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EMPLOYMENT AGREEMENT

Executive Employment Agreement

EMPLOYMENT AGREEMENT | Document Parties: MDRNA, Inc | Nastech Pharmaceutical Company Inc You are currently viewing:
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MDRNA, Inc | Nastech Pharmaceutical Company Inc

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Title: EMPLOYMENT AGREEMENT
Governing Law: Washington     Date: 6/13/2008
Industry: Biotechnology and Drugs     Sector: Healthcare

EMPLOYMENT AGREEMENT, Parties: mdrna  inc , nastech pharmaceutical company inc
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Exhibit 10.1
EMPLOYMENT AGREEMENT
     This Employment Agreement (this “Agreement”), is executed and entered into on the 10th day of June, 2008 (the “Transition Date”) by and between MDRNA, Inc. (the “Company”), a Delaware corporation formerly known as Nastech Pharmaceutical Company Inc., having offices at 3450 Monte Villa Parkway, Bothell, Washington, and Steven C. Quay, M.D., Ph.D. (“Executive”). This agreement shall be effective as and to the extent specified in Section 1 hereof.
W I T N E S S E T H:
     WHEREAS, the Company and Executive have executed and entered into a number of prior employment agreements, including an agreement dated December 16, 2005 (the “December 2005 Agreement”), which specifies an employment term scheduled to end at the close of business on December 31, 2009; and
     WHEREAS, the Company and Executive desire to extend and modify the employment relationship between them prospectively as set forth herein;
     NOW THEREFORE, in consideration of the mutual promises and agreements herein and for other good and valuable consideration the receipt and sufficiency of which are hereby mutually acknowledged, the Company and Executive agree as follows:
     1.  Application and Effectiveness of Agreements . This Agreement shall govern (i) the employment relationship between the Company and Executive from and after the Transition Date and (ii) other matters as set forth herein. Nevertheless, to the extent their provisions concern matters not addressed in this Agreement, the December 2005 Agreement and, as applicable, prior agreements between the Company and Executive shall continue to govern the employment of Executive by the Company prior to the Transition Date and matters directly relating to such employment prior to the Transition Date. Without limiting the foregoing, the prior agreements shall continue to govern the continued vesting and effectiveness, after the Transition Date, of stock options for, and restricted shares of, Company stock granted to Executive under those prior agreements .
     2.  Employment; Responsibilities and Authority; Board Designees; Outside Activities
          (a) Subject to the terms and conditions of this Agreement, the Company shall continue to employ Executive after the Transition Date and during the Employment Period (as defined in Section 3, below); and Executive shall have the positions and titles of Chairman of the Board of Directors of the Company (the “Board”), Chairman of the Company’s Science Advisory Board, and Chief Scientific Officer of the Company. In these positions, Executive (i) shall perform such acts and duties and furnish such services to the Company and its Subsidiaries (as defined below) as the Board shall from time to time reasonably direct and (ii) shall have general and strategic charge and oversight of the scientific direction of the Company, including its research and development initiatives and activities, subject to the authority and control of the Board. All scientific and research personnel employed by the Company shall report to Executive. Until the appointment by the Company of an executive as chief executive officer, Executive shall also hold the title of, and act as, Chief Executive Officer. Executive agrees he

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shall resign such title upon the Company’s appointment of another individual as chief executive officer.
          (b) During the Employment Period, the Company shall: (i) continue to take such actions as may be necessary to cause the nomination and recommendation of Executive for election as a director and as Chairman of the Board and (ii) use all best efforts to cause Executive to be elected to and retained in those positions. Following termination of Executive’s employment, at such time as Executive should own fewer than 400,000 shares of stock of the Company, Executive shall resign from the Board and shall be deemed immediately for all purposes to have resigned from the Board.
          (c) Subject to the terms and conditions of this Agreement, Executive hereby accepts such employment and agrees to devote his full time and best efforts to the duties provided herein, subject to the further provisions and limited exception set forth below in Section 2(d).
          (d) Pursuant to Section 2(c) of the December 2005 Agreement and prior agreements, the Executive could engage in certain business, research, professional, and other activities unrelated to the Company (collectively, “Other Activities”), during his employment. All intellectual property arising from Other Activities not currently owned by the Company is referred to as “Other IP”. The Company and Executive hereby agree that, during the Employment Period, the Executive shall not pursue any areas of research or development activities except solely for the Company and that any inventions and developments made by him during the Employment Period are and shall be owned solely by the Company. This Section 2(d) governs the disposition of Other IP.
          (i) Other IP that is not medical/health science in nature shall be owned by Executive. The Executive shall not devote more than relatively de minimis time or efforts to such Other IP with the objective, in any such time and efforts, of arranging for the licensing, further development, and exploitation of such Other IP by others, with all net profits with respect thereto the property of Executive.
          (ii) Other IP that is medical/health science in nature shall be divided into two categories in accordance with the procedures stated in clause (iii) below:
     (a) The first category is Other IP that is medical/health science in nature and which is within the Business of the Company. Such Other IP shall be owned by and developed solely by the Company for the Company’s benefit.
     (b) The second category is Other IP that is medical/health science in nature and which is not within the Business of the Company. Such Other IP shall be owned by Executive. The Executive shall not devote more than relatively de minimis time or efforts to such Other IP with the objective, in any such time and efforts, of arranging for the licensing, further development, and exploitation of such Other IP by others, provided that if net profits are realized by Executive (after all associated costs and expenses accrued, paid, or incurred have been recovered and any on-going costs and expenses covered) from such licensing or similar arrangements as to such Other IP, such net profits will be divided as

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follows: 60% to Executive and 40% to the Company; provided further that if (x) the Company terminates the employment of Executive prior to December 31, 2013 without Cause (as defined below), (y) Executive terminates his employment prior to December 31, 2013 for Good Reason (as defined below), or (z) a Change in Control as stated in Section 21 takes place, such net profits will thereafter be divided as follows: 100% to Executive and 0% to the Company or its successor.
               (iii) All determinations whether Other IP is (a) not medical/health science in nature, (b) medical/health science in nature, and (c) if medical/health science in nature, within or without the Business of the Company, shall be made by the IP Panel (as defined below) in good faith. Executive shall disclose to the IP Panel all Other IP, and the IP Panel shall then make a prompt determination whether such Other IP is medical/health science in nature, and within or without the Business of the Company. The “IP Panel” shall mean a panel composed of Executive, the Lead Independent Director of the Board, and a director chosen by the Lead Independent Director following consultation with the Executive. The Company and the Executive acknowledge that all inventions and developments made by Executive prior to the commencement of his employment by the Company on August 9, 2000 are the sole property of Executive (“Prior IP”). At the request of the Executive, from time to time the IP Panel will confirm whether specified intellectual property constitutes Prior IP. The IP Panel is not a committee of the board of directors nor a corporate governance mechanism but simply a mechanism created by this Agreement. The determinations of the IP Panel shall be final and non-appealable.
          (e) For purposes of the foregoing, the “Business of the Company,” from time to time means the Company’s business as is described in Part I, Item 1 (“Description of Business”) of the Company’s then most recent Annual Report on Form 10-K filed with the United States Securities and Exchange Commission and the Company’s intended business(es) as determined by the Board or the IP Panel as applicable; and the term “Subsidiary” means a corporation or other entity that is at least majority owned, directly or indirectly, by the Company.
     3.  Term; Employment Period . The “Employment Period” under this Agreement shall commence on the Transition Date and shall terminate at the close of business on December 31, 2013 unless it is (a) extended by written agreement between the parties or by continuing employment of Executive by the Company as provided in the following sentence or (b) earlier terminated pursuant to Section 11 hereof. If Executive shall remain in substantially full-time employment by the Company beyond what would otherwise be the end of the Employment Period without any further written agreement between the parties as to such employment, the Employment Period shall be deemed to continue on a month-to-month basis and either party shall have the right to terminate Executive’s employment hereunder at the end of any ensuing calendar month on written notice of at least 30 days.
     4.  Salary . For services rendered to the Company during the Employment Period, the Company shall compensate Executive with a base salary, payable in bi-weekly installments, which shall be $500,000 per annum for the period from the Transition Date through the end of calendar year 2008 and which shall be increased by up to five percent (5%) effective on January 1 of each calendar year beginning with 2009 during the Employment Period, with the actual amount of such increase to be determined by the Board or the Compensation Committee in good faith prior to the beginning of each such calendar year.

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     5.  Incentive Cash Compensation
          (a) For the Company’s fiscal year that began on January 1, 2008, Executive shall receive incentive cash compensation for the period up to and including June 9, 2008 as and to the extent provided for such prorated year in the December 2005 Agreement as if that agreement remained in effect in all respects. For the remainder of the Company’s fiscal year that began on January 1, 2008 and Company’s subsequent fiscal years or portions thereof during the remainder of the Employment Period, Executive shall be eligible to receive incentive cash compensation of up to fifty percent (50%) of Executive’s base salary for such year, as determined by the Board or the Compensation Committee based on their good faith assessment of Executive’s performance in such year in relation to the actual needs of the Company in such year and in relation to any performance areas and/or performance targets as shall have been determined by the Board or the Compensation Committee after consultation with Executive as described below, provided , however , that the Executive and the Company acknowledge that the amount actually paid to the Executive pursuant to this Section 5 for any fiscal year or portion thereof may be nil, or may be more or less than said targeted amount.
          (b) The Company and Executive shall periodically discuss and attempt in good faith to agree upon performance criteria for determination of the incentive cash compensation that will be payable to Executive with respect to each fiscal year of the Company, or portion thereof, beginning on or after June 10, 2008. To the extent possible, such agreement shall be made, as to each such period, prior to the end of the second month following such period.
          (c) As soon as practical, and in any event no later than ninety (90) days, after the end of each fiscal year of the Company, the Compensation Committee or the Board, in consultation with Executive, shall determine, reasonably and in good faith, the amount of incentive cash compensation for Executive for such year and shall cause such amount to be paid to Executive forthwith. If unforeseen developments shall have occurred that made any performance areas and/or performance targets previously determined unachievable, infeasible, or inadvisable — and therefore inappropriate as a measure of the performance of Executive — the Compensation Committee or the Board shall consider in good faith the extent to which the incentive cash compensation shall nevertheless be paid to Executive based on his performance.
          (d) Except as otherwise provided herein or in a future agreement between Executive and the Company, for any fiscal year that begins before, but ends after, the end of the Employment Period, a pro-rated annual bonus shall be payable to Executive based on the portion of such fiscal year that shall have elapsed to the end of the Employment Period, the methodology referred to above, and the reasonable, good faith determination of the Compensation Committee or the Board of Executive’s performance during such period.
     6.  New Stock Options . As further compensation, and in addition to the stock options and restricted shares that have been granted to Executive under prior agreements with the Company (which are not affected by this Agreement, remain outstanding, and, to the extent not vested as of the Transition Date, shall continue to vest and become exercisable in accordance with their terms after the Transition Date), the Company hereby grants to Executive, as incentive compensation for service on and after the Transition Date, new options to purchase additional shares of common stock of the Company (the “New Options”) as follows:

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          (a) All of the New Options are granted on the Transition Date and have a term of 10 years, running from the Transition Date.
          (b) Among the New Options, options for the maximum permissible number of shares are Incentive Stock Options (“ISOs”) for purposes of the Internal Revenue Code of 1986, as amended, and the regulations thereunder (together, the “Tax Laws”). Those ISOs are among the New Options referred to as vesting in each of the five installments provided for in Section 6(d), below, with the numbers of shares for which such ISOs in each of those installments will be exercisable having been determined in such a manner as to maximize the total number of shares as to which such tax advantaged treatment is available; and the ISOs shall vest and become first exerciseable at the times and under the conditions for each such installment, respectively. The remainder of the New Options in each of the five installments are non-statutory stock options.
          (c) The exercise prices of the New Options included in each of the five installments provided for in Section 6(d) below and the numbers of shares that may be purchased upon exercise of such New Options (i) are set forth in the respective sub-paragraphs of Section 6(d) and (ii) will be subject to the anti-dilution adjustments provided for by the option granting documents.
          (d) The New Options, in the aggregate, grant the right to purchase a total of One Million Seven Hundred Thousand (1,700,000) shares of common stock of the Company (subject to potential adjustments as provided for above), and they shall vest and become exerciseable as follows (or as expressly stated elsewhere in this Agreement in the event of certain circumstances and events provided for herein):
  -   New Options for Four Hundred Twenty Thousand (420,000) shares (some of which are ISOs and some of which are non-statutory stock options, as provided above) will vest and become exercisable on June 10, 2009 and all of those New Options have a per-share exercise price equal to the fair market value of a share of the Company’s stock on the Transition Date (the “Execution Strike Price”);
 
  -   New Options for 105,000 shares (some of which are ISOs and some of which are non-statutory stock options, as provided above) shall vest and become exercisable on each of September 10, 2009, December 10, 2009, March 10, 2010 and June 10, 2010 (for an aggregate 420,000 options during such period) at the Execution Strike Price plus $1.00, if Executive’s employment by the Company or by an affiliate of the Company continues on such date; and
 
  -   New Options for 105,000 shares (some of which are ISOs and some of which are non-statutory stock options, as provided above) shall vest and become exercisable on each of September 10, 2010, December 10, 2010, March 10, 2011 and June 10, 2011 (for an aggregate 420,000 options during such period) at the Execution Strike Price plus $2.00, if Executive’s employment by the Company or by an affiliate of the Company continues on such date; and
 
  -   New Options for 55,000 shares (some of which are ISOs and some of which are non-statutory stock options, as provided above) shall vest and become exercisable on each of

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      September 10, 2011, December 10, 2011, March 10, 2012 and June 10, 2012 (for an aggregate 220,000 options during such period) at the Execution Strike Price plus $3.00, if Executive’s employment by the Company or by an affiliate of the Company continues on such date; and
 
  -   New Options for 55,000 shares (some of which are ISOs and some of which are non-statutory stock options, as provided above) shall vest and become exercisable on each of September 10, 2012, December 10, 2012, March 10, 2013 and June 10, 2013 (for an aggregate 220,000 options during such period) at the Execution Strike Price plus $4.00, if Executive’s employment by the Company or by an affiliate of the Company continues on such date.
          (e) The New Options that are non-statutory stock options are transferable by Executive to members of his immediate family or to a trust for the benefit of Executive and/or member(s) of his immediate family and/or to a partnership, limited liability company, and/or other entity owned by Executive and/or by member(s) of his immediate family.
          (f) The New Options shall allow Executive the ability (and provide for the cooperation of the Company), if Executive so chooses, among other things: (A) to pay the exercise price for the options via a same-day-sale exercise arrangement and/or (B) to surrender shares (either previously outstanding shares or shares being purchased by exercise of options) to the Company at fair market value for payment of the minimum amount required to satisfy all withholding requirements, and/or (C) to pay all or a part of the exercise price by surrender to the Company, at fair market value, of shares of the Company’s common stock that shall then have been owned for at least six months (or such shorter period as is permissible under applicable law) by Executive and/or by a trust, partnership, limited liability company, or other entity for the benefit of, or owned by, Executive and/or member(s) of his immediate family.
          (g) The shares of Common Stock issuable upon the exercise of the New Options shall be fully vested in the hands of Executive immediately upon such exercise.
     The obligations of the Company in this Section 6 are subject to compliance with applicable law and regulation. Each of the Company and Executive (in the case of the Executive, as requested by the Company and with the Company bearing any associated expense) shall use diligent best efforts at all times to achieve such compliance on a timely basis in accordance with the provisions of this Agreement.
     7.  Restricted Shares . No additional restricted shares beyond those issued to Executive under prior agreements shall be issued to Executive pursuant to this Agreement, but the restricted shares provided for in prior agreements between Executive and the Company shall remain outstanding and vested or vesting, as the case may be, in accordance with such prior agreements respectively.
     8.  Registration . The Company shall use its best efforts: (a) to cause the shares of Common Stock issuable upon the exercise of the New Options to be registered and qualified for public resale on a registration statement and re-offer prospectus filed with the U.S. Securities and Exchange Commission under the Securities Act of 1933, as amended (the “Securities Act”), and under any applicable state securities laws, within ninety (90) days after the Transition Date;

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(b) to maintain in effect all such registrations and qualifications, or substantially similar registrations and qualifications, until Executive and any family member(s) and any entity(ies) related to him shall be free of any and all restrictions on any such sales under the Securities Act and any applicable state securities law(s); and (c) if such effectiveness should lapse or be interrupted before that time, to restore the effectiveness thereof as soon as reasonably possible. These registrations and qualifications are in addition to the registrations and qualifications that may be required as to other securities of the Company that are owned by Executive or that may be issuable pursuant to securities or options heretofore granted or issued to him which other registration and qualification obligations are not amended or waived hereby).
     9.  Benefits . During the Employment Period, the Company shall provide or cause to be provided to Executive at least such employee benefits as are provided to other senior officers of the Company. Without limiting the preceding sentence, the benefits provided to Executive shall include at least family medical and dental, disability, and life insurance.
     10.  Vacation . Executive shall be entitled to annual vacations in accordance with the Company’s vacation policies in effect from time to time for executive officers of the Company.
     11.  Termination
          (a) Executive’s employment by the Company shall be “at will.” In other words, either the Company or Executive may terminate Executive’s employment by the Company at the end of any calendar month, with or without Cause or Good Reason (as such terms are defined below), in its or his sole discretion, upon thirty (30) days’ prior written notice of termination. In addition, Executive’s employment by the Company shall be terminated by his death or disability. Termination of Executive’s employment as provided for herein shall terminate the Employment Period.
          (b) For purposes of this Agreement, in the case of a termination of Executive’s employment hereunder by Executive, the term “Good Reason” shall have the meaning set forth for it below; in the case of a termination of Executive’s employment hereunder by the Company, the term “Cause” shall have the meaning set forth for it below; and the other terms set out below in this Section 11 shall have the meanings provided for them respectively:
               (i) “Good Reason” shall mean (i) any material diminution in the Executive’s authority or role as Chairman of the Board, Chairman of the Company’s Science Advisory Board, and Chief Scientific Officer of the Company; (ii) failure of the Company to pay to the Executive any amounts of base salary and/or incentive cash compensation as provided for in Sections 4 or 5 above, or to honor promptly any of its obligations or commitments regarding stock options or other benefits referred to in Sections 2(b), 6, 7, 8, 9, 10, 14 and/or 16 hereof, or to honor promptly any of its other material obligations hereunder, or under any prior agreement with Executive, to the extent such agreement remains in force; or (iii) a demotion in the Executive’s title (other than the relinquishment of the title “Chief Executive Officer”) or status, provided that , that the Executive must notify the Company of the existence of a Good Reason within 90 days of the initial event giving rise to such Good Reason, and the Company shall have 30 days from the date of such notice to cure such condition and thereby eliminate the Good Reason.

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               (ii) “Cause” shall mean: (A) Executive’s willful and repeated failure reasonably to perform his duties hereunder or to comply with any reasonable and proper direction given by the Board if such failure of performance or compliance is not cured within thirty (30) days following receipt by Executive of written notice from the Company containing a description of such failures and non-compliance and a demand for immediate cure thereof; (B) Executive being found guilty in a criminal court of an offense involving moral turpitude; (C) Executive’s commission of any material act of fraud or theft against the Company; or (D) Executive’s material violation of any of the material terms, covenants, representations or warranties contained in this Agreement if such violation is not cured within thirty (30) days following receipt by Executive of written notice from the Company containing a description of the violation and a demand for immediate cure thereof.
          (c) “Disability” shall mean that the Executive is unable to engage in any substantial gainful activity by reason of any medically determinable physical or mental impairment that can be expected to result in death or can be expected to last for a continuous period of not less than twelve (12) months.
          (d) “Termination Date” shall mean (A) if Executive’s employment is terminated on account of death, the

 
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