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Exhibit 10.53compensation Agreement

Consulting Services Agreement

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 This Consulting Services Agreement involves

Dermisonics, Inc | Ruffa Ruffa, P.C.

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Date: 5/25/2005

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                             COMPENSATION AGREEMENT


     This Compensation Agreement is dated May 3, 2005 between Dermisonics, Inc.,

a Nevada corporation (the "Company"), and Ruffa & Ruffa, P.C. ("Consultants").


     WHEREAS, the Consultants have rendered legal services in favor of the

Company since March 2004; and


     WHEREAS, the value of the legal services rendered by the Consultants as of

April 30, 2005 was $177,037.75 ("Amount Due"); and


     WHEREAS, the Company wishes to compensate the Consultants by issuing to

them shares of its common stock for such services rendered and the Consultants

are willing to accept shares of common stock in full payment for the services



     NOW THEREFORE, in consideration