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L E A S E

Lease Agreement

L E A S E | Document Parties: CYTRX CORP | Newgate Properties, LLC | RXI Pharmaceutical Corporation You are currently viewing:
This Lease Agreement involves

CYTRX CORP | Newgate Properties, LLC | RXI Pharmaceutical Corporation

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Title: L E A S E
Governing Law: Massachusetts     Date: 11/14/2007
Industry: Biotechnology and Drugs     Law Firm: Ropes Gray,Fletcher, Tilton & Whipple, P.C.     Sector: Healthcare

L E A S E, Parties: cytrx corp , newgate properties  llc , rxi pharmaceutical corporation
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Exhibit 10.2
L E A S E
     THIS LEASE is dated as of September 25, 2007, 2007 between the Landlord and the Tenant named below, and is of space in the Building described below.
ARTICLE 1
BASIC DATA; DEFINITIONS
      1.1 Basic Data . Each reference in this Lease to any of the following terms shall be construed to incorporate the data for that term set forth in this Section:
      Landlord : Newgate Properties, LLC
      Landlord’s Address : 100 Institute Road, Worcester, MA 01609
      Tenant : RXI Pharmaceuticals Corporation
      Tenant’s Address : One Innovation Drive, Worcester, MA
      Property : 60-68 Prescott Street, One Gateway Place, Worcester, MA
      Building : The building commonly known and numbered as 60 Prescott Street, Worcester, MA.
      Premises : The portion of the first floor of the Building consisting of approximately 2,882 usable square feet of office space and a portion of the third floor consisting of approximately 2,425 usable square feet of laboratory space, all as more particularly shown on Exhibit A attached hereto. The specific area of the Premises shall be determined by the registered architect for the Landlord in accordance with the methodology set forth in Exhibit A-1 .
      Basic Rent : The Basic Rent for the Premises is as follows:
         
RENTAL PERIOD   MONTHLY BASIC RENT
Rent Commencement Date to July 31, 2009
  $ 15,036.50  
           Security Deposit. Upon the execution of the Lease, the Tenant shall be obligated to pay to the Landlord one month’s rent (the “Security Deposit”) in the manner described at Section 1.1 hereof, which shall be held as security for the Tenant’s performance as herein provided and refunded to the Tenant at the end of the Lease subject to the Tenant’s satisfactory compliance with the conditions hereof. The Landlord shall not be obligated to pay interest on or segregate such amount from other funds of the Landlord.

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      Lease Commencement Date : Upon Substantial Completion of the Landlord’s Improvements described herein by the Landlord and delivery to the Tenant in accordance with the terms of this Lease. The parties shall acknowledge the Lease Commencement Date on the form attached hereto as Exhibit B .
      Rent Commencement Date: Upon the later of: (i) Landlord’s Substantial Completion of the Landlord’s Improvements described herein by the Landlord; or (ii) December 1, 2007.
      Term : One term of approximately twenty (20) months (“ Initial Term ”), commencing on the Lease Commencement Date and expiring on the last day of the calendar month after the expiration of twenty (20) calendar months after the Rent Commencement Date. Notwithstanding anything to the contrary herein, Tenant shall have the options (i) to terminate this Lease effective on any date at least six (6) months after the Term Commencement Date as may be specified by at least ninety (90) days’ notice to Landlord (in which event this Lease shall terminate on such effective date with the same effect as if such effective date were the date originally specified herein for the expiration hereof); and (ii) in the event Tenant has signed a lease of other space in Gateway Park to which Tenant intends to relocate its operations from the Premises, by notice to Landlord, either to extend the Term of this Lease on a month-to-month basis until, or to terminate this Lease early when, such other leased space has been prepared for and Tenant has accomplished such relocation and Tenant’s occupancy.
      Option Space: During the term of this Lease, the Tenant shall have the option to add to the Premises that portion of the Building in Exhibit D marked as “ Option Space ” upon not less than sixty (60) days written notice to the Landlord. It is agreed that the Option Space consists of approximately 1,030 usable square feet of floor area. Upon such exercise, the Option Space shall be deemed to be a part of the Premises and the Basic Rent shall be increased at a rate of usable square footage of the Option Space multiplied by $34.00 per annum. In addition, Tenant shall have full access to Room 3238, the common area immediately across the corridor from the open lab space. Tenant shall not have the right to use the Option Space absent exercise of the option by written notice to the Landlord. In addition, in the event Blue Sky Biotech vacates the office space set forth in blue and marked “Blue Sky” on Exhibit E, Tenant shall have a first right of refusal to occupy such space. It is agreed that the Blue Sky space is approximately 500 usable square feet.
      Initial General Liability Insurance : $1,000,000 per occurrence/$2,000,000 aggregate (combined single limit) for property damage, bodily injury or death.
      Permitted Uses : General office uses and scientific laboratory space for research and development in the life sciences field of study which shall be conducted in compliance with all applicable municipal, state and federal laws, rules and regulations and in all events the Permitted Uses shall be conducted in a manner so as to not be unreasonably disruptive in any manner to any other tenant or occupant in the Building. Tenant will procure and maintain in full force and effect all licenses and permits which may be required for any use made of the Premises.
      1.2 Definitions . In addition to the terms defined throughout this Lease, when used in Lease, the capitalized terms set forth below shall bear the meanings set forth below.

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      Business Day : All days except Saturdays, Sundays, local, state and federal holidays.
      Force Majeure : Collectively and individually, strikes or other labor trouble, fire or other casualty, acts of God, governmental preemption of priorities or other controls in connection with a national or other public emergency or shortages of fuel, supplies or labor resulting therefrom, or any other cause, whether similar or dissimilar, beyond the reasonable control of the party required to perform an obligation.
      Substantial Completion : Shall mean that the Landlord’s Improvements have been completed in accordance with Exhibit A and the plans and specifications approved by Tenant so that either a temporary or a permanent certificate of occupancy has been issued by the City of Worcester, subject to minor items of repair, correction, adjustment or completion set forth in a so-called “punch list” signed by Landlord and Tenant, the incompletion of which do not and the subsequent completion of which will not, adversely affect or interfere with Tenant’s use of the Premises or the completion of Tenant’s Work. Landlord will complete the punch list items within thirty (30) days after the Lease Commencement Date. In the event the punch list items are not complete within thirty (30) days after the Lease Commencement Date, Tenant shall have the right to withhold thirty percent of the Monthly Basic Rent until such punch list items are completed.
      1.3 Enumeration of Exhibits . The following Exhibits are a part of this Lease, are incorporated herein by reference attached hereto, and are to be treated as a part of this Lease for all purposes. Undertakings contained in such Exhibits are agreements on the part of Landlord and Tenant, as the case may be, to perform the obligations stated therein.
     Exhibit A   —     Plan of the Premises and Landlord Improvements
     Exhibit A-1   —     Measurement Methodology
     Exhibit B   —     Lease Commencement Date Acknowledgment
     Exhibit C   —     WPI Equipment and Vivarium Space Subject to Tenant Use
     Exhibit D   —     Option Space
     Exhibit E   —     First Floor Option Office Space
 
ARTICLE 2
PREMISES AND APPURTENANT RIGHTS
      2.1 Lease of Premises . Landlord hereby leases and demises to Tenant and Tenant hereby leases from Landlord the Premises for the Term and upon the terms and conditions hereinafter set forth.
      2.2 Appurtenant Rights and Reservations .
          (a) Tenant shall have, as appurtenant to the Premises, the non-exclusive right to use, and permit its invitees, employees and authorized subtenants to use in common with Landlord and others, public or common walkways necessary for access to the Building and the Premises and the access roads, driveways, loading areas, pedestrian sidewalks, landscaped areas,

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bathrooms and other areas or facilities, if any, which are located in or on the Property (the “Common Facilities”) ; but such rights shall always be subject to reasonable rules and regulations from time to time established by Landlord pursuant to Section 14.5 (the “ Rules and Regulations ”) and to the right of Landlord to designate and change from time to time areas and facilities so to be used, provided, however, that any newly designated or changed Common Facilities shall be substantially similar to those in existence on the Lease Commencement Date.
          (b) Landlord shall have the right to place in the Premises (but in such manner as to cause no interference with Tenant’s use of the Premises) utility lines, equipment, stacks, pipes, conduits, ducts and the like.
          (c) Tenant shall have the right, as appurtenant to the Premises, the non-exclusive and subordinate right to utilize the kitchen area, conference rooms and auditorium within that portion of the Building leased and occupied by Worcester Polytechnic Institute (“ WPI ”) as may be reasonably required by Tenant and in all events subject to the scheduling requirements of WPI.
          (d) In conjunction with the Lease, Tenant shall be provided the opportunity to utilize certain pieces of equipment and space owned by WPI, including but not limited to the Vivarium located within that portion of the Building leased by WPI. A list of such equipment and a plan of such space as are subject to this provision is attached as Exhibit C . Tenant shall be obligated to coordinate the use of the equipment and the Vivarium with WPI and shall pay to WPI a reasonable rate to be agreed to on a per hour or per animal basis for the use of such equipment and the Vivarium.
ARTICLE 3
BASIC RENT AND SECURITY DEPOSIT
      3.1 Payment of Basic Rent .
          (a) Tenant agrees to pay the Basic Rent to Landlord, or as directed by Landlord, commencing on the Rent Commencement Date, without offset, abatement, deduction or demand except as set forth in this Lease. Basic Rent shall be payable in equal monthly installments, in advance, on the first day of each and every calendar month during the Term of this Lease, to Landlord at Landlord’s Address or at such other place as Landlord shall from time to time designate by notice, in lawful money of the United States. In the event that any installment of Basic Rent is not paid within twenty (20) business days of when due, Tenant shall pay, in addition to any charges under the Lease, an administrative fee equal to five (5%) percent of the overdue payment. Landlord and Tenant agree that all amounts due from Tenant under or in respect of this Lease shall be considered as rental reserved under this Lease for all purposes, including without limitation regulations promulgated pursuant to the Bankruptcy Code, and including further without limitation Section 502(b) thereof.
          (b) Basic Rent for any partial month shall be pro-rated on a daily basis, and if the first day on which Tenant must pay Basic Rent shall be other than the first day of a calendar month, the first payment which Tenant shall make to Landlord shall be equal to a proportionate

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part of the monthly installment of Basic Rent for the partial month from the first day on which Tenant must pay Basic Rent to the last day of the month in which such day occurs.
          (c) Basic Rent is full service gross rent and includes all real estate taxes, insurance, utilities, operating expenses and other costs and expenses except as herein expressly provided.
ARTICLE 4
CONDITION OF THE PREMISES
      4.1 Condition of the Premises. Subject to the completion of Landlord’s Improvements by the Landlord, at Landlord’s expense, relative to the office space portion of the Premises and the work described in this Section and (the “ Landlord’s Improvements ”), the Premises are being leased in their “AS IS” condition. The Landlord agrees that at the time of delivery (i) the Premises shall be in conformity with all applicable laws, ordinances, rules and regulations, (ii) the Premises shall be free of latent defects, (iii) the Landlord’s Improvements and the work described in this Section shall be completed in a good and workmanlike manner, using only new materials, (iv) the Landlord, at the Landlord’s expense, shall have obtained all permits required for the completion and occupancy of the Landlord’s Improvements and the work described in this Section, (v) all base building mechanical, electrical, plumbing and other Building systems shall be in good operating condition and repair, and (vi) the Premises shall be free and clear of all tenants and occupants. If the Landlord’s Improvements and the work described in this Section are not substantially completed by December 15, 2007, the Landlord will credit one-half day’s Basic Rent for each day after December 15, and one full day’s Basic Rent for each day after December 31, that the office space is not Substantially Completed, excluding, any delays that are attributable to RXi. If the Landlord’s Improvements and the work described in this Section are not complete by February 1, 2008, then the Tenant may terminate this Lease by delivering written notice to the Landlord, in which case this Lease shall terminate on the date set forth in the notice. There are no Landlord’s Improvements contemplated or anticipated to the laboratory portion of the Premises and any such work shall be conducted by Tenant pursuant to Section 5.2.
ARTICLE 5
USE OF PREMISES
      5.1 Permitted Use .
          (a) Tenant agrees that the Premises shall be used and occupied by Tenant and its authorized subtenants only for Permitted Uses (defined hereinabove) and for no other use without Landlord’s express written consent which consent may be withheld or conditioned in the sole and unfettered discretion of the Landlord. It shall be the Tenant’s responsibility and obligation to obtain and maintain the proper licenses and permits for the Tenant’s business at the Tenant’s expense and the Landlord makes no representation with respect to the availability or

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non-availability of such licenses or permits. Landlord represents and warrants that the Premises may be used for the Permitted Uses under applicable zoning and other land use laws.
          (b) Tenant agrees for itself and its authorized subtenants to conform to the following provisions during the Term of this Lease:
               (i) Tenant will not place on the exterior of the Premises, Property or on any part of the Building, any sign, symbol, advertisement or the like, other than the existing signs located on the Property, without first obtaining Landlord’s consent, which shall not be unreasonably withheld, for interior signs. Landlord agrees to cooperate with Tenant as to sign locations. With regard to the installation of any signs, the Tenant shall comply with all provisions of Section 5.2 herein. The Tenant shall maintain and repair the Tenant’s signs located on the Property as of the date of this Lease and shall bear all costs and expenses associated therewith. Tenant agrees to have a sign installed in the lobby of the Building prior to the Rent Commencement Date and to permit Landlord to advertise the tenancy of the Tenant in the Building in accordance with Section 14.10 (the “ Publicity Restrictions ”):
               (ii) Tenant shall not perform any act or carry on any practice which may injure the Premises, or any other part of the Building and shall operate the Premises in a reputable manner;
               (iii) Tenant shall, in its use of the Premises, comply with the requirements of all applicable governmental laws, rules and regulations, including, without limitation, the Americans With Disabilities Act of 1990 and the regulations of the Massachusetts Architectural Access Board, subject to Tenant’s right to contest the same in good faith and postpone such compliance during the pendency of such contest; provided, that Tenant shall not be responsible for ensuring the Premises complies with such laws when (i) such legal requirements are imposed on a Building-wide basis or would be generally applicable to any office space and do not relate to Tenant’s particular manner of use of the Premises, (ii) a notice of violation or order was issued prior to the date Tenant is given possession of the Premises, or (iii) such legal requirements require investigating, certifying, monitoring, encapsulating, removing or in any way dealing with asbestos or hazardous substances unless such asbestos or hazardous substances were introduced into the Premises by Tenant; and
               (iv) Tenant agrees that the Premises and any other part of the Building will be used and occupied in a careful, reasonably safe and proper manner and that Tenant will not permit waste therein that results from negligence or breach hereof on the part of Tenant, its employees, agents, invitees and others acting on its behalf.
      5.2 Installations and Alterations by Tenant .
          (a) Tenant shall be responsible for any and all alterations, additions and improvements (“ Improvements ”) that are required to complete the Premises such that the Premises can be used for the Tenant’s purposes, with the sole exclusion being the Landlord’s

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Improvements. Prior to any structural Improvements being made, the Tenant shall provide any and all plans and specifications and a list of contractors for the prior consent and approval of the Landlord, which shall not be unreasonably withheld, delayed or conditioned. All work shall be (i) performed in a good and workmanlike manner and in compliance with all applicable laws, ordinances and regulations; (ii) be made at Tenant’s sole cost and expense (excluding the Landlord’s Improvements); (iii) other than Tenant’s Removable Property, become part of the Premises and the property of Landlord; and (iv) be coordinated with any work being performed by Landlord in such a manner as not to damage the Building or interfere with the construction or operation of the Building.
          (b) Tenant shall be responsible for the installation and payment of all phone systems desired by the Tenant at the Premises.
          (c) All articles of personal property and all laboratory hoods and other business and trade fixtures, inventory, machinery and equipment and furniture owned or installed by Tenant solely at its expense in the Premises (“ Tenant’s Removable Property ”) shall remain the property of Tenant and may be removed by Tenant at any time prior to the expiration or earlier termination of the Term, provided that Tenant, at its expense, shall repair any damage to the Building caused by such removal.
          (d) Notice is hereby given that Landlord shall not be liable for any labor or materials furnished or to be furnished to Tenant upon credit, and that no mechanic’s or other lien for any such labor or materials shall attach to or affect the reversion or other estate or interest of Landlord in and to the Premises, the Building or the Property. Tenant agrees that if, any lien is filed against all or any part of the Property for work claimed to have been done for, or materials claimed to have been furnished to, Tenant or its agents, employees or independent contractors, Tenant, at its sole cost and expense, shall cause such lien to be dissolved within ten (10) business days after receipt of notice that such lien has been filed, by the payment thereof or by the filing of a bond sufficient to accomplish the foregoing. If Tenant shall fail to discharge any such lien within ten (10) business days’ notice, Landlord may, at its option, discharge such lien and treat the cost thereof (including reasonable attorneys’ fees incurred in connection therewith) as payable within ten (10) days of demand, it being expressly agreed that such discharge by Landlord shall not be deemed to waive or release the Event of Default in not discharging such lien. Tenant shall indemnify and hold Landlord harmless from and against any and all expenses, liens, claims, liabilities and damages based on or arising, directly or indirectly, by reason of the making of any alterations, additions or improvements by or on behalf of Tenant to the Premises under this Section, which obligation shall survive the expiration or termination of this Lease.
          (e) In the course of any work being performed by Tenant (including, without limitation, the “field installation” of any Tenant’s Removable Property), Tenant agrees to use labor compatible with that being employed by Landlord for work in the Building or on the Property or other buildings owned by Landlord or its affiliates (which term, for purposes hereof, shall include, without limitation, entities which control or are under common control with or are controlled by Landlord or, if Landlord is a partnership or limited liability company, by any partner or member of Landlord and which may include Consigli Construction Co., Inc.) and not to employ or permit the use of any labor or otherwise take any action which might result in a

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labor dispute involving personnel providing services in the Building or on the Property pursuant to arrangements made by Landlord. Tenant intends to use Conlangelo & Son as its contractor and Landlord has no objection to same.
          (f) No Improvements shall be performed in a manner that is unreasonably disruptive to other tenants, or invitees of Landlord in the Building, or to the public in general, or which causes unreasonable noise, vibration, dust or is unreasonably unclean or unsightly. Upon notice from the Landlord, subject to Sections 10.4 and 11.2, the Tenant shall, at its sole cost and expense, repair any damage to the Building or the Property caused by or resulting from any Improvements.
          (g) To the fullest extent permitted by law, Tenant shall indemnify and hold harmless Landlord and its agents and employees from and against all claims, damages, losses and expenses (except if arising in whole or in part from the negligence, willful misconduct or breach hereof on the part of Landlord or its agents, employees or contractors) including, but not limited to, reasonable attorneys’ fees, to the extent arising out of or resulting from any Improvements, provided that such claim, damage, loss or expense is attributable to bodily injury, sickness, disease or death, or to injury to or destruction of tangible property, including loss of use resulting therefrom, but only to the extent caused in whole or in part by negligent acts or willful misconduct of Tenant or its contractors or anyone for whose acts they may be liable. Such obligation shall not be construed to negate, abridge, or reduce other rights or obligations of indemnity elsewhere in this Lease or which would otherwise exist as to a party or person described in this Article.
          (h) Tenant shall ensure that all contractors (which include sub-contractors of any contractor) who will enter the Premises or the Building, and others employed directly or indirectly by them, shall purchase insurance which, at a minimum, shall be consistent with the following:
  (a)   insurance covering workers’ or workmen’s compensation claims.
 
  (b)   commercial general liability insurance covering claims for personal injury and property damage.
 
  (c)   During the period of any construction of the Tenant’s Improvements or alterations pursuant to this Section, contractor’s or builder’s “all risk” insurance covering property damage and loss of use claims.
The insurance required by this Article shall be written for not less than limits specified herein for Tenant’s Insurance. Coverages, whether written on an occurrence or claims-made basis, shall be maintained without interruption from date of commencement of the Work until date of final payment and termination of any coverage required to be maintained after final payment.
Original certificates of insurance evidencing full compliance with this Article shall be delivered to Landlord prior to commencement of the Improvements. These certificates and the insurance

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policies required by this Article shall expressly name Landlord and Landlord’s mortgagee as additionally insured, and shall contain a provision that coverages afforded under the policies will not be canceled or allowed to expire until at least thirty (30) days’ prior written notice has been given to Landlord.
      5.3 Cleanliness, Maintenance of Certain Equipment, Trash
     The Landlord shall be responsible for storage and disposing of any non-hazardous trash and waste. Tenant shall be responsible for placing all such trash in the appropriate receptacles provided by the Landlord. With regard to any hazardous or infectious materials defined in any federal or state laws, rules or regulations, used in the Premises by Tenant or any of Tenant’s officers, employees, contractors or agents, the Tenant shall be responsible for disposing such materials within or from the Premises at its sole cost and expense and in accordance with all applicable law, rule or regulation. The Tenant shall be required to comply with any and all municipal, state or federal regulations or laws with regard to the storage, handling and disposal of hazardous material and with any reasonable guidelines as developed for the Property by the Landlord.
ARTICLE 6
ASSIGNMENT AND SUBLETTING
      6.1 Terms and Conditions .
          (a) Tenant and Landlord covenant and agree that, except in the case of a sublease or assignment in connection with a merger, consolidation or sale of substantially all of its assets by the Tenant, the Tenant may not sublet or assign all or a portion of the Premises wit

 
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