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VYTERIS HOLDINGS (NEVADA), INC. 10% CONVERTIBLE PROMISSORY NOTE

Convertible Promissory Note

VYTERIS HOLDINGS (NEVADA), INC.

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VYTERIS HOLDINGS (NEVADA), INC

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Title: VYTERIS HOLDINGS (NEVADA), INC. 10% CONVERTIBLE PROMISSORY NOTE
Governing Law: New York     Date: 11/13/2006

VYTERIS HOLDINGS (NEVADA), INC.

10% CONVERTIBLE PROMISSORY NOTE, Parties: vyteris holdings (nevada)  inc
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EXHIBIT 10.122

THE SECURITIES REPRESENTED HEREBY HAVE BEEN ISSUED WITHOUT

REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR UNDER

ANY STATE SECURITIES LAWS, AND MAY NOT BE SOLD, TRANSFERRED OR PLEDGED

IN THE ABSENCE OF AN EFFECTIVE REGISTRATION STATEMENT UNDER APPLICABLE

FEDERAL AND STATE SECURITIES LAWS OR AN OPINION OF COUNSEL REASONABLY

SATISFACTORY TO THE COMPANY THAT THE TRANSFER IS EXEMPT FROM

REGISTRATION UNDER APPLICABLE FEDERAL AND STATE SECURITIES LAWS.

VYTERIS HOLDINGS (NEVADA), INC.

10% CONVERTIBLE PROMISSORY NOTE

$1,166,550 Fair Lawn, New Jersey

August 30, 2006

FOR VALUE RECEIVED, the undersigned, Vyteris Holdings (Nevada), Inc.,

a Nevada corporation (the "Issuer"), hereby unconditionally promises to pay, in

accordance with the Note Purchase Agreement (the "Note Purchase Agreement"),

dated as of the date hereof, by and between the Issuer and Spencer Trask

Specialty Group, LLC, a Delaware limited liability company (the "Purchaser"), on

the Maturity Date (as defined in the Note Purchase Agreement) to the order of

the Purchaser, at the office of the Purchaser located at 535 Madison Avenue, New

York, NY or such other address designated by the Purchaser, in lawful money of

the United States of America and in immediately available funds, the principal

amount of One


 
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