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Collaboration Agreements

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51) COLLABORATION AGREEMENT

Parties: BRISTOL-MYERS SQUIBB COMPANY | EXELIXIS, INC
Law Firm: Cooley Godward
Document Date: 3/10/2009
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware


52) AMENDMENT TO LICENSE AND COLLABORATION AGREEMENT

Parties: ENZON PHARMACEUTICALS INC
Document Date: 3/9/2009
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:New York


53) LICENSE AND COLLABORATION AGREEMENT

Parties: ENZON PHARMACEUTICALS INC
Law Firm: Wiggin Dana
Document Date: 3/9/2009
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:New York


54) AMENDMENT TO LICENSE AND COLLABORATION AGREEMENT

Parties: ENZON PHARMACEUTICALS INC
Document Date: 3/9/2009
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:New York


55) AMENDMENT TO LICENSE AND COLLABORATION AGREEMENT

Parties: ENZON PHARMACEUTICALS INC
Document Date: 3/9/2009
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:New York


56) RESEARCH AND DEVELOPMENT COLLABORATION AND LICENSE AGREEMENT

Parties: DYNAVAX TECHNOLOGIES CORPORATION | Edinburgh Pharmaceutical Industries Limited | Glaxo Group Limited
Law Firm: Cooley Godward
Document Date: 3/6/2009
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware


57) Vaccine Adjuvant License and Collaboration Agreement

Parties: CELLDEX THERAPEUTICS, INC. | 3M COMPANY | 3M INNOVATIVE PROPERTIES COMPANY
Law Firm: Fox Rothschild
Document Date: 3/5/2009
Industry: Biotechnology and Drugs
Sector: Healthcare


58) RESEARCH COLLABORATION AND COMMERCIALIZATION AGREEMENT

Parties: CELLDEX THERAPEUTICS, INC
Document Date: 3/5/2009
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:New Jersey


59) COST SHARING AGREEMENT MASIMO CORPORATION ? MASIMO INTERNATIONAL HOLDINGS

Parties: Masimo Corporation
Document Date: 3/4/2009
Industry: Medical Equipment and Supplies
Sector: Healthcare


60) RESEARCH COLLABORATION AND LICENSE AGREEMENT

Parties: ALNYLAM PHARMACEUTICALS, INC | BIOMEDICAL RESEARCH, INC
Law Firm: Wilmer Cutler;Dewey Ballantine
Document Date: 3/2/2009
Industry: Biotechnology and Drugs
Sector: Healthcare


61) LICENSE AND COLLABORATION AGREEMENT

Parties: ALNYLAM PHARMACEUTICALS, INC. | F Hoffmann-La Roche Ltd | Hoffmann-La Roche Inc | Alnylam Europe AG
Document Date: 3/2/2009
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware


62) FIRST AMENDMENT TO THE LICENSE AND COLLABORATION AGREEMENT

Parties: VALEANT PHARMACEUTICALS INTERNATIONAL | Glaxo Group Limited
Document Date: 3/2/2009
Industry: Biotechnology and Drugs
Sector: Healthcare


63) PRE-CLINICAL DEVELOPMENT COLLABORATION AGREEMENT

Parties: ISIS PHARMACEUTICALS INC
Document Date: 2/26/2009
Industry: Biotechnology and Drugs
Sector: Healthcare


64) SECOND AMENDMENT TO RESEARCH COLLABORATION AND LICENSE AGREEMENT

Parties: ASTRAZENECA AB | PALATIN TECHNOLOGIES, INC
Document Date: 2/17/2009
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:New York


65) COLLABORATION AND SUPPLY AGREEMENT

Parties: DOR BIOPHARMA INC | Enteron Pharmaceuticals, Inc | SIGMA-TAU Pharmaceuticals, Inc
Document Date: 2/13/2009
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:New York


66) AMENDMENT NO. 3 TO THE COLLABORATION AND LICENSE AGREEMENT

Parties: IMMUNOGEN INC | SANOFI-AVENTIS US LLC
Document Date: 2/6/2009
Industry: Biotechnology and Drugs
Sector: Healthcare


67) COLLABORATION, LICENSE and PURCHASE AGREEMENT

Parties: EXACT SCIENCES CORPORATION | GENZYME CORPORATION
Law Firm: Ropes Gray
Document Date: 1/28/2009
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Massachusetts


68) RESEARCH COLLABORATION AND LICENSE AGREEMENT

Parties: BioDelivery Sciences International, Inc
Document Date: 1/23/2009
Industry: Biotechnology and Drugs
Sector: Healthcare


69) AMENDED AND RESTATED COLLABORATION AND LICENSE AGREEMENT

Parties: NITROMED INC | Archemix Corp
Law Firm: Mintz Levin;Cooley Godward
Document Date: 12/19/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware


70) EXECUTION COPY COLLABORATIVE RESEARCH AND LICENSE AGREEMENT

Parties: NITROMED INC | ARCHEMIX CORP | TAKEDA PHARMACEUTICAL COMPANY LIMITED
Law Firm: Mintz Levin
Document Date: 12/19/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:New York


71) COLLABORATIVE RESEARCH AND LICENSE AGREEMENT

Parties: NITROMED INC | ARCHEMIX CORP
Law Firm: Mintz Levin
Document Date: 12/19/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:New York


72) COLLABORATIVE RESEARCH AND LICENSE AGREEMENT

Parties: NITROMED INC | ARCHEMIX CORP | ELAN PHARMA INTERNATIONAL, LIMITED
Law Firm: Mintz Levin
Document Date: 12/19/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware


73) COLLABORATIVE RESEARCH, SERVICES AND LICENSE AGREEMENT

Parties: NITROMED INC | ARCHEMIX CORP | PFIZER INC
Law Firm: Mintz Levin
Document Date: 12/19/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:New York


74) COLLABORATION AGREEMENT

Parties: DAIICHI SANKYO CO, LTD | SEATTLE GENETICS, INC
Document Date: 11/7/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Washington


75) Re: Amendment No. 3 to Collaboration Agreement

Parties: ADOLOR CORP
Document Date: 10/28/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware


76) FIRST AMENDMENT TO RESEARCH COLLABORATION AND LICENSE AGREEMENT

Parties: ASTRAZENECA AB | PALATIN TECHNOLOGIES, INC
Document Date: 9/29/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:New York


77) FOURTH AMENDMENT to the Collaboration, License and Supply Agreement

Parties: ACUSPHERE INC
Document Date: 9/8/2008
Industry: Biotechnology and Drugs
Sector: Healthcare


78) LICENSE AND COLLABORATION AGREEMENT

Parties: IMMUNOMEDICS, INC
Law Firm: Morgan Lewis
Document Date: 8/29/2008
Industry: Biotechnology and Drugs
Sector: Healthcare


79) EXCLUSIVE RESEARCH COLLABORATION, LICENSE AND COMMERCIALIZATION AGREEMENT

Parties: MERCK & CO, INC | Vertex Pharmaceuticals Incorporated
Document Date: 8/11/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:New York


80) LICENSE AND COLLABORATION AGREEMENT

Parties: Alnylam Pharmaceuticals, Inc | Takeda Pharmaceutical Company Limited
Law Firm: Wilmer Cutler;Morgan Lewis
Document Date: 8/8/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware


81) AMENDMENT No. 1 to Collaboration and License Agreement

Parties: BAYER Healthcare AG | BAYER Pharmaceuticals Corporation | Seattle Genetics, Inc
Document Date: 8/8/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:New York


82) FOURTH AMENDMENT TO THE COLLABORATIVE RESEARCH AND LICENSE AGREEMENT

Parties: NESTEC, Ltd | SENOMYX, INC
Document Date: 8/7/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:California


83) COLLABORATION AND EXCLUSIVE LICENSE AGREEMENT

Parties: 3SBIO INC | AMAG PHARMACEUTICALS, INC
Law Firm: Cooley Godward;Simpson Thacher
Document Date: 8/7/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:New York


84) THIRD AMENDMENT

Parties: ACUSPHERE INC
Document Date: 6/26/2008
Industry: Biotechnology and Drugs
Sector: Healthcare


85) 3D COLLABORATION AGREEMENT

Parties: SanDisk Corporation | Toshiba Corporation
Document Date: 6/17/2008
Industry: Computer Storage Devices
Sector: Technology
Governing Law:California


86) AMENDED AND RESTATED COLLABORATION AND LICENSE AGREEMENT

Parties: ANTISENSE THERAPEUTICS LTD | ANTISENSE THERAPEUTICS, LIMITED | ISIS PHARMACEUTICALS, INC | Teva Pharmaceutical Industries Ltd
Document Date: 5/12/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware


87) Collaboration And License Agreement

Parties: NEUROBIOLOGICAL TECHNOLOGIES INC /CA/
Document Date: 5/12/2008
Industry: Biotechnology and Drugs
Sector: Healthcare


88) Collaboration And License Agreement

Parties: NEUROBIOLOGICAL TECHNOLOGIES INC /CA/
Document Date: 5/12/2008
Industry: Biotechnology and Drugs
Sector: Healthcare


89) AMENDED AND RESTATED COLLABORATION AGREEMENT

Parties: ALIMERA SCIENCES, INC | CONTROL DELIVERY SYSTEMS, INC | PSIVIDA, INC
Law Firm: Ropes Gray
Document Date: 5/12/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:New York


90) COLLABORATION AGREEMENT

Parties: CYBERKINETICS NEUROTECHNOLOGY SYSTEMS, INC. | NEUROMetrix, Inc | PNIR, LLC
Law Firm: Ice Miller
Document Date: 3/31/2008
Governing Law:Massachusetts


91) LICENSE AND COLLABORATION AGREEMENT dated as of December 4, 2007

Parties: ADOLOR CORP | ADOLOR CORPORATION | Pfizer Inc
Law Firm: Morgan Lewis
Document Date: 2/29/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware


92) AMENDED AND RESTATED COLLABORATION AGREEMENT

Parties: BIOMARIN PHARMACEUTICAL INC | BioMarin Pharmaceutical, Inc | Genzyme Corporation | Genzyme, BioMarin and BioMarin/Genzyme LLC
Document Date: 2/28/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware


93) LICENSE AND COLLABORATION AGREEMENT

Parties: AMICUS THERAPEUTICS INC | Shire Pharmaceuticals Ireland Ltd
Law Firm: Wilson Sonsini;Morgan Lewis
Document Date: 2/8/2008
Industry: Biotechnology and Drugs
Sector: Healthcare


94) AMENDMENT NO. 2 TO THE COLLABORATION AND LICENSE AGREEMENT

Parties: IMMUNOGEN INC | ImmunoGen and Aventis Pharmaceuticals, Inc | ImmunoGen, Inc | SANOFI-AVENTIS US, LLC
Document Date: 2/7/2008
Industry: Biotechnology and Drugs
Sector: Healthcare


95) HUMAN GENOME SCIENCES AND AEGERA THERAPEUTICS ANNOUNCE LICENSING AND COLLABORATION AGREEMENT ON NOVEL ANTI-CANCER DRUGS

Parties: HUMAN GENOME SCIENCES INC
Document Date: 12/20/2007
Industry: Biotechnology and Drugs
Sector: Healthcare


96) COLLABORATION AND DEVELOPMENT AGREEMENT

Parties: INTERACTIVE GAMES INC. | China Nuvo Solar Energy, Inc | NUVO CHINA SOLAR ENERGY, INC
Document Date: 12/17/2007
Governing Law:Florida


97) COLLABORATION AND DEVELOPMENT AGREEMENT

Parties: INDEVUS PHARMACEUTICALS INC | ALPEX PHARMA SA | VALERA PHARMACEUTICALS, INC
Document Date: 12/12/2007
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:New York


98) Regeneron Initiates Major Global Collaboration with Sanofi-aventis to Develop and Commercialize Fully-Human Therapeutic Antibodies

Parties: REGENERON PHARMACEUTICALS INC
Document Date: 11/29/2007
Industry: Biotechnology and Drugs
Sector: Healthcare


99) COLLABORATION AGREEMENT

Parties: ARADIGM CORP | AERx® Pulmonary Drug Delivery System | CyDex, Inc
Document Date: 11/14/2007
Industry: Medical Equipment and Supplies
Sector: Healthcare
Governing Law:California


100) LICENSE AND COLLABORATION AGREEMENT

Parties: ISIS PHARMACEUTICALS INC | Alnylam Pharmaceuticals, Inc | Regulus Therapeutics LLC
Document Date: 11/9/2007
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware


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