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SECURED CONVERTIBLE NOTE

Convertible Promissory Note

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This Convertible Promissory Note involves

GTC BIOTHERAPEUTICS, INC

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Title: SECURED CONVERTIBLE NOTE
Governing Law: Massachusetts     Date: 6/19/2009
Industry: Biotechnology and Drugs     Sector: Healthcare

SECURED CONVERTIBLE NOTE, Parties: gtc biotherapeutics  inc
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Exhibit 2.1

THIS NOTE AND THE SHARES OF CAPITAL STOCK ISSUED UPON ANY CONVERSION HEREOF HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), OR ANY APPLICABLE STATE SECURITIES LAWS AND MAY NOT BE SOLD OR OTHERWISE TRANSFERRED BY ANY PERSON, INCLUDING A PLEDGEE, UNLESS (1) EITHER (A) A REGISTRATION WITH RESPECT THERETO SHALL BE EFFECTIVE UNDER THE SECURITIES ACT, OR (B) THE COMPANY SHALL HAVE RECEIVED AN OPINION OF COUNSEL SATISFACTORY TO THE COMPANY THAT AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT IS AVAILABLE, AND (2) THERE SHALL HAVE BEEN COMPLIANCE WITH ALL APPLICABLE STATE SECURITIES OR “BLUE SKY” LAWS.

SECURED CONVERTIBLE NOTE

 

US$4,512,268

 

June 18, 2009

Subject to the terms and conditions of this Note, for good and valuable consideration received, GTC BIOTHERAPEUTICS, INC., a Massachusetts corporation (the “ Company ”), promises to pay to LFB BIOTECHNOLOGIES, a société par actions simplifiée established under the laws of France (the “ Holder ”), the principal amount of four million five hundred twelve thousand two hundred sixty-eight dollars (US$4,512,268), plus interest which shall accrue at the rate of ten and eight tenths percent (10.8%) per annum on the unpaid principal from the date of this Note until January 1, 2012 (the “Maturity Date”) or until the full amount of principal and accrued interest under this Note is earlier paid, or until the full amount of principal is converted, under the terms hereof. The Company hereby acknowledges that a portion of this note in the principal amount of $512,268 represents a portion of the Company’s share of common program expenses for 2008 under that certain Amended and Restated Joint Development and Commercialization Agreement dated June 30, 2008, and has been funded to the Company prior to the date hereof. The following is a statement of the rights of the Holder and the terms and conditions to which this Note is subject, and to which the Holder hereof, by the acceptance of this Note, agrees:

1. Payment

1.1. Principal & Interest . Interest on the unpaid principal balance of this Note, from the date hereof through and including the dates of payment, shall accrue at a fixed interest rate of ten and eighty hundredths (10.8%) per annum. The Company shall pay to the Holder, in lawful money of the United States, in accordance with the amortization scheduled attached hereto as Annex I , as follows: an installment of principal and interest in the amount of $203,783.20, on October 1, 2009, to be followed by twenty-six (26) consecutive monthly installments of principal and interest commencing November 1, 2009 and continuing on the first day of each month thereafter through and including December 1, 2011, in the amount of $61,646.76, together with a final installment in the amount of any and all remaining outstanding principal and interest (i.e. $3,907,421.28), and all other amounts outstanding, on January 1, 2012. If at any time the principal balance of this Note shall be paid in full pursuant to the terms hereof, then all accrued interest shall be payable at the time of such principal payment. Notwithstanding anything herein to the contrary, if the principal balance of this Note shall be converted pursuant to Section 2 below on or before the Shareholder Approval Deadline (as defined in that certain


Securities Purchase Agreement dated as of the date hereof by and between the Company and the Holder (as may hereafter be amended, restated, supplemented or modified from time to time, the “ Purchase Agreement ”)), no interest shall be payable hereunder.

1.2. Payment . All payments of principal and interest under this Note will be made by wire transfer of immediately available funds in accordance with the wire transfer instructions of Holder provided to the Company.

1.3. Prepayment. This Note may not be prepaid without the written consent of the Holder.

2. Automatic Conversion . Following receipt Shareholder Approval (as defined in the Purchase Agreement) on or before the Shareholder Approval Deadline, on the First Closing Date (as defined in the Purchase Agreement), the principal amount of this Note will automatically convert in accordance with this Section 2 into shares of Series E-1 10% Convertible Preferred Stock of the Company, par value $0.01 per share (“ Series E-1 Preferred Stock ”), as follows:

2.1. Conversion Price . On the First Closing Date, the outstanding principal balance of this Note will be automatically converted, in whole, into fully paid and non-assessable shares of the Company’s Series E-1 Preferred Stock, at a conversion price per share equal to the quotient obtained by dividing (i) the outstanding principal balance of this Note by (ii) $1,000.00, subject to adjustment as set forth herein (the “ Conversion Price ”).

2.2. Mechanics of Conversion . On the First Closing Date this Note shall be deemed to have been converted and a certificate or certificates for shares of Series E-1 Preferred Stock shall be deemed to have been issued, and the Holder or any other person so designated to be named therein shall be deemed to have become a holder of record of such shares for all purposes as of the First Closing Date. Upon such conversion of this Note in full, this Note shall no longer be deemed to be outstanding and all rights with respect to this Note shall immediately cease and terminate on such conversion date, except only the right of the Holder to receive the shares of Series E-1 Preferred Stock to which it is entitled as a result of the conversion.

2.3. Fractional Shares . No fractional shares of Series E-1 Preferred Stock shall be issued upon conversion of this Note. In lieu of any fractional shares to which the Holder would otherwise be entitled, the total number of shares issuable upon conversion shall be rounded up to the nearest whole number, with such portion of the Series E-1 Purchase Amount (as defined in the Purchase Agreement) as shall be necessary to effect the purchase of such whole share to be deemed to have been applied to such purchase.

2.4. Subdivision or Combination of Series E-1 Preferred Stock . If the Company at any time subdivides (by any stock split, stock dividend, recapitalization or otherwise) its outstanding share


 
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