SECOND AMENDMENT TO LEASE AGREEMENT

Exhibit 10.1

SECOND AMENDMENT TO LEASE AGREEMENT
BETWEEN JOSEPH V. FISHER, LLC (“LESSOR”) AND AMICAS, INC. f/k/a
VITALWORKS, INC. f/k/a INFOCURE CORPORATION (“LESSEE”)

     THIS SECOND AMENDMENT TO LEASE AGREEMENT (“Second Amendment”), dated this 27 ^th day of February , 2009, by and among JOSEPH V. FISHER, LLC, a Florida Limited Liability Corporation, manager of the Premises by assignment from the Owners, Joseph V. Fisher and Laverne B. Fisher, jointly and severally (such owners and managers are hereinafter collectively referred to as the “Lessor” and AMICAS, Inc., f/k/a Vital Works Inc., f/k/a InfoCure Corporation, a Delaware corporation, (the “Lessee”) (collectively the “Parties”).

WITNESSETH:

     WHEREAS, the parties entered into a Lease Agreement dated March 13, 2001 (the “Lease”); which Lease was amended by Addendum to Lease Agreement dated March 5, 2008 (“First Amendment”) for the premises