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SEVENTH LEASE AMENDMENT TO LEASE AGREEMENT THIS SEVENTH LEASE AMENDMENT TO LEASE AGREEMENT

Lease Agreement

SEVENTH LEASE AMENDMENT TO LEASE AGREEMENT THIS SEVENTH LEASE AMENDMENT TO LEASE AGREEMENT | Document Parties: PHARMACEUTICAL PRODUCT DEVELOPMENT INC | Duke Realty Corporation | DUKE REALTY LIMITED PARTNERSHIP | Indiana Limited Partnership | PPD DEVELOPMENT LP | PPD Development, Inc | PPD GP, LLC | Weeks Realty, LP You are currently viewing:
This Lease Agreement involves

PHARMACEUTICAL PRODUCT DEVELOPMENT INC | Duke Realty Corporation | DUKE REALTY LIMITED PARTNERSHIP | Indiana Limited Partnership | PPD DEVELOPMENT LP | PPD Development, Inc | PPD GP, LLC | Weeks Realty, LP

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Title: SEVENTH LEASE AMENDMENT TO LEASE AGREEMENT THIS SEVENTH LEASE AMENDMENT TO LEASE AGREEMENT
Governing Law: North Carolina     Date: 2/26/2008
Industry: Biotechnology and Drugs     Sector: Healthcare

SEVENTH LEASE AMENDMENT TO LEASE AGREEMENT THIS SEVENTH LEASE AMENDMENT TO LEASE AGREEMENT, Parties: pharmaceutical product development inc , duke realty corporation , duke realty limited partnership , indiana limited partnership , ppd development lp , ppd development  inc , ppd gp  llc , weeks realty  lp
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Exhibit 10.251

SEVENTH LEASE AMENDMENT TO LEASE AGREEMENT

THIS SEVENTH LEASE AMENDMENT TO LEASE AGREEMENT (hereinafter referred to as the “Seventh Amendment”) is made as of the 6th day of February 2006, by and between DUKE REALTY LIMITED PARTNERSHIP, an Indiana limited partnership doing business in North Carolina as Duke Realty of Indiana Limited Partnership, successor by merger to Weeks Realty, L.P. (hereinafter referred to as Landlord”) and PPD DEVELOPMENT LP, a Texas limited partnership and successor in interest to PPD Development, Inc. (hereinafter referred to as “Tenant”).

WITNESSETH:

WHEREAS, pursuant to a Lease Agreement dated June 26, 1998 by and between Landlord and Tenant, as amended by that certain First Lease Amendment to Lease Agreement dated October 28, 1998, and as amended by that certain Second Amendment to Lease Agreement dated October 1, 2002, and as amended by that certain Third Lease Amendment to Lease Agreement dated September 22, 2003, and as amended by that certain Fourth Lease Amendment to Lease Agreement dated March 31, 2005, and as amended by that certain Fifth Lease Amendment to Lease Agreement dated July 7, 2005, and as further amended by that certain Sixth Lease Amendment to Lease Agreement dated December 30, 2005 (the Lease Agreement, and all amendments thereto shall be referred to herein collectively as the “Lease”), Landlord leased to Tenant certain premises consisting of approximately 96,145 rentable square feet (the “Premises”) in a building located on certain land (the “Land”) which had been provided the address of 4023 Paramount Parkway, but is now known as 3900 South Paramount Parkway, Morrisville, Wake County, North Carolina 27560, all as more particularly described in the Lease; and

WHEREAS, the parties hereto desire to modify the Lease to reflect a termination option; and

NOW, THEREFORE, for and in consideration of Ten Dollars ($10.00) paid by Landlord and Tenant to one another, and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged by Landlord and Tenant, Landlord and Tenant amend the Agreement as follows:

1. Surrender of a Portion of the Premises. Pursuant to Section 17.03(b) of that certain Office Lease by and between Landlord and Tenant dated December 29, 2005 for the lease of approximately 30,000 rentable square feet of space in a building to be constructed by Landlord at 3800 Paramount Parkway, Morrisville, North Carolina 27560 (the “3800 Lease”), Tenant has the option to surrender one or more of Suites 150, 225 and 250 (each a “Suite”) of the Premises if at anytime prior to the third anniversary of the execution of the 3800 Lease, the rentable square footage of the premises under the 3800 Lease is increased to 60,000 rentable square feet pursuant to the terms of Section 17.03(b) of the 3800 Lease. (Tenant acknowledging, however, that while Tenant shall have the right to surrender less than all three of said Suites, Tenant shall not have the right to surrender only a portion of a Suite). In order to exercise said surrender right, Tenant shall notify Landlord of such exercise within ten (10) days following Tenant’s execution and delivery of an amendment to the 3800 Lease evidencing the expansion of the premises under the 3800 Lease, and together with such notice Tenant shall deliver to Landlord an amount equal to all accrued and unpaid interest together with the unamortized portion of any tenant improvement allowance attributable to such Suite(s) that are being surrendered under the Lease. In the event Tenant exercises this surrender right, Landlord and Tenant shall enter into an amendment to the Lease whereby with respect to such Suite(s) under the Lease. Landlord and Tenant shall be released and discharged from their respective obligations under the Lease with respect to such Suite(s), and neither party shall have any further liability under the Lease with respect to such Suite(s), excluding, however, the obligations of Tenant attributable to any period of the Lease on or prior to the Surrender Date (including without limitation the payment of Minimum Annual Rent and the Annual Rental Adjustment) and any obligations of Tenant under the Lease which survive termination thereof. The effective date of the surrender of such Suite(s) (the “Surrender Date”) shall be the commencement date of the lease of such expansion space under the 3800 Lease.

2. Severability. In the event any term, covena


 
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