FIRST AMENDMENT TO SALE AND ASSET PURCHASE AGREEMENT

Asset Purchase Agreement

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Emmes Group Consulting LLC | Eucodis Pharmaceuticals | MDI Oncology, Inc | Medical Discoveries, Inc

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Title: FIRST AMENDMENT TO SALE AND ASSET PURCHASE AGREEMENT
Governing Law: Delaware Date: 10/4/2007
Industry: Biotechnology and Drugs Sector: Healthcare

FIRST AMENDMENT TO SALE AND ASSET PURCHASE AGREEMENT

This Amendment (the “ Amendment ”) is made as of this 30 ^th day of September 2007 to that that certain Sale and Asset Purchase Agreement, dated as of July 6, 2007 (the “ Asset Agreement ”), by and among Medical Discoveries, Inc., a Utah corporation (“ MDI ”), MDI Oncology, Inc., a Delaware corporation and wholly-owned subsidiary of MDI (“ MDI Oncology ”), and Eucodis Pharmaceuticals Forschungs - und Entwicklungs GmbH, an Austrian company (“ Eucodis ”). Capitalized terms used herein but not otherwise defined shall have the meanings ascribed to them in the Asset Agreement.

WHEREAS, the Asset Agreement (including, but not limited to, Sections 3.1 and 4.2 thereof) contemplates that that the transactions thereunder (such transactions, the “ Asset Sale ”) shall close on or before September 30, 2007; and

WHEREAS, the Parties remain committed to closing the Asset Sale, however, desire to extend the period provided for closing the Asset Sale.

NOW, THEREFORE, in consideration of the mutual promises exchanged herein, the Parties agree as follows:

1. Amendment of Asset Agreement .

Section 1.11 of the Asset Agreement is hereby amended and restated in its entirety as to read a

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