its Affiliates to use, license, transfer or sell its
owned or licensed intellectual property rights from third parties
(excluding the rights licensed to Newco hereunder) anywhere in the
world and/or for any purpose.
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2.4.
Sublicenses . Newco shall have no right to grant sublicenses
to the licenses granted in Article 2 hereof to any third parties,
including Newco’s Affiliates.
2.5.
Consideration . The consideration for the license grants and
other rights provided to Newco under this Agreement is hereby
agreed to be 90% of the Purchase Price (as such term is defined in
the ECL Asset Transfer Agreement, dated as of April 4, 2007, by and
among BioVeris and Newco (the “ECL Asset Transfer
Agreement”)), which Purchase Price will be paid pursuant to
the terms of the ECL Asset Transfer Agreement.
3.
Licensor Retains Ownership . Newco acknowledges and agrees
that Newco has no rights in or to the intellectual property rights
licensed to Newco, other than the license rights specifically
granted herein. Nothing in this Agreement shall obligate BioVeris
or its Affiliates to obtain ownership of or sublicensing rights to
intellectual property rights obtained from or licensed from third
parties.
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4.
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Dispute
Resolution; Venue And Choice Of Law .
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4.1.
Good Faith Resolution . In the event that at any time during
the Term of this Agreement a disagreement, dispute, controversy or
claim should arise out of or relating to the interpretation of this
Agreement, or performance by a Party under this Agreement, or a
breach of this Agreement by a Party, or any claim by a Party that
any provision of this Agreement is invalid (a “Dispute”
or collectively “Disputes”) , one Party shall give
written notice to the other Party that a Dispute exists and the
Parties will then attempt in good faith to resolve their
differences before resorting to arbitration as provided in Section
4.2. If the Parties cannot resolve the Dispute within thirty (30)
days after such notice, then either Party shall be free to submit
the Dispute to binding arbitration in accordance with Section 4.2
hereof. For purposes of this Article 4, the terms
“Party” and “Parties” shall include each of
the signatories to this Agreement and/or any one or more of their
respective Affiliates, whether the reference is to a Party as a
claimant or a Party against which a claim is made.
(a) The
Parties intend Section 4.2 hereof to be enforceable in accordance
with the Federal Arbitration Act (9 U.S.C. Section 1, et seq.),
including any amendments to that Act which are subsequently
adopted, notwithstanding any other choice of law provision set
forth in this Agreement. In the event that either Party refuses to
submit to arbitration as required herein, the other Party may
request a United States District Court to compel arbitration in
accordance with the Federal Arbitration Act.
(b) Any
Dispute or other matter in question between Newco and BioVeris
arising out of or relating to the formation, interpretation,
performance, or breach of this Agreement, whether such dispute or
matter arises before or after termination of this Agreement, shall
be resolved solely by arbitration if the Parties are unable to
resolve the dispute through
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negotiation
pursuant to Section 4.1 hereof. Arbitration shall be initiated by
the delivery of a written notice of demand for arbitration by one
Party to the other. The date on which the other Party receives such
written notice shall be hereinafter referred to as the
“Arbitration Notice Date.”
(c) Each
Party shall appoint an individual as arbitrator and the two so
appointed shall then appoint a third arbitrator. If either Party
refuses or neglects to appoint an arbitrator within thirty (30)
days after the Arbitration Notice Date, then the arbitration shall
be conducted by a single arbitrator appointed by the American
Arbitration Association. If two arbitrators are appointed but do
not agree on the third arbitrator within sixty (60) days after the
Arbitration Notice Date, each of the arbitrators shall nominate
within sixty-seven (67) days after the Arbitration Notice Date
three individuals. Each arbitrator shall then within seventy-two
(72) days after the Arbitration Notice Date decline two of the
nominations presented by the other arbitrator. The third arbitrator
shall then be chosen from the remaining two nominations by drawing
lots. Notwithstanding anything contained herein to the contrary, if
the third arbitrator is not chosen with seventy-two (72) days after
the Arbitration Notice Date, then the American Arbitration
Association shall appoint the third arbitrator within seventy-seven
(77) days after the Arbitration Notice Date. The arbitrators shall
not be or have been affiliated with, or have any personal,
financial or business relationship with, either of the Parties or
any Affiliate of either Party; the arbitrators shall not have a
personal or financial interest in the result of the
arbitration.
(d) The
arbitration hearings shall be held in Borough of Manhattan, State
of New York or such other place as may be mutually agreed by the
Parties, shall be conducted in the English language and shall be
conducted as confidential proceedings (except to the extent
necessary to enforce the award resulting therefrom). Unless the
Parties agree otherwise, the arbitrators shall commence the
arbitration hearing within thirty (30) days after the selection of
the third arbitrator. The arbitrators shall issue orders to protect
the confidentiality of proprietary information, trade secrets and
other sensitive information disclosed. Pending the arbitration
hearing, at the request of a Party, the arbitrators may issue
temporary injunctive or other equitable relief to address any
violation or threatened violation of this Agreement. The
arbitration hearings shall be completed within a reasonable number
of sessions as determined by the arbitrators. All awards shall be
made based on a majority vote of the arbitrators, shall be in
writing, shall not be considered confidential information of either
Party, shall be issued within sixty (60) days after hearings before
the arbitrators are completed, and shall state the reasoning on
which the award rests unless the Parties agree otherwise. In
addition to any relief at law which may be available to an
aggrieved Party for such breach, such Party shall be entitled to
injunctive and other equitable relief as the arbitration panel may
grant. The
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arbitrators shall
deliver a copy of the award to each Party personally or by
registered mail. Any party may request within ten (10) days after
receiving the decision that, for good cause, the arbitrators
reconsider and modify such decision. The arbitrators shall have
thirty (30) days after such request to modify their decision, if
they consider it appropriate. Thereafter, the decision of the
arbitrators shall be final, binding and nonappealable, except to
the extent appeals are permitted by the Federal Arbitration Act,
with respect to all persons, including (without limitation) persons
who have failed or refused to participate in the arbitration
process. Judgment upon the award rendered may be entered in any
court having jurisdiction thereof.
(e) Each
Party shall bear its own costs in connection with any such
arbitration including, without limitation, (i) all legal,
accounting, and any other professional fees and expenses, (ii) the
fees and expenses of its own arbitrator, and (iii) all other costs
and expenses each Party incurs to prepare for such arbitration.
Other than set forth above, each side shall pay, (iv) one-half of
the fee and expenses of the third arbitrator, and (v) one-half of
the other expenses that the Parties jointly incur directly related
to the arbitration proceeding.
(f) Except
as provided above, arbitration shall be based upon the Commercial
Arbitration Rules of the American Arbitration Association.
Discovery shall be limited at the discretion of the arbitrators, so
that the timing and extent of such discovery shall not interfere
with the normal business operations of the Parties. The arbitrators
may proceed to an award notwithstanding the failure of either Party
to participate in the proceedings.
(g) In
the event of subsequent actions or proceedings to confirm the award
or to enforce the judgment entered thereon or any other rights
flowing therefrom, the prevailing Party shall be entitled to
recover its reasonable attorney’s fees incurred in such
actions or proceedings.
(h) The
fact that the dispute resolution procedures specified in this
Article 4 shall have been or may be invoked shall not excuse any
Party from performing its obligations under this Agreement, and
during