Re: Closing of Term Loan

Exhibit 10.17

February 28, 2003

Applied Precision, LLC

1040 12th Avenue NW

Issaquah, WA 98027-8929

Gentlemen:

We refer to the Secured Promissory Note dated as of even date herewith made payable to the undersigned in the original principal amount of $522,215.00 (the “ Note ”). All capitalized terms used without definition herein shall have the meanings ascribed to such terms in the Note.

Borrow agrees to pay Lakeside a closing fee in the amount of $10,000.

The Note provides that an Event of Default under and as defined in the SVB Credit Agreement