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SECOND AMENDED AND RESTATED INVESTOR RIGHTS AGREEMENT

Investors Rights Agreement

SECOND AMENDED AND RESTATED INVESTOR RIGHTS AGREEMENT | Document Parties: GP STRATEGIES CORPORATION | PALADIN LABS INC | Pequot Capital Management, Inc | SMH HYDRO MED II LLC | SMH HYDRO MED LLC | SMH Life Sciences Management, LLC | SMH VALERA LLC | SMM Corporate Management, LLC | VALERA PHARMACEUTICALS, INC | Wheatley Medtech Partners LLC | Wheatley Partners III, LLC You are currently viewing:
This Investors Rights Agreement involves

GP STRATEGIES CORPORATION | PALADIN LABS INC | Pequot Capital Management, Inc | SMH HYDRO MED II LLC | SMH HYDRO MED LLC | SMH Life Sciences Management, LLC | SMH VALERA LLC | SMM Corporate Management, LLC | VALERA PHARMACEUTICALS, INC | Wheatley Medtech Partners LLC | Wheatley Partners III, LLC

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Title: SECOND AMENDED AND RESTATED INVESTOR RIGHTS AGREEMENT
Governing Law: Delaware     Date: 3/14/2005
Industry: Biotechnology and Drugs     Sector: Healthcare

SECOND AMENDED AND RESTATED INVESTOR RIGHTS AGREEMENT, Parties: gp strategies corporation , paladin labs inc , pequot capital management  inc , smh hydro med ii llc , smh hydro med llc , smh life sciences management  llc , smh valera llc , smm corporate management  llc , valera pharmaceuticals  inc , wheatley medtech partners llc , wheatley partners iii  llc
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Exhibit 4.2

VALERA PHARMACEUTICALS, INC.

SECOND AMENDED AND RESTATED INVESTOR RIGHTS AGREEMENT

AUGUST 16, 2004

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TABLE OF CONTENTS

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PAGE

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SECTION 1 GENERAL...................................................... 1

1.1 Definitions.................................................. 1

SECTION 2 RESTRICTIONS ON TRANSFER; REGISTRATION....................... 4

2.1 Restrictions on Transfer..................................... 4

2.2 Demand Registration.......................................... 5

2.3 Piggyback Registrations...................................... 6

2.4 Form S-2 and S-3 Registration................................ 7

2.5 Expenses of Registration..................................... 9

2.6 Obligations of the Company................................... 9

2.7 Termination of Registration Rights........................... 11

2.8 Delay of Registration; Furnishing Information................ 11

2.9 Indemnification.............................................. 11

2.10 Assignment of Registration Rights............................ 13

2.11 Amendment of Registration Rights............................. 14

2.12 Limitation on Subsequent Registration Rights................. 14

2.13 "Market Stand-Off" Agreement................................. 14

2.14 Agreement to Furnish Information............................. 14

2.15 Rule 144 Reporting........................................... 15

SECTION 3 COVENANTS.................................................... 15

3.1 Basic Financial Information and Reporting.................... 15

3.2 Inspection Rights............................................ 16

3.3 Confidentiality of Records................................... 16

3.4 Reservation of Common Stock.................................. 16

3.5 Stock Vesting................................................ 17

3.6 Special Relationships of Prospective Employees............... 17

3.7 Directors' Liability and Indemnification..................... 17

3.8 Reimbursement of Expenses.................................... 17

3.9 Qualified Small Business..................................... 17

3.10 Election of Directors........................................ 17

3.12 Observer Rights.............................................. 18

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3.13 Termination of Covenants..................................... 18

SECTION 4 PREEMPTIVE RIGHTS............................................ 19

4.1 Subsequent Offerings......................................... 19

4.2 Exercise of Preemptive Rights................................ 19

4.3 Termination and Waiver of Preemptive Right................... 19

4.4 Transfer of Preemptive Rights................................ 19

4.5 Excluded Securities.......................................... 20

SECTION 5 MISCELLANEOUS................................................ 20

5.1 Governing Law................................................ 20

5.2 Survival..................................................... 20

5.3 Successors and Assigns....................................... 21

5.4 Entire Agreement............................................. 21

5.5 Severability................................................. 21

5.6 Amendment and Waiver......................................... 21

5.7 Delays or Omissions.......................................... 22

5.8 Notices...................................................... 22

5.9 Attorneys' Fees.............................................. 22

5.10 Titles and Subtitles......................................... 22

5.11 Additional Investors......................................... 22

5.12 Counterparts................................................. 23

5.13 Joinder of Spouses........................................... 23

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VALERA PHARMACEUTICALS, INC.

SECOND AMENDED AND RESTATED INVESTOR RIGHTS AGREEMENT

This SECOND AMENDED AND RESTATED INVESTOR RIGHTS AGREEMENT (this

"Agreement") is entered into as of August 16, 2004, by and among VALERA

PHARMACEUTICALS, INC., a Delaware corporation (the "Company"), the stockholders

of the Company listed as "Common Stock Investors" on EXHIBIT A hereto

(collectively, the "Common Stock Investors", and each individually, a "Common

Stock Investor"), the investors listed as the "Series C Investors" on EXHIBIT A

hereto (the "Series C Investors"), the stockholders of the Company listed as

"Series A Investors" on EXHIBIT A hereto (the "Series A Investors"), and the

stockholders of the Company listed as "Series B Investors" on EXHIBIT A hereto

(the "Series B Investors" and, together with the Common Stock Investors, the

Series C Investors and the Series A Investors, the "Investors").

RECITALS

The Series C Investors are purchasing shares of the Company's Series C

Convertible Preferred Stock pursuant to that certain Stock Purchase Agreement

(the "Purchase Agreement") of even date herewith (the "Financing").

The obligations in the Purchase Agreement are conditioned upon the

execution and delivery of this Agreement.

In connection with the consummation of the Financing, the parties desire to

enter into this Agreement in order to grant registration, information rights and

other rights to the Investors as set forth below.

AGREEMENT

In consideration of the premises and for other good and valuable

consideration, the receipt and sufficiency of which are hereby acknowledged,

intending to be legally bound hereby, the parties agree as follows:

1. GENERAL.

1.1. DEFINITIONS. As used in this Agreement the following terms shall

have the following respective meanings:

"Board of Directors" means the Company's Board of Directors.

"Certificate" means the Company's Restated Certificate of

Incorporation, as filed with the Delaware Secretary of State on August 16, 2004.

"Common Stock" means the Company's common stock, par value $.001 per

share.

"Equity Securities" means (i) any Common Stock, Preferred Stock, or

other security of the Company, (ii) any security convertible, with or without

consideration, into any

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Common Stock, Preferred Stock, or other security of the Company (including any

option to purchase such a convertible security), (iii) any security carrying any

warrant or right to subscribe to or purchase any Common Stock, Preferred Stock,

or other security of the Company, or (iv) any such warrant or right.

"Exchange Act" means the Securities Exchange Act of 1934, as amended.

"Form S-2" means such form under the Securities Act as in effect on

the date hereof or any successor or similar registration form under the

Securities Act subsequently adopted by the SEC that permits inclusion or

incorporation of certain information by reference to other documents filed by

the Company with the SEC.

"Form S-3" means such form under the Securities Act as in effect on

the date hereof or any successor or similar registration form under the

Securities Act subsequently adopted by the SEC, which permits inclusion or

incorporation of substantial information by reference to other documents filed

by the Company with the SEC.

"GP Strategies" means GP Strategies Corporation, a Delaware

corporation.

"Holder" means any person owning of record Registrable Securities, or

securities convertible into Registrable Securities that have not been sold to

the public or any assignee of record of such Registrable Securities or

securities in accordance with Section 2.10 hereof.

"Preferred Stock" means the Company's preferred stock, par value $.001

per share.

"Qualified Offering" means a firm commitment underwritten public

offering of the Company's Common Stock, pursuant to an effective registration

statement under the Securities Act (i) at a public offering price per share,

before deductions for underwriter discounts and commissions, of at least three

(3) times the highest of the original purchase prices of the Series C

Convertible Preferred Stock, Series B Convertible Preferred Stock or Series A

Convertible Preferred Stock (subject to adjustment for any stock splits,

dividends, combinations, recapitalizations and the like), and (ii) with

aggregate proceeds to the Company of at least $25,000,000 before deductions for

underwriter discounts and commissions and any and all expenses of such

underwritten offering incurred by the Company.

"Register," "registered," and "registration" refer to a registration

effected by preparing and filing a registration statement in compliance with the

Securities Act, and the declaration or ordering of effectiveness of such

registration statement or document.

"Registrable Securities" means (a) Common Stock of the Company issued

or issuable upon conversion of the Shares, (b) for purposes of Section 2.3 and

2.4 only (and to the extent such provisions relate to Section 2.3 or 2.4,

Sections 2.1, 2.5, 2.6, 2.7, 2.8, 2.9, 2.10, 2.11, 2.12, 2.13, 2.14, 2.15 or

Section 5), Common Stock owned by GP Strategies, and (c) any Common Stock of the

Company issued as (or issuable upon the conversion or exercise of any warrant,

right or other security which is issued as) a dividend or other distribution

with respect to, or in exchange for or in replacement of, such above-described

securities. Notwithstanding the foregoing, Registrable Securities shall not

include any securities sold by a person to the public

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either pursuant to a registration statement or Rule 144 or sold in a private

transaction in which the transferor's rights under Section 2 of this Agreement

are not assigned.

"Registrable Securities then outstanding" shall be the number of

shares determined by calculating the total number of shares of the Company's

Common Stock that are Registrable Securities and either (a) are then issued and

outstanding or (b) are issuable pursuant to then exercisable or convertible

securities, excluding any Registrable Securities as to which the rights under

Section 2 have terminated pursuant to Section 2.7.

"Registration Expenses" mean all expenses incurred by the Company in

complying with Sections 2.2, 2.3 and 2.4 hereof, including, without limitation,

all registration and filing fees, printing expenses, fees and disbursements of

counsel for the Company, reasonable fees and disbursements of a single special

counsel for the Holders, blue sky fees and expenses and the expense of any

special audits incident to or required by any such registration (but excluding

the compensation of regular employees of the Company which shall be paid in any

event by the Company).

"SEC" or "Commission" means the Securities and Exchange Commission.

"Securities Act" means the Securities Act of 1933, as amended.

"Selling Expenses" mean all underwriting discounts and selling

commissions applicable to the sale.

"Series A Convertible Preferred Stock" means shares of the Company's

Preferred Stock designated as Series A Convertible Preferred Stock, par value

$.001 per share.

"Series B Convertible Preferred Stock" means shares of the Company's

Preferred Stock designated as Series B 10% Convertible Preferred Stock, par

value $.001 per share.

"Series C Convertible Preferred Stock" means shares of the Company's

Preferred Stock designated as Series C Convertible Preferred Stock, par value

$.001 per share.

"Shares" mean (i) Series C Convertible Preferred Stock issued pursuant

to the Purchase Agreement held by the Series C Investors hereto and their

permitted assigns, (ii) Series B Convertible Preferred Stock held by the Series

B Investors and their permitted assigns, (iii) Series A Convertible Preferred

Stock held by the Series A Investors and their permitted assigns, and (iv) for

purposes of Section 2.3 and 2.4 only (and to the extent such provisions relate

to Section 2.3 or 2.4, Sections 2.1, 2.5, 2.6, 2.7, 2.8, 2.9, 2.10, 2.11, 2.12,

2.13 and 2.14 or Section 5), shares of Common Stock held by GP Strategies and

its permitted assigns.

"Special Registration Statement" means a registration statement

relating to any employee benefit plan or with respect to any corporate

reorganization or other transaction under Rule 145 of the Securities Act.

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2. RESTRICTIONS ON TRANSFER; REGISTRATION.

2.1. RESTRICTIONS ON TRANSFER.

(A) Each Holder agrees not to make any disposition of all or any

portion of the Shares or Registrable Securities unless and until:

(I) There is then in effect a registration statement under

the Securities Act covering such proposed disposition and such disposition is

made in accordance with such registration statement; or

(II) (A) The transferee has agreed in writing to be bound by

the terms of this Agreement, (B) such Holder shall have notified the Company of

the proposed disposition and shall have furnished the Company with a detailed

statement of the circumstances surrounding the proposed disposition, and (C) if

reasonably requested by the Company, such Holder shall have furnished the

Company with an opinion of counsel, reasonably satisfactory to the Company, that

such disposition will not require registration of such shares under the

Securities Act. It is agreed that the Company will not require opinions of

counsel for transactions made pursuant to Rule 144 except in unusual

circumstances.

Notwithstanding the provisions of paragraphs (i) and (ii) above,

no such registration statement, detailed statement or opinion of counsel shall

be necessary for a transfer by a party hereto which is (A) a partnership to its

partners or former partners in accordance with partnership interests, (B) a

corporation to its shareholders in accordance with their interest in the

corporation, (C) a limited liability company to its members or former members in

accordance with their interest in the limited liability company, (D) to the

party's family member or trust for the benefit of an individual party, (E) an

entity which is controlled by, controls or is under common control with the

transferor (an "Affiliate"), or (F) a Common Stock Investor to another Common

Stock Investor or then current employees of the Company; provided that in each

case the transferee will be subject to the terms of this Agreement to the same

extent as if he, she or it were an original party hereunder.

(B) Each certificate representing Shares or Registrable

Securities shall (unless otherwise permitted by the provisions of the Agreement)

be stamped or otherwise imprinted with a legend substantially similar to the

following (in addition to any legend required under applicable state securities

laws or under any other agreement):

THE SHARES REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED UNDER

THE SECURITIES ACT OF 1933, AS AMENDED, OR THE STATE SECURITIES OR BLUE SKY

LAWS OF ANY JURISDICTION. SUCH SHARES MAY NOT BE SOLD, OFFERED FOR SALE,

PLEDGED OR TRANSFERRED IN THE ABSENCE OF AN EFFECTIVE REGISTRATION

STATEMENT AS TO THE SECURITIES UNDER SAID ACT AND SECURITIES LAWS OR AN

OPINION OF COUNSEL SATISFACTORY TO THE CORPORATION THAT SUCH REGISTRATION

IS NOT REQUIRED. COPIES OF THE AGREEMENTS COVERING THE PURCHASE OF THESE

SHARES AND RESTRICTING THEIR TRANSFER MAY BE OBTAINED AT NO COST BY WRITTEN

REQUEST MADE BY THE HOLDER OF RECORD

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OF THIS CERTIFICATE TO THE SECRETARY OF THE CORPORATION AT THE PRINCIPAL

EXECUTIVE OFFICES OF THE CORPORATION.

(C) If such Shares or Registrable Securities are proposed to be

disposed of, the Company shall be obligated to reissue promptly certificates

without the foregoing legend at the request of any holder thereof if the holder

shall have obtained an opinion of counsel (which counsel may be counsel to the

Company) reasonably acceptable to the Company to the effect that the securities

may lawfully be so disposed of thereafter without registration, qualification,

or legend.

2.2. DEMAND REGISTRATION.

(A) Subject to the conditions of this Section 2.2, if the Company

shall receive a written request from a Holder or Holders of at least 50% of the

Registrable Securities then outstanding (the "Initiating Holders") that the

Company file a registration statement under the Securities Act covering the

registration of a majority of the Registrable Securities owned by such

Initiating Holders, then the Company shall, within 30 days of receipt thereof,

give written notice of such request to all Holders and, subject to the

limitations of this Section 2.2, use its commercially reasonable efforts to file

a registration statement under the Securities Act with the Commission covering

all Registrable Securities that the Initiating Holders request to be registered.

(B) If the Initiating Holders intend to distribute the

Registrable Securities covered by their request by means of an underwriting,

they shall so advise the Company as a part of their request made pursuant to

this Section 2.2 and the Company shall include such information in the written

notice referred to in Section 2.2(a), as applicable. In such event, the right of

any Holder to include its Registrable Securities in such registration shall be

conditioned upon such Holder's participation in such underwriting and the

inclusion of such Holder's Registrable Securities in the underwriting to the

extent provided herein. All Holders proposing to distribute their securities

through such underwriting shall enter into an underwriting agreement in

customary form with the underwriter or underwriters selected for such

underwriting by the Company (which underwriter or underwriters shall be

reasonably acceptable to a majority in interest of the Initiating Holders).

Notwithstanding any other provision of this Section 2.2, if the underwriter

advises the Company that marketing factors require a limitation of the number of

securities to be underwritten (including Registrable Securities) then the

Company shall so advise all Holders of Registrable Securities that would

otherwise be underwritten pursuant hereto, and the number of shares that may be

included in the underwriting shall be allocated first to the Holders who are

holders of Series C Convertible Preferred Stock (or shares of Common Stock

issued upon conversion thereof), Series B Convertible Preferred Stock (or shares

of Common Stock issued upon conversion thereof) and Series A Convertible

Preferred Stock (or shares of Common Stock issued upon conversion thereof) on a

pro rata basis based on the total number of Registrable Securities held by such

Holders of Series C Convertible Preferred Stock, Series B Convertible Preferred

Stock and Series A Convertible Preferred Stock; provided, however, that the

number of shares of Registrable Securities to be included in such underwriting

and registration shall not be reduced unless all other securities of the Company

are first entirely excluded from the underwriting and registration, and in any

event, by not more than fifty-percent (50%) of the number of shares of

Registrable Securities requested to be so included. Any

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Registrable Securities excluded or withdrawn from such underwriting shall be

withdrawn from the registration.

(C) The Company shall not be required to effect a registration

pursuant to this Section 2.2:

(1) prior to the earlier of (A) six months following a

Qualified Offering, and (B) December 31, 2005;

(2) after the Company has effected two (2) registrations

pursuant to Section 2.2(a), and such registrations have been declared or ordered

effective;

(3) during the period starting with the date of filing of,

and ending on the date 90 days following the effective date of, any registration

statement (other than a Special Registration Statement) of the Company;

(4) if within 30 days of receipt of a written request from

Initiating Holders pursuant to Section 2.2(a), the Company gives notice to the

Holders of the Company's intention to make a Qualified Offering within 90 days;

(5) if the Company shall furnish to the Initiating Holders,

a certificate signed by the Chairman of the Board of Directors stating that in

the good faith judgment of the Board of Directors, it would be seriously

detrimental to the Company and its stockholders for such registration statement

to be effected at such time, in which event the Company shall have the right to

defer such filing for a period of not more than 120 days after receipt of the

request of the Initiating Holders; provided that such right to delay a request

shall be exercised by the Company not more than once in any twelve-month period;

or

(6) if the Initiating Holders propose to dispose of shares

of Registrable Securities that may be immediately registered on Form S-3

pursuant to a request made pursuant to Section 2.4 below.

2.3. PIGGYBACK REGISTRATIONS. The Company shall notify all Holders of

Registrable Securities in writing at least 20 days prior to the filing of any

registration statement under the Securities Act for purposes of a public

offering of securities of the Company (including, but not limited to,

registration statements relating to secondary offerings of securities of the

Company, but excluding Special Registration Statements) and will afford each

such Holder an opportunity to include in such registration statement all or part

of such Registrable Securities held by such Holder. Each Holder desiring to

include in any such registration statement all or any part of the Registrable

Securities held by it shall, within 15 days after the above-described notice

from the Company, so notify the Company in writing. Such notice shall state the

intended method of disposition of the Registrable Securities by such Holder. If

a Holder decides not to include all of its Registrable Securities in any

registration statement thereafter filed by the Company, such Holder shall

nevertheless continue to have the right to include any Registrable Securities in

any subsequent registration statement or registration statements as may be filed

by the Company with respect to offerings of its securities, all upon the terms

and conditions set forth herein.

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(A) UNDERWRITING. If the registration statement under which the

Company gives notice under this Section 2.3 is for an underwritten offering, the

Company shall so advise the Holders of Registrable Securities. In such event,

the right of any such Holder to be included in a registration pursuant to this

Section 2.3 shall be conditioned upon such Holder's participation in such

underwriting and the inclusion of such Holder's Registrable Securities in the

underwriting to the extent provided herein. All Holders proposing to distribute

their Registrable Securities through such underwriting shall enter into an

underwriting agreement in customary form with the underwriter or underwriters

selected for such underwriting by the Company. Notwithstanding any other

provision of the Agreement, if the underwriter determines in good faith that

marketing factors require a limitation of the number of shares to be

underwritten, the number of shares that may be included in the underwriting

shall be allocated, first, to the Company; second, to the Holders who are

holders of Series C Convertible Preferred Stock (or shares of Common Stock

issued upon conversion thereof), Series B Convertible Preferred Stock (or shares

of Common Stock issued upon conversion thereof) and Series A Convertible

Preferred Stock (or shares of Common Stock issued upon conversion thereof) on a

pro rata basis based on the total number of Registrable Securities held by such

Holders of Series C Convertible Preferred Stock, Series B Convertible Preferred

Stock and Series A Convertible Preferred Stock; and third, to the Holders who

are holders of Common Stock (issued otherwise than upon conversion of Series C

Convertible Preferred Stock, Series B Convertible Preferred Stock or Series A

Convertible Preferred Stock) on a pro rata basis based on the total number of

Registrable Securities held by such Holders; provided, however, that the number

of shares of Registrable Securities to be included in such underwriting and

registration shall not be reduced unless all other securities of the Company

(other than securities being offered by the Company and Registrable Securities

being offered by the Holders) are first entirely excluded from the underwriting

and registration. If any Holder disapproves of the terms of any such

underwriting, such Holder may elect to withdraw therefrom by written notice to

the Company and the underwriter, delivered at least ten business days prior to

the effective date of the registration statement. Any Registrable Securities

excluded or withdrawn from such underwriting shall be excluded and withdrawn

from the registration. For any Holder that is a partnership or corporation, the

partners, retired partners, stockholders and Affiliates of such Holder, or the

estates and family members of any such partners and retired partners and any

trusts for the benefit of any of the foregoing person shall be deemed to be a

single "Holder," and any pro rata reduction with respect to such "Holder" shall

be based upon the aggregate amount of shares of Registrable Securities owned by

all entities and individuals included in such "Holder," as defined in this

sentence.

(B) RIGHT TO TERMINATE REGISTRATION. The Company shall have the

right to terminate or withdraw any registration initiated by it under this

Section 2.3 prior to the effectiveness of such registration whether or not any

Holder has elected to include securities in such registration. The Registration

Expenses of such withdrawn registration shall be borne by the Company in

accordance with Section 2.5 hereof.

2.4. FORM S-2 AND S-3 REGISTRATION. In case the Company shall receive

from a Holder or Holders of at least 50% of the Registrable Securities then

outstanding a written request or requests that the Company effect a registration

on Form S-2 or Form S-3 or any similar short-form registration statement and any

related qualification or compliance with respect to all or a part of the

Registrable Securities owned by such Holder or Holders, the Company will:

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(A) promptly give written notice of the proposed registration,

and any related qualification or compliance, to all other Holders of Registrable

Securities; and

(B) as soon as practicable, use its best efforts to file such

registration statement as may be so requested and as would permit or facilitate

the sale and distribution of all or such portion of such Holder's Registrable

Securities as are specified in such request, together with all or such portion

of the Registrable Securities of any other Holder or Holders joining in such

request as are specified in a written request given within 15 days after receipt

of such written notice from the Company; provided, however, that the Company

shall not be obligated to effect any such registration, qualification or

compliance pursuant to this Section 2.4:

(I) if Form S-2 or Form S-3, as the case may be, is not

available for such offering by the Holders, or

(II) if the Company shall furnish to the Holders a

certificate signed by the Chairman of the Board of Directors stating that in the

good faith judgment of the Board of Directors, it would be seriously detrimental

to the Company and its stockholders for such Form S-2 or Form S-3 registration

to be effected at such time, in which event the Company shall have the right to

defer the filing of the registration statement for a period of not more than 90

days after receipt of the request of the Holder or Holders under this Section

2.4; provided, that such right to delay a request shall be exercised by the

Company not more than once in any twelve-month period, or

(III) in any particular jurisdiction in which the Company

would be required to qualify to do business or to execute a general consent to

service of process in effecting such registration, qualification or compliance,

or

(IV) if the Holders, together with the holders of any other

securities of the Company entitled to inclusion in such Form S-2 or Form S-3

registration statement, propose to sell Registrable Securities and such other

securities (if any) at an aggregate price to the public of less than $3,000,000;

or

(V) if the Company has filed a registration statement at the

request of Holders under this Section 2.4 within the preceding six months.

(C) Subject to the foregoing, the Company shall file a Form S-2

or Form S-3 registration statement, as the case may be, covering the Registrable

Securities and other securities so requested to be registered as soon as

practicable after receipt of the request or requests of the Holders.

Registrations effected pursuant to this Section 2.4 shall not be counted as

demands for registration or registrations effected pursuant to Sections 2.2 or

2.3, respectively.

(D) If the registration statement under which the Company gives

notice under this Section 2.4 is for an underwritten offering, the Company shall

so advise the Holders of Registrable Securities. In such event, the right of any

such Holder to be included in a registration pursuant to this Section 2.4 shall

be conditioned upon such Holder's participation in such underwriting and the

inclusion of such Holder's Registrable Securities in the underwriting to the

extent provided herein. All Holders proposing to distribute their Registrable

Securities through such underwriting shall enter into an underwriting agreement

in customary form with the

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underwriter or underwriters selected for such underwriting by the Company.

Notwithstanding any other provision of this Agreement, if the underwriter

determines in good faith that marketing factors require a limitation of the

number of shares to be underwritten, the number of shares that may be included

in the underwriting shall be allocated, first, to the Holders who are holders of

Series C Convertible Preferred Stock (or shares of Common Stock issued upon

conversion thereof), Series B Convertible Preferred Stock (or shares of Common

Stock issued upon conversion thereof) and Series A Convertible Preferred Stock

(or shares of Common Stock issued upon conversion thereof) on a pro rata basis

based on the total number of Registrable Securities held by such Holders of

Series C Convertible Preferred Stock, Series B Convertible Preferred Stock and

Series A Convertible Preferred Stock; and second, to the Holders who are holders

of Common Stock (issued other than upon conversion of the Series C Convertible

Preferred Stock, Series B Convertible Preferred Stock or Series A Convertible

Preferred Stock) on a pro rata basis based on the total number of Registrable

Securities held by such Holders; provided, however, that the number of shares of

Registrable Securities to be included in such underwriting and registration

shall not be reduced unless all other securities of the Company (other than

securities being offered by the Company and Registrable Securities being offered

by the Holders) are first entirely excluded from the underwriting and

registration. If any Holder disapproves of the terms of any such underwriting,

such Holder may elect to withdraw therefrom by written notice to the Company and

the underwriter, delivered at least ten (10) business days prior to the

effective date of the registration statement. Any Registrable Securities

excluded or withdrawn from such underwriting shall be excluded and withdrawn

from the registration. For any Holder which is a partnership or corporation, the

partners, retired partners, stockholders and Affiliates of such Holder, or the

estates and family members of any such partners and retired partners and any

trusts for the benefit of any of the foregoing person shall be deemed to be a

single "Holder," and any pro rata reduction with respect to such "Holder" shall

be based upon the aggregate amount of shares of Registrable Securities owned by

all entities and individuals included in such "Holder," as defined in this

sentence.

2.5. EXPENSES OF REGISTRATION. Except as specifically provided

herein, all Registration Expenses incurred in connection with any registration,

qualification or compliance pursuant to Section 2.2 or any registration under

Section 2.3 or Section 2.4 herein shall be borne by the Company; provided,

however, that the Company shall not be required to pay any Registration Expenses

incurred in connection with any registration, qualification or compliance

proceedings begun pursuant to a request under Section 2.2 if such request is

subsequently withdrawn by the Holders of a majority of the Registrable

Securities to be included in such registration, qualification or compliance (in

which case all participating Holders shall bear all such Registration Expenses).

All Selling Expenses incurred in connection with any registrations hereunder,

shall be borne by the holders of the securities so registered pro rata on the

basis of the number of shares so registered and sold.

2.6. OBLIGATIONS OF THE COMPANY. Whenever required to effect the

registration of any Registrable Securities, the Company shall, as expeditiously

as reasonably possible:

(A) Prepare and file with the SEC a registration statement with

respect to such Registrable Securities and use all reasonable efforts to cause

such registration statement to become effective, and, upon the request of the

Holders of a majority of the Registrable Securities

<PAGE>

registered thereunder, keep such registration statement effective (i) in the

case of any registration under Section 2.2, for up to 180 days or, if earlier,

until the Holder or Holders have completed the distribution related thereto and

(ii) in the case of any registration under Section 2.4, indefinitely or, if

earlier, until the Holder or Holders have completed the distribution related

thereto.

(B) Prepare and file with the SEC such amendments and supplements

to such registration statement and the prospectus used in connection with such

registration statement as may be necessary to comply with the provisions of the

S


 
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