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EX-10.21 MASTER LEASE AGREEMENT

Lease Agreement

EX-10.21 MASTER LEASE AGREEMENT | Document Parties: PREDIX PHARMACEUTICALS, INC You are currently viewing:
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PREDIX PHARMACEUTICALS, INC

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Title: EX-10.21 MASTER LEASE AGREEMENT
Governing Law: Connecticut     Date: 8/3/2005

EX-10.21 MASTER LEASE AGREEMENT, Parties: predix pharmaceuticals  inc
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EXHIBIT 10.21

*LEAS1998*

MASTER LEASE AGREEMENT

DATED AS OF DECEMBER 3, 2002 ("AGREEMENT")

THIS AGREEMENT is between GENERAL ELECTRIC CAPITAL CORPORATION (together

with its successors and assigns, if any, "LESSOR") and PREDIX PHARMACEUTICALS,

INC. ("LESSEE"). Lessor has an office at 401 Merritt 7 Suite 23, Norwalk, CT

06851-1177. Lessee is a corporation organized and existing under the laws of the

state of Delaware. Lessee's mailing address and chief place of business is 10 K

Gill Street, Woburn, MA 01801. This Agreement contains the general terms that

apply to the leasing of Equipment from Lessor to Lessee. Additional terms that

apply to the Equipment (term, rent, options, etc.) shall be contained on a

schedule ("SCHEDULE").

1. LEASING:

(a) Lessor agrees to lease to Lessee, and Lessee agrees to lease from

Lessor, the equipment and the property ("EQUIPMENT") described in any Schedule

signed by both parties.

(b) Lessor shall purchase Equipment from the manufacturer or supplier

("SUPPLIER") and lease it to Lessee if on or before the Last Delivery Date

Lessor receives (i) a Schedule for the Equipment, (ii) evidence of insurance

which complies with the requirements of Section 9, and (iii) such other

documents as Lessor may reasonably request. Each of the documents required above

must be in form and substance satisfactory to Lessor. Lessor hereby appoints

Lessee its agent for inspection and acceptance of the Equipment from the

Supplier. Once the Schedule is signed, the Lessee may not cancel the Schedule.

2. TERM, RENT AND PAYMENT:

(a) The rent payable for the Equipment and Lessees right to use the

Equipment shall begin on the earlier of (i) the date when the Lessee signs the

Schedule and accepts the Equipment or (ii) when Lessee has accepted the

Equipment tinder a Certificate of Acceptance ("LEASE COMMENCEMENT DATE"). The

term of this Agreement shall be the period specified in the applicable Schedule.

The word "term" shall include all basic and any renewal terms.

(b) Lessee shall pay rent to Lessor at its address stated above, except as

otherwise directed by Lessor. Rent payments shall be in the amount set forth in,

and due as stated in the applicable Schedule. If any Advance Rent (as stated in

the Schedule) is payable, it shall be due when the Lessee signs the Schedule.

Advance Rent shall be applied to the first rent payment and the balance, if any,

to the final rent payment(s) under such Schedule. In no event shall any Advance

Rent or any other rent payments be refunded to Lessee. If rent is not paid

within ten (10) days of its due date, Lessee agrees to pay a late charge of five

cents ($.05) per dollar on, and in addition to, the amount of such rent but not

exceeding the lawful maximum, if any.

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3. RENT ADJUSTMENT:

(a) If, solely as a result of Congressional enactment of any law

(including, without limitation, any modification of, or amendment or addition

to, the Internal Revenue Code of 1986, as amended, ("CODE")), the maximum

effective corporate income tax rate (exclusive of any minimum tax rate) for

calendar-year taxpayers ("EFFECTIVE RATE") is higher than thirty-five percent

(35%) for any year during the lease term, then Lessor shall have the right to

increase such rent payments by requiring payment of a single additional sum. The

additional sum shall be equal to the product of (i) the Effective Rate

(expressed as a decimal) for such year less .35 (or, in the event that any

adjustment has been made hereunder for any previous year, the Effective Rate

(expressed as a decimal) used in calculating the next previous adjustment) times

(ii) the adjusted Termination Value (defined below), divided by (iii) the

difference between the new Effective Rate (expressed as a decimal) and one (1).

The adjusted Termination Value shall be the Termination Value (calculated as of

the first rent due in the year for which the adjustment is being made) minus the

Tax Benefits that would be allowable under Section 168 of the Code (as of the

first day of the year for which such adjustment is being made and all future

years of the lease term). The Termination Values and Tax Benefits are defined on

the Schedule. Lessee shall pay to Lessor the Rill amount of the additional rent

payment on the later of (i) receipt of notice or (ii) the first day of the year

for which such adjustment is being made.

(b) Lessee's obligations under this Section 3 shall survive any expiration

or termination of this Agreement.

4. TAXES:

(a) If permitted by law, Lessee shall report and pay promptly all taxes,

fees and assessments due, imposed, assessed or levied against any Equipment (or

purchase, ownership, delivery, leasing, possession, use or operation thereof),

this Agreement (or any rents or receipts hereunder), any Schedule, Lessor or

Lessee by any governmental entity or taxing authority during or related to the

term of this Agreement, including, without limitation, all license and

registration fees, and all sales, use, personal property, excise, gross

receipts, franchise, stamp or other taxes, imposts, duties and charges, together

with any penalties, fines or interest thereon (collectively "TAXES"). Lessee

shall have no liability for Taxes imposed by the United States of America or any

state or political subdivision thereof which are on or measured by the net

income of Lessor except as provided in Sections 3 and 14(c). Lessee shall

promptly reimburse Lessor (on an after tax basis) for any Taxes charged to of

assessed against Lessor. Lessee shall show Lessor as the owner of the Equipment

on all tax reports or returns, and send Lessor a copy of each report or return

and evidence of Lessee's payment of Taxes upon request.

(b) Lessee's obligations, and Lessor's rights and privileges, contained in

this Section 4 shall survive the expiration or other termination of this

Agreement.

5. REPORTS:

(a) If any tax or other lien shall attach to any Equipment, Lessee will

notify Lessor in writing, within ten (10) days after Lessee becomes aware of the

tax or lien. The notice shall

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include the full particulars of the tax or lien and the location of such

Equipment on the date of the notice.

(b) Lessee will deliver to Lessor, Lessee's complete financial statements,

certified by a recognized firm of certified public accountants within ninety

(90) days of the close of each fiscal year of Lessee. Lessee will deliver to

Lessor copies of Lessee's quarterly financial report certified by the chief

financial officer of Lessee, within ninety (90) days of the close of each fiscal

quarter of Lessee. Lessee will deliver to Lessor all Forms 10-K and 10-Q, if

any, filed with the Securities and Exchange Commission within thirty (30) days

after the date on which they are filed.

(c) Lessor may inspect any Equipment during normal business hours after

giving Lessee reasonable prior notice.

(d) Lessee will keep the Equipment at the Equipment Location (specified in

the applicable Schedule) and will give Lessor prior written notice of any

relocation of Equipment. If Lessor asks, Lessee will promptly notify Lessor in

writing of the location of any Equipment.

(e) If any Equipment is lost or damaged (where the estimated repair costs

would exceed the greater of ten percent (10%) of the original Equipment cost or

ten thousand and 00/100 dollars ($10,000)), or is otherwise involved in an

accident causing personal injury or property damage, Lessee will promptly and

fully report the event to Lessor in writing.

(f) Lessee will furnish a certificate of an authorized officer of Lessee

stating that he has reviewed the activities of Lessee and that, to the best of

his knowledge, there exists no default or event which with notice or lapse of

time (or both) would become such a default within thirty (30) days after any

request by Lessor.

(g) Lessee will promptly notify Lessor of any change in Lessee's state of

incorporation or organization.

6. DELIVERY, USE AND OPERATION:

(a) All Equipment shall be shipped directly from the Supplier to Lessee.

(b) Lessee agrees that the Equipment will be used by Lessee solely in the

conduct of its business and in a manner complying with all applicable laws,

regulations and insurance policies and Lessee shall not discontinue use of the

Equipment.

(c) Lessee will not move any equipment from the location specified on the

Schedule, without the prior written consent of Lessor.

(d) Lessee will keep the Equipment free and clear of all liens and

encumbrances other than those which result from acts of Lessor.

(e) Lessor shall not disturb Lessee's quiet enjoyment of the Equipment

during the term of the Agreement unless a default has occurred and is continuing

under this Agreement.

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7. MAINTENANCE:

(a) Lessee will, at its sole expense, maintain each unit of Equipment in

good operating order and repair, normal wear and tear excepted. The Lessee shall

also maintain the Equipment in accordance with manufacturer's recommendations.

Lessee shall make all alterations or modifications required to comply with any

applicable law, rule or regulation during the term of this Agreement. If Lessor

requests, Lessee shall affix plates, tags or other identifying labels showing

ownership thereof by Lessor. The tags or labels shall be placed in a prominent

position on each unit of Equipment.

(b) Lessee will not attach or install anything on any Equipment that will

impair the originally intended function or use of such Equipment without the

prior written consent of Lessor. All additions, parts, supplies, accessories,

and equipment ("ADDITIONS") furnished or attached to any Equipment that are not

readily removable shall become the property of Lessor. All Additions shall be

made only in compliance with applicable law. Lessee will not attach or install

any Equipment to or in any other personal or real property without the prior

written consent of Lessor.

8. STIPULATED LOSS VALUE: If for any reason any unit of Equipment becomes

worn out, lost, stolen, destroyed, irreparably damaged or unusable ("CASUALTY

OCCURRENCES") Lessee shall promptly and fully notify Lessor in writing. Lessee

shall pay Lessor the sum of (i) the Stipulated Loss Value (see Schedule) of the

affected unit determined as of the rent payment date prior to the Casualty

Occurrence; and (ii) all rent and other amounts which are then due under this

Agreement on the Payment Date (defined below) for the affected unit. The Payment

Date shall be the next rent payment date after the Casualty Occurrence. Upon

Payment of all sums due hereunder, the term of this lease as to such unit shall

terminate.

9. INSURANCE:

(a) Lessee shall bear the entire risk of any loss, theft, damage to, or

destruction of, any unit of Equipment from any cause whatsoever from the time

the Equipment is shipped to Lessee.

(b) Lessee agrees, at its own expense, to keep all Equipment insured for

such amounts and against such hazards as Lessor may reasonably require. All such

policies shall be with companies, and on terms, reasonably satisfactory to

Lessor. The insurance shall include coverage for damage to or loss of the

Equipment, liability for personal injuries, death or property damage. Lessor

shall be named as additional insured with a loss payable clause in favor of

Lessor, as its interest may appear, irrespective of any breach of warranty or

other act or omission of Lessee. The insurance shall provide for liability

coverage in an amount equal to at least ONE MILLION U.S. DOLLARS ($1,000,000.00)

total liability per occurrence, unless otherwise stated in any Schedule. The

casualty/property damage coverage shall be in an amount equal to the higher of

the Stipulated Loss Value or the full replacement cost of the Equipment. No

insurance shall be subject to any co-insurance clause. The insurance policies

shall provide that the insurance may not be altered or canceled by the insurer

until after thirty (30) days written notice to Lessor. Lessee agrees to deliver

to Lessor evidence of insurance reasonably satisfactory to Lessor.

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(c) Lessee hereby appoints Lessor as Lessee's attorney-in-fact to make

proof of loss and claim for insurance, and to make adjustments with insurers and

to receive payment of and execute or endorse all documents, checks or drafts in

connection with insurance payments. Lessor shall not act as Lessee's

attorney-in-fact unless Lessee is in default. Lessee shall pay any reasonable

expenses of Lessor in adjusting or collecting insurance. Lessee will not make

adjustments with insurers except with respect to claims for damage to any unit

of Equipment where the repair costs are less than the lesser of ten percent

(10%) of the original Equipment cost or ten thousand and 00/100 dollars

($10,000). Lessor may, at its option, apply proceeds of insurance, in whole or

in part, to (i) repair or replace Equipment or any portion thereof, or (ii)

satisfy any obligation of Lessee to Lessor under this Agreement.

10. RETURN OF EQUIPMENT:

(a) At the expiration or termination of this Agreement or any Schedule,

Lessee shall perform any testing and repairs required to place the units of

Equipment in the same condition and appearance as when received by Lessee

(reasonable wear and tear excepted) and in good working order for the original

intended purpose of the Equipment. If required the units of Equipment shall be

deinstalled, disassembled and crated by an authorized manufacturer's

representative or such other service person as is reasonably satisfactory to

Lessor. Lessee shall remove installed markings that are not necessary for the

operation, maintenance or repair of the Equipment. All Equipment will be

cleaned, cosmetically acceptable, and in such condition as to be immediately

installed into use in a similar environment for which the Equipment was

originally intended to be used. All waste material and fluid must be removed

from the Equipment and disposed of in accordance with then current waste

disposal laws. Lessee shall return the units of Equipment to a location within

the continental United States as Lessor shall direct. Lessee shall obtain and

pay for a policy of transit insurance for the redelivery period in an amount

equal to the replacement value of the Equipment. The transit insurance must name

Lessor as the loss payee. The Lessee shall pay for all costs to comply with this

section (a).

(b) Until Lessee has fully complied with the requirements of Section 10(a)

above, Lessee's rent payment obligation and all other obligations under this

Agreement shall continue from month to month notwithstanding any expiration or

termination of the lease term. Lessor may terminate the Lessee's right to use

the Equipment upon ten (10) days notice to Lessee.

(c) Lessee shall provide to Lessor a detailed inventory of all components

of the Equipment including model and serial numbers. Lessee shall also provide

an up-to-date copy of all other documentation pertaining to the Equipment. All

service manuals, blue prints, process flow diagrams, operating manuals,

inventory and maintenance records shall be given to Lessor at least ninety (90)

days and not more than one hundred twenty (120) days prior to lease termination.

(d) Lessee shall make the Equipment available for on-site operational

inspections by potential purchasers at least one hundred twenty (120) days prior

to and continuing up to lease termination. Lessor shall provide Lessee with

reasonable notice prior to any inspection. Lessee shall provide personnel, power

and other requirements necessary to demonstrate electrical, hydraulic and

mechanical systems for each item of Equipment.

<PAGE>

11. DEFAULT AND REMEDIES:

(a) Lessor may in writing declare this Agreement in default if: (i) Lessee

breaches its obligation to pay rent or any other sum when due and fails to cure

the breach within ten (10) days; (ii) Lessee breaches any of its insurance

obligations under Section 9; (iii) Lessee breaches any of its other obligations

and fails to cure that breach within thirty (30) days after written notice from

Lessor; (iv) any representation or warranty made by Lessee in connection with

this Agreement shall be false or misleading in any material respect; (v) Lessee

or any guarantor or other obligor for the Lessee's obligations hereunder

("GUARANTOR") becomes insolvent or ceases to do business as a going concern;

(vi) any Equipment is illegally used; (vii) if Lessee or any Guarantor is a

natural person, any death or incompetency of Lessee or such Guarantor; (viii) a

petition is filed by or against Lessee or any Guarantor under any bankruptcy or

insolvency laws and in the event of an involuntary petition, the petition is not

dismissed within forty-five (45) days of the filing date; (ix) Lessee defaults

under any other material obligation for (A) borrowed money, (B) the deferred

purchase price of property, or (C) payments due under lease agreements; or (x)

there is any dissolution, termination of existence, merger, consolidation or

change in controlling ownership of Lessee or any Guarantor. The default

declaration shall apply to all Schedules unless specifically excepted by Lessor.

(b) After a default, at the request of Lessor, Lessee shall comply with

the provisions of Section 10(a). Lessee hereby authorizes Lessor to peacefully

enter any premises where any Equipment may be and take possession of the

Equipment. Lessee shall immediately pay to Lessor without further demand as

liquidated damages for loss of a bargain and not as a penalty, the Stipulated

Loss Value of the Equipment (calculated as of the rent payment date prior to the

declaration of default), and all rents and other sums then due under this

Agreement and all Schedules. Lessor may terminate this Agreement as to any or

all of the Equipment. A termination shall occur only upon written notice by

Lessor to Lessee and only as to the units of Equipment specified in any such

notice. Lessor may, but shall not be required to, sell Equipment at private or

public sale, in bulk or in parcels, with or without notice, and without having

the Equipment present at the place of sale. Lessor may also, but shall not be

required to, lease, otherwise dispose of or keep idle all or part of the

Equipment. Lessor may use Lessee's premises for a reasonable period of time for

any or all of the purposes stated above without liability for rent, costs,

damages or otherwise. The proceeds of sale, lease or other disposition, if any,

shall be applied in the following order of priorities: (i) to pay all of

Lessor's costs, charges and expenses incurred in taking, removing, holding,

repairing and selling, leasing or otherwise disposing of Equipment; then, (ii)

to the extent not previously paid by Lessee, to pay Lessor all sums due from

Lessee under this Agreement; then (iii) to reimburse to Lessee any sums

previously paid by Lessee as liquidated damages; and (iv) any surplus shall be

retained by Lessor. Lessee shall immediately pay any deficiency in (i) and (ii)

above.

(c) The foregoing remedies are cumulative, and any or all thereof may be

exercised instead of or in addition to each other or any remedies at law, in

equity, or under statute. Lessee waives notice of sale or other disposition (and

the time and place thereof), and the manner and place of any advertising. Lessee

shall pay Lessor's actual attorney's fees incured in connection with the

enforcement, assertion, defense or preservation of Lessor's rights and remedies

under this Agreement, or if prohibited by law, such lesser sum as may be

permitted. Waiver of any default shall not be a waiver of any other or

subsequent default.

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(d) Any default under the terms of this or any other agreement between

Lessor and Lessee may be declared by Lessor a default under this and any such

other agreement.

12. ASSIGNMENT: LESSEE SHALL NOT SELL, TRANSFER, ASSIGN, ENCUMBER OR SUBLET

ANY EQUIPMENT OR THE INTEREST OF LESSEE IN THE EQUIPMENT WITHOUT THE PRIOR

WRITTEN CONSENT OF LESSOR. Lessor may, without the consent of Lessee, assign

this Agreement, any Schedule or the right to eater into a Schedule. Lessee

agrees that if Lessee receives written notice of an assignment from Lessor,

Lessee will pay all rent and all other amounts payable under any assigned

Schedule to such assignee or as instructed by Lessor. Lessee also agrees to

confirm in writing receipt of the notice of assignment as may be reasonably

requested by assignee. Lessee hereby waives and agrees not to assert against any

such assignee any defense, set-off, recoupment claim or counterclaim which

Lessee has or may at any time have against Lessor for any reason whatsoever.

13. NET LEASE: Lessee is unconditionally obligated to pay all rent and other

amounts due for the entice lease term no matter what happens, even if the

Equipment is damaged or destroyed, if it is defective or if Lessee no longer can

use it. Lessee is not entitled to reduce or set-off against rent or other

amounts due to Lessor or to anyone to whom Lessor assigns this Agreement or any

Schedule whether Lessee's claim arises out of this Agreement, any Schedule, any

statement by Lessor, Lessor's liability or any manufacturer's liability, strict

liability, negligence or otherwise.

14. INDEMNIFICATION:

(a) Lessee hereby agrees to indemnify Lessor, its agents, employees,

successors and assigns (on an after tax basis) from and against any and all

losses, damages, penalties, injuries, claims, actions and suits, including legal

expenses, of whatsoever kind and nature arising out of or relating to the

Equipment or this Agreement, except to the extent the losses, damages,

penalties, injuries, claims, actions, suits or expenses result from Lessor's

gross negligence or willful misconduct ("CLAIMS"). This indemnity shall include,

but is not limited to, Lessor's strict liability in tort and Claims, arising out

of (i) the selection, manufacture, purchase, acceptance or rejection of

Equipment, the ownership of Equipment during the term of this Agreement, and the

delivery, lease, possession, maintenance, uses, condition, return or operation

of Equipment (including, without limitation, latent and other defects, whether

or not discoverable by Lessor or Lessee and any claim for patent, trademark or

copyright infringement or environmental damage) or (ii) the condition of

Equipment sold or disposed of after use by Lessee, any sublessee or employees of

Lessee. Lessee shall, upon request, defend any actions based on, or arising out

of, any of the foregoing.

(b) Lessee hereby represents, warrants and covenants that (i) on the Lease

Commencement Date for any unit of Equipment, such unit will qualify for all of

the items of deduction and credit specified in Section C of the applicable

Schedule ("TAX BENEFITS") in the hands of Lessor, and (ii) at no time during the

term of this Agreement will Lessee take or omit to take, nor will it permit any

sublessee or assignee to take or omit to take, any action (whether or not such

act or omission is otherwise permitted by Lessor or by this Agreement), which

will result in the disqualification of any Equipment for, or recapture of, all

or any portion of such Tax Benefits.

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(c) If as a result of a breach of any representation, warranty or covenant

of the Lessee contained in this Agreement or any Schedule (i) tax counsel of

Lessor shall determine that Lessor is not entitled to claim on its Federal

income tax return all or any portion of the Tax Benefits with respect to any

Equipment, or (ii) any Tax Benefit claimed on the Federal income tax return of

Lessor is disallowed or adjusted by the Internal Revenue Service, or (iii) any

Tax Benefit is recalculated or recaptured (any determination, disallowance,

adjustment, recalculation or recapture being a "LOSS"), then Lessee shall pay to

Lessor, as an indemnity and as additional rent, an amount that shall, in the

reasonable opinion of Lessor, cause Lessor's after-tax economic yields and cash

flows to equal the Net Economic Return that would have been realized by Lessor

if such Loss had not occurred. Such amount shall be payable upon demand

accompanied by a statement describing in reasonable detail such Loss and the

computation of such amount. The economic yields and cash flows shall be computed

on the same assumptions, including tax rates as were used by Lessor in

originally evaluating the transaction ("NET ECONOMIC RETURN"). If an adjustment

has been made under Section 3 then the Effective Rate used in the next preceding

adjustment shall be substituted.

(d) All references to Lessor in this Section 14 include Lessor and the

consolidated taxpayer group of which Lessor is a member. All of Lessor's rights,

privileges and indemnities contained in this Section 14 shall survive the

expiration or other termination of this Agreement. The rights, privileges and

indemnities contained herein are expressly made for the benefit of, and shall be

enforceable by Lessor, its successors and assigns.

15. DISCLAIMER: LESSEE ACKNOWLEDGES THAT IT HAS SELECTED THE EQUIPMENT WITHOUT

ANY ASSISTANCE FROM LESSOR, ITS AGENTS OR EMPLOYEES. LESSOR DOES NOT MAKE, HAS

NOT MADE, NOR SHALL BE DEEMED TO MAKE OR HAVE MADE, ANY WARRANTY OR

REPRESENTATION, EITHER EXPRESS OR IMPLIED, WRITTEN OR ORAL, WITH RESPECT TO THE

EQUIPMENT LEASED UNDER THIS AGREEMENT OR ANY COMPONENT THEREOF, INCLUDING,

WITHOUT LIMITATION, ANY WARRANTY AS TO DESIGN, COMPLIANCE WITH SPECIFICATIONS,

QUALITY OF MATERIALS OR WORKMANSHIP, MERCHANTABILITY, FITNESS FOR ANY PURPOSE,

USE OR OPERATION, SAFETY, PATENT, TRADEMARK OR COPYRIGHT INFRINGEMENT, OR TITLE.

All such risks, as between Lessor and Lessee, are to be borne by Lessee. Without

limiting the foregoing, Lessor shall have no responsibility or liability to

Lessee or any other person with respect to any of the following; (i) any

liability, loss or damage caused or alleged to be caused directly or indirectly

by any Equipment, any inadequacy thereof, any deficiency or defect (latent or

otherwise) of the Equipment, or any other circumstance in connection with the

Equipment; (ii) the use, operation or performance of any Equipment or any risks

relating to it; (iii) any interruption of service, loss of business or

anticipated profits or consequential damages; or (iv) the delivery, operation,

servicing, maintenance, repair, improvement or replacement of any Equipment. If

and so long as, no default exists under this Agreement, Lessee shall be, and

hereby is, authorized during the term of this Agreement to assert and enforce

whatever claims and rights Lessor may have against any Supplier of the Equipment

at Lessee's sole cost and expense, in the name of and for the account of Lessor

and/or Lessee, as their interests may appear.

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16. REPRESENTATIONS AND WARRANTIES OF LESSEE: Lessee makes each of the

following representations and warranties to Lessor on the date hereof and on the

date of execution of each Schedule.

(a) Lessee has adequate power and capacity to enter into, and perform

under, this Agreement and all related documents (together, the "DOCUMENTS").

Lessee is duly qualified to do business wherever necessary to carry on its

present business and operations, including the jurisdiction(s) where the

Equipment is or is to be located.

(b) The Documents have been duly authorized, executed and delivered by

Lessee and constitute valid, legal and binding agreements, enforceable in

accordance with their terms, except to the extent that the enforcement of

remedies may be limited under applicable bankruptcy and insolvency laws.

(c) No approval, consent or withholding of objections is required from any

governmental authority or entity with respect to the entry into or performance

by Lessee of the Documents except such as have already been obtained.

(d) The entry into and performance by Lessee of the Documents will not:

(i) violate any judgment, order, law or regulation applicable to Lessee or any

provision of Lessee's Certificate of Incorporation or bylaws; or (ii) result in

any breach of, constitute a default under or result in the creation of any lien,

charge, security interest or other encumbrance upon any Equipment pursuant to

any indenture, mortgage, deed of trust, bank loan or credit agreement or other

instrument (other than this Agreement) to which Lessee is a party.

(e) There are no suits or proceedings pending or threatened in court or

before any commission, board or other administrative agency against or affecting

Lessee, which if decided against Lessee will have a material adverse effect on

the ability of Lessee to fulfill its obligations under this Agreement.

(f) The Equipment accepted under any Certificate of Acceptance is and will

remain tangible personal property.

(g) Each financial statement delivered to Lessor has been prepared in

accordance with generally accepted accounting principles consistently applied.

Since the date of the most recent financial statement, there has been no

material adverse change.

(h) Lessee's exact legal name is as set forth in the first sentence of

this Agreement and Lessee is and will be at all times validly existing and in

good standing under the laws of the State of its incorporation or organization

(specified in the first sentence of this Agreement).

(i) The Equipment will at all times be used for commercial or business

purposes.

17. EARLY TERMINATION:

(a) On or after the First Termination Date (specified in the applicable

Schedule), Lessee may, so long as no default exists hereunder, terminate this

Agreement as to all (but not

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less than all) of the Equipment on such Schedule as of a rent payment date

("TERMINATION DATE"). Lessee must give Lessor at least ninety (90) days prior

written notice of the termination.

(b) Lessee shall, and Lessor may, solicit cash bids for the Equipment on

an AS IS, WHERE IS BASIS without recourse to or warranty from Lessor, express or

implied ("AS IS BASIS"). Prior to the Termination Date, Lessee shall (i) certify

to Lessor any bids received by Lessee and (ii) pay to Lessor (A) the Termination

Value (calculated as of the rent due on the Termination Date) for the Equipment,

and (B) all rent and other sums due and unpaid as of the Termination Date.

(c) If all amounts due hereunder have been paid on the Termination Date,

Lessor shall (i) sell the Equipment on an AS IS BASIS for cash to the highest

bidder and (ii) refund the proceeds of such sale (net of any related expenses)

to Lessee up to the amount of the Termination Value. If such sale is not

consummated, no termination shall occur and Lessor shall refund the Termination

Value (less any expenses incurred by Lessor) to Lessee.

(d) Notwithstanding the foregoing, Lessor may elect by written notice, at

any time prior to the Termination Date, not to sell the Equipment. In that

event, on the Termination Date Lessee shall (i) return the Equipment (in

accordance with Section 10) and (ii) pay to Lessor all amounts required under

Section 17(b) less the amount of the highest bid certified by Lessee to Lessor.

18. PURCHASE OPTION:

(a) Lessee may at lease expiration purchase all (but not less than all) of

the Equipment in any Schedule on an AS IS BASIS for cash equal to its then Fair

Market Value (plus all applicable sales taxes). Lessee must notify Lessor of its

intent to purchase the Equipment in writing at least one hundred eighty (180)

days in advance. If Lessee is in default or if the Lease has already been

terminated Lessee may not purchase the Equipment.

(b) "Fair Market Value" shall mean the price that a willing buyer (who is

neither a lessee in possession nor a used equipment dealer) would pay for the

Equipment in an arm's-length transaction to a willing seller under no compulsion

to sell. In determining the Fair Market Value the Equipment shall be assumed to

be in the condition in which it is required to be maintained and returned under

this Agreement. If the Equipment is installed it shall be valued on an installed

basis. The costs of removal from current location shall not be a deduction from

the value of the Equipment. If Lessor and Lessee are unable to agree on the Fair

Market Value at least one hundred thirty-five (135) days before lease

expiration, Lessor shall appoint an independent appraiser (reasonably acceptable

to Lessee) to determine Fair Market Value. The independent appraiser's

determination shall be final, binding and conclusive. Lessee shall bear all

costs associated with any such appraisal.

(c) Lessee shall be deemed to have waived this option unless it provides

Lessor with written notice of its irrevocable election to exercise the same

within fifteen (15) days after Fair Market Value is told to Lessee.

<PAGE>

19. MISCELLANEOUS:

(a) LESSEE AND LESSOR UNCONDITIONALLY WAIVE THEIR RIGHTS TO A JURY TRIAL

OF ANY CLAIM OR CAUSE OF ACTION BASED UPON OR ARISING OUT OF THIS AGREEMENT, ANY

OF THE RELATED DOCUMENTS, ANY DEALINGS BETWEEN LESSEE AND LESSOR RELATING TO THE

SUBJECT MATTER OF THIS TRANSACTION OR ANY RELATED TRANSACTIONS, AND/OR THE

RELATIONSHIP THAT IS BEING ESTABLISHED BETWEEN LESSEE AND LESSOR. THE SCOPE OF

THIS WAIVER IS INTENDED TO BE ALL ENCOMPASSING OF ANY AND ALL DISPUTES THAT MAY

BE FILED IN ANY COURT. THIS WAIVER IS IRREVOCABLE. THIS WAIVER MAY NOT BE

MODIFIED EITHER ORALLY OR IN WRITING. THE WAIVER ALSO SHALL APPLY TO ANY

SUBSEQUENT AMENDMENTS, RENEWALS, SUPPLEMENTS OR MODIFICATIONS TO THIS AGREEMENT,

ANY RELATED DOCUMENTS, OR TO ANY OTHER DOCUMENTS OR AGREEMENTS RELATING TO THIS

TRANSACTION OR ANY RELATED TRANSACTION. THIS AGREEMENT MAY BE FILED AS A WRITTEN

CONSENT TO A TRIAL BY THE COURT.

(b) The Equipment shall remain Lessor's property unless Lessee purchases

the Equipment from Lessor and until such time Lessee shall only have the right

to use the Equipment as a lessee. Any cancellation or termination by Lessor of

this Agreement, any Schedule, supplement or amendment hereto, or the lease of

any Equipment hereunder shall not release Lessee from any then outstanding

obligations to Lessor hereunder. All Equipment shall at all times remain

personal property of Lessor even though it may be attached to real property. The

Equipment shall not become part of any other property by reason of any

installation in, or attachment to, other real or personal property.

(c) Time is of the essence of this Agreement. Lessor's failure at any time

to require strict performance by Lessee of any of the provisions hereof shall

not waive or diminish Lessor's right at any other time to demand strict

compliance with this Agreement. Lessee agrees, upon Lessor's request, to

execute, or otherwise authenticate, any document, record or instrument necessary

or expedient for filing, recording or perfecting the interest of Lessor or to

carry out the intent of this Agreement. In addition, Lessee hereby authorizes

Lessor to file a financing statement and amendments thereto describing the

Equipment described in any and all Schedules now and hereafter executed pursuant

hereto and adding any other collateral described therein and containing any

other information required by the applicable Uniform Commercial Code. Lessee

irrevocably grants to Lessor the power to sign Lessee's name and generally to

act on behalf of Lessee to execute and file financing statements and other

documents pertaining to any or all of the Equipment. All notices required to be

given hereunder shall be deemed adequately given if sent by registered or

certified mail to the addressee at its address stated herein, or at such other

place as such addressee may have specified in writing. This Agreement and any

Schedule and Annexes thereto constitute the entire agreement of the parties with

respect to the subject matter hereof. NO VARIATION OR MODIFICATION OF THIS

AGREEMENT OR ANY WAIVER OF ANY OF ITS PROVISIONS OR CONDITIONS, SHALL BE VALID

UNLESS IN WRITING AND SIGNED BY AN AUTHORIZED REPRESENTATIVE OF THE PARTIES

HERETO.

<PAGE>

(d) If Lessee does not comply with any provision of this Agreement, Lessor

shall have the right, but shall not be obligated, to effect such compliance, in

whole or in part. All reasonable amounts spent and obligations incurred or

assumed by Lessor in effecting such compliance shall constitute additional rent

due to Lessor. Lessee shall pay the additional rent within five days after the

date Lessor sends notice to Lessee requesting payment. Lessor's effecting such

compliance shall not be a waiver of Lessee's default.

(e) Any rent or other amount not paid to Lessor when due shall bear

interest, from the due date until paid, at the lesser of eighteen percent (18%)

per annum or the maximum rate allowed by law. Any provisions in this Agreement

and any Schedule that are in conflict with any statute, law or applicable rule

shall be deemed omitted, modified or altered to conform thereto.

(f) Lessee hereby irrevocably authorizes Lessor to adjust the Capitalized

Lessor's Cost up or down by no more than ten percent (10%) within each Schedule

to account for equipment change orders, equipment returns, invoicing errors, and

similar matters. Lessee acknowledges and agrees that the rent shall be adjusted

as a result of the change in the Capitalized Lessor's Cost. Lessor shall send

Lessee a written notice stating the final Capitalized Lessor's Cost, if it has

changed.

(g) THIS AGREEMENT AND THE RIGHTS AND OBLIGATIONS OF THE PARTIES HEREUNDER

SHALL IN ALL RESPECTS BE GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH, THE

INTERNAL LAWS OF THE STATE OF CONNECTICUT (WITHOUT REGARD TO THE CONFLICT OF

LAWS PRINCIPLES OF SUCH STATE), INCLUDING ALL MATTERS OF CONSTRUCTION, VALIDITY

AND PERFORMANCE, REGARDLESS OF THE LOCATION OF THE EQUIPMENT.

(h) Any cancellation or termination by Lessor, pursuant to the provisions

of this Agreement, any Schedule, supplement or amendment hereto, of the lease of

any Equipment hereunder, shall not release Lessee from any then outstanding

obligations to Lessor hereunder.

(i) To the extent that any Schedule would constitute chattel paper, as

such term is defined in the Uniform Commercial Code as in effect in any

applicable jurisdiction, no security interest therein may be created through the

transfer or possession of this Agreement in and of itself without the transfer

or possession of the original of a Schedule executed pursuant to this Agreement

and incorporating this Agreement by reference, and no security interest in this

Agreement and a Schedule may be created by the transfer or possession of any

counterpart of the Schedule other than the original thereof; which shall be

identified as the document marked "Original" and all other counterparts shall be

marked "Duplicate".

IN WITNESS WHEREOF, Lessee and Lessor have caused this Agreement to be

executed by their duly authorized representatives as of the date first above

written.

<PAGE>

LESSOR: LESSEE:

GENERAL ELECTRIC CAPITAL CORPORATION PREDIX PHARMACEUTICALS, INC.

By: /s/ JOHN EDEL By: /s/ DALE DHANOA

----------------------------------- ----------------------------

Name: John Edel Name: Dale Dhanoa

Title: Senior Vice President Title: Senior Vice President

<PAGE>

BIOTECH EQUIPMENT SCHEDULE

SCHEDULE NO. 001

DATED THIS 12/30/02

TO MASTER LEASE AGREEMENT

DATED AS OF DECEMBER 3, 2002

LESSOR & MAILING ADDRESS: LESSEE & MAILING ADDRESS:

General Electric Capital Corporation Predix Pharmaceuticals, Inc.

401 Merritt 7 Suite 23 10 K Gill Street

Norwalk, CT 06851-1177 Woburn, MA 01801

This Schedule is executed pursuant to, and incorporates by reference the terms

and conditions of, and capitalized terms not defined herein shall have the

meanings assigned to them in, the Master Lease Agreement identified above

("AGREEMENT" said Agreement and this Schedule being collectively referred to as

"LEASE"). This Schedule, incorporating by reference the Agreement, constitutes a

separate instrument of lease.

A. EQUIPMENT: Subject to the terms and conditions of the Lease, Lessor agrees

to Lease to Lessee the Equipment described below (the "EQUIPMENT").

<TABLE>

<CAPTION>

NUMBER CAPITALIZED

OF UNITS LESSOR'S COST MANUFACTURER SERIAL NUMBER MODEL AND TYPE OF EQUIPMENT

-------- ------------- ------------ ------------- ---------------------------

<S> <C> <C> <C> <C>

1 $243,652.00 Varian, Inc. 310036293 Mercury Plus 400 High

Resolution Console System

</TABLE>

B. FINANCIAL TERMS

1. Advance Rent (if any): $ 6,895.35

2. Capitalized Lessor's Cost: $ 243,652.00

3. Basic Term (No. of Months): 36 MONTHS.

4. Basic Term Lease Rate Factor: 2.829999

5. Basic Term Commencement Date: 1/1/03

6. Lessee Federal Tax ID No.: 04-3585114

7. Last Delivery Date: 12/30/02

8. Daily Lease Rate Factor: .0943

9. First Termination Date: N/A (_____) months after the Basic Term

Commencement Date.

10. Interim Rent: For the period from and including the Lease Commencement

Date to but not including the Basic Term Commencement Date ("Interim

Period"), Lessee shall pay as rent ("Interim Rent") for each unit of

Equipment, the product of the Daily Lease Rate Factor times the

Capitalized Lessor's Cost of such unit times the number of days in the

Interim Period. Interim Rent shall be due on JANUARY 1, 2003.

11. Basic Term Rent. Commencing on 1/1/03 and on the same day of each month

thereafter (each, a "Rent Payment Date") during the Basic Term, Lessee

shall pay as rent ("Basic

<PAGE>

Term Rent") the product of the Basic Term Lease Rate Factor times the

Capitalized Lessor's Cost of all Equipment on this Schedule.

C. TAX BENEFITS Depreciation Deductions:

1. Depreciation method is the 200 % declining balance method, switching to

straight line method for the 1st taxable year for which using the straight line

method with respect to the adjusted basis as of the beginning of such year will

yield a larger allowance, taking into account the 30% special depreciation

allowance and basis adjustment under Section 168(k)(1) of the code.

2. Recovery Period: FIVE (5) YEARS.

3. Basis: 100 % of the Capitalized Lessor's Cost.

D. PROPERTY TAX

PROPERTY TAX NOT APPLICABLE ON EQUIPMENT LOCATED IN MASSACHUSETTS.

Lessor may notify Lessee (and Lessee agrees to follow such notification)

regarding any changes in property tax reporting and payment

responsibilities.

E. ARTICLE 2A NOTICE

IN ACCORDANCE WITH THE REQUIREMENTS OF ARTICLE 2A OF THE UNIFORM

COMMERCIAL CODE AS ADOPTED IN THE APPLICABLE STATE, LESSOR HEREBY MAKES

THE FOLLOWING DISCLOSURES TO LESSEE PRIOR TO EXECUTION OF THE LEASE, (A)

THE PERSON(S) SUPPLYING THE EQUIPMENT IS VARIAN, INC. (THE "SUPPLIER(S)"),

(B) LESSEE IS ENTITLED TO THE PROMISES AND WARRANTIES, INCLUDING THOSE OF

ANY THIRD PARTY, PROVIDED TO THE LESSOR BY SUPPLIER(S), WHICH IS SUPPLYING

THE EQUIPMENT IN CONNECTION WITH OR AS PART OF THE CONTRACT BY WHICH

LESSOR ACQUIRED THE EQUIPMENT AND (C) WITH RESPECT TO SUCH EQUIPMENT,

LESSEE MAY COMMUNICATE WITH SUPPLIER(S) AND RECEIVE AN ACCURATE AND

COMPLETE STATEMENT OF SUCH PROMISES AND WARRANTIES, INCLUDING ANY

DISCLAIMERS AND LIMITATIONS OF THEM OR OF REMEDIES. TO THE EXTENT

PERMITTED BY APPLICABLE LAW, LESSEE HEREBY WAIVES ANY AND ALL RIGHTS AND

REMEDIES CONFERRED UPON A LESSEE IN ARTICLE 2A AND ANY RIGHTS NOW OR

HEREAFTER CONFERRED BY STATUTE OR OTHERWISE WHICH MAY LIMIT OR MODIFY ANY

OF LESSOR'S RIGHTS OR REMEDIES UNDER THE DEFAULT AND REMEDIES SECTION OF

THE AGREEMENT.

<PAGE>

F. STIPULATED LOSS AND TERMINATION VALUE TABLE*

<TABLE>

<CAPTION>

Termination Stipulated Termination Stipulated

Rental Value Loss Value Value Loss Value

Basic Percentage Percentage Rental Percentage Percentage

------ ----------- ---------- ------ ----------- ----------

<S> <C> <C> <C> <C> <C>

1 103.586 107.493 19 65.688 69.389

2 101.835 105.731 20 63.365 67.055

3 99.964 103.849 21 61.026 64.704

4 97.981 101.854 22 58.668 62.336

5 95.978 99.840 23 56.282 59.938

6 93.956 97.806 24 53.877 57.522

7 91.914 95.753 25 51.455 55.088

8 89.847 93.674 26 49.002 52.623

9 87.760 91.576 27 46.519 50.129

10 85.653 89.458 28 44.020 47.618

11 83.520 87.313 29 41.505 45.092

12 81.367 85.148 30 38.975 42.550

13 79.193 82.963 31 36.428 39.992

14 76.992 80.751 32 33.858 37.410

15 74.764 78.511 33 31.263 34.805

16 72.520 76.255 34 28.645 32.175

17 70.259 73.983 35 26.002 29.521

18 67.982 71.695 36 23.337 26.844

</TABLE>

*The Stipulated Loss Value or Termination Value for any unit of Equipment shall

be the Capitalized Lessor's Cost of such unit multiplied by the appropriate

percentage derived from the above table. In the event that the Lease is for any

reason extended, then the last percentage figure shown above shall control

throughout any such extended term.

G. MODIFICATIONS AND ADDITIONS FOR THIS SCHEDULE ONLY

For purposes of this Schedule only, the Agreement is amended as follows:

1. The INDEMNIFICATION Section subsection (b) of the Lease is hereby

amended by deleting the word "and" immediately preceding "(ii)" on the second

line thereof and inserting the following at the end thereof:

; (iii) each item of Equipment constitutes "qualified property" pursuant

to Section 168(k) of the Internal Revenue Code of 1986, as now and

hereafter amended (the "Code"), and is eligible for the additional

first-year depreciation deduction equal to thirty percent (30%) of the

Capitalized Lessor's Cost of the Equipment contemplated by the Code; (iv)

the Equipment shall be treated as originally placed in service not earlier

than the date of the execution and delivery of this Schedule, or in the

event the transaction is a sale-leaseback transaction, Lessee shall not

have placed in service the Equipment subject to this Lease at any time

prior to three months before the execution and delivery of this Schedule;

(v) Lessee has not arranged to purchase, and Lessor is not purchasing the

Equipment pursuant to a binding written contract entered into before

September 11, 2001,

<PAGE>

and (vi) each item of Equipment shall be placed in service before January

1, 2005.

2. The LEASING Section subsection (b) of the Lease is hereby deleted in

its entirety and the following substituted in its stead:

b) The obligation of Lessor to purchase the Equipment from Lessee and to

lease the same to Lessee shall be subject to receipt by Lessor, on or

prior to the earlier of the Lease Commencement Date or Last Delivery Date

therefor, of each of the following documents in form and substance

satisfactory to Lessor: (i) a Schedule for the Equipment (ii) evidence of

insurance which complies with the requirements of the INSURANCE Section of

the Lease, and (iii) such other documents as Lessor may reasonably

request. Once the Schedule is signed, the Lessee may not cancel the Lease.

3. The DELIVERY, USE AND OPERATION Section subsection (a) of the Lease

shall be deleted and the following substituted in its stead:

The parties acknowledge that this is a sale/leaseback transaction and the

Equipment is in Lessee's possession as of the Lease Commencement Date.

4. BILL OF SALE

Lessee, in consideration of the Lessor's payment of the amount set forth

in B 2. above, which includes any applicable sales taxes (which payment Lessee

acknowledges), hereby grants, sells, assigns, transfers and delivers to Lessor

the Equipment along with whatever claims and rights Seller may have against the

manufacturer and/or Supplier of the Equipment, including but not limited to all

warranties and representations. At Lessors request Lessee will cause Supplier to

deliver to Lessor a written statement wherein the Supplier (i) consents to the

assignment to Lessor of whatever claims and rights Lessee may have against the

Supplier, (ii) agrees not to retain any security interest, lien or other

encumbrance in or upon the Equipment at any time, and to execute such documents

as Lessor may request to evidence the release of any such encumbrance, and (iii)

represents and warrants to Lessor (x) that Supplier has previously conveyed full

title to the Equipment to Lessee, (y) that the Equipment was delivered to Lessee

and installation completed, and (z) that the final purchase price of the

Equipment (or a specified portion of such purchase price) has been paid by

Lessee.

Lessor is purchasing the Equipment for leasing back to Lessee pursuant to

the Lease. Lessee represents and warrants to Lessor that (i) Lessor will acquire

by the terms of this Bill of Sale good title to the Equipment free from all

liens and encumbrances whatsoever; (ii) Lessee has the right to sell the

Equipment; and (iii) the Equipment has been delivered to Lessee in good order

and condition, and conforms to the specifications, requirements and standards

applicable thereto; and (iv) the equipment has been accurately labeled,

consistent with the requirements of 40 CFR part 82 Subpart E, with respect to

products manufactured with a controlled (ozone-depleting) substance.

Lessee agrees to save and hold harmless Lessor from and against any and

all federal, state, municipal and local license fees and taxes of any kind or

nature, including, without limiting the generality of the foregoing, any and all

excise, personal property, use and sales taxes, and

<PAGE>

from and against any and all liabilities, obligations, losses, damages,

penalties, claims, actions and suits resulting therefrom and imposed upon,

incurred by or asserted against Lessor as a consequence of the sale of the

Equipment to Lessor.

5. ACCEPTANCE

Pursuant to the provisions of the Lease, as it relates to this Schedule,

Lessee hereby certifies and warrants that (i) all Equipment listed above has

been delivered and installed (if applicable); (ii) Lessee has inspected the

Equipment, and all such testing as it deems necessary has been performed by

Lessee, Supplier or the manufacturer; and (iii) Lessee accepts the Equipment for

all purposes of the Lease, the purchase documents and all attendant documents.

Lessee does further certify that as of the date hereof (i) Lessee is not

in default under the Lease; (ii) the representations and warranties made by

Lessee pursuant to or under the Lease are true and correct on the date hereof

and (iii) Lessee has reviewed and approves of the purchase documents for the

Equipment, if any.

6. EQUIPMENT SPECIFIC PROVISIONS

The MAINTENANCE Section of the Lease is amended by adding the following as

the fifth sentence in subsection (a):

Lessee agrees that upon return of the Equipment, it will comply with all

original manufacturer's performance specifications for new Equipment without

expense to Lessor. Lessee shall, if requested by Lessor, obtain a certificate or

service report from the manufacturer attesting to such condition.

Each reference contained in this Agreement to:

(a) "Adverse Environmental Condition" shall refer to (i) the existence or the

continuation of the existence, of an Environmental Emission (including, without

limitation, a sudden or non-sudden accidental or non-accidental Environmental

Emission), of, or exposure to, any substance, chemical, material, pollutant,

Contaminant, odor or audible noise or other release or emission in, into or onto

the environment (including, without limitation, the air, ground, water or any

surface) at, in, by, from or related to any Equipment, (ii) the environmental

aspect of the transportation, storage, treatment or disposal of materials in

connection with the operation of any Equipment or (iii) the violation, or

alleged violation of any statutes, ordinances, orders, rules regulations,

permits or licenses of, by or from any governmental authority, agency or court

relating to environmental matters connected with any Equipment.

(b) "Affiliate" shall refer, with respect to any given Person, to any Person

that directly or indirectly through one or more intermediaries, controls, or is

controlled by, or is under common control with, such Person.

(c) "Contaminant" shall refer to those substances which are regulated by or form

the basis of liability under any Environmental Law, including, without

limitation, asbestos, polychlorinated biphenyls ("PCB's"), and radioactive

substances, or other material or substance which has in the

<PAGE>

past or could in the future constitute a health, safety or environmental hazard

to any Person, property or natural resources.

(d) "Environmental Claim" shall refer to any accusation, allegation, notice of

violation, claim, demand, abatement or other order on direction (conditional or

otherwise) by any governmental authority or any Person for personal injury

(including sickness, disease or death), tangible or intangible property damage,

damage to the environment or other adverse effects on the environment, or for

fines, penalties or restrictions, resulting from or based upon any Adverse

Environmental Condition.

(e) "Environmental Emission" shall refer to any actual or threatened release,

spill, emission, leaking, pumping, injection, deposit, disposal, discharge,

dispersal, leaching or migration into the indoor or outdoor environment, or into

or out of any of the Equipment, including, without limitation, the movement of

any Contaminant or other substance through or in the air, soil, surface water,

groundwater or property.

(f) "Environmental Law" shall mean any federal, foreign, state or local law,

rule or regulation pertaining to the protection of the environment, including,

but not limited to, the Comprehensive Environmental Response, Compensation, and

Liability Act ("CERCLA") (42 U.S.C. Section 9601 et seq.), the Hazardous

Material Transportation Act (49 U.S.C. Section 1801 et seq .), the Federal Water

Pollution Control Act (33 U.S.C. Section 1251 et seq .), the Resource

Conservation and Recovery Act (42 U.S.C. Section 6901 et seq .), the Clean Air

Act (42 U.S.C. Section 7401 et seq .), the Toxic Substances Control Act (15

U.S.C. Section 2601 et seq .), the Federal Insecticide, Fungicide, and

Rodenticide Act (7 U.S.C. Section 1361 et seq .), and the Occupational Safety

and Health Act (19 U.S.C. Section 651 et seq .), as these laws have been amended

or supplemented, and any analogous foreign, federal, state or local statutes,

and the regulations promulgated pursuant thereto.

(g) "Environmental Loss" shall mean any loss, cost, damage, liability,

deficiency, fine, penalty or expense (including, without limitation, reasonable

attorneys' fees, engineering and other professional or expert fees),

investigation, removal, cleanup and remedial costs (voluntarily or involuntarily

incurred) and damages to, loss of the use of or decrease in value of the

Equipment arising out of or related to any Adverse Environmental Condition.

(h) "Person" shall include any individual, partnership, corporation, trust,

unincorporated organization, government or department or agency thereof and any

other entity.

Lessee shall fully and promptly pay, perform, discharge, defend, indemnify and

hold harmless Lessor and its Affiliates, successors and assigns, directors,

officers, employees and agents from and against any Environmental Claim or

Environmental Loss.

The provisions of this Schedule shall survive any expiration or termination of

the Lease and shall be enforceable by Lessor, its successors and assigns.

The MAINTENANCE Section subsection (a) of the Lease shall be amended by adding

the following at the end thereof:

<PAGE>

RETURN PROVISIONS: In addition to the provisions provided for in the RETURN OF

EQUIPMENT Section of the Lease, and provided that Lessee has elected not to

exercise its option to purchase the Equipment Lessee shall, at its expense:

(a) at least one hundred eighty (180) days and not more than two hundred seventy

(270) days prior to expiration or earlier termination of the Lease, provide to

Lessor a detailed inventory of all components of the Equipment. The inventory

should include, but not be limited to, a listing of model and serial numbers for

all components comprising the Equipment;

(b) at least one hundred eighty (180) days prior to expiration or earlier

termination of the Lease, with reference to computer based equipment comprising

the Equipment, provide to Lessor a detailed listing of all internal circuit

boards by both the model and serial number for all hardware comprising the

Equipment and a listing of all software features listed individually;

(c) at least one hundred eighty (180) days prior to expiration or earlier

termination of the Lease, upon receiving reasonable notice from Lessor, provide

or cause the vendor(s) or manufacturer(s) to provide to Lessor the following

documents: (i) one set of service manuals, and operating manuals including

replacements and/or additions thereto, such that all documentation is completely

up-to-date; (ii) one set of documents, detailing equipment configuration,

operating requirements, maintenance records, and other technical data concerning

the set-up and operation of the Equipment, including replacements and/or

additions thereto, such that all documentation is completely up-to-date;

(d) at least one hundred eighty (180) days prior to expiration or earlier

termination of the Lease, upon receiving reasonable notice from Lessor, make the

Equipment available for on-site operational inspections by potential purchasers,

under power, and provide personnel, power and other requirements necessary to

demonstrate electrical and mechanical systems for each item of the Equipment;

(e) at least one hundred eighty (180) days prior to expiration or earlier

termination of the Lease, cause manufacturer's representative or qualified

equipment maintenance provider, acceptable to Lessor, (the "Authorized

Inspector") to perform a comprehensive physical inspection, including testing

all material and workmanship of the Equipment and ensure all Equipment and

equipment operations conform to all applicable local, state, and federal laws,

health and safety guidelines including the then current FDA regulations; and if

during such inspection, examination and test, the Authorized Inspector finds any

of the material or workmanship to be defective or the Equipment not operating

within manufacturer's specifications and the then current FDA regulations, then

Lessee shall repair or replace such defective material and, after corrective

measures are completed, Lessee will provide for a follow-up inspection of the

Equipment by the Authorized Inspector as outlined in the preceding clause;

(f) have each item of Equipment returned with an in-depth field service report

detailing said inspection as outlined in Section (e) above. The report shall

certify that the Equipment has been properly inspected, examined and tested and

is operating within the manufacturer's specifications;

<PAGE>

(g) provide that all Equipment will be cleaned and cosmetically acceptable, and

in such condition so that it may be im


 
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