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ECONOMIC DEVELOPMENT AGREEMENT

Development Agreement

ECONOMIC DEVELOPMENT AGREEMENT | Document Parties: LEXICON GENETICS INC/TX You are currently viewing:
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LEXICON GENETICS INC/TX

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Title: ECONOMIC DEVELOPMENT AGREEMENT
Governing Law: Texas     Date: 11/1/2005
Industry: Biotechnology and Drugs     Sector: Healthcare

ECONOMIC DEVELOPMENT AGREEMENT, Parties: lexicon genetics inc/tx
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<PAGE>

 

                                                                    EXHIBIT 10.1

 

                         ECONOMIC DEVELOPMENT AGREEMENT

 

                                     BETWEEN

 

                               THE STATE OF TEXAS

 

                                        AND

 

                         THE TEXAS A&M UNIVERSITY SYSTEM

 

                                       AND

 

                          LEXICON GENETICS INCORPORATED

 

                                  JULY 15, 2005

 

THIS AGREEMENT ("Agreement") is by and among the State of Texas (the "State"),

acting by and through the Office of Economic Development and Tourism, a division

within the Office of the Governor ("OOGEDT"), Texas A&M University System

("TAMUS") and Lexicon Genetics Incorporated ("Lexicon"). The State, TAMUS, and

Lexicon are hereinafter referred to either individually as the "party," or

collectively as the "parties." The Effective Date of this Agreement is July 15,

2005.

 

                                    RECITALS

 

WHEREAS, Texas' low taxes, budgetary discipline, reasonable regulations and

educated workforce continue to make the state a top location for businesses

looking to expand or relocate; and

 

WHEREAS, the State desires to become a world leader in genomics and

biotechnology; and

 

WHEREAS, TAMUS and Lexicon are known for research and development expertise and

Lexicon is particularly known for its gene knockout technology and expertise;

and

 

WHEREAS, gene knockout technology provides a means to systematically identify

the physiological functions of genes, offering the promise of discovering new

and more-effective ways to prevent and treat human and veterinary disease; and

 

WHEREAS, Lexicon employs more than 600 people in the State and had annual

revenues in 2004 of approximately $62 million; and

 

WHEREAS, TAMUS is a Texas public institution of higher education; and

 

WHEREAS, TAMUS and Lexicon have proposed a unique public-private collaboration

for human and veterinary medical research that would be endowed with two (2)

complete copies of a library consisting of three hundred fifty thousand

(350,000) knockout mouse embryonic stem cell clones (the "OmniBank II Library")

housed at two facilities, one being located in Houston and one being located in

College Station; and

 

<PAGE>

 

WHEREAS, TAMUS and Lexicon have proposed that such collaboration be implemented

through the Texas Institute for Genomic Medicine ("TIGM"), a Texas non-profit

corporation formed for such purpose; and

 

WHEREAS, it is in the State's interest to expand and improve the research and

development capability of its public institutions of higher education, including

by facilitating the concentration of expertise in particular areas of scientific

research to enable the development of a platform for recruiting additional

researchers and to obtain related funding from other sources; and

 

WHEREAS, the new facilities and programs related to TIGM are estimated to create

at least 5,000 new full-time jobs for Texans, with an ultimate average annual

payroll of more than $450 million; and

 

WHEREAS, Article III, Section 52-A of the Texas Constitution expressly

authorizes the State to use public funds for the public purposes of development

and diversification of the economy of the State, the elimination of unemployment

or underemployment in the State, or the development of commerce in the State;

and

 

WHEREAS, SB 1771 of the 78th Texas Legislature established the Texas Enterprise

Fund ("TEF") to be used with the express written approval of the Governor,

Lieutenant Governor, and Speaker of the House of Representatives for economic

development, infrastructure development, community development, job training

programs, and business incentives, and HB 7 of the 78th Texas Legislature

appropriated $295 million from the Texas Economic Stabilization Fund to the TEF

for the 2004-2005 biennium; and

 

WHEREAS, the State values Lexicon as a distinguished and important corporate

citizen, and wishes to receive a commitment that Lexicon will expand its

presence and payroll in Texas and provide the intellectual property resources to

enable TAMUS and Lexicon to establish TIGM, and Lexicon wishes to provide such

commitment; and

 

WHEREAS, TAMUS is willing to undertake commitments related to constructing and

renovating facilities for TIGM and supporting the operations of TIGM to carry

out its planned research and development activities, as well as to the creation

of new jobs in the State; and

 

WHEREAS, the Governor, Lieutenant Governor, and Speaker have each approved a

grant from the TEF to TAMUS and Lexicon, as evidenced in the letter attached as

Exhibit A hereto; and

 

WHEREAS, to ensure that the benefits the State provides under this Agreement are

utilized in a manner consistent with Article III, Section 52-a of the Texas

Constitution, and other laws, TAMUS and Lexicon have agreed to comply with

certain conditions and deliver certain performance, including achieving

measurable job creation and retention commitments, in exchange for receiving

these benefits; and

 

WHEREAS, the parties desire to have such proposals set forth in a valid, binding

and enforceable agreement; and

 

WHEREAS, the State believes it is in the best public interest to enter into this

Agreement for the reasons set forth above;

 

                                      -2-

 

<PAGE>

 

                                    AGREEMENTS

 

NOW, THEREFORE, in consideration of the mutual promises herein, the parties

agree as follows:

 

1.     STATE OF TEXAS COMMITMENT

 

      a. GRANT OF FUNDS FROM THE TEXAS ENTERPRISE FUND TO TAMUS. The State shall

pay cash from the Texas Enterprise Fund to TAMUS in the amount of Fifteen

Million Dollars ($15,000,000) as soon as practicable following the execution of

this Agreement (but no later than thirty (30) days after the Effective Date

provided that all necessary documents for disbursement of the funds have been

provided to the State as required), of which (i) Ten Million Dollars

($10,000,000) shall be used by TAMUS to build a facility in College Station to

house one copy of the OmniBank II Library and (ii) Five Million Dollars

($5,000,000) shall be used by TAMUS to renovate existing space at the Institute

of Biosciences and Technology ("IBT") at the Health Science Center in Houston to

house the other copy of the OmniBank II Library, in each case in accordance with

this Agreement.

 

      b. GRANT OF FUNDS FROM THE TEXAS ENTERPRISE FUND TO LEXICON. The State

shall pay cash from the Texas Enterprise Fund to Lexicon in the amount of

Thirty-Five Million Dollars ($35,000,000) as soon as practicable following the

execution of this Agreement (but no later than thirty (30) days after the

Effective Date provided that all necessary documents for disbursement of the

funds have been provided to the State as required), including (i) Thirty Million

Dollars ($30,000,000) for the generation and delivery of the OmniBank II Library

and related intellectual property licenses and (ii) Five Million Dollars

($5,000,000) for the acquisition of bioinformatics software and related

intellectual property licenses, in each case in accordance with this Agreement.

 

2.     TAMUS AND LEXICON FUNDING CONDITIONS

 

TAMUS and Lexicon must meet all of the following "Funding Conditions" or will be

subject to liquidated damages and/or repayment in accordance with this

Agreement. The Funding Conditions are as follows:

 

      a. ESTABLISHMENT OF THE TEXAS INSTITUTE FOR GENOMIC MEDICINE. TAMUS and

Lexicon shall establish TIGM, the initial members of which shall be TAMUS

(participating through Texas A&M University and the Texas A&M Health Science

Center) and Lexicon. TAMUS and Lexicon shall provide the State with sufficient

evidence to confirm TIGM's formation.

 

      b. AGREEMENTS BETWEEN LEXICON AND TAMUS. TAMUS and Lexicon have entered

into, and shall perform their obligations under, agreements with respect to the

matters described in attached Exhibit B. TAMUS and Lexicon shall certify in

writing to the State that the Agreements have been entered into and materially

and substantially comply with the terms as set forth in Exhibit B.

 

            It is understood that this Agreement does not grant the State, apart

from TAMUS, any right to acquire intellectual property transferred to or

developed by TIGM.

 

      c. SECURITY. TAMUS shall provide the state with sufficient evidence that

the State has been provided security for its investment by a pledge of the lease

payments and other revenue from TIGM to TAMUS.

 

                                      -3-

 

<PAGE>

 

      d. JOB TARGETS. TAMUS and Lexicon shall be responsible to the State for

creating, in the aggregate, at least Five Thousand ("5,000") new Employment

Positions in Texas by December 31, 2015, and TAMUS shall be responsible to the

State for maintaining such new Employment Positions in Texas from December 31,

2015 to December 31, 2027. Each of TAMUS and Lexicon shall be responsible for

the respective portions of such aggregate commitment set forth below (such

portion representing the party's respective "Job Target") in accordance with the

following schedule:

 

            (1)    94 jobs by December 31, 2006 (TAMUS portion 45; Lexicon

                  portion 49),

 

            (2)    198 jobs by December 31, 2007 (TAMUS portion 73; Lexicon

                  portion 125),

 

            (3)    357 jobs by December 31, 2008 (TAMUS portion 148; Lexicon

                  portion 209),

 

            (4)    581 jobs by December 31, 2009 (TAMUS portion 280; Lexicon

                  portion 301),

 

            (5)    894 jobs by December 31, 2010 (TAMUS portion 492; Lexicon

                  portion 402),

 

            (6)    1,345 jobs by December 31, 2011 (TAMUS portion 832; Lexicon

                  portion 513),

 

            (7)    1,801 jobs by December 31, 2012 (TAMUS portion 1,166; Lexicon

                  portion 635),

 

            (8)    2,562 jobs by December 31, 2013 (TAMUS portion 1,657; Lexicon

                  portion 905),

 

            (9)    3,573 jobs by December 31, 2014 (TAMUS portion 2,345; Lexicon

                  portion 1,228), and

 

            (10)   5,000 jobs by December 31, 2015 (TAMUS portion 3,384; Lexicon

                   portion 1,616).

 

For the purposes of this Agreement, "Employment Positions" shall be defined as

jobs meeting all of the following criteria:

 

            (i)    New full-time or full-time equivalent employment positions in

                  Texas,

 

            (ii)   With an average annual gross compensation (not including

                  benefits) of at least $60,000, which shall be adjusted for

                  inflation but not to exceed 3% per year, such adjustment to

                  occur first for the compensation standard applicable to 2007,

                  and

 

            (iii) Which may include (A) in the case of Lexicon's portion of the

                  commitment, positions with Lexicon and its affiliates in which

                  Lexicon has a 50% or higher ownership interest, and (B) in the

                  case of TAMUS's portion of the commitment, positions with

                  TIGM, positions with TIGM members, positions with employers in

                  the biotechnology or pharmaceutical industries, and other

                  positions for which TIGM or TIGM members are significantly

                  responsible for creating through efforts specifically targeted

                  at attracting or creating biotechnology and pharmaceutical

                  industry-related positions to Texas, in each case without

                  duplication. For clarity, from and after December 31, 2015 (or

                  earlier, if Lexicon has already satisfied its Job Target

                   commitment in full), positions with Lexicon and its affiliates

                  in which Lexicon has a 50% or higher ownership interest shall

                  be included for purposes of TAMUS's commitment to the State to

                  create and maintain new Employment Positions over the

                  remaining term of the contract.

 

            e. ANNUAL COMPLIANCE VERIFICATION. By January 31 of each year during

the term of this Agreement, beginning in January 2007 and continuing every year

thereafter through January 2028, for TAMUS, and January 2016, for Lexicon, each

of TAMUS and Lexicon, as applicable, must deliver to OOGEDT a compliance

verification signed by a duly authorized representative of the reporting party

that shall certify the number of and generally describe the Employment Positions

existing as of December 31 of the year preceding (an "Annual Compliance

Verification"). There will be a total of twenty-two (22) Annual Compliance

Verifications due, covering jobs created and maintained in years 2006 through

2027. TAMUS and/or Lexicon may, at its option, deliver an Annual Compliance

Verification in January 2006 with respect to Surplus

 

                                      -4-

 

<PAGE>

 

Job Credits, if any, attributable to any new Employment Positions created in

2005. All Annual Compliance Verifications shall be in a form reasonably

satisfactory to OOGEDT and shall provide appropriate back-up data for the

Employment Position numbers provided.

 

3.     LIQUIDATED DAMAGES

 

      a. JOB TARGET. As set forth in Section 2.d above, annually during the term

of this Agreement, through January 2028, TAMUS and, through January 2015,

Lexicon must deliver to OOGEDT an Annual Compliance Verification demonstrating

that their respective Job Targets have been met for the year just ended. The

consequences to TAMUS or Lexicon of satisfying, failing to satisfy or exceeding

its respective Job Target are as follows:

 

            i. COMPLIANCE WITH JOB TARGET. If an Annual Compliance Verification

demonstrates that the applicable party's Job Target has been met for the year

just ended, then such party will be deemed to have met its obligations for such

preceding year and no damages shall be due.

 

            ii. FAILURE TO MEET JOB TARGET. If an Annual Compliance Verification

that demonstrates that such party's Job Target has not been met for the year

just ended, then OOGEDT may require the responsible party to pay liquidated

damages in the amount of Two Thousand Four Hundred Fifteen Dollars ($2,415) per

job for every Employment Position by which it is short that year. It is

understood that as a state agency, TAMUS may not, and does not, guarantee the

obligations of Lexicon. Nor does Lexicon guarantee the obligations of TAMUS.

Neither party shall have any obligation for any shortfalls in the Job Target

obligations of the other party, and each party shall be responsible solely for

its own payment obligations to the State.

 

            iii. EXCEEDING JOB TARGET. If an Annual Compliance Verification

demonstrates that such party's Job Target has been exceeded for the year just

ended, such party will be deemed to have exceeded its Job Target obligations and

will receive a "Surplus Job Credit" for each extra Employment Position generated

and maintained above its Job Target for that year. For purposes of the

foregoing, all Employment Positions created in 2005 will be considered Surplus

Job Credits. TAMUS and Lexicon may utilize their respective earned Surplus Job

Credits in any following year as follows:

 

                   A. such party may expend a Surplus Job Credit in lieu of

            paying liquidated damages in the amount of $2,415 per job (for

            example, if a party owes liquidated damages in the amount of

            $241,500 for 100 Employment Positions lacking in a particular year,

            it may discharge this amount by expending 100 Surplus Job Credits it

            has earned in prior years); or

 

                  B. such party may apply their respective Surplus Job Credits

            toward meeting their remaining Job Target for future years, such

            that if TAMUS and Lexicon accumulate enough Surplus Job Credits they

            will be deemed to have fulfilled all of its obligations under the

            Agreement, and will be released from the Agreement early (for

            example, if TAMUS and Lexicon accumulated at least 5,000 unused

            Surplus Job Credits by December 31, 2026, then TAMUS may apply these

            Surplus Job Credits forward to fulfill its Job Target for 2027, and

            may thereby fulfill its obligations and be released from the

            Agreement one year early).

 

                                      -5-

 

<PAGE>

 

      b. OFFSETS FOR EXTERNAL FUNDING. One of the State's primary objectives

under this Agreement is to support the development of TIGM as a national center

of excellence in genomic medicine, which will require TIGM to successfully

compete for available funding from sources other than the State. Generating such

funding directly benefits the State. In light of these benefits, and without

affecting TAMUS and Lexicon's expectation and intention of satisfying their

respective Job Target commitments set forth in Section 2.d. above, TAMUS and

Lexicon will be entitled to an offset against liabilities, if any, that they may

incur for liquidated damages under Section 3.a. above, calculated as set forth

below, on account of funds received by TIGM and, to the extent related to

research using materials obtained from TIGM, by TIGM members directly or

indirectly from funding sources other than the State, including, without

limitation, all such funds received under grants and contracts from the National

Institutes of Health, other federal government agencies, research institutes,

foundations, and companies in the biotechnology and pharmaceutical industries.

 

The parties will collectively be entitled to an offset equivalent to the

liquidated damages liability associated with the creation or maintenance of

5,000 jobs for one year for each $25 million of such funding. A maximum of $300

million of such external funding may be applied. The offset shall be allocated

between Lexicon and TAMUS as follows:

 

            i. One-half of such offset (e.g., for each $25 million in such

   funding, an amount equivalent to the liquidated damages liability associated

   with the creation or maintenance of 2,500 jobs for one year) will be applied

   to reduce the amount of TAMUS's potential liquidated damages liability for

   shortfalls in achieving or maintaining its portion of the Job Target

   commitment.

 

            ii. The other one-half of such offset will be applied to reduce the

   amount of Lexicon's potential liquidated damages liability for shortfalls in

   achieving or maintaining its portion of the Job Target commitment.

 

Lexicon and TAMUS will be entitled to proportional credit for funding amounts

less than those set forth above. In any event, TAMUS agrees to be responsible

for 5,000 jobs by December 31, 2016, and


 
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