Re: Collaboration Agreement dated August 1, 2003 between Structural GenomiX, Inc. and OSI Pharmaceuticals, Inc.

Collaboration Agreement

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Title: Re: Collaboration Agreement dated August 1, 2003 between Structural GenomiX, Inc. and OSI Pharmaceuticals, Inc.
Date: 9/2/2005

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EXHIBIT 10.24

OSI Pharmaceuticals, Inc.

58 South Service Road, Suite 110

Melville, NY 11747

T 631.962.2000 F 631.752.3880

www.osip.com

[(OSI)(TM) PHARMACEUTICALS LOGO)]

January 11, 2004

VIA FEDERAL EXPRESS

Sean A. McCarthy, D.Phil.

Vice President, Business Development

Structural GenomiX, Inc.

10505 Roselle Street

San Diego, CA 92121

Re: Collaboration Agreement dated August 1, 2003 between Structural

GenomiX, Inc. and OSI Pharmaceuticals, Inc.

Dear Sean:

This letter confirms acceptance by Structural GenomiX o

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