Proprietary Information and Inventions Agreement

Executive Employment Agreement

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Title: Proprietary Information and Inventions Agreement
Date: 8/8/2005
Industry: SCIINS

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[LOGO ILLUMINA]

Exhibit 10.33

April 26, 2005

Christian Henry

Re: Illumina, Inc.

Dear Christian;

It gives me great pleasure to set forth the principal terms for you to join

Illumina, Inc. (the "Company").

Position: VP and Chief Financial Officer

Responsibilities: The VP and Chief Financial Officer is a position of both

strategic and functional leadership having primary

responsibility for the overall financial activities of

the Company as well as being involved in the architecture

of the Company's financial and business vision. Principal

responsibilities include:

- Participating as a key member of the management team

in corporate strategic planning,

- Developing the financial goals and strategy of the

company,

- Providing management and financial reporting to the

operating groups of the company,

- Ensuring the company is well funded through an

appropriate combination of equity and debt

financings,

- Leading the annual financial planning process,

- Over time, developing as a key contact for Wall

Street analysts and investors,

- Implementing the financial aspects of the company's

ERP system,

- Maximizing the return on investment of the company's

cash resources while maintaining a suitable risk

profile,

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- Assuming a leadership role in corporate