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SHARE CONTRIBUTION AND EXCHANGE AGREEMENT

Contribution Agreement

SHARE CONTRIBUTION AND
                               EXCHANGE AGREEMENT
 | Document Parties: BIOVEX GROUP, INC. | BIOVEX LIMITED You are currently viewing:
This Contribution Agreement involves

BIOVEX GROUP, INC. | BIOVEX LIMITED

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Title: SHARE CONTRIBUTION AND EXCHANGE AGREEMENT
Date: 6/20/2006

SHARE CONTRIBUTION AND
                               EXCHANGE AGREEMENT
, Parties: biovex group  inc. , biovex limited
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                                                                     EXHIBIT 4.4

                               BIOVEX GROUP, INC.

                                 BIOVEX LIMITED

                                       AND

                        THE SHAREHOLDERS OF BIOVEX LIMITED

                             SHARE CONTRIBUTION AND
                               EXCHANGE AGREEMENT

    for the acquisition of the entire issued share capital of BioVex Limited

                                 August 30, 2005

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THIS AGREEMENT is made as of August 30, 2005

BETWEEN:-

(1)   BIOVEX GROUP, INC., a Delaware corporation (the "NEW PARENT");

(2)   BIOVEX LIMITED, a private company limited by shares incorporated in England
     and Wales (registered number 3480520), whose registered office is at 70
     Milton Park, Abingdon, Oxfordshire, OX14 4RX ("SUBSIDIARY"); and

(3)   THE SHAREHOLDERS OF BIOVEX LIMITED whose names and addresses are set out in
     column 1 of Schedule 1 hereto (each, a "SHAREHOLDER" and together, the
     "SHAREHOLDERS").

WHEREAS:

(A)   The Shareholders together are the legal and beneficial owners of 100% of
     the issued share capital in the Subsidiary (the "SUBSIDIARY SHARES") as is
     detailed in column 2 of Schedule 1 hereto; and

(B)   Each of the Shareholders has agreed to sell and the New Parent has agreed
     to purchase the Subsidiary Shares on the terms and conditions set out in
     this Agreement (the "EXCHANGE").

NOW IT IS AGREED as follows:-

1.    SALE AND PURCHASE

1.1   The Shareholders shall sell and the New Parent shall purchase the
     Subsidiary Shares for the consideration specified in clause 2 below.

1.2   The Subsidiary Shares are sold with full title guarantee and free from any
     option, charge, lien, equity, encumbrance, rights of pre-emption or any
     other third party rights and together with all rights attached to them at
     the date of this Agreement or subsequently becoming attached to them.
     Immediately following the sale of the Subsidiary Shares contemplated
     hereby, the outstanding capitalisation of the New Parent will consist
     solely of the Consideration Shares (as defined below), the certificate of
     incorporation of the New Parent will be in the form attached hereto as
      Exhibit A, and each Shareholder shall become a party to a Stockholders'
     Agreement in the form attached hereto as Exhibit B.

2.    CONSIDERATION

     The consideration for the purchase of the Subsidiary Shares shall be
     satisfied on Completion by the issue of such number of shares of Common
     Stock, par value $0.0001 per share; Series A Preferred Stock, par value
     $0.0001 per share; Series B Preferred Stock, par value $0.0001 per share;
     Series C Preferred Stock, par value


                                        2

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     $0.0001 per share; Series D Preferred Stock, par value $0.0001 per share;
     and Series M Preferred Stock, par value $0.0001 per share; as is set out in
     column 3 opposite each Shareholder's respective name in Schedule 1 hereto
     (the "CONSIDERATION SHARES").

     Such Consideration Shares shall be issued in respect of the number of
     Ordinary Shares, 'A' Ordinary Shares, 'B' Ordinary Shares, 'C' Ordinary
     Shares and 'D' Ordinary Shares, together with the aggregate number of
     Deferred Shares, if any, held by each Shareholder, as indicated in column 2
     of Schedule 1 hereto.

     For the avoidance of doubt, shares of Series M Preferred Stock shall be
     issued to Merlin General Partner Limited ("MERLIN") as the Consideration
     Shares in respect of the Ordinary Shares held by Merlin in order to give
     continuing effect to the liquidation preference Merlin enjoys in respect of
     such Ordinary Shares.

3.    COMPLETION

3.1   Completion shall take place forthwith upon the signing of this Agreement by
     all the parties hereto at the offices of Wilmer Cutler Pickering Hale and
     Dorr LLP, 10 Noble Street, London EC2V 7QJ, England.

3.2   At Completion the Shareholders shall deliver or cause to be delivered to
     the New Parent duly executed transfers of the Subsidiary Shares together
     with the share certificates for them or, where the share certificates have
     been lost or are otherwise unobtainable, an indemnity in a form
      satisfactory to the New Parent.

3.3   Where facsimile copies of this Agreement or duly executed transfers of the
     Subsidiary Shares have been received by the New Parent, the relevant
     Shareholder or Shareholders warrant(s) and represent(s) that the originals
     of such documents have been sent by courier or registered post (or the
     equivalent) to the New Parent c/o Wilmer Cutler Pickering Hale and Dorr
     LLP, 10 Noble Street, London EC2V 7QJ, England, marked for the attention of
     Timothy Corbett.

3.4   Prior to Completion, the directors of Subsidiary shall have resolved to
     approve the transfers of the Subsidiary Shares and (subject to them being
     duly stamped) the registration of the New Parent as member in respect of
     the Subsidiary Shares.

4.    WARRANTIES

4.1   Each of the parties warrants and represents to the other that it has the
     full power and authority to enter into this Agreement and that this
     Agreement has been duly authorised, executed and delivered by it or on its
     behalf.

4.2   Each of the Shareholders severally warrants and represents to the New
     Parent that:

     (a)   he is the owner of the Subsidiary Shares set forth opposite his
          respective name in Schedule 1 hereto and, except for such Subsidiary
          Shares as are identified on Schedule 1 hereto, he does not own any
          shares of Subsidiary or (save for any ordinary shares issuable upon
          the conversion of such Subsidiary Shares


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          that are convertible into ordinary shares) have the right to purchase
          or acquire any shares of Subsidiary through any subscription, warrant,
          option, convertible security or other right (contingent or otherwise)
          (other than pursuant to options granted under the Subsidiary's
          employee share option schemes which are listed on Schedule 2 hereto
          and which will be converted into options to purchase Common Stock of
          the New Parent as described in Section 7 hereof);

     (b)   he will at Completion have the right and power to sell and transfer or
          procure the transfer of all of such Subsidiary Shares to the New
          Parent in accordance with the provisions of this Agreement, free and
          clear of any liens, claims or other encumbrances; and

     (c)   execution and performance of the provisions of this Agreement will
          effect the transfer of good and marketable title to and the full legal
          and beneficial ownership in such Subsidiary Shares, free and clear of
          any liens, claims or other encumbrances.

4.3   Each of the Shareholders waives all restrictions on transfer (including
     pre-emption rights) and any procedural requirements not specifically
     provided for herein which may exist in relation to the sale of the
     Subsidiary Shares contemplated hereby under the articles of association of
     Subsidiary, any subscription or investment agreement relating to Subsidiary
     or otherwise.

4.4   The Subsidiary covenants to the New Parent that the Subsidiary Shares
     constitute the whole of the allotted and issued share capital of
     Subsidiary.

5.    INVESTMENT WARRANTIES

5.1   Each Shareholder severally warrants that he: (i) is an "ACCREDITED
     INVESTOR" within the meaning of Rule 501 of Regulation D of the U.S.
     Securities Act of 1933, as amended (the "SECURITIES ACT"); or (ii) is not a
     "U.S. PERSON" as such term is defined in Regulation S under the Securities
      Act ("REGULATION S"), and is not acquiring the securities for the account
     or benefit of any U.S. Person, and that he is obtaining the Consideration
     Shares in an "OFFSHORE TRANSACTION" (as such term is defined in Regulation
     S under the Securities Act) outside the United States, and that, to his
     knowledge, no "DIRECTED SELLING EFFORTS" (as such term is defined in
     Regulation S) in the United States have been made by the Company in
     connection with his acquisition of Consideration Shares.

5.2   Each Shareholder severally warrants that he is acquiring the Consideration
     Shares for his own account for investment and not with a view to, or for
     sale in connection with, any distribution thereof, nor with any present
     intention of distributing or selling the same; and such Shareholder has no
     present or contemplated agreement, undertaking, arrangement, obligation,
     indebtedness or commitment providing for the disposition thereof.

5.3   Each Shareholder severally warrants that he is familiar with the New Parent
     and Subsidiary, their business and personnel; the officers of the New
     Parent and Subsidiary have made available to such Shareholder any and all
     information which he


                                        4

<PAGE>

     has requested and have answered to such Shareholder's satisfaction all
     inquiries made by such Shareholder with respect to the New Parent and the
     Exchange; and such Shareholder has sufficient knowledge and experience in
      finance and business that he is capable of evaluating the risks and merits
     of his investment in the New Parent and such Shareholder is financially
     able to bear the risks thereof.

5.4   Each Shareholder acknowledges and understands that (i) the Consideration
     Shares have not been registered under the Securities Act and are
     "RESTRICTED SECURITIES" within the meaning of Rule 144 under the Securities
     Act, (ii) the Consideration Shares cannot be sold, transferred or otherwise
     disposed of except in accordance with Regulation S, if applicable, pursuant
     to registration under the Securities Act, or pursuant to an available
     exemption from registration; and hedging transactions involving the
     Consideration Shares may not be conducted unless in compliance with the
     Securities Act; (iii) in any event, the exemption from registration under
     Rule 144 will not be available for at least one year and even then will not
     be available unless a public market then exists for the Common Stock of the
     New Parent, adequate information concerning the New Parent is then
     available to the public, and other terms and conditions of Rule 144 are
     complied with; and (iv) there is now no registration statement on file with
      the U.S. Securities and Exchange Commission with respect to any stock of
     the New Parent and the New Parent has no obligation to register the
     Consideration Shares under the Securities Act. Consideration Shares shall
     not be sold or transferred unless either (i) they first shall have been
     registered under the Securities Act, or (ii) they shall be sold pursuant to
     a valid exemption from the registration requirements of the Securities Act.

5.5   All certificates representing Consideration Shares shall have affixed
     thereto legends in substantially the following form, in addition to any
     other legends that may be required under U.S. federal or state securities
     laws:

          "The Shares represented by this certificate have not been registered
          under the Securities Act of 1933, as amended, and may not be sold,
          transferred or otherwise disposed of except in accordance with the
          provisions of Regulation S under the Securities Act, pursuant to
           registration under the Securities Act, or pursuant to an available
          exemption from registration, and hedging transactions involving the
          Shares represented by this Certificate may not be conducted unless in
          compliance with the Securities Act."

6.    TERMINATION OF SUBSIDIARY SHAREHOLDER AGREEMENTS

     Each party agrees that each of: (i) the investment agreement dated 3
     October 2003 between Subsidiary and certain shareholders of Subsidiary
     (except for article 6 (Warranties and Indemnity) thereof); (ii) the
     subscription agreement dated 21 December 2004 between Subsidiary and
     certain shareholders of Subsidiary (except for article 5 (Warranties)
     thereof); (iii) the subscription agreement dated 26 May 2005 between
     Subsidiary and certain shareholders of Subsidiary (except for article 3
     (Warranties) thereof); and (iv) the Management Rights Letter dated 3
     October 2003 between Subsidiary and Merlin General Partner II Limited shall
     terminate in its


                                       5

<PAGE>

     entirety upon the signing of this Agreement, and each party irrevocably
     waives all rights and claims under each such agreement with effect from
     Completion, except for claims in respect of warranties as provided in each
     of the subscription agreements set forth above, upon and pursuant to the
     terms of the surviving articles thereof.

7.    SUBSIDIARY OPTIONS

7.1   As soon as reasonably practicable following Completion, the New Parent will
     extend an offer to each person identified on Schedule 2 hereto (each, an
     "OPTIONHOLDER") to exchange the option or options to purchase the number of
     Ordinary Shares in the Subsidiary set forth opposite such Optionholder's
      name on Schedule 2 hereto for an option or options to acquire an equal
     number of shares of Common Stock of the New Parent upon substantially
     equivalent terms (excluding terms which relate to the tax status of such
     options).

7.2   As soon as reasonably practicable following Completion, the New Parent, in
     its capacity as a shareholder of the Subsidiary, will amend the Articles of
     Association of the Subsidiary to provide that, immediately following any
     issue of Ordinary Shares of the Subsidiary (pursuant to the exercise of any
     employee option to purchase such shares) thereafter, the holder thereof
     will by virtue of such articles be obliged to transfer such Ordinary Shares
     of the Subsidiary to the New Parent in consideration for the issuance by
     the New Parent of an equal number of shares of Common Stock of the New
     Parent.

8.    MISCELLANEOUS

8.1   Each of the Shareholders confirms that he has no and will have no claims
     (whether statutory, contractual or otherwise) against the New Parent or
     Subsidiary or any of their subsidiaries (if any) for compensation, damages
     or otherwise in relation to the Subsidiary Shares, the Consideration
     Shares, any other ownership interest in the Subsidiary or the New Parent or
     this Agreement, and hereby waives any such claims that he may have.

8.2   In relation to its subject matter this Agreement represents the entire
     understanding and constitutes the whole agreement, and supersedes any
     previous agreement, between the parties and, save as provided in this
     Agreement, no party has relied on any representation made by any other
     party.

8.3   The Shareholders shall after completion execute all such deeds and
     documents and do all such things as the New Parent may reasonably require
     for perfecting the transactions intended to be effected under or pursuant
     to this Agreement and for vesting in the New Parent the full benefit of the
     Subsidiary Shares.

8.4   This Agreement may be executed in more than one counterpart (including
     facsimile copies), each of which shall be deemed to constitute an original,
     and shall become effective when one or more counterparts have been signed
     by all of the parties hereto and such a counterpart (so signed) has been
     delivered to each of the parties hereto.


                                       6

<PAGE>

8.5   This Agreement shall be governed by, and construed in accordance with, the
     laws of England and Wales and the parties hereby submit to the
     non-exclusive jurisdiction of the English courts.

8.6   The New Parent shall be liable for any stamp duty or stamp duty reserve tax
     arising as a result of this Agreement.

8.7   This Agreement may be amended, modified or supplemented and portions of it
     waived in writing by the New Parent, the Subsidiary and Shareholders
     holding not les


 
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