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ALTON PLAZA FIFTH AMENDMENT TO LEASE

Lease Agreement

ALTON PLAZA FIFTH AMENDMENT TO LEASE | Document Parties: Aetna Life Insurance Company | ALTON PLAZA PROPERTY, INC | Asset Management | ISTA PHARMACEUTICALS, INC You are currently viewing:
This Lease Agreement involves

Aetna Life Insurance Company | ALTON PLAZA PROPERTY, INC | Asset Management | ISTA PHARMACEUTICALS, INC

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Title: ALTON PLAZA FIFTH AMENDMENT TO LEASE
Date: 8/21/2007
Industry: Biotechnology and Drugs     Sector: Healthcare

ALTON PLAZA FIFTH AMENDMENT TO LEASE, Parties: aetna life insurance company , alton plaza property  inc , asset management , ista pharmaceuticals  inc
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Exhibit 10.1

ALTON PLAZA

FIFTH AMENDMENT TO LEASE

( Expansion of Premises; Extension of Term )

THIS FIFTH AMENDMENT TO LEASE (this “Amendment”) dated for reference purposes only as of July 25, 2007, is entered into by and between ALTON PLAZA PROPERTY, INC., a Delaware corporation (“Lessor” or “Landlord”), and ISTA PHARMACEUTICALS, INC., a Delaware corporation (“Lessee” or “Tenant”).

RECITALS

A. Lessor’s predecessor in interest, Aetna Life Insurance Company, and Lessee entered into that certain Lease Agreement dated September 13, 1996 (the “Original Lease”) for certain premises located at 15279 Alton Parkway, Suite 100, Irvine, California 92618 (the “Existing Premises”), which are located in the industrial complex commonly known as Alton Plaza Industrial Park (the “Park”). The Existing Premises contain approximately 13,448 square feet. Landlord and Tenant entered into that certain First Amendment to Lease dated as of June 27, 2001 (the “First Amendment”), that certain Second Amendment to Lease dated as of February 13, 2002 (the “Second Amendment”), that certain Third Amendment to lease dated as of August 12, 2004 (the “Third Amendment”), that certain Addendum to Third Amendment to Lease dated as of September 15, 2004 (the “Third Addendum”), and that certain Fourth Amendment to Lease dated as of August 31, 2005 (the “Fourth Amendment”).

B. Pursuant to the Third Amendment, the New Premises (located in the building commonly known as 15295 Alton Parkway, as more specifically described in the Third Amendment) were added to the Existing Premises. The Existing Premises and the New Premises are hereinafter referred to collectively as the “Original Premises”. The New Expiration Date for the Original Premises is October 31, 2009.

C. Pursuant to the Fourth Amendment, the 15273 Premises (located in the building commonly known as 15273 Alton Parkway, as more specifically described in the Fourth Amendment) were added to the Original Premises. The 15273 Premises Expiration Date for the 15273 Premises is March 31, 2016. The Original Premises and the 15273 Premises are hereinafter referred to collectively as the “Current Premises”.

D. The Original Lease as amended by the First Amendment, the Second Amendment, the Third Amendment, the Third Addendum and the Fourth Amendment is hereinafter referred to as the “Lease”.

E. Landlord and Tenant presently desire to amend the Lease to, inter alia, provide for the addition of certain additional premises to the Lease.

NOW, THEREFORE, in consideration of the mutual covenants and conditions contained herein and other good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged, the parties hereto agree as follows:

1. Definitions . Unless otherwise specifically set forth herein, all capitalized terms used herein shall have the same meanings as set forth in the Lease.

 


2. Addition of the 15285 Premises . The increment of space located at 15285 Alton Parkway, commonly known as Suite 100 and labeled “15285 Premises” on the attached Exhibit A-5 shall be added to the Premises covered by the Lease as provided herein. Landlord and Tenant agree that initially for the purpose of the Lease and this Amendment, the 15285 Premises shall be deemed to contain approximately 8,181 square feet of space. The term of the Lease with respect to the 15285 Premises shall commence on the 15285 Commencement Date (as defined below). As used herein, the “15285 Commencement Date” shall mean December 12, 2007; provided, however, that if Landlord does not regain possession of the 15285 Premises from the Prior Tenant (as defined below) by October 1, 2007, then the 15285 Commencement Date shall be the date which is seventy-three (73) days after Landlord regains possession of the 15285 Premises from Prior Tenant. Landlord shall tender possession of the 15285 Premises to Tenant following Substantial Completion of the 15285 Work (as defined below). The 15285 Premises shall become part of the “Premises” on the 15285 Commencement Date and shall remain a portion of the “Premises” throughout the 15285 Term (as defined below). As of the 15285 Commencement Date, the Basic Lease Information Page of the Lease shall be modified to provide that the “Premises” consists of approximately 52,920 square feet (the combined 15285 Premises and the Current Premises). The parties hereto acknowledge that the 15285 Premises are currently occupied by a third party (“Prior Tenant”) and that the lease with respect to the 15285 Premises is scheduled to expire on September 30, 2007. Landlord agrees to use diligent and commercially reasonable efforts to cause the current occupant of the 15285 Premises to vacate its premises on or before September 30, 2007. If for any reason Landlord cannot or does not deliver possession of the 15285 Premises to Tenant on or before September 30, 2007, the 15285 Commencement Date shall be extended by one day for each day beyond September 30, 2007 that Landlord fails to deliver possession of the 15285 Premises to Tenant. If Landlord shall not have tendered possession of the 15285 Premises to Tenant on or before November 15, 2007, Tenant may, at Tenant’s option, by notice in writing to Landlord terminate this Amendment and receive a refund of the additional security deposit described in Section 21, below and any prepaid rent. If Tenant terminates this Amendment as provided in the preceding sentence, the parties shall be discharged from all obligations under this Amendment, except that Landlord shall return any money previously deposited with Landlord by Tenant. Landlord shall commence the 15285 Work promptly following the vacation of the 15285 Premises by the current occupant thereof. Notwithstanding anything to the contrary contained in this Section 2, if the Prior Tenant has not vacated the 15285 Premises by December 31, 2007 (the “Trigger Date”), Tenant shall have the right to terminate this Amendment within ten (10) days following the Trigger Date, time being of the essence herein. If Tenant timely terminates this Amendment as provided in the preceding sentence, the parties shall be discharged from all obligations under this Amendment accruing on and after the effective date of such termination, except that Landlord shall return any money previously deposited with Landlord by Tenant in connection with this Amendment including the additional Security Deposit referenced in Section 21 below.

3. Planning Work .

3.1 Architect . The architect for the 15285 Work shall be H. Hendy Associates or such other architect selected by Tenant and approved by Landlord (such approval not to be unreasonably withheld) (the “Architect”). The parties acknowledge that Tenant has already engaged Architect to perform certain preliminary design work in connection with the proposed 15285 Work (as defined in Section 3.3 below), the cost of which shall be included in Total Construction Costs (as defined below). Within three (3) business days following the full execution of this Amendment by Landlord and Tenant, Tenant shall meet with the Architect to discuss its program and facility requirements (the “Program”) for the 15285 Premises and the nature and extent of all improvements

 

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that Tenant proposes to install in the 15285 Premises and at such meeting, shall provide the Architect with all necessary data and information requested by the Architect to prepare initial Program documents and then space plans therefor as required by this Section 3.

3.2 Preparation and Delivery of 15285 Space Plan . On or before September 7, 2007, Tenant shall cause the Architect to deliver to Landlord a pricing plan prepared by the Architect depicting improvements to be installed in the 15285 Premises sufficient for preliminary pricing (the “15285 Space Plan”). On or before the expiration of ten (10) business days from its receipt of the 15285 Space Plan, Landlord shall deliver to Tenant (i) a preliminary cost estimate to complete the work depicted in the 15285 Space Plan (the “15285 Budget”), (ii) a preliminary project schedule (the “15285 Project Schedule”), and (iii) the Contractor’s general conditions and fee bid as described in Section 4.1 below. Tenant shall notify Landlord whether it approves of the scope of the 15285 Work outlined in the submitted 15285 Budget and Project Schedule within five (5) business days after its receipt thereof. If Tenant disapproves of the scope of the 15285 Work outlined in the submitted 15285 Budget and/or Project Schedule within such five (5)-business day period, then Tenant shall notify Landlord thereof specifying in reasonable detail the reasons for such disapproval, in which case Landlord shall within three (3) business days after such notice or such longer period as reasonably necessary to revise the scope of work, revise such 15285 Budget and/or Project Schedule, as the case may be, in accordance with Tenant’s objections and submit the revised 15285 Budget and/or Project Schedule, as the case may be, to Tenant for its review and approval. Tenant shall notify Landlord in writing whether it approves of the scope of the 15285 Work outlined in the resubmitted 15285 Budget and/or Project Schedule, as the case may be, within five (5) business days after its receipt thereof. This process shall be repeated until the 15285 Budget and Project Schedule have been finally approved by Tenant and Landlord. If Tenant fails to notify Landlord that it disapproves of the initial 15285 Budget and/or Project Schedule within five (5) business days (or, in the case of a resubmitted 15285 Budget and/or Project Schedule within five (5)business days after the submission thereof), then Tenant shall be deemed to have approved the 15285 Budget and/or Project Schedule in question. Notwithstanding such approval, the parties hereto acknowledge that the 15285 Budget and 15285 Project Schedule may be subject to revision pending approval of the 15285 Working Drawings as described in Section 3.3 below.

3.3 15285 Working Drawings . Within twenty (20) business days of the approval of the 15285 Budget, 15285 Project Schedule and selection of the Contractor (as defined below) for the 15285 Work, Landlord shall cause the Architect to prepare final working drawings of all improvements to be installed in the 15285 Premises based on the approved 15285 Space Plan and deliver the same to Tenant for its review and approval (which approval shall not be unreasonably withheld, delayed or conditioned); such 20-business day period shall be extended due to any delays in the Architect’s preparation of same which is outside of Landlord’s control. Such 15285 Working Drawings shall be prepared by the Architect (and if necessary, engineers), whose fees shall be included in the Total Construction Costs (as defined below). Tenant shall notify Landlord whether it approves of the submitted 15285 Working Drawings within two (2) business days after Landlord’s submission thereof. If Tenant disapproves of such 15285 Working Drawings, then Tenant shall notify Landlord thereof specifying in reasonable detail the reasons for such disapproval, in which case Landlord shall, within three (3) business days after such notice or such longer period as reasonably necessary, revise such 15285 Working Drawings in accordance with Tenant’s objections and submit the revised 15285 Working Drawings to Tenant for its review and approval. Tenant shall notify Landlord in writing whether it approves of the resubmitted 15285 Working Drawings within one (1) business day after its receipt thereof. This process shall be repeated until the working drawings have been finally approved by Landlord and Tenant. If Tenant fails to notify Landlord that

 

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it disapproves of the initial 15285 Working Drawings within three (3) business days (or, in the case of resubmitted working drawings, within one (1) business day) after the submission thereof, then Tenant shall be deemed to have approved the working drawings in question. Any delay caused by Tenant’s failure to respond within the time periods set forth in this Section 3.3 as to such 15285 Working Drawings shall constitute a Tenant Delay (defined below). As used herein, “15285 Working Drawings” shall mean the final 15285 Working Drawings approved by Landlord and Tenant, as amended from time to time by any changes thereto approved by Landlord and Tenant, and “15285 Work” shall mean all improvements to be constructed in the 15285 Premises in accordance with and as indicated on the 15285 Working Drawings. The 15285 Work shall not include any alterations, additions or improvements installed or constructed by Tenant or any of Tenant’s trade fixtures, equipment, furniture, furnishings, telephone equipment or other personal property. Upon Tenant’s written request at the time it seeks Landlord’s approval of the 15285 Working Drawings, Landlord agrees to indicate in writing whether it will require any elements of the 15285 Work to be removed from the 15285 Premises upon the expiration or earlier termination of the Lease. Landlord’s approval of the 15285 Working Drawings shall not be a representation or warranty of Landlord that such drawings are adequate for any use or comply with any law, but shall merely be the consent of Landlord thereto. Tenant shall, at Landlord’s request, sign the 15285 Working Drawings to evidence its review and approval thereof. After the 15285 Working Drawings have been approved, Landlord shall cause the 15285 Work to be performed in accordance with the 15285 Working Drawings. Landlord shall cause the Contractor to construct the 15285 Work to comply with the 15285 Working Drawings and Legal Requirements.

3.4 15285 Budget . Upon approval of the 15285 Working Drawings by Tenant and Landlord, and subject to the provisions of Section 3.3 above, Landlord shall cause the Contractor to submit the 15285 Work for bid by all necessary subcontractors in accordance with the provisions of Section 4.2. Upon selection of the subcontractors, Landlord shall provide to Tenant, prior to commencement of construction of the 15285 Work, a complete budget (the “15285 Final Budget”) showing all line items of the 15285 Work and the schedule of distribution of the Construction Allowance (as defined below) with respect to the 15285 Work. Tenant shall approve or disapprove the 15285 Final Budget within five (5) business days of receipt, such approval not to be unreasonably conditioned or withheld. If Tenant fails to notify Landlord that it disapproves of the 15285 Final Budget within such five (5) business-day period, then Tenant shall be deemed to have approved the 15285 Final Budget.

4. Selection of General Contractor/Subcontractors .

4.1 15285 Work . Within ten (10) business days of receipt of the 15285 Space Plan, Landlord shall seek competitive bids from DPR Construction, Howard Building Corporation, ROEL Construction and Caliber Construction, or such other qualified contractor as mutually agreed to by Landlord and Tenant for the general conditions and fees each would charge for the cost of constructing the 15285 Work. At the completion of the bidding process, Landlord shall submit to Tenant copies of all bids received. Landlord and Tenant shall select the general contractor to perform the 15285 Work. Landlord and Tenant shall make such selection based on the following criteria: (i) lowest qualified general conditions and fee to complete the 15285 Work, (ii) completion schedule, (iii) the reputation and experience of the contractor’s specific team assembled for this project, and in constructing the type of improvements which Tenant contemplates installing in the 15285 Premises, (iv) Tenant’s prior experience with such general contractor and providing first-class materials, and (v) Landlord’s prior experience with such general contractor in providing first class materials and/or service to the Park. The contractor selected is hereinafter referred to as the “Contractor”.

 

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4.2 Subcontractor Bids . Upon approval of the 15285 Working Drawings, Landlord shall cause the Contractor to submit the 15285 Working Drawings for competitive bidding to qualified subcontractors approved by Landlord, Tenant and Contractor based on the reputation and experience of each subcontractor in constructing the type of improvements which Tenant contemplates installing in the 15285 Premises, Tenant’s, Landlord’s and the Contractor’s prior experience with such subcontractor(s) in providing first class materials and its experience in connection with the installation of the specified items. At the completion of the bidding process, the Contractor shall submit to Landlord and Tenant copies of all subcontractors’ bids received


 
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