GED CONFIDENTIALITY AGREEMENT

                                                                   EXHIBIT 10.13

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                            CONFIDENTIALITY AGREEMENT

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This Agreement is made by and between MacroChem Corporation, having a place of

business at 110 Hartwell Avenue, Lexington, Massachusetts 02421 (the "Company"),

and Glenn Deegan, 27 Allerton Road, Milton, MA 02186, (the "Employee").

In consideration of the Employee's employment or continued employment by the

Company, the Company and the Employee hereby agree as follows:

It is agreed that the Employee will promptly disclose and assign to the Company

all inventions made by the Employee while in its employment, which shall be

within the existing or contemplated scope of the Company's business, together

with such patent or patents as may be obtained thereon, in the United States and

all foreign countries, and will execute all proper papers for use in applying

for, obtaining and maintaining such United States and foreign patents as the

Company may desire, and will e