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THIRD AMENDMENT TO LEASE

Lease Agreement

THIRD AMENDMENT TO LEASE | Document Parties: MDRNA, INC. | BMR-3450 MONTE VILLA PARKWAY LLC | Nastech Pharmaceutical Company Inc | Phase 3 Science Center LLC You are currently viewing:
This Lease Agreement involves

MDRNA, INC. | BMR-3450 MONTE VILLA PARKWAY LLC | Nastech Pharmaceutical Company Inc | Phase 3 Science Center LLC

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Title: THIRD AMENDMENT TO LEASE
Governing Law: California     Date: 3/10/2009
Industry: Biotechnology and Drugs     Sector: Healthcare

THIRD AMENDMENT TO LEASE, Parties: mdrna  inc. , bmr-3450 monte villa parkway llc , nastech pharmaceutical company inc , phase 3 science center llc
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Exhibit 10.1

THIRD AMENDMENT TO LEASE

THIS THIRD AMENDMENT TO LEASE (this “ Amendment ”) is entered into as of this 5 th day of March, 2009, by and between BMR-3450 MONTE VILLA PARKWAY LLC, a Delaware limited liability company (“ Landlord ,” as successor-in-interest to Phase 3 Science Center LLC (“ Original Landlord ”)), and MDRNA, INC., a Delaware corporation (“ Tenant ,” as successor-in-interest to Nastech Pharmaceutical Company Inc. (“ Original Tenant ”)).

RECITALS

A. WHEREAS, Original Landlord and Original Tenant entered into that certain Lease dated as of April 23, 2002, as amended by that certain First Amendment to Lease dated as of July 1, 2003, and that certain Second Amendment to Lease dated as of January 29, 2004 (collectively, the “ Lease ”), whereby Tenant leases certain premises (the “ Premises ”) from Landlord at 3450 Monte Villa Parkway in Bothell, Washington (the “ Building ”);

B. WHEREAS, Tenant intends to vacate the Premises prior to the expiration of the term of the Lease and has requested rent, operating expense and maintenance payment relief and that Landlord assume certain maintenance obligations at the Building;

C. WHEREAS, Tenant is in default of Tenant’s obligation to pay Rent and replenish the Security Deposit as set forth in the Lease; and

D. WHEREAS, Landlord and Tenant desire to modify and amend the Lease only in the respects and on the conditions hereinafter stated.

AGREEMENT

NOW, THEREFORE, Landlord and Tenant, in consideration of the mutual promises contained herein and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, and intending to be legally bound, agree as follows:

1.  Definitions . For purposes of this Amendment, capitalized terms shall have the meanings ascribed to them in the Lease unless otherwise defined herein.

2.  Maintenance Obligations . Notwithstanding anything in the Lease to the contrary, Landlord hereby agrees to (a) maintain and repair the roof; the exterior of the Building; the landscaping; the parking lot; the elevators; and the Building’s HVAC, electrical, plumbing, security, exterior generator, fire sprinkler (including related alarms) systems, and other building systems including the DI water system, air compressors, vacuum pumps and nitrogen (b) wash the outside windows of the Building, (c) supply regular janitorial service, including refuse removal, (d) maintain 3 small and 1 large Millipore water systems, 2 large glass washers, approximately 60 small “R&D” cubicles, approximately 40 standard size cubicles, approximately 20 sets of furniture for private offices and an autoclave (e) supply the following utilities: phones for the elevators and alarms, water, sewer, gas and electricity (collectively, the “ Maintenance Obligations ”), the cost of which shall be paid by Tenant as Additional Rent, except as abated in Section 6 below. The parties acknowledge that the building systems and other items within the Premises referenced in this Section 2 are attached to and have become an integral part of the Premises and shall not be considered Tenant’s Removable Property or otherwise allowed to be removed by Tenant.

3.  Entry into Premises . Landlord’s right to enter the Premises as set forth in Section 32.2 of the Lease shall be expanded to permit Landlord to perform the Maintenance Obligations and for Landlord and Landlord’s agents to show the Premises to any potential tenant, purchaser, affiliate or lender.

4.  Basic Annual Rent and Operating Expenses . Concurrently with the execution and delivery of this Amendment, Tenant shall pay Landlord funds that total $205,943.51 (“ Cure Amount ”), which amount shall be applied to Basic Annual Rent and Tenant’s Pro Rata Share of Operating Expenses (including late fees) in default for the month of January 2009 and to replenish the Cash Deposit to the amount required under the Lease (i.e., $277,140). From and after Tenant’s delivery of the Cure Amount, Landlord shall no longer be required to keep the Cash Deposit in a separate account bearing interest for the benefit of Tenant. Landlord may intermingle the Cash Deposit with Landlord’s general funds and Tenant shall not be entitled to any interest accruing on the Cash Deposit.

5.  Cash Deposit and Letter of Credit . Notwithstanding anything to the contrary in the Lease, Landlord may on the first day of each month commencing on March 1, 2009, draw upon the Cash Deposit or Letter of Credit to cover payments of Rent without the need for notice to Tenant or affording Tenant an opportunity to cure. In addition, Landlord shall remain entitled to draw on the Security Deposit for any other purpose set forth in the Lease or this Amendment. Tenant shall cooperate with Landlord and shall sign any necessary documents requested by the lender issuing the Letter of Credit to assist in Landlord drawing upon the Letter of Credit in accordance with the Lease or this Section 4 . Following payment of the Cure Amount, there shall be no obligation now or at any time in the future by Tenant to replenish or renew the Cash Deposit or Letter of Credit, unless Tenant re-commences business operations in all or part of the Premises. The preceding sentence shall not apply to the cash deposit or letter of credit security of any subtenant or assignee of the Lease.

6.  Abatement and Resumption of Basic Annual Rent and Operating Expense Payments . After the Cash Deposit and Letter of Credit are fully exhausted, Tenant’s obligation to pay Basic Annual Rent or Additional Rent (exc


 
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