Collaboration Agreement

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This Collaboration Agreement involves

NEKTAR THERAPEUTICS | Pfizer Inc.

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Title: Collaboration Agreement
Date: 3/14/2005
Industry: HTHEQP Sector: HEALTH

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Amendment to Collaborative Development & License Agreement dated 9/12/95

EXHIBIT 10.53

[ * ] = CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED BY BRACKETS, HAS BEEN OMITTED AND FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION PURSUANT TO RULE 24B-2 OF THE SECURITIES EXCHANGE ACT OF 1934, AS AMENDED.

INHALE

12 September 1995