Re: Purchase of a $2,300,000 Secured Original Issue Discount Debenture (the " Debenture "), Common Stock Put Option, and a Warrant to purchase shares of the Common Stock of Cord Blood America, INC., a Nevada corporation (the " Company "), by SHELTER ISLAND OPPORTUNITY FUND, LLC (the " Purchaser ")

Fee Agreement

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This Fee Agreement involves

Cord Blood America, Inc | Midway Management Partners, LLC | SHELTER ISLAND OPPORTUNITY FUND, LLC

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Title: Re: Purchase of a $2,300,000 Secured Original Issue Discount Debenture (the " Debenture "), Common Stock Put Option, and a Warrant to purchase shares of the Common Stock of Cord Blood America, INC., a Nevada corporation (the " Company "), by SHELTER ISLAND OPPORTUNITY FUND, LLC (the " Purchaser ")
Date: 2/20/2007

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Exhibit 10.109

February 14, 2007

Cord Blood America, Inc.

Re:

Purchase of a $2,300,000 Secured Original Issue Discount Debenture (the “Debenture”), Common Stock Put Option, and a Warrant to purchase shares of the Common Stock of Cord Blood America, INC., a Nevada corporation (the “Company”), by SHELTER ISLAND OPPORTUNITY FUND, LLC (the “Purchaser”)

Ladies and Gentlemen:

The Company shall pay Midway Management Partners, LLC, a Delaware limited liability company (the “Management Company”), a collateral monitoring fee, on a quarterly basis, payable on each of March 31, June 30, September 30 and December 31, in an amount equal to 0.25% of the amount of principal outstanding under the Debenture. Whenever any amount expressed to be due by the terms of this letter is due on any day which is not a business day, the same shall instead b

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