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FOURTH AMENDMENT TO EMPLOYMENT AGREEMENT

Employment Agreement Amendment

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Cortex Pharmaceuticals, Inc

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Title: FOURTH AMENDMENT TO EMPLOYMENT AGREEMENT
Date: 7/17/2008
Industry: Biotechnology and Drugs     Sector: Healthcare

FOURTH AMENDMENT TO EMPLOYMENT AGREEMENT, Parties: cortex pharmaceuticals  inc
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EXHIBIT 10.109

FOURTH AMENDMENT TO EMPLOYMENT AGREEMENT

This Fourth Amendment to Employment Agreement (the “Amendment”) is entered into as of July 11, 2008, to be effective August 13, 2008 (the “Effective Date”), between Roger G. Stoll, Ph.D. (the “Executive”) and Cortex Pharmaceuticals, Inc. (the “Company”).

RECITALS

On October 29, 2002, the Company and the Executive entered into an Employment Agreement, which the parties subsequently amended on April 8, 2003, November 10, 2004 and August 13, 2005 (as amended, the “Agreement”).

The Executive served as the Company’s President and Chief Executive Officer pursuant to the terms of the Agreement, and the parties wish to amend the Agreement pursuant to the terms and conditions set forth below.

AGREEMENT

NOW THEREFORE, in consideration of the foregoing and the mutual agreements contained herein, the parties hereby agree as follows effective as of the Effective Date. Except as otherwise defined herein, capitalized terms shall have the meanings assigned to them in the Agreement.

1. The first sentence of Section 1 of the Agreement shall be amended in its entirety to read as follows:

Engagement . During the term of this Agreement, the Company hereby employs the Executive as its Executive Chairman, reporting to the Company’s Board of Directors, and the Executive hereby accepts such employment, on the terms and conditions hereinafter set forth.”

2. Section 2 of the Agreement shall be amended in its entirety to read as follows:

Term . The term of this Agreement shall expire on August 13, 2009.”

3. Section 3 of the Agreement shall be amended in its entirety to read as follows:

Duties . During the term of this Agreement, the Executive shall serve as the Company’s Executive Chairman, and shall have such duties and responsibilities as are set forth in the Company’s Bylaws and such other executive responsibilities as may be assigned to him from time to time by the Board of Directors. In particular and without limitation, the Executive’s duties shall include using diligent efforts as appropriate to (i) assist in raising additional equity capital and research and development funds for the Company, (ii) act as the Chair of the Company’s Executive Committee meetings, (iii) be responsible for stockholder relations and maintain relationships with analysts and fund managers, (iv) develop relationships with potential corporate partners for the licensing, development and commercialization of the Company’s

 


technologies, and (v) lead any merger and acquisition activities involving the Company. The Executive shall use his best efforts and shall act in good faith in performing all duties reasonably required to be performed by him under this Agreement.”

4. The first two sentences of Section 5(e) of the Agreement shall be amended in their entirety to read as follows:

“(e) To allow the Executive to have five (5) days of paid time off each month during the term of this Agreement. The Company and the Executive agree that time devoted by the Executive toward travel to, and attendance at, scientific meetings, boards of director meetings, and trips to meet with business leaders at trade associations shall not constitute paid time off.”

5. Section 8(b) of the Agreement shall be amended in its entirety to read as follows:

“(b) The Executive may terminate his employment under this Agreement at any time for “Good Reason” (as hereinafter defined) upon notice to the Company as described in Section 9(b). As used herein, the term “Good Reason” shall mean only (i) the Company’s breach of any of the material terms of this Agreement, (ii) a material reduction in the Executive’s title or a material reduction or alteration of the duties of the Executive,


 
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