FIRST AMENDMENT TO LEASE

Exhibit 10.35

FIRST AMENDMENT TO LEASE

        THIS FIRST AMENDMENT TO LEASE (this "Amendment") is executed as of August 17, 2006, by and between ECI SHERMAN PLAZA LLC, a Delaware limited liability company ("Landlord"), and HEMACARE CORPORATION., a California corporation ("Tenant").

Recitals

        A.    Landlord and Tenant entered into a Lease Agreement dated February 10, 2006 (the "Lease"). Under the terms of the Lease Tenant leases from Landlord the following three (3) spaces in the building located at 15400 Sherman Way, Van Nuys, California (the "Building"):

•           (i)  the Initial Ground Floor Premises containing 7,178 rentable square feet on the first (1 ^st ) floor of the Building, and the Initial Third Floor Premises containing 4,455 rentable square feet on the third (3 ^rd ) floor of the Building (together, the "Initial Premises"), and

           (ii)  the "Additional Premises" containing 8,011 rentable square feet third (3 ^rd ) floor of the Building.

        B.    The anticipated delivery date of the Initial Premises to Tenant was May 1, 2006.

        C.    Landlord and Tenant desire to stipulate that Landlord delivered the Initial Premises to Tenant on August 14, 2006.

        D.    Landlord and Tenant desire to change the Delivery Deadline for the Additional Premises from August 1, 2006 to September 1, 2006 (the "Revised Delivery Deadline").

        E.    By letter dated May 5, 2006 Landlord relocated (i) the Initial Third Floor Premises from Suite 320 to Suite 330, and (ii) the Additional Premises from Suite 360 to Suite 350. The approximate configuration and location of Suites 330 and 350 are shown on Exhibit A attached hereto. Suites 330 and 350 are together herein called the "Relocation Space".

        NOW, THEREFORE, in consideration of the foregoing recitals and the mutual covenants contained herein, and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto agree as that the Lease is amended as follows:

        1.     Definitions.     Except as otherwise expressly provided herein to the contrary, all