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FIRST AMENDMENT AND WAIVER

Forbearance Agreement

FIRST AMENDMENT AND WAIVER | Document Parties: OMRIX BIOPHARMACEUTICALS, INC. | Johnson & Johnson Development Corporation You are currently viewing:
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OMRIX BIOPHARMACEUTICALS, INC. | Johnson & Johnson Development Corporation

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Title: FIRST AMENDMENT AND WAIVER
Governing Law: Delaware     Date: 1/18/2006
Industry: Biotechnology and Drugs     Sector: Healthcare

FIRST AMENDMENT AND WAIVER, Parties: omrix biopharmaceuticals  inc. , johnson & johnson development corporation
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                                                                    Exhibit 4.12

                           FIRST AMENDMENT AND WAIVER


         FIRST AMENDMENT AND WAIVER, dated as of January 13, 2005, (this
"Amendment and Waiver"), between Omrix Biopharmaceuticals, Inc., a Delaware
corporation (the "Company") and Johnson & Johnson Development Corporation
("JJDC").

         WHEREAS, the Company issued to JJDC that certain Common Stock Purchase
Warrant, dated August 11, 2004 (the "Warrant") represented by Certificate no.
JJ-1, whereby JJDC is entitled to purchase, subject to the terms and conditions
set forth therein, an aggregate of up to One Hundred Thousand (100,000) shares
(subject to adjustment as provided therein) of common stock, par value $.10 per
share (the "Common Stock"), of the Company at a purchase price of $12.29 per
share (subject to adjustment as set forth therein, the "Exercise Price"),
payable as provided therein. Capitalized terms used but not otherwise defined
herein have the meanings assigned to them in the Warrant; and

         WHEREAS, the Company proposes to enter into a transaction (the
"Recapitalization") pursuant to which the holders of (i) the Company's senior
subordinated convertible promissory notes (the "1998/1999 Notes") and warrants
issued in connection with the issuance of the 1998/1999 Notes, (ii) the
Company's senior secured convertible promissory notes issued in September 2002
to refinance certain notes issued by the Company in 2001, (iii) additional
senior secured convertible promissory notes of the Company issued in September
2002 and (iv) the Company's Series A Convertible Preferred Stock and Series B
Convertible Preferred Stock will convert such securities into and/or exchange
such securities for Common Stock of the Company; and

         WHEREAS, the Company and JJDC desire to amend certain provisions of the
Warrant in connection with the Recapitalization;

         NOW,


 
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