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EX-4.3 FORM OF GLOBAL 5.25% CONVERTIBLE SENIOR NOTE DUE 2025

Convertible Promissory Note

EX-4.3 FORM OF GLOBAL 5.25% CONVERTIBLE SENIOR NOTE DUE 2025 | Document Parties: Antigenics Inc | HSBC BANK USA, NATIONAL ASSOCIATION You are currently viewing:
This Convertible Promissory Note involves

Antigenics Inc | HSBC BANK USA, NATIONAL ASSOCIATION

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Title: EX-4.3 FORM OF GLOBAL 5.25% CONVERTIBLE SENIOR NOTE DUE 2025
Date: 5/24/2005
Industry: Biotechnology and Drugs     Sector: Healthcare

EX-4.3 FORM OF GLOBAL 5.25% CONVERTIBLE SENIOR NOTE DUE 2025, Parties: antigenics inc , hsbc bank usa  national association
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Exhibit 4.3

[Face of Security]

ANTIGENICS INC.

Certificate No. _______

[INSERT PRIVATE PLACEMENT LEGEND AND GLOBAL SECURITY LEGEND]

5.25% Convertible Senior Note due 2025

CUSIP No. ____________

Antigenics Inc., a Delaware corporation (the "COMPANY"), for value

received, hereby promises to pay to Cede & Co., or its registered assigns, the

principal sum of _____________________ dollars ($__________) on February 1, 2025

and to pay interest thereon, as provided on the reverse hereof, until the

principal and any unpaid and accrued interest are paid or duly provided for.

Interest Payment Dates: February 1 and August 1, with the first payment to

be made on August 1, 2005.

Record Dates: January 15 and July 15.

The provisions on the back of this certificate are incorporated as if set

forth on the face hereof.

IN WITNESS WHEREOF, Antigenics Inc. has caused this instrument to be duly

signed.

ANTIGENICS INC.

By: _______________________

Name:

Title:

Dated: _____________________

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TRUSTEE'S CERTIFICATE OF AUTHENTICATION

This is one of the Securities referred to in the within-mentioned Indenture.

HSBC BANK USA, NATIONAL ASSOCIATION, as Trustee

By: _____________________________________

Authorized Signatory

Dated: _________________________

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[REVERSE OF SECURITY]

ANTIGENICS INC.

5.25% CONVERTIBLE SENIOR NOTE DUE 2025

1. INTEREST. Antigenics Inc., a Delaware corporation (the "COMPANY"),

promises to pay interest on the principal amount of this Security at the rate

per annum shown above. The Company will pay interest, payable semi-annually in

arrears, on February 1 and August 1 of each year, with the first payment to be

made on August 1, 2005. Interest on the Securities will accrue on the principal

amount from, and including, the most recent date to which interest has been paid

or provided for or, if no interest has been paid or provided for, from, and

including, January 25, 2005, in each case to, but excluding, the next interest

payment date or Maturity Date, as the case may be. Interest will be computed on

the basis of a 360-day year of twelve 30-day months.

2. MATURITY. The Securities will mature on February 1, 2025.

3. METHOD OF PAYMENT. Except as provided in the Indenture (as defined

below), the Company will pay interest on the Securities to the persons who are

Holders of record of Securities at the close of business on the record date set

forth on the face of this Security next preceding the applicable interest

payment date. Holders must surrender Securities to a Paying Agent to collect the

principal amount, Redemption Price, Option Purchase Price or Fundamental Change

Repurchase Price of the Securities, plus, if applicable, accrued and unpaid

interest, if any, payable as herein provided upon Redemption, Purchase at

Holder's Option or Repurchase Upon Fundamental Change, as the case may be. The

Company will pay, in money of the United States that at the time of payment is

legal tender for payment of public and private debts, all amounts due in cash

with respect to the Securities, which amounts shall be paid (A) in the case this

Security is in global form, by wire transfer of immediately available funds to

the account specified by the Holder hereof; or (B) in the case this Security is

held, other than global form, by a Holder who is the record holder of more than

five million dollars ($5,000,000) aggregate principal amount of Securities, by

wire transfer of immediately available funds to the account specified by such

Holder or, if no such account is specified, or if this Security is held, other

than in global form, by a Holder who is the record holder of five million

dollars ($5,000,000) or less in aggregate principal amount of Securities, by

mailing a check to such Holder's address shown in the register of the Registrar.

4. PAYING AGENT, REGISTRAR, CONVERSION AGENT. Initially, HSBC Bank USA,

National Association (the "TRUSTEE"), will act as Paying Agent, Registrar and

Conversion Agent. The Company may change any Paying Agent, Registrar or

Conversion Agent without notice.

5. INDENTURE. The Company issued the Securities under an Indenture

dated as of January 25, 2005 (the "INDENTURE") between the Company and the

Trustee. The terms of the Securities include those stated in the Indenture and

those made part of the Indenture by reference to the Trust Indenture Act of 1939

(15 U.S. Code Sections 77aaa-77bbbb) (the "TIA") as amended and in effect from

time to time. The Securities are subject to all such terms, and Holders are

referred to the Indenture and the TIA for a statement of such terms. The

Securities are general unsecured senior obligations of the Company limited to

$50,000,000 aggregate principal amount

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($60,000,000 if the Initial Purchasers have elected to exercise in full the

Option to purchase up to an additional $10,000,000 aggregate principal amount of

the Securities), except as otherwise provided in the Indenture (except for

Securities issued in substitution for destroyed, mutilated, lost or stolen

Securities). Terms used herein without definition and which are defined in the

Indenture have the meanings assigned to them in the Indenture.

6. OPTIONAL REDEMPTION.

The Company shall have the right, at the Company's option, at any

time, and from time to time, on a Redemption Date on or after February 1, 2012,

to redeem all or any part of the Securities at a price payable in cash equal to

one hundred percent (100%) of the principal amount of the Securities to be

redeemed, plus accrued and unpaid interest, if any, to, but excluding, the

Redemption Date.

Upon surrender to the Paying Agent of a Security subject to

Redemption, such Security shall be paid, to the Holder surrendering such

Security, at the Redemption Price plus accrued and unpaid interest to, but

excluding, the Redemption Date, unless the Redemption Date is an interest

payment date, in which case such accrued and unpaid interest will instead be

paid on such interest payment date to the Holder of record of such Security at

the close of business on the record date for such interest payment. The Company

will make at least fourteen (14) semi-annual interest payments with respect to

the Securities prior to redeeming any Securities under this PARAGRAPH 6.

If the Paying Agent (other than the Company) holds on a Redemption

Date money sufficient to pay the aggregate Redemption Price with respect to all

Securities to be redeemed, plus accrued and unpaid interest, if any, payable as

provided in the Indenture upon Redemption, then (unless there shall be a Default

in the payment of such aggregate Redemption Price or of such accrued and unpaid

interest) on and after such date such Securities shall be deemed to be no longer

outstanding, interest on such Securities shall cease to accrue, and such

Securities shall be deemed paid whether or not such Securities are delivered to

the Paying Agent. Thereafter, all rights of the Holders of such Securities shall

terminate with respect to such Securities, other than the right to receive the

Redemption Price, plus such accrued and unpaid interest, in accordance with the

Indenture.

7. NOTICE OF REDEMPTION. Notice of Redemption will be mailed at least

thirty (30) days but not more than sixty (60) days before the Redemption Date to

each Holder of Securities to be redeemed at its address appearing in the

security register. Securities in denominations larger than $1,000 principal

amount may be redeemed in part but only in integral multiples of $1,000

principal amount.

8. PURCHASE BY THE COMPANY AT THE OPTION OF THE HOLDER. Subject to the

terms and conditions of the Indenture, the Company shall become obligated to

purchase, at the option of the Holder, the Securities held by such Holder on

February 1, 2012, February 1, 2015 and February 1, 2020 (each, an "OPTION

PURCHASE DATE") at an Option Purchase Price, payable in cash, equal to one

hundred percent (100%) of the principal amount of the Securities to be

purchased, plus accrued and unpaid interest, if any, to, but excluding, the

applicable Option Purchase Date, upon delivery of a Purchase Notice containing

the information set forth in the

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Indenture, at any time from 9:00 a.m., New York City time, on the date that is

twenty (20) Business Days prior to the applicable Option Purchase Date until

5:00 p.m., New York City time, on the third (3rd) Business Day immediately

preceding the applicable Option Purchase Date and upon delivery of the

Securities to the Paying Agent by the Holder as set forth in the Indenture.

Holders have the right to withdraw any Purchase Notice by delivering to

the Paying Agent a written notice of withdrawal in accordance with the

provisions of the Indenture.

If the Paying Agent (other than the Company) holds on an Option Purchase

Date money sufficient to pay the aggregate Option Purchase Price with respect to

all Securities to be purchased upon Purchase at Holder's Option, plus accrued

and unpaid interest, if any, payable as provided in the Indenture upon Purchase

at Holder's Option, then (unless there shall be a Default in the payment of such

aggregate Option Purchase Price or of such accrued and unpaid interest) on and

after such date such Securities shall be deemed to be no longer outstanding,

interest on such Securities shall cease to accrue, and such Securities shall be

deemed paid whether or not such Securities are delivered to the Paying Agent.

Thereafter, all rights of the Holders of such Securities shall terminate with

respect to such Securities, other than the right to receive the Option Purchase

Price, plus such accrued and unpaid interest, in accordance with the Indenture.

9. REPURCHASE AT OPTION OF HOLDER UPON A FUNDAMENTAL CHANGE. Subject to

the terms and conditions of the Indenture, in the event of a Fundamental Change,

each Holder of the Securities shall have the right, at the Holder's option, to

require the Company to repurchase such Holder's Securities including any portion

thereof which is $1,000 in principal amount or any integral multiple thereof on

a date selected by the Company (the "FUNDAMENTAL CHANGE REPURCHASE DATE"), which

date is no later than thirty (30) days after the date on which notice of such

Fundamental Change is mailed in accordance with the Indenture, at a price

payable in cash equal to one hundred percent (100%) of the principal amount of

such Security, plus accrued and unpaid interest to, but excluding, the

Fundamental Change Repurchase Date.

Within thirty (30) days after the occurrence of the Fundamental Change,

the Company must mail, or cause to be mailed, notice of the occurrence of such

Fundamental Change to each Holder at the address of such Holder appearing in the

register of the Registrar. Such notice shall include, among other things, a

description of the procedure which a Holder must follow to exercise the

Fundamental Change Repurchase Right. To exercise the Fundamental Change

Repurchase Right, a Holder of Securities must, in accordance with the provisions

of the Indenture, (i) deliver, no later than 5:00 p.m., New York City time, on

the third (3rd) Business Day immediately preceding the Fundamental Change

Repurchase Date, a Purchase Notice to the Company (if it is acting as its own

Paying Agent) or to the Paying Agent; and (ii) deliver, at any time after the

delivery of such Purchase Notice, the Securities with respect to which the

Holder is exercising its Fundamental Change Repurchase Right (together with all

necessary endorsements). If the Securities delivered in connection with a

Holder's exercise of its Fundamental Change Repurchase Right are held in

book-entry form through the Depositary, then such Purchase Notice must comply

with applicable procedures of the Depositary.

10. CONVERSION.

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Subject to earlier Redemption, Purchase at Holder's Option or Repurchase

Upon Fundamental Change, Holders may surrender Securities in integral multiples

of $1,000 principal amount for conversion into shares of Common Stock in

accordance with ARTICLE X of the Indenture at any time prior to stated maturity.

To convert a Security, a Holder must (1) complete and sign the Conversion

Notice, with appropriate signature guarantee, on the back of the Security, (2)

surrender the Security to a Conversion Agent, (3) furnish appropriate

endorsements and transfer documents if required by the Registrar or Conversion

Agent, (4) pay the amount of interest, if any, the Holder must pay in accordance

with the Indenture and (5) pay any tax or duty if required pursuant to the

Indenture. A Holder may convert a portion of a Security if the portion is $1,000

principal amount or an integral multiple of $1,000 principal amount.

The initial Conversion Rate is 92.9023 shares of Common Stock per $1,000

principal amount of Securities (which results in an effective initial Conversion

Price of approximately $10.76 per share) subject to adjustment in the event of

certain circumstances as specified in the Indenture. The Company will deliver a

check in lieu of any fractional share. Except as other otherwise provided herein

or in the Indenture, on conversion, no payment or adjustment for any unpaid and

accrued interest on, or additional interest with respect to, the Securities will

be made. If a Holder surrenders a Security for conversion after the close of

business on the record date for the payment of an installment of interest and

prior to the related interest payment date, such Security, when surrendered for

conversion, must be accompanied by cash payment of an amount equal to the

interest thereon which the registered Holder at the close of business on such

record date is to receive (other than overdue interest, if any, that has accrued

on such Security), unless such Security has been called for Redemption as

described in the Indenture.

The Conversion Rate applicable to each Security that is surrendered for

conversion, in accordance with the Securities and ARTICLE X of the Indenture, at

any time from, and including, the date that is fifteen (15) Business Days prior

to the date originally announced by the Company as the anticipated effective

date of a Make-Whole Fundamental Change until, and including, the date that is

fifteen (15) Business Days after the actual effective date of such Make-Whole

Fundamental Change shall be increased to an amount equal to the Conversion Rate

that would, but for SECTION 10.15 of the Indenture, otherwise apply to such

Security pursuant to ARTICLE X of the Indenture, plus an amount equal to the

Make-Whole Conversion Rate Adjustment; provided, however, that such increase to

the Conversion Rate shall not apply if (i) such Make-Whole Fundamental Change

constitutes a Public Acquirer Fundamental with respect to which the Company

shall have duly made, and given full effect to, an election, pursuant to and in

accordance with SECTION 10.15(F) of the Indenture, to make an Acquirer Stock

Conversion Right Adjustment; or (ii) such Make-Whole Fundamental Change is

announced by the Company but shall not be consummated.

Any shares of Common Stock that are issued upon conversion of a Security

shall bear the Private Placement Legend until after the second anniversary of

the later of the Issue Date and the last date on which the Company or any

Affiliate was the owner of such shares or the Security (or any predecessor

security) from which such shares were converted (or such shorter period of time

as permitted by Rule 144(k) under the Securities Act or any successor provision

thereunder) (or such longer period of time as may be required under the

Securities Act or applicable state

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securities laws, as set forth in an Opinion of Counsel, unless otherwise agreed

by the Company and the Holder thereof).

11. DENOMINATIONS, TRANSFER, EXCHANGE. The Securities are in registered

form, without coupons, in denominations of $1,000 principal amount and integral

multiples of $1,000 principal amount. The transfer of Securities may be

registered and Securities may be exchanged as provided in the Indenture. The

Registrar may require a Holder, among other things, to furnish appropriate

endorsements and transfer documents. No service charge shall be made for any

such registration of transfer or exchange, but the Company may require payment

of a sum sufficient to cover any tax or similar governmental charge that may be

imposed in connection with certain transfers or exchanges. The Company or the

Trustee, as the case may be, shall not be required to register the transfer of

or exchange any Security (i) d


 
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