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EX-10.4 LEASE BY AND BETWEEN TRUSTEES OF 4 MAGUIRE

Industrial Lease Agreement

EX-10.4 LEASE BY AND BETWEEN TRUSTEES OF 4 MAGUIRE | Document Parties: TRUSTEES OF 4 MAGUIRE ROAD REALTY TRUST | PREDIX PHARMACEUTICALS HOLDINGS, INC You are currently viewing:
This Industrial Lease Agreement involves

TRUSTEES OF 4 MAGUIRE ROAD REALTY TRUST | PREDIX PHARMACEUTICALS HOLDINGS, INC

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Title: EX-10.4 LEASE BY AND BETWEEN TRUSTEES OF 4 MAGUIRE
Governing Law: Massachusetts     Date: 8/3/2005

EX-10.4 LEASE BY AND BETWEEN TRUSTEES OF 4 MAGUIRE, Parties: trustees of 4 maguire road realty trust , predix pharmaceuticals holdings  inc
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                                                                    EXHIBIT 10.4

 

                                      LEASE

 

                                 BY AND BETWEEN

 

                     TRUSTEES OF 4 MAGUIRE ROAD REALTY TRUST

                                     LANDLORD

 

                                       AND

 

                      PREDIX PHARMACEUTICALS HOLDINGS, INC.

                                     TENANT

 

                                 4 MAGUIRE ROAD

                             LEXINGTON, MASSACHUSETTS

 

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                                Table of Contents

 

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ARTICLE 1   Reference Data..............................................     1

 

   1.1    Introduction and Subjects Referred To.........................     1

   1.2    Exhibits......................................................     2

 

ARTICLE 2   Premises and Term...........................................     3

 

   2.1    Premises......................................................     3

   2.2    Term..........................................................     3

   2.3    Extension Option..............................................     3

   2.4    Measurement of the Premises and Building......................     5

 

ARTICLE 3   Commencement and Condition..................................     5

 

   3.1    Commencement Date.............................................     5

   3.2    Preparation of the Premises...................................     5

   3.3    Conclusiveness of Landlord's Performance......................     7

   3.4    Tenant Delay: Force Majeure...................................     7

   3.5    Construction Representatives..................................     9

   3.6    Application of Remaining Contribution.........................     9

   3.7    Early Access..................................................    10

 

ARTICLE 4   Rent, Additional Rent, Insurance and Other Charges..........    10

 

   4.1    The Annual Fixed Rent.........................................    10

   4.2    Additional Rent...............................................    10

         4.2.1 Real Estate Taxes.......................................    11

         4.2.2 Operating Costs.........................................    12

   4.3    Personal Property and Sales Taxes.............................    16

   4.4    Insurance.....................................................    16

   4.5    Utilities.....................................................    17

   4.6    Late Payment of Rent..........................................    18

   4.7    Security Deposit..............................................    18

 

ARTICLE 5   Landlord's Covenants........................................    20

 

   5.1    Affirmative Covenants.........................................    20

         5.1.1 Heat and Air-Conditioning...............................    20

         5.1.2 Landscaping.............................................    20

         5.1.3 Elevator, Lighting and Electricity......................    20

         5.1.4 Repairs.................................................    21

   5.2    Interruption..................................................    21

   5.3    Outside Services..............................................    21

   5.4    Access to Building............................................    21

   5.5    Parking.......................................................    22

   5.6    Compliance with Americans with Disabilities Act...............    22

   5.7    Hazardous Waste Representation and Covenants..................    22

   5.8    Indemnification...............................................    23

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ARTICLE 6   Tenant's Additional Covenants..................................................    23

 

   6.1    Affirmative Covenants............................................................    23

         6.1.1 Perform Obligations........................................................    23

         6.1.2 Use........................................................................    23

         6.1.3 Repair and Maintenance.....................................................    23

         6.1.4 Compliance with Law........................................................    24

         6.1.5 Indemnification............................................................    24

         6.1.6 Landlord's Right to Enter..................................................    25

         6.1.7 Personal Property at Tenant's Risk.........................................    25

         6.1.8 Payment of Landlord's Cost of Enforcement..................................    25

         6.1.9 Yield Up...................................................................    26

         6.1.10 Rules and Regulations.....................................................    27

         6.1.11 Estoppel Certificate......................................................    27

         6.1.12 Landlord's Expenses For Consents..........................................    27

         6.1.13 Financial Information.....................................................    27

   6.2    Negative Covenants...............................................................    27

         6.2.1 Assignment and Subletting..................................................    27

         6.2.2 Nuisance...................................................................    31

         6.2.3 Floor Load; Heavy Equipment................................................    31

         6.2.4 Electricity................................................................    32

         6.2.5 Installation, Alterations or Additions.....................................    32

         6.2.6 Intentionally Deleted......................................................    33

         6.2.7 Signs......................................................................    33

         6.2.8 Oil and Hazardous Materials................................................    34

 

ARTICLE 7   Casualty or Taking.............................................................    35

 

   7.1    Termination......................................................................    35

         7.1.1 Termination by Landlord ...................................................    35

         7.1.2 Termination by Tenant......................................................    36

   7.2    Restoration......................................................................    36

   7.3    Award............................................................................    37

   7.4    Effect of Casualty or Taking on the Tax Excess and the Operating Cost Excess.....    37

 

ARTICLE 8   Defaults.......................................................................    37

 

   8.1    Default of Tenant................................................................    37

   8.2    Remedies.........................................................................    38

   8.3    Remedies Cumulative..............................................................    40

   8.4    Landlord's Right to Cure Defaults................................................    40

   8.5    Holding Over.....................................................................    41

   8.6    Effect of Waivers of Default.....................................................    41

   8.7    No Waiver, etc...................................................................    41

   8.8    No Accord and Satisfaction.......................................................    41

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ARTICLE 9   Rights of Holders..............................................................    42

 

   9.1    Rights of Mortgagees or Ground Lessor............................................    42

   9.2    Modifications....................................................................    43

   9.3    Subordination, Non-Disturbance and Attornment....................................    43

 

ARTICLE 10   Miscellaneous Provisions......................................................    43

 

   10.1   Notices..........................................................................    43

   10.2   Quiet Enjoyment; Landlord's Right to Make Alterations, Etc.......................    43

   10.3   Recording of Lease; Confidentiality of Lease Terms...............................    44

   10.4   Assignment of Rents and Transfer of Title; Limitation of Landlord's Liability....    44

   10.5   Landlord's Default...............................................................    45

   10.6   Notice to Mortgagee and Ground Lessor............................................    46

   10.7   Brokerage........................................................................    46

   10.8   Applicable Law and Construction..................................................    46

 

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                                      iii

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                                       LEASE

 

                                 4 Maguire Road

                            Lexington, Massachusetts

 

                                   ARTICLE 1

 

                                 Reference Data

 

1.1 Introduction and Subjects Referred To.

 

      This is a lease (this "Lease") entered into by and between Trustees of 4

Maguire Road Realty Trust, under Declaration of Trust dated January 30, 1998 and

filed with Middlesex County Registry District of the Land Court as Document No.

1054066 ("Landlord") and Predix Pharmaceuticals Holdings, Inc., a Delaware

corporation ("Tenant").

 

      Each reference in this Lease to any of the following terms or phrases

shall be construed to incorporate the corresponding definition stated in this

Section 1.1.

 

       Date of this Lease:        January 25, 2005.

 

      Building and Property:     That building in the Town of Lexington,

                                Massachusetts known as 4 Maguire Road (the

                                "Building"). The Building and the land parcels

                                on which it is located and the sidewalks

                                adjacent thereto are hereinafter collectively

                                referred to as the "Property".

 

      Premises:                   A portion of the first floor of the Building

                                containing a pH neutralization tank and related

                                equipment, the exact location and size to be

                                determined by Landlord and Tenant by the Final

                                Plans Date, and the entire rentable area on the

                                second floor of the Building, substantially as

                                shown on Exhibit A hereto.

 

       Premises Rentable Area:    27,500 square feet, subject to the provisions of

                                Section 2.4.

 

      Original Term:             Seven (7) years and two (2) months, commencing

                                on the Commencement Date and expiring on the day

                                preceding the seventh anniversary of the Rent

                                Commencement Date.

 

      Annual Fixed Rent:         The sum of (i) for the period commencing on the

                                 Rent Commencement Date and expiring on the day

                                preceding the first anniversary of the Rent

                                Commencement Date, $16.29 per square foot of

                                Premises Rentable Area, (ii) for the period

                                commencing on the first anniversary of the Rent

                                Commencement Date and expiring on the day

                                preceding the second anniversary of the Rent

                                Commencement Date, $19.55

 

                                      -1-

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                                per square foot of Premises Rentable Area, (iii)

                                for the period commencing on the second

                                anniversary of the Rent Commencement Date and

                                expiring on the day preceding the fifth

                                anniversary of the Rent Commencement Date,

                                 $25.00 per square foot of Premises Rentable Area

                                per annum, and (iv) for the remaining two (2)

                                years of the Original Term, $27.50 per square

                                foot of Premises Rentable Area per annum. The

                                first Year shall be the period commencing on the

                                Rent Commencement Date and expiring on the day

                                preceding the first anniversary of the Rent

                                Commencement Date, and each subsequent

                                twelve-month period shall be a subsequent Year.

 

      Tenant's Percentage:       Fifty percent (50%), subject to the provisions

                                 of Section 2.4.

 

      Permitted Uses:            General offices and pharmaceutical research and

                                laboratory purposes and any other lawful

                                purposes ancillary to the aforesaid principle

                                uses, subject to the provisions of Subsection

                                6.1.2.

 

      Plan Submission Date:      March 2, 2005.

 

      Final Plans Date:          March 31, 2005.

 

      Security Deposit:          $450,000, subject to reduction as provided in

                                Section 4.7.

 

      Commercial General         $5,000,000 per occurrence (combined single

      Liability Insurance        limit) for property damage, bodily and personal

      Limits:                    injury and death.

 

      Original Address of        c/o Reit Management & Research LLC

      Landlord:                  400 Centre Street

                                Newton, Massachusetts 02458

 

      Original Address of        10K Gill Street

      Tenant:                    Woburn, Massachusetts 01801

 

      1.2    Exhibits.

 

      The Exhibits listed below in this section are incorporated in this Lease

by reference and are to be construed as a part of this Lease.

 

       EXHIBIT A. Plan showing the Premises.

      EXHIBIT A-1. Plan Showing Location of Tenant's Visitor Parking Spaces

      EXHIBIT B. Rules and Regulations.

      EXHIBIT C. Alterations Requirements.

      EXHIBIT D. Contractor's Insurance Requirements.

       EXHIBIT E. Clerk's Certificate.

      EXHIBIT 1. Shell and Core Work.

      EXHIBIT 2. Exterior Work.

 

                                      -2-

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                                   ARTICLE 2

 

                                Premises and Term

 

       2.1 Premises. Landlord hereby leases to Tenant and Tenant hereby leases

from Landlord, subject to and with the benefit of the terms, covenants,

conditions and provisions of this Lease, the Premises, excluding exterior faces

of exterior walls, the common lobbies, hallways, stairways, stairwells, elevator

shafts and other common areas, and the escalators, elevators, pipes, ducts,

conduits, wires and appurtenant fixtures and other common facilities serving the

common areas, the Premises and the premises of other tenants in the Building.

 

      Tenant shall have, as appurtenant to the Premises, rights to use, in

common with others, subject to reasonable rules of general applicability to

tenants of the Building from time to time made by Landlord of which Tenant is

given notice: (a) the common lobbies, hallways and stairways and loading docks

of the Building, (b) the common escalators, elevators, pipes, ducts, conduits,

wires and appurtenant fixtures and other common facilities serving the Premises,

and (c) common walkways and driveways (if any) necessary for access to the

Building.

 

      2.2 Term. The term of this Lease shall be for a period beginning on the

Commencement Date (as defined in Section 3.1) and continuing for the Original

Term and any extension of the term hereof in accordance with the provision of

this Lease, unless sooner terminated as hereinafter provided. When the dates of

the beginning and end of the Original Term have been determined such dates shall

be evidenced by a document executed by Landlord and Tenant and delivered each to

the other, but the failure of Landlord and Tenant to execute or deliver such

document shall have no effect upon such dates. The Original Term and any

extension of the term hereof in accordance with the provisions of this Lease is

hereinafter referred to as the "term" of this Lease.

 

      2.3 Extension Option. So long as this Lease is still in full force and

effect, and the named Tenant as set forth in Section 1.1(or any successor by

merger, or any Affiliate) shall actually occupy at least seventy percent (70%)

of the Premises, Tenant shall have the right to extend the term of this Lease

for two (2) additional periods (the "Extended Term(s)") of three (3) years each.

Each Extended Term shall commence on the day succeeding the expiration of the

Original Term or the preceding Extended Term, as the case may be, and shall end

on the day immediately preceding the third anniversary of the commencement of

such Extended Term. All of the terms, covenants and provisions of this Lease

applicable immediately prior to the expiration of the then current term (i.e.

Original Term or Extended Term, as applicable) shall apply to each such Extended

Term except that (i) the Annual Fixed Rent for each such Extended Term shall be

ninety-five percent (95%) of the Market Rate (as hereinafter defined) for the

Premises determined as of the commencement of such Extended Term, as designated

by Landlord by notice to Tenant ("Landlord's Notice"), but subject to Tenant's

right to dispute as hereinafter provided; and (ii) Tenant shall have no further

right to extend the term of this Lease beyond the Extended Terms hereinabove

provided. If Tenant shall elect to exercise any of the aforesaid options, it

shall do so by giving Landlord notice ("Tenant's Extension Notice") of its

election not later than one year, nor sooner than eighteen (18) months, prior to

the expiration of the then current term of this Lease (Original Term or Extended

Term, as applicable). If Tenant fails to give any such notice to Landlord, the

term of this Lease shall automatically terminate no

 

                                      -3-

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later than the end of the term then in effect, and Tenant shall have no further

option to extend the term of this Lease, it being agreed that time is of the

essence with respect to the giving of any such notice. If Tenant shall extend

the term hereof pursuant to the provisions of this Section 2.3, such extension

shall be automatically effected without the execution of any additional

documents, but Tenant shall, at Landlord's request, execute an agreement

confirming the Annual Fixed Rent for the applicable Extended Term.

 

      "Market Rate" shall mean the then fair market annual rental rate and terms

for the Premises for the applicable period (determined as set forth below).

Within thirty (30) days after Landlord's receipt of a Tenant's Extension Notice,

Landlord shall provide Landlord's Notice. Within thirty (30) days after Tenant's

receipt of Landlord's Notice, Tenant shall either accept Landlord's

determination of the Market Rate or shall propose its determination of the

Market Rate by providing notice to Landlord. If Tenant disagrees with Landlord's

designation of the Market Rate, the parties shall meet for the purpose of

reaching agreement. If the parties cannot agree upon the Market Rate by the date

that is thirty (30) days following Landlord's receipt of Tenant's proposal, then

the Market Rate shall be submitted to appraisal as follows: Within fifteen (15)

days after the expiration of such thirty (30) day period, Landlord and Tenant

shall designate a mutually acceptable appraiser, or either party then may

request the American Arbitration Association, Boston office (or any successor

organization) to designate an independent appraiser in accordance with its then

prevailing rules.

 

      Any appraisers selected as herein provided shall have at least ten (10)

years experience in the leasing, ownership or management of 1,000,000 or more

square feet of floor area of properties of the same type and quality as the

Building in the Route 128 market area. Each party shall pay one half (1/2) of

the fees and expenses of the appraiser and all other expenses of the appraisal.

The parties shall have the opportunity to present evidence in accordance with

reasonable procedures prescribed by the appraiser. The decision and award of the

appraiser shall be in writing and shall be final and conclusive on all parties,

and counterpart copies thereof shall be delivered to both Landlord and Tenant.

Judgment upon the award of the appraiser may be entered in any court of

competent jurisdiction.

 

      The appraiser shall select the Market Rate determination of either

Landlord or Tenant that the appraiser considers closest to his or her own

determination of the Market Rate of the Premises for the applicable Extended

Term and render a decision and award as to such determination to both Landlord

and Tenant (a) within twenty (20) days after the appointment of the appraiser.

In rendering such decision and award, the appraiser shall assume (i) that the

Premises are available in the then rental market, (ii) that Landlord has had a

reasonable time to locate a tenant, (iii) that neither Landlord nor the

prospective tenant is under a compulsion to rent, (iv) that Landlord and Tenant

are typically motivated, well-informed and well-advised, and each is acting in

what it considers its own best interest, (v) the Premises are appropriate and

desired for immediate occupancy by Tenant and contain no work that has been

carried out thereon by Tenant, its subtenant(s), or its or their

successors-in-interest during the Term of this Lease which has diminished the

rental value of the Premises, and (vi) that in the event the Premises are

destroyed or damaged by fire or other casualty prior to the commencement of the

applicable Extended Term, they have been fully restored. In rendering such

decision and award, the appraiser shall consider the fair market annual rents

(as the same may change over time and considering any rent abatement or other

offset against stated annual rents) then being charged for

 

                                      -4-

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comparable space in comparable buildings for the period of the applicable

Extended Term in the Route 128 market area, but shall not modify the provisions

of this Lease.

 

      If the dispute between the parties as to the Market Rate has not been

resolved before the commencement of Tenant's obligation to pay the Annual Fixed

Rent based upon determination of such Market Rate, then Tenant shall pay the

Annual Fixed Rent under the Lease for the annual period just ended until either

the agreement of the parties as to the Market Rate, or the decision of the

appraiser(s), as the case may be, at which time Tenant shall pay any

underpayment of the Annual Fixed Rent to Landlord, or Landlord shall refund any

overpayment of the Annual Fixed Rent to Tenant.

 

      2.4 Measurement of the Premises and Building. Landlord shall cause its

architect to determine the measurement of the Premises and the Building in

accordance with the ANSI/BOMA Z65.1 1996 standards. Such measurement shall occur

only once, shall be made only after reasonable prior notice to Tenant, and at

Tenant's request the architect shall meet with Tenant or its architect to

provide any appropriate substantiation.

 

       If the rentable area of the Premises, as so measured, is different from

the Premises Rentable Area as set forth in Section 1. 1, the definition of

Premises Rentable Area for all purposes (e.g. Annual Fixed Rent, Landlord's

Contribution and the Applied Rent Amount) shall be deemed amended in accordance

with such measurement, and if the Premises Rentable Area as so measured is not

one-half of the rentable area of the Building as so measured ("Building Rentable

Area"), Tenant's Percentage shall be amended to be the ratio of the Premises

Rentable Areas as so measured to Building Rentable Area, all retroactively to

the Commencement Date.

 

      In the event of any adjustment pursuant to this Section 2.3, Landlord and

Tenant shall promptly execute a written statement setting forth the recomputed

Premises Rentable Area and Tenant's Percentage, but the failure by either party

to execute such a statement shall have no effect on the validity of such

recomputation.

 

                                    ARTICLE 3

 

                            Commencement and Condition

 

      3.1 Commencement Date. The Commencement Date shall be the Substantial

Completion Date, as defined in Section 3.2(c).

 

      3.2 Preparation of the Premises.

 

            (a) Landlord and Tenant shall adhere to any schedules for submittals

and decisions reasonably established by The Richmond Group to have final

construction drawings ("Tenant's Plans") for the initial improvements to the

Premises completed on or before the Final Plans Date.

 

            (b) Landlord shall fill in the atrium on the second floor and

perform the alterations and improvements described on Exhibit 1 (the "Shell and

Core Work") and shall perform the alterations and improvements to the exterior

of the Building described on Exhibit 2 (the "Exterior Work"). Landlord shall

cause the improvements to the second floor lobby common

 

                                      -5-

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area to be consistent with adjacent areas of the Premises, and shall seek input

from Tenant regarding the Exterior Work prior to Landlord finalizing plans

therefor.

 

      Promptly after approval by Landlord of Tenant's Plans, Landlord shall also

perform the work specified therein (the "Leasehold Improvement Work", and

together with the Shell and Core Work and the Exterior Work, as may be modified

as hereinafter provided, "Landlord's Work"); and Landlord shall use all

reasonable efforts to complete Landlord's Work diligently, but Tenant shall have

no claim against Landlord or right to terminate this Lease due to failure by

Landlord to complete Landlord's Work by any given date, except as provided in

Section 3.4(d). Landlord shall enter into a contract to perform the Leasehold

Improvement Work with The Richmond Group provided that The Richmond Group shall

execute Landlord's standard form of construction contract containing the

contractor's agreement to perform the Leasehold Improvement Work in accordance

with Tenant's Plans and Landlord's reasonable requirements, including, without

limitation, providing customary contractor insurance and performance and payment

bonds and to substantially complete the Leasehold Improvement Work not later

than August 31, 2005 (the "Target Delivery Date"), subject to Force Majeure and

Tenant Delay, as hereinafter defined; otherwise Landlord shall be free to select

the contractor to perform the Leasehold Improvement Work on the foregoing terms.

 

      Landlord shall perform the Shell and Core Work and the Exterior Work at

its sole cost and expense, in a good and workmanlike manner, using materials

that are new, commercial grade and of first-class quality. Tenant agrees that

Landlord may make any changes in Landlord's Work from that shown on Tenant's

Plans or the Exhibits to this Lease, the necessity or desirability of which

becomes apparent following the Date of this Lease, upon prior written notice to

Tenant for changes that are not substantial (either individually or in the

aggregate) and do not increase the cost of Landlord's Work (either individually

or in the aggregate) and with the approval of Tenant (which approval shall not

be unreasonably withheld or delayed) for all other changes. Landlord shall

provide Tenant with an allowance ("Landlord's Contribution") of One hundred

dollars ($100.00) per square foot of Premises Rentable Area for the performance

of the Leasehold Improvement Work. To the extent that the cost of the Leasehold

Improvement Work exceeds Landlord's Contribution (such excess being the "Excess

Cost"), Tenant shall (at Landlord's election) (i) pay fifty percent (50%) of the

Excess Cost (as estimated by Landlord) to Landlord upon approval by Landlord of

Tenant's Plans and the remainder of such Excess Cost within ten (10) days after

delivery to Tenant of a final accounting of the cost of the Leasehold

Improvement Work, or (ii) pay the entire Excess Cost within ten (10) days after

delivery to Tenant of a final accounting of the cost of Leasehold Improvement

Work. For purposes of this subsection (b), "cost" shall be the actual cost to

Landlord of performing the Leasehold Improvement Work including, without

limitation, all architectural and engineering fees and expenses in preparing

Tenant's Plans or otherwise and all filing fees and other permitting costs and

all contractor charges ("Contractor Charges") for the cost of work and

materials, profit, general conditions and overhead and supervision, plus five

percent (5%) of Contractor Charges as a fee for administering the Leasehold

Improvement Work on behalf of Landlord. Tenant shall, if requested by Landlord,

execute an agreement (the "Excess Cost Amendment") confirming Landlord's

estimate of such Excess Cost, and (subject to Landlord's obligation to

substantiate the actual Excess Cost following completion of Landlord's Work)

Tenant's obligation on account thereof within five (5) Business Days after

Landlord's request therefor.

 

                                      -6-

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            (c) The "Substantial Completion Date" shall be the first day as of

which Landlord's Work has been completed except for items of work (and, if

applicable, adjustment of equipment and fixtures) which can be completed after

occupancy has been taken without causing undue interference with Tenant's use of

the Premises (i.e. so-called "punch list" items), and a temporary or permanent

certificate of occupancy has been issued. Landlord shall complete as soon as

conditions permit all "punch list" items and Tenant shall afford Landlord access

to the Premises for such purposes.

 

      3.3 Conclusiveness of Landlord's Performance. Tenant shall be conclusively

deemed to have accepted Landlord's Work unless, within ten (10) months after the

Commencement Date with regard to heat, ventilation and air-conditioning

equipment and related work or within ninety (90) days after the Commencement

Date with regard to other items, Tenant gives Landlord a notice setting forth in

detail those portions of Landlord's Work Tenant does not accept. Upon Tenant's

request, Landlord shall assign to Tenant any warranties provided to Landlord in

connection with Landlord's Work which are assignable without expense to Landlord

provided Tenant shall release Landlord from any liability with respect to the

matter subject to the warranty.

 

      3.4 Tenant Delay; Force Majeure. A "Tenant Delay" shall be any delay in

the occurrence of the Substantial Completion Date as a result of a Direct Delay

(as defined in Section 3.4 (a)), plus any delay in the occurrence of the

Substantial Completion Date as a result of an Additional Delay (as defined in

Section 3.4(b)). Tenant shall pay to Landlord (as Additional Rent), for each day

of Tenant Delay, the amount of Annual Fixed Rent, Additional Rent and other

charges that would have been payable hereunder as if the Rent Commencement Date

occurred, and the obligation to pay the full amount of Annual Fixed Rent,

Additional Rent and other charges (without abatement) had commenced, immediately

prior to such Tenant Delay.

 

            (a) A "Direct Delay" shall be any of the following:

 

                  (i)    any request by Tenant that Landlord delay in the

                         commencement or completion of the Leasehold Improvement

                        Work or any other portions of Landlord's Work for any

                        reason (other than as a result of Landlord's failure to

                        perform its obligations under this Lease);

 

                  (ii)   Tenant's failure to submit Tenant's Plans by the Plan

                        Submission Date, or to obtain Landlord's approval

                        thereof by the Final Plans Date, or to execute the

                        Excess Cost Agreement if requested by Landlord or to pay

                        when due any Excess Cost;

 

                  (iii) any request by Tenant for any change in any of Tenant's

                        Plans after the Final Plans Date;

 

                  (iv)   any requirement of Tenant's Plans identified by Landlord

                        at time of Landlord's approval of Tenant's Plans as a

                        long lead item; or

 

                  (v)     any other act or omission of Tenant or its officers,

                        agents, servants or contractors (including unreasonable

                        delay or withholding of

 

                                      -7-

<PAGE>

 

                         approval to changes desired by Landlord and which

                        require Tenant's approval, as described in Subsection

                        3.2(b)).

 

            (b) An "Additional Delay" shall be (i) any reasonably necessary

change in Landlord's construction schedule resulting from a Direct Delay or (ii)

any "Force Majeure" condition (as defined in subsection (e) hereof) which would

have occurred after the Substantial Completion Date but for a Direct Delay.

 

            (c) If, as a result of a Tenant Delay, the Substantial Completion

Date is delayed in the aggregate for more than ninety (90) days, Landlord may

(but shall not be required to) at any time thereafter terminate this Lease by

giving notice of such termination to Tenant and thereupon this Lease shall

terminate without further liability or obligation on the part of either party,

except that Tenant shall pay to Landlord the cost theretofore incurred by

Landlord in performing Landlord's Work, plus an amount equal to Landlord's

out-of-pocket expenses incurred in connection with this Lease, including,

without limitation, brokerage and legal fees, together with any amount required

to be paid pursuant to this Section 3.4 through the date of termination. If as a

result of Force Majeure the Substantial Completion Date is delayed for more than

six (6) months, Landlord may (but shall not be required to) at any time

thereafter terminate this Lease by giving notice of such termination to Tenant

and thereupon this Lease shall terminate without further liability or obligation

on the part of either party.

 

            (d) Landlord shall comply with all of its obligations and enforce

all of its rights under the contract it shall execute for the performance of

Landlord's Work. If nevertheless the Substantial Completion Date has not

occurred within ninety (90) days after the Target Delivery Date (as it may be

extended pursuant to Section 3.4), Tenant shall have the right to terminate this

Lease by giving notice to Landlord not later than thirty (30) days after the

expiration of such ninety (90) day period; and this Lease shall cease and come

to an end without further liability or obligation on the part of either party

(except, if applicable, for any undischarged obligations of Tenant arising

pursuant to Section 3.7, which obligations shall remain in effect) on the giving

of such notice, it being agreed that time is of the essence with respect to the

giving of such notice. Tenant's termination right shall be Tenant's sole and

exclusive remedy at law or in equity for Landlord's failure to complete

Landlord's Work.

 

            (e) "Force Majeure" shall be defined as any strike or other labor

trouble, fire, flood or other casualty, breakage, accident, repairs, unusually

severe weather, governmental preemption of priorities or other controls in

connection with a national or other public emergency, governmental moratoria, or

inaction of governmental authority (or shortages of fuel, supplies or labor

resulting therefrom), war, civil commotion, labor or transportation

difficulties, inability to obtain supplies, or any other cause, whether similar

or dissimilar, beyond Landlord's reasonable control.

 

            (f) The Target Delivery Date shall be extended by the number of days

of delay due to any Tenant Delay or Force Majeure.

 

                                      -8-

<PAGE>

 

      3.5 Construction Representatives. Both Landlord and Tenant shall appoint

one individual as its "Construction Representative" who is authorized to act on

its behalf in connection with any matters arising pursuant to this Article 3.

The Construction Representative may be changed from time to time by notice

hereunder from the then current Construction Representative to the other party's

Construction Representative or by notice from Landlord or Tenant pursuant to

Section 10.1. The initial Construction Representatives shall be Michael Marx

(Landlord) and Christine H. Wang (Tenant). Notwithstanding Section 10.1, any

notices or other communication under this Article 3 may be made by letter or

other writing sent by U.S. mail, facsimile or email, provided the communication

is made by one party's Construction Representative to the other party's

Construction Representative.

 

      3.6 Application of Remaining Contribution. To the extent the cost of the

Leasehold Improvement Work shall be less than Landlord's Contribution, Tenant

may apply such difference (the "Difference") toward the following (the

"Associated Costs"): (i) architectural services incurred by Tenant in preparing

Tenant's Plans (including any amounts incurred prior to the Date of this Lease),

(ii) construction management services incurred by Tenant in connection with the

Leasehold Improvement Work, (iii) costs incurred by Tenant to install in the

Premises any "work" as defined in Section 6.2.5 of this Lease including lab

benches and fixtures, (iv) costs (including reasonable third party relocation

management fees) incurred by Tenant in moving from 10K Gill Street to the

Premises, (v) costs incurred by Tenant to install telephone, data and electrical

cabling and wiring in the Premises and (vi) up to $100,000 of costs incurred by

Tenant to purchase new office furniture; and to the extent of the remaining

Difference, Landlord shall reimburse Tenant for such expenses within thirty (30)

days of receipt of request therefor together with paid invoices, and provided

that there shall exist no Default of Tenant and such invoices are delivered to

Landlord prior to the first anniversary of the Commencement Date.

 

      To the extent the cost of the Leasehold Improvement Work plus any amounts

paid by Landlord toward the Associated Costs shall be less than Landlord's

Contribution, up to the Applied Rent Amount of such remaining difference may be

applied to the first installment(s) of Annual Fixed Rent due hereunder, provided

Tenant shall elect to make such application by notice to Landlord on or before

the Rent Commencement Date. The "Applied Rent Amount" is $5.00 per square foot

of Premises Rentable Area.

 

      Should there remain any portion of Landlord's Contribution that shall not

have been applied toward the cost of the Leasehold Improvement Work, the

Associated Costs or application against Annual Fixed Rent as provided in the

previous paragraph, such remaining portion shall be available to reimburse

Tenant for any "work" as defined in Section 6.2.5 of this Lease performed to the

Premises in compliance with the terms of this Lease, further provided that there

shall exist no Default of Tenant and provided paid invoices for such work are

provided to Landlord on or before the fourth anniversary of the Commencement

Date.

 

      Any portion of Landlord's Contribution not applied toward the cost of the

Leasehold Improvement Work, the Associated Costs, credit against Annual Fixed

Rent or work, as described in the three preceding paragraphs, shall be forfeited

by Tenant and shall become Landlord's property.

 

                                      -9-

<PAGE>

 

      3.7 Early Access. Landlord acknowledges that Tenant desires to occupy a

portion of the Premises of approximately five thousand (5,000) rentable square

feet as soon as possible after May 31, 2005, irrespective of the fact that the

Commencement Date may not have occurred. Landlord therefore agrees that, at such

point as, in Landlord's reasonable judgment, Landlord's Work has proceeded to

such point where Tenant may, in compliance with applicable law and building

codes, occupy such portion as desired by Tenant without interfering with the

performance of Landlord's Work, Tenant may occupy such portion of the Premises

for the Permitted Uses. In connection with such access, Tenant agrees to cease

promptly upon notice from Landlord any activity (including mere possession of

such area) which shall interfere with or delay the performance of Landlord's

Work. Such access by Tenant shall be deemed to be subject to all of the

applicable provisions of this Lease, except that the Commencement Date shall not

be deemed to have occurred but Tenant shall pay rent monthly in advance during

such pre-Commencement Date period at a per annum rate of $16.25 per rentable

square foot so occupied. If Tenant fails or refuses to comply with any of the

obligations described or referred to above, then immediately upon notice to

Tenant, Landlord may revoke Tenant's rights of access to the Premises until the

Commencement Date.

 

                                   ARTICLE 4

 

               Rent, Additional Rent, Insurance and Other Charges

 

      4.1 The Annual Fixed Rent. Commencing on that date (the "Rent Commencement

Date") which is two (2) months following the Commencement Date, Tenant shall pay

Annual Fixed Rent to Landlord, or as otherwise directed by Landlord, without

offset, abatement (except as provided in Article 7), deduction or demand. Annual

Fixed Rent shall be payable in equal monthly installments, in advance, on the

first day of each and every calendar month after the Rent Commencement Date and

during the term of this Lease, at the Original Address of Landlord, or at such

other place as Landlord shall from time to time designate by notice, by check

drawn on a domestic bank.

 

      Annual Fixed Rent for any partial month shall be prorated on a daily

basis, and if Annual Fixed Rent commences on a day other than the first day of a

calendar month, the first payment which Tenant shall make to Landlord shall be

payable on the date Annual Fixed Rent commences and shall be equal to such

pro-rated amount plus the installment of Annual Fixed Rent for the succeeding

calendar month. Annual Fixed Rent for any month during which Annual Fixed Rent

shall increase after the first day of such month shall be the sum of similarly

pro-rated amounts for both the period prior to such change and the period from

and after such change.

 

      4.2 Additional Rent. Tenant covenants and agrees to pay Tenant's

Percentage of Taxes and Operating Costs as provided in Sections 4.2.1 and 4.2.2,

and all other charges and amounts payable by or due from Tenant to Landlord (all

such amounts referred to in this sentence being "Additional Rent").

 

                                       -10-

<PAGE>

 

            4.2.1 Real Estate Taxes. Tenant shall pay to Landlord, as Additional

Rent, Tenant's Percentage of Taxes (as hereinafter defined) assessed against the

Property (or estimated to be due by governmental authority) for any fiscal tax

period (a "Tax Year") during the term of this Lease (Tenant's Percentage of

Taxes being "Tenant's Tax Obligation"). Upon the request of Tenant, Landlord

shall deliver to Tenant copies of all applicable tax bills and the calculation

of Tenant's Tax Obligation. Except as otherwise provided in the immediately

following paragraph, Tenant shall pay Tenant's Tax Obligation to Landlord at

least thirty (30) days prior to the date or dates within any year during the

term hereof that the same, or any fractional share thereof, shall be due and

payable to any governmental authority responsible for collection of same (as

stated in a notice to Tenant given at least thirty (30) days prior to the date

or dates any such payment shall be due, which notice shall set forth the manner

of computation of Tenant's Tax Obligation due from Tenant), except that such

payment shall be made to Landlord not later than thirty (30) days after such

notice to Tenant, if such notice is given subsequent to the date thirty (30)

days prior to the date the same is due and payable as aforesaid.

 

      Tenant shall pay to Landlord, as Additional Rent on the first day of each

calendar month during the term but otherwise in the manner provided for the

payment of Annual Fixed Rent, estimated payments on account of Tenant's Tax

Obligation, such monthly amounts to be sufficient to provide Landlord by the

time Tax payments are due or are to be made by Landlord a sum equal to Tenant's

Tax Obligation, as reasonably estimated by Landlord from time to time on account

of Taxes for the then current Tax Year. If the total of such monthly remittances

for any Tax Year is greater than Tenant's Tax Obligation for such Tax Year,

Landlord shall credit such overpayment against Tenant's subsequent obligations

on account of Taxes (or promptly refund such overpayment if the term of this

Lease has ended and Tenant has no further obligations to Landlord); if the total

of such remittances is less than Tenant's Tax Obligation for such Tax Year,

Tenant shall pay the difference to Landlord within thirty (30) days after being

so notified by Landlord.

 

      If, after Tenant shall have made all payments due to Landlord pursuant to

this subsection 4.2.1, Landlord shall receive a refund of any portion of Taxes

as a result of an abatement of such Taxes by legal proceedings, settlement or

otherwise, Landlord shall credit to Tenant's subsequent obligations on account

of Taxes (or promptly refund such overpayment if the term of this Lease has

ended and Tenant has no further obligations to Landlord) Tenant's Percentage of

that percentage of the refund (after first deducting any reasonable expenses,

including attorneys', consultants' and appraisers' fees, incurred in connection

with obtaining any such refund) which equals the percentage of the applicable

Tax Year included in the term hereof. In addition to Tenant's rights pursuant to

Mass. Gen Laws Ann. c. 59 Section 59, from time to time, Landlord, in its

reasonable discretion, shall make commercially reasonable efforts to challenge

obvious and materially unfair assessments of Taxes by contesting or objecting to

increases in the determination of the fair market value of the Property.

 

      In the event that the Commencement Date shall occur or the term of this

Lease shall expire or be terminated during any Tax Year, or should the Tax Year

or period of assessment of real estate taxes be changed or be more or less than

one (1) year, or should Tenant's Percentage be modified during any Tax Year due

to a change in the rentable area of the Building and/or the

 

                                      -11-

<PAGE>

 

Premises or otherwise, as the case may be, then the amount of Tenant's Tax

Obligation which may be otherwise payable by Tenant as provided in this

subsection 4.2.1 shall be pro-rated on a daily basis based on a 365 day Tax

Year.

 

      "Taxes" shall mean all taxes, assessments, excises and other charges and

impositions (including penalties and interest only to the extent due to Tenant's

failure to make payments in accordance with this Section 4.2. 1) which are

general or special, ordinary or extraordinary, foreseen or unforeseen, of any

kind or nature which are levied, assessed or imposed at any time during the term

by any governmental authority upon or against or with respect to the Property,

Landlord or the owner or lessee of personal property used by or on behalf of

Landlord in connection with routine maintenance and operation of the Property,

or taxes in lieu thereof, and additional types of taxes to supplement real

estate taxes due to legal limits imposed thereon. If, at any time during the

term of this Lease, any tax or excise on rents or other taxes, however

described, are levied or assessed against Landlord, either wholly or partially

in substitution for, or in addition to, real estate taxes assessed or levied on

the Property, such tax or excise on rents or other taxes shall be included in

Taxes; however, Taxes shall not include franchise, estate, inheritance,

succession, capital levy, income (except to the extent that a tax on income or

revenue is levied solely on rental revenues and not on other types of income and

then only from rental revenue generated by the Property) or excess profits taxes

assessed on Landlord. Taxes also shall include all court costs, attorneys',

consultants' and accountants' fees, and other expenses incurred by Landlord

contesting Taxes through and including all appeals. Taxes shall include any

estimated payment made by Landlord on account of a fiscal tax period for which

the actual and final amount of taxes for such period has not been determined by

the governmental authority as of the date of any such estimated payment.

 

            4.2.2 Operating Costs. Tenant shall pay to Landlord, as Additional

Rent, Tenant's Percentage of Operating Costs (as hereinafter defined) paid or

incurred by Landlord with respect to the Property in any twelve-month period

established by Landlord (an "Operating Year") during the term of this Lease.

Except as otherwise provided in the immediately following paragraph Tenant shall

pay Tenant's Percentage of Operating Costs ("Tenant's Operating Cost

Obligation") to Landlord within twenty (20) days from the date Landlord shall

furnish to Tenant an itemized statement thereof, prepared, allocated and

computed in accordance with then prevailing customs and practices of the real

estate industry, consistently applied. Any year-end statement by Landlord

relating to Operating Costs (other than an invoice for a monthly estimate) shall

be final and binding upon Tenant unless it shall within thirty (30) days after

receipt thereof, contest any item therein by giving notice to Landlord

specifying each item contested and the reasons therefor.

 

      Tenant shall pay to Landlord, as Additional Rent on the first day of each

calendar month during the term but otherwise in the manner provided for the

payment of Annual Fixed Rent, estimated payments on account of Tenant's

Operating Cost Obligation, such monthly amounts to be sufficient to provide to

Landlord, by the end of each Operating Year, a sum equal to the Tenant's

Operating Cost Obligation for such Operating Year, as reasonably estimated by

Landlord from time to time during such Operating Year. If, at the expiration of

each Operating Year in respect of which monthly installments of Operating Cost

Obligation shall have been made as aforesaid, the total of such monthly

remittances is greater than the Tenant's Operating Cost Obligation for such

Operating Year, Landlord shall credit such overpayment against

 

                                      -12-

<PAGE>

 

Tenant's subsequent obligations on account of Operating Costs (or promptly

refund such overpayment if the term of this Lease has ended and Tenant has no

further obligation to Landlord); if the total of such remittances is less than

the Operating Cost Obligation for such Operating Year, Tenant shall pay the

difference to Landlord within ten (10) days after being so notified by Landlord.

 

      In the event that the Commencement Date shall occur or the term of this

Lease shall expire or be terminated during any Operating Year or Tenant's

Percentage shall be modified during any Operating Year due to a change in the

rentable area of the Building and/or the Premises or otherwise, as the case may

be, then the amount of Tenant's Operating Cost Obligation which may be payable

by Tenant as provided in this subsection 4.2.2 shall be pro-rated on a daily

basis based on a 365 day Operating Year.

 

      "Operating Costs" shall include all costs and expenses reasonably paid or

incurred for the operation, cleaning, management, maintenance, repair, upkeep

and security of the Property, including, without limitation:

 

            (a) all salaries, wages, fringe benefits, payroll taxes and

workmen's compensation insurance premiums related thereto and all other costs

paid or incurred with respect to employment of personnel engaged in operation,

administration, cleaning, maintenance, repair, upkeep and security of the

Property including, without limitation, supervisors, property managers,

accountants, bookkeepers, janitors, carpenters, engineers, mechanics,

electricians and plumbers;

 

            (b) all utilities and other costs related to provision of heat

(including oil, steam and/or gas), electricity, air conditioning, and water

(including sewer charges) and other utilities to the Property (exclusive of

reimbursement to Landlord for any of same received as a result of direct billing

to any tenant of the Building);

 

            (c) all costs, including supplies, material and equipment costs, for

cleaning and janitorial services to the common areas of the Property (including,

without limitation, exterior window cleaning), and interior and exterior

landscaping and pest control;

 

            (d) the cost of replacements for tools and other similar equipment

used in the repair, maintenance, cleaning and protection of the Property,

provided that, in the case of any such equipment used jointly on other property

of Landlord, such costs shall be suitably prorated among the Property and such

other properties;

 

            (e) all costs and premiums for fire, casualty, rental income,

liability and such other insurance as may be maintained reasonably from time to

time by Landlord relating to the Property;

 

            (f) all costs of maintaining, repairing, decorating, operating,

administering, inspecting and protecting the Property (including, without

limitation, lighting, installation, maintenance, repair and alteration of signs,

snow removal on the Property and adjacent walks and ways, paving, patching and

restriping of parking areas and operation, maintenance, replacement and repair

of heating, ventilating and air conditioning equipment, fire protection and

security systems, elevators, roofs, parking areas and any other common Building

equipment,

 

                                      -13-

<PAGE>

 

systems or facilities), and all costs of structural and other repairs and

replacements (other than repairs for which Landlord has received full

reimbursement from contractors, other tenants of the Building or from others)

necessary to keep the Property in good working order, repair, appearance and

condition;

 

            (g) costs of compliance with any laws, rules, regulations,

ordinances, agreements or standards applicable to the Building or the Property,

which conformance is not the responsibility of any tenant of the Building, and

which Landlord elects or is required to perform, and costs of testing and

monitoring for any Hazardous Materials (as defined in Section 6.2.8) in the

Building or Property, which is not the responsibility of any tenant of the

Building, and which Landlord elects to perform;

 

            (h) all costs incurred in connection with the administration and

supervision of all matters referred to in items (a) through (g) hereof and in

performing Landlord's obligations under Article 5, including Landlord's office

overhead costs provided that, if any such administrative or supervisory

personnel are also employed on other property of Landlord, such cost of

compensation shall be suitably prorated among the Property and such other

properties;

 

            (i) payments under all service contracts relating to matters

referred to in Items (a) through (h) hereof;

 

            (j) a management fee of three percent (3%) of gross rents payable by

tenants of the Property; and

 

            (k) reasonable attorney's fees and disbursements (exclusive of any

such fees and disbursements incurred in tax abatement proceedings or in the

preparation of leases) and auditing and other professional fees and expenses.

 

      If, after twenty-four months after the Commencement Date and during the

term of this Lease, Landlord shall make any capital expenditure, the total cost

of which is not included in Operating Costs for the Operating Year in which it

was made, Landlord may include in Operating Costs for the Operating Year in

which such expenditure was made and in Operating Costs for each succeeding

Operating Year an annual charge-off of such capital expenditure. Annual

charge-offs shall be equal to the level payments of principal and interest

necessary to amortize the original capital expenditure over the useful life of

the improvement, repair, alteration or replacement made with the capital

expenditure using an interest rate reasonably determined by Landlord as being

the interest rate being charged at the time of the original capital expenditure

for long-term mortgages by institutional lenders on like properties; and the

useful life shall be determined reasonably by Landlord in accordance with then

prevailing customs and practices of the real estate industry, consistently

applied.

 

      Notwithstanding any other contrary provision, Operating Costs shall not

include:

 

                  (i)    the cost of any additions or expansions to the rentable

                        areas of the Property;

 

                  (ii)   any leasehold improvements performed to any premises

                        intended to be occupied by individual tenants;

 

                                      -14-

<PAGE>

 

                  (iii) any reserves for future expenditures not yet incurred;

 

                  (iv)   ground lease rental;

 

                  (v)    costs incurred by Landlord for repair or restoration to

                        the extent that Landlord is reimbursed by insurance or

                        condemnation proceeds or that the same is covered by

                        warranty;

 

                  (vi)   attorneys' fees, leasing commissions and other costs and

                        expenses incurred in connection with negotiations or

                        disputes with present or prospective tenants or other

                        occupants of, or persons, firms or entities with respect

                        to, the Property;

 

                  (vii) expenses in connection with services or benefits that

                         are not offered to Tenant;

 

                  (viii) costs incurred by Landlord due to the negligence or

                        misconduct (including any violation of law) of Landlord

                        or its agents, contractors, licensees and employees or

                        the violation by Landlord or any tenants or other

                        occupants of the terms and conditions of any lease of

                        space or other agreements including this Lease;

 

                   (ix)   interest, principal, points and fees on debts or

                        amortization on any mortgage or mortgages or any other

                        debt instrument encumbering all or any portion of the

                        Property;

 

                   (x)    all items and services for which Tenant or any other

                        tenant reimburses Landlord or that Landlord provides

                        exclusively to one or more tenants (other than Tenant)

                        but not all tenants;

 

                  (xi)   advertising and promotional expenditures in connection

                        with leasing the Property;

 

                  (xii) electric power and any other utility costs for which any

                        tenant or occupant directly contracts with the local

                        public service company;

 

                  (xiii) any costs relating to clean-up of hazardous materials,

                        asbestos and the like;

 

                  (xiv) any charges for depreciation of the Building, fixtures

                        or otherwise; and

 

                  (xv)   the cost of any electric current or other utility

                        furnished to any leasable area of the Building.

 

      In addition, if during any portion of any Operating Year for which

Operating Costs are being computed, less than ninety-five percent (95%) of the

rentable area of the Building was leased to tenants or if Landlord is supplying

less than ninety-five percent (95%) of the rentable

 

                                      -15-

<PAGE>

 

area of the Building with the services and utilities being supplied hereunder,

Landlord may, at its option, reasonably project, on an item-by-item basis, the

Operating Costs that would have been incurred if ninety-five percent (95%) of

the Building were occupied for such Operating Year and such services and

utilities were being supplied to ninety-five percent (95%) of the rentable area

of the Building, and such projected amount shall, for the purposes hereof, be

deemed to be the Operating Costs for such Operating Year.

 

      4.3 Personal Property and Sales Taxes. Tenant shall pay all taxes charged,

assessed or imposed upon the personal property of Tenant and all taxes on the

sales of services or inventory, merchandise and any other goods by Tenant in or

upon the Premises.

 

      4.4 Insurance. Tenant shall, at its expense, take out and maintain,

throughout the tenor of this Lease, the following insurance:

 

            4.4.1 Commercial general liability insurance (on an occurrence basis

and on a 1988 ISO CGL form or its equivalent, including without limitation,

broad form contractual liability, bodily injury, property damage, fire legal

liability, and products and completed operations coverage) under which Tenant is

named as an insured and Landlord and Reit Management and Research LLC (and the

holder of any mortgage on the Premises or Property, as set out in a notice from

time to time) are named (on an ISO Form 20226 or as otherwise acceptable to

Landlord) as additional insureds as their interests may appear, in an amount

which shall, at the beginning of the term, be at least equal to the Commercial

General Liability Insurance Limits, and, which, from time to time during the

term, shall be for such higher limits, if any, as Landlord shall reasonably

determine to be customarily carried in the area in which the Premises are

located at property comparable to the Premises and used for similar purposes;

 

      Worker's compensation insurance with statutory limits covering all of

Tenant's employees working on the Premises; and

 

      So-called "special form" property insurance on a "replacement cost" basis

with an agreed value endorsement covering all furniture, furnishings, fixtures

and equipment and other personal property brought to the Premises by Tenant and

all improvements and betterments to the Premises performed at Tenant's expense.

 

            4.4.2 All such policies shall contain deductibles not in excess of

that reasonably approved by Landlord, shall contain a clause confirming that

such policy and the coverage evidenced thereby shall be primary with respect to

any insurance policies carried by Landlord and shall be obtained from

responsible companies qualified to do business and in good standing in the state

or district in which the Property is located, which companies shall have a

general policy holder's rating of at least A and a financial class of at least

VIII by A.M. Best Company, Inc.. A copy of each paid-up policy evidencing such

insurance (appropriately authenticated by the insurer) or a certificate (on

ACORD Form 27 or its equivalent) of the insurer, certifying that such policy has

been issued and paid in full, providing the coverage required by this Section

and containing provisions specified herein, shall be delivered to Landlord prior

to the commencement of the term of this Lease and, upon renewals, not less than

three (3) days prior to the expiration of such coverage. Each such policy shall

be non-cancelable and not materially changed with respect to the interest of

Landlord and such mortgagees of the Property (and others

 

                                      -16-

<PAGE>

 

that are in privity of estate with Landlord of which Landlord provides notice to

Tenant from time to time) without at least thirty (30) days' prior written

notice thereto. Any insurance required of Tenant under this Lease may be

furnished by Tenant under a blanket policy carried by it provided that such

blanket policy shall reference the Premises, and shall guarantee a minimum limit

available for the Premises equal to the insurance amounts required in this

Lease. Landlord may, at any time, and from time to time, inspect and/or copy any

and all insurance policies required to be procured by Tenant hereunder.

 

             4.4.3 Landlord and Tenant shall each endeavor to secure an

appropriate clause in, or an endorsement upon, each property damage insurance

policy obtained by it and covering the Building, the Premises or the personal

property, fixtures and equipment located therein or thereon, pursuant to which

the respective insurance companies waive subrogation and permit the insured,

prior to any loss, to agree with a third party to waive any claim it might have

against said third party. The waiver of subrogation or permission for waiver of

any claim hereinbefore referred to shall extend to the agents of each party and

its employees and, in the case of Tenant, shall also extend to all other persons

and entities occupying or using the Premises by, through or under Tenant. If and

to the extent that such waiver or permission can be obtained only upon payment

of an additional charge then the party benefiting from the waiver or permission

shall pay such charge upon demand, or shall be deemed to have agreed that the

party obtaining the insurance coverage in question shall be free of any further

obligations under the provisions hereof relating to such waiver or permission

from such insurance companies.

 

      Subject to the foregoing provisions of this Subsection 4.4.3, and insofar

as may be permitted by the terms of the insurance policies carried by it, each

party hereby releases the other with respect to any claim which it might

otherwise have against the other party for any loss or damage, excluding any

deductible amounts, to the extent such damage is actually covered or would have

been covered by policies of insurance required by this Lease to be carried by

the respective parties hereunder. In addition, Tenant agrees to exhaust any and

all claims against its insurer(s) prior to commencing an action against Landlord

for any property loss.

 

      4.5 Utilities. Tenant shall pay all charges related to the supply of

electricity and natural gas to the Premises, whether designated as a charge,

tax, assessment, fee or otherwise, all such charges to be paid as the same from

time to time become due. Except as otherwise provided in this Subsection 4.5 or

in Article 5, it is understood and agreed that Tenant shall make its own

arrangements for the installation or provision of all utilities and services and

that Landlord shall be under no obligation to furnish any utilities to the

Premises.

 

      Tenant acknowledges that Annual Fixed Rent does not include the cost of

supplying electricity or water and sewer service to the Premises. If the utility

serving the Premises shall agree to separate metering, electricity usage shall

be separately metered (and the cost of installing such separate metering shall

be included as part of the Shell and Core Work) and Tenant shall pay all bills

for the supply of electricity to the Premises during the term of this Lease

directly to the utility company furnishing the same. If such separate metering

is not available with respect to the Premises, then Tenant shall, during such

portion of the term as such separate metering is not in effect, pay as

Additional Rent all cost of electricity supplied to the Premises as determined

in good faith by Landlord by submetering or similar device and the cost of

operating, maintaining and repairing (but not installing, which shall be done as

part of the

 

                                      -17-

<PAGE>

 

Shell and Core Work, if applicable) any meter or other device used to measure

Tenant's electrical consumption and any cost incurred by Landlord in keeping

account of or determining Tenant's electrical consumption. Tenant shall pay as

Additional Rent all cost of water and sewer service for the Premises during the

term as determined by Landlord by submetering or other similar device and the

cost of operating, maintaining and repairing (but not installing, which shall be

done as part of the Shell and Core Work) any meter or other device used to

measure water consumption and any cost incurred by Landlord in keeping account

of or determining Tenant's water consumption. Alternatively, at Landlord's

option, Tenant shall pay Tenant's Percentage of the charges for electricity

service and/or the charges for water and sewer service during the term allocable

to those portions of the Building leased or intended to be leased to tenants,

within ten days of invoice therefor, provided however if some or all of the

areas leased or intended to be leased to tenants are separately metered for

electricity and/or water, such Tenant's Percentage for purposes of this

Subsection 4.5 only shall be determined by dividing the rentable area of the

Premises by the rentable area of the portions of the Building not separately

metered for such service.

 

      4.6 Late Payment of Rent. If any installment of Annual Fixed Rent or any

Additional Rent is not paid on or before the date the same is due, it shall bear

interest (as Additional Rent) from the date due until the date paid at the

Default Rate (as defined in Section 8.4). In addition, if any installment of

Annual Fixed Rent or Additional Rent is unpaid for more than ten (10) days after

the date due, Tenant shall pay to Landlord a late charge equal to the greater of

One Hundred Dollars ($100) or three percent (3%) of the delinquent amount. The

parties agree that the amount of such late charge represents a reasonable

estimate of the cost and expense that would be incurred by Landlord in

processing and administration of each delinquent payment by Tenant, but the

payment of such late charges shall not excuse or cure any default by Tenant

under this Lease. Absent specific provision to the contrary, all Additional Rent

shall be due and payable in full ten (10) days after demand by Landlord.

 

      4.7 Security Deposit. Upon execution of this Lease, Tenant shall deposit

with Landlord the Security Deposit. The Security Deposit shall be held by

Landlord as security for the faithful performance of all the terms of this Lease

to be observed and performed by Tenant. The Security Deposit shall not be

mortgaged, assigned, transferred or encumbered by Tenant and any such act on the

part of Tenant shall be without force and effect and shall not be binding upon

Landlord. Tenant shall cause the Security Deposit to be maintained throughout

the term in the amount set forth in Section 1.1, subject to reduction as

hereinafter provided. The Security Deposit shall be reduced to $350,000 as of

the first anniversary of the Rent Commencement Date, to $250,000 as of the

second anniversary of the Rent Commencement Date, to $150,000 as of the third

anniversary of the Rent Commencement Date, and to $100,000 as of the fourth

anniversary of the Rent Commencement Date; provided, however, that no reduction

in the Security Deposit shall occur once there shall have existed a Default of

Tenant as defined in Section 8.1.

 

      Tenant shall have the right to post the Security Deposit in the form of a

letter of credit (the "Letter of Credit"), which shall (a) be unconditional and

irrevocable and otherwise in form and substance reasonably satisfactory to

Landlord; (b) permit multiple draws; (c) be issued by a commercial bank

reasonably acceptable to Landlord from time to time; (d) be made payable to, and

expressly transferable and assignable at no charge by, Landlord but only to the

holder from

 

                                      -18-

<PAGE>

 

time to time of the interest of Landlord under this Lease (and if the issuer

shall impose a charge for transfer, Tenant shall pay such charge); (e) be

payable at sight upon presentment of a sight draft accompanied by a certificate

of Landlord stating either that Tenant is in default under this Lease or that

Landlord is otherwise permitted to draw upon such Letter of Credit under the

express terms of this Lease, and the amount that Landlord is owed (or is

permitted to draw) in connection therewith; and (f) either expire not earlier

than ninety (90) days following the expiration of the tern of this Lease, or be

replaced not less than thirty (30) days prior to the expiration of the then

current Letter of Credit so that the original Letter of Credit or a replacement

thereof shall be in full force and effect throughout the term of this Lease and

for a period of at least ninety (90) days thereafter. Tenant shall maintain the

Letter of Credit in the amount of the Security Deposit as the same may be

reduced as provided above and shall deliver to Landlord any replacement Letter

of Credit not less than thirty (30) days prior to the expiration of the then

current Letter of Credit. Any reduction in the amount of the Letter of Credit

may be accomplished by Landlord's surrender of the existing Letter of Credit in

return for Landlord's contemporaneous receipt of a new Letter of Credit in the

lower amount. Notwithstanding anything in this Lease to the contrary, any grace

period or cure periods which are otherwise applicable under Section 8.1 hereof,

shall not apply to any of the foregoing, and, specifically, if Tenant fails to

comply with the requirements of subsection (f) above or if Tenant shall fail to

maintain the Letter of Credit in the full amount of the Security Deposit after

any draw thereon by Landlord,. Landlord shall have the immediate right to draw

upon the Letter of Credit in full and hold the proceeds thereof as a cash

security deposit. Each Letter of Credit shall be issued by a commercial bank

that has a credit rating with respect to certificates of deposit, short term

deposits or commercial paper of at least P-2 (or equivalent) by Moody's Investor

Service, Inc., or at least A-2 (or equivalent) by Standard & Poor's Corporation.

If the issuer's credit rating is reduced below P-2 (or equivalent) by Moody's

Investor Service, Inc., or at least A-2 (or equivalent) by Standard & Poor's

Corporation, or if the financial condition of the issuer changes in any other

materially adverse way, then Landlord shall have the right to require that

Tenant obtain from a different issuer a substitute Letter of Credit that

complies in all respects with the requirements of this Section, and Tenant's

failure to obtain such substitute Letter of Credit within twenty (20) days after

Landlord's demand therefor (with no other notice, or grace or cure period being

applicable thereto) shall entitle Landlord immediately to draw upon the existing

Letter of Credit in full, without any further notice to Tenant. Landlord may

use, apply or retain the proceeds of the Letter of Credit to the same extent

that Landlord may use, apply or retain any cash security deposit, as set forth

herein. If Landlord draws against the Letter of Credit and uses or applies the

proceeds as Landlord could apply the Security Deposit in accordance with this

Lease, Tenant shall, within ten (10) days after notice from Landlord, provide

Landlord with either an additional Letter of Credit in the amount so drawn or an

amendment to the existing Letter of Credit restoring the amount thereof to the

amount initially provided. Tenant hereby agrees to cooperate promptly, at its

expense with Landlord to execute and deliver to Landlord any modifications,

amendments and replacements of the Letter of Credit, as Landlord may reasonably

request to carry out the terms and conditions hereof.

 

      If the Annual Fixed Rent or Additional Rent payable hereunder shall be

overdue and unpaid or should Landlord make any payment on behalf of the Tenant,

or Tenant shall fail to perform any of the terms of this Lease, then Landlord

may, at its option and without notice or prejudice to any other remedy which

Landlord may have on account thereof, appropriate and apply the entire Security

Deposit or so much thereof as may be necessary to compensate

 

                                       -19-

<PAGE>

 

Landlord toward the payment of Annual Fixed Rent, Additional Rent or other sums

or loss or damage sustained by Landlord due to such breach by Tenant; and Tenant

shall forthwith upon demand restore the Security Deposit to the amount stated in

Section 1.1. Notwithstanding the foregoing, upon the application by Landlord of

all or any portion of the Security Deposit (with or without notice thereof to

Tenant) to compensate Landlord for a failure by Tenant to pay any Annual Fixed

Rent or Additional Rent when due or to perform any other obligation hereunder,

and until Tenant shall have restored the Security Deposit to the amount required

by Section 1.1, Tenant shall be deemed to be in default in the payment of

Additional Rent for purposes of Section 8.l(a)(I) hereof. So long as Tenant

shall not be in default of its obligations under this Lease, Landlord shall

return the Security Deposit, or so much thereof as shall have not theretofore

been applied in accordance with the terms of this Section 4.7 (and less any

amounts Landlord shall estimate shall be due from Tenant following year-end

reconciliation of Operating Costs and Taxes) to Tenant promptly following the

expiration or earlier termination of the term of this Lease and the surrender of

possession of the Premises by Tenant to Landlord in accordance with the terms of

this Lease. While Landlord holds the Security Deposit, Landlord shall have no

obligation to pay interest on the same and shall have the right to commingle the

same with Landlord's other funds. If Landlord conveys Landlord's interest under

this Lease, the Security Deposit, or any part thereof not previously applied,

shall be turned over by Landlord to Landlord's grantee, and Tenant shall look

solely to such grantee for proper application of the Security Deposit in

accordance with the terms of this Section 4.7 and the return thereof in

accordance herewith. The holder of a mortgage on the Property shall not be

responsible to Tenant for the return or application of the Security Deposit,

whether or not it succeeds to the position of Landlord hereunder, unless such

holder actually receives the Security Deposit.

 

                                    ARTICLE 5

 

                              Landlord's Covenants

 

      5.1 Affirmative Covenants. Landlord shall, during the term of this Lease

provide the following:

 

            5.1.1 Heat and Air-Conditioning. Landlord shall maintain the central

Building heat, ventilation and air-conditioning equipment ("HVAC") to provide

outside air and chilled and heated water to a central area in the Premises.

Tenant shall pay, as Additional Rent, all charges (which charges shall include

costs of utilities and maintenance and repair costs) incurred by Landlord to

supply HVAC to the Premises, and Landlord shall substantiate the basis of such

charges using customary industry practices.

 

            5.1.2 Landscaping. Landlord shall provide cleaning, maintenance and

landscaping to the common areas of the Building and Property (including snow

removal to the extent necessary to maintain reasonable access to the Building

and the parking lot) in accordance with standards generally prevailing

throughout the term hereof in comparable office buildings in the Route 128 area.

 

            5.1.3 Elevator, Lighting and Electricity. Landlord shall furnish

non-exclusive elevator service to the Premises; purchase and install, at

Tenant's expense, all lamps, tubes, bulbs, starters and ballasts for lighting

fixtures in the Premises; provide lighting to public and

 

                                       -20-

<PAGE>

 

common areas of the Property; and arrange for the supply of electrical power to

the Premises to accommodate a load not exceeding the limitations contained in

Section 6.2.4.

 

            5.1.4 Repairs. Except as otherwise expressly provided herein,

Landlord shall promptly and professionally make such repairs and replacements to

the roof, exterior walls, floor slabs and other structural components of the

Building, and to the common areas and facilities of the Building (including any

common area plumbing, electrical and HVAC equipment, elevators and any other

common equipment or systems in the Building) as may be necessary to keep them in

good repair and condition (exclusive of equipment installed by Tenant and except

for those repairs required to be made by Tenant pursuant to Subsection 6.1.3

hereof and repairs or replacements occasioned by any act or negligence of

Tenant, its servants, agents, customers, contractors, employees, invitees, or

licensees).

 

      5.2 Interruption. Landlord shall have no responsibility or liability to

Tenant for failure, interruption, inadequacy, defect or unavailability of any

services, facilities, utilities, repairs or replacements or for any failure or

inability to provide access or to perform any other obligation under this Lease

caused by breakage, accident, fire, flood or other casualty, strikes or other

labor trouble, order or regulation of or by any governmental authority,

inclement weather, repairs, inability to obtain or shortages of utilities,

supplies, labor or materials, war, civil commotion or other emergency,

transportation difficulties or due to any act or neglect of Tenant or Tenant's

servants, agents, employees or licensees or for any other cause beyond the

reasonable control of Landlord, and in no event shall Landlord be liable to

Tenant for any indirect or consequential damages suffered by Tenant due to any

such failure, interruption, inadequacy, defect or unavailability; and failure or

omission on the part of Landlord to furnish any of same for any of the reasons

set forth in this paragraph shall not be construed as an eviction of Tenant,

actual or constructive, nor entitle Tenant to an abatement of rent, nor render

the Landlord liable in damages, nor release Tenant from prompt fulfillment of

any of its covenants under this Lease.

 

      Landlord reserves the right to deny access to the Building and to

interrupt the services of the HVAC, plumbing, electrical or other mechanical

systems or facilities in the Building when necessary from time to time by reason

of accident or emergency, or for repairs, alterations, replacements or

improvements which in the reasonable judgment of Landlord are desirable or

necessary, until such repairs, alterations, replacements or improvements shall

have been completed. Landlord shall use reasonable efforts to minimize the

duration of any such interruption and to give to Tenant at least three (3) days'

notice if service is to be interrupted, except in cases of emergency.

 

      5.3 Outside Services. In the event Tenant wishes to obtain services or to

hire vendors relating to the Premises, Tenant shall first obtain the prior

approval of Landlord for the installation and/or utilization of such services or

vendors. Landlord's approval may not be withheld, conditioned or delayed

unreasonably. Such services shall include, but shall not be limited to, utility

providers, security services, moving services, equipment servicers and

installers, catering services and the like. Notwithstanding any Landlord

approval of the installation and/or utilization of such services or vendors,

such installation and utilization shall be at Tenant's sole cost, risk and

expense.

 

      5.4 Access to Building. During Normal Building Operating Hours, the

Building

 

                                       -21-

<PAGE>

 

shall, subject to the provisions of Section 5.2, be open and access to the

Premises shall be freely available, subject to the Rules and Regulations. During

periods other than Normal Building Operating Hours, Tenant shall have access to

the Premises, but such access shall also be subject to the Rules and

Regulations. Tenant acknowledges that Tenant is responsible for providing

(subject to the terms of this Lease) such security to and for its property and

personnel in the Premises as it deems appropriate.

 

      5.5 Parking. During the term of this Lease, Landlord shall provide Tenant

with access to parking spaces on the Property as follows:

 

            (a) Tenant shall be entitled to 3.6 parking spaces per 1,000 square

feet of Premises Rentable Area, rounded down to the nearest whole number. All

such parking spaces shall be unreserved and available on a first-come,

first-served basis, except that six (6) spaces, in the location shown on Exhibit

A-1, shall be identified as reserved for Tenant's visitors.

 

            (b) Tenant shall use such parking spaces solely for the parking of

passenger vehicles of Tenant and Tenant's employees, business invitees and

guests only.

 

            (c) Landlord reserves the right to implement and modify systems to

regulate access to and use of the parking spaces, including, without limitation,

parking passes, parking stickers and card key access, or any other system

reasonably designated by Landlord.

 

            (d) Tenant hereby indemnifies and shall defend and hold Landlord

harmless form and against all claims, loss, cost or damage arising out of the

use by Tenant and Tenant's employees and invitees of the parking spaces, except

to the extent caused by the willful misconduct or gross negligence of Landlord

or Landlord's agent or employees.

 

      5.6 Compliance with Americans with Disabilities Act. As of the

Commencement Date, the common areas of the Property shall, to Landlord's

knowledge, be in material compliance with the Americans with Disabilities Act of

1990, as amended and all other applicable laws and regulations concerning access

to and use of facilities like the Building by people with disabilities,

including without limitation, the Massachusetts Architectural Business Board

regulations (collectively, the "ADA"). If during the term of this Lease any

improvement or alteration to the common areas of the Property is necessary for

compliance with the ADA and the obligation to make such improvement or

alteration is not Tenant's pursuant to Sections 6.1.3, 6.1.4 or 6.2.5, Landlord

shall make such required improvement or alteration.

 

      5.7 Hazardous Waste Representation and Covenants. Landlord has previously

delivered to Tenant reports dated December 15, 1995 and April 10, 1998 by Rizzo

Associates, Inc. and Dames & Moore respectively with respect to certain

environmental conditions at the Property and a Phase I and Downgradient Property

Status Report of Haley & Aldrich dated August 1, 1997 with respect to 91

Hartwell Avenue. So long as the condition requiring removal or remediation of

Hazardous Materials is not caused by Tenant or any party for whom Tenant is

responsible, Landlord shall, in a manner that complies with all applicable

Environmental Laws, perform or cause others to perform all remediation necessary

to cause the Property to comply with Environmental Laws. Landlord shall

indemnify and defend (with counsel reasonably acceptable to Tenant) Tenant from

any liability for fines or penalties arising from or related to a

 

                                       -22-

<PAGE>

 

breach by Landlord of the forgoing representations and agreements of Landlord

(including also costs incurred to avoid the imposition of, or to discharge, any

lien on the Property arising from any such breach) and from any liability for

costs of removing or remediating Hazardous Materials which Landlord is obligated

to remediate pursuant to this paragraph.

 

      5.8 Indemnification. Subject to all limitations, waivers, exclusions and

conditions contained in this Lease (each of which shall control in the event of

any conflict or inconsistency with this Section 5.8), Landlord shall defend and

indemnify Tenant and its directors, officers, agents and employees against and

from any and all claims, liabilities or penalties asserted by or on behalf of

any third party on account of personal injury arising out of the negligence or

other wrongful conduct of Landlord or its agents, contractors or employees

during the term of this Lease. In case of any action or proceeding brought

against Tenant by reason of any such claim, Landlord, upon notice from Tenant,

shall resist or defend such action or proceeding and employ counsel therefor

reasonably satisfactory to Tenant. Notwithstanding the foregoing in no event

shall this Section 5.8 require Landlord to indemnify or defend Tenant or its

employees or Tenant's agents or their employees against any loss, cost, damage,

liability, claim, or expense to the extent arising out of the negligence or

misconduct of Tenant or its employees or contractors or Tenant's agents or their

employees.

 

                                    ARTICLE 6

 

                          Tenant's Additional Covenants

 

      6.1 Affirmative Covenants. Tenant shall do the following:

 

            6.1.1 Perform Obligations. Tenant shall perform promptly all of the

obligations of Tenant set forth in this Lease; and pay when due the Annual Fixed

Rent and Additional Rent and all other amounts which by the terms of this Lease

are to be paid by Tenant.

 

            6.1.2 Use. Tenant shall, during the term of this Lease, use the

Premises only for the Permitted Uses and from time to time, procure and

maintain, and at Landlord's request provide to Landlord copies of, all licenses

and permits necessary therefor and for any other use or activity conducted at

the Premises, at Tenant's sole expense. Tenant shall also provide to Landlord

access to all Material Safety Data Sheets on any Hazardous Materials in the

Prem


 
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