AGREEMENT AND PLAN OF MERGER

Agreement and Plan of Merger

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HOLOGIC INC | HYDROGEN ACQUISITION, INC | R2 TECHNOLOGY, INC

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Title: AGREEMENT AND PLAN OF MERGER
Governing Law: Delaware Date: 5/4/2006
Industry: HTHEQP Law Firm: Brown Rudnick Berlack Israels LLP; Latham & Watkins LLP Sector: HEALTH

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AGREEMENT AND PLAN OF MERGER

EXHIBIT 2.2

EXECUTION COPY

AGREEMENT AND PLAN OF MERGER

BY AND AMONG

HOLOGIC, INC.,

HYDROGEN ACQUISITION, INC.

AND

R2 TECHNOLOGY, INC.

DATED: APRIL 24, 2006

TABLE OF CONTENTS


RECITALS:		1

ARTICLE I. THE MERGER; CLOSING		2

1.1	THE MERGER	2
1.2	EFFECTIVE TIME	2
1.3	EFFECTS OF THE MERGER	2
1.4	CERTIFICATE OF INCORPORATION OF SURVIVING CORPORATION	3
1.5	BYLAWS OF SURVIVING CORPORATION	3
1.6	OFFICERS AND DIRECTORS OF SURVIVING CORPORATION	3
1.7	CONVERSION OF SECURITIES	3
1.8	ADJUSTED MERGER CONSIDERATION; ESCROWED MERGER CONSIDERATION; DISSENTING SHARES	5
1.9	SURRENDER OF CERTIFICATES	8
1.10	NO FRACTIONAL SHARES; MULTIPLE CERTIFICATES	11
1.11	ESCROW AGREEMENT	11
1.12	STOCK TRANSFER BOOKS	11
1.13	STOCKHOLDER REPRESENTATIVE	11
1.14	ANCILLARY AGREEMENTS	12
1.15	TERMINATION OF STOCKHOLDER AGREEMENTS	13

ARTICLE II. REPRESENTATIONS AND WARRANTIES CONCERNING THE COMPANY		13

2.1	ORGANIZATION AND GOOD STANDING	13
2.2	AUTHORITY; NO CONFLICT	14
2.3	CAPITALIZATION	15
2.4	BOOKS, RECORDS AND ACCOUNTS; INTERNAL CONTROLS	16
2.5	FINANCIAL STATEMENTS	17
2.6	NO UNDISCLOSED LIABILITIES	17
2.7	TAXES	18
2.8	ACCOUNTS RECEIVABLE	19
2.9	REORGANIZATION TREATMENT	20
2.10	TITLE TO PROPERTIES; ENCUMBRANCES	21
2.11	CONDITION OF ASSETS	22
2.12	COMPLIANCE WITH LAWS; GOVERNMENTAL AUTHORIZATIONS	22
2.13	LEGAL PROCEEDINGS	22
2.14	ABSENCE OF CERTAIN CHANGES AND EVENTS	23
2.15	CONTRACTS; NO DEFAULTS	24
2.16	INSURANCE	26
2.17	ENVIRONMENTAL MATTERS	27
2.18	EMPLOYEES	28
2.19	EMPLOYEE BENEFITS	28
2.20	LABOR RELATIONS	31
2.21	INTELLECTUAL PROPERTY	32
2.22	CERTAIN PAYMENTS	34
2.23	RELATIONSHIPS WITH RELATED PERSONS	35
2.24	BROKERS OR FINDERS	35
2.25	CUSTOMER RELATIONSHIPS	35
2.26	SUPPLIERS	35
2.27	INVENTORIES	35
2.28	PRODUCT WARRANTIES; PRODUCT LIABILITY	36
2.29	FDA AND REGULATORY MATTERS; CLINICAL TRIALS	36
2.30	FINANCIAL SERVICE RELATIONS; POWERS OF ATTORNEY	38


AGREEMENT AND PLAN OF MERGER		Page i


2.31	COMPANY ACTION	38
2.32	COMPANY STOCKHOLDER VOTE REQUIRED	38
2.33	OUTSTANDING INDEBTEDNESS FOR BORROWED MONEY	38
2.34	INFORMATION SUPPLIED BY THE COMPANY	39
2.35	DISCLOSURE	39

ARTICLE III. REPRESENTATIONS AND WARRANTIES OF PARENT AND MERGER SUB		39

3.1	ORGANIZATION AND GOOD STANDING	39
3.2	AUTHORITY; NO CONFLICT	40
3.3	CAPITALIZATION; MERGER SHARES	41
3.4	FILINGS WITH THE SEC	41
3.5	RIGHTS AGREEMENT	42
3.6	BROKERS OR FINDERS	42
3.7	TAXES	42
3.8	REORGANIZATION TREATMENT	43
3.9	PARENT STOCKHOLDER VOTE REQUIRED	44

ARTICLE IV. COVENANTS		44

4.1	NORMAL COURSE	44
4.2	CONDUCT OF BUSINESS	44
4.3	STOCKHOLDER APPROVAL	47
4.4	CERTAIN FILINGS	48
4.5	NOTIFICATION OF CERTAIN MATTERS	49
4.6	NO SOLICITATION	49
4.7	EMPLOYEE MATTERS	51
4.8	ACCESS TO INFORMATION; CONFIDENTIALITY	52
4.9	COMMERCIALLY REASONABLE EFFORTS; FURTHER ACTION	52
4.10	PROXY STATEMENT; PARENT STOCKHOLDER MEETING.	53
4.11	FINANCIAL INFORMATION AND ACCOUNTANTS CONSENTS	54
4.12	FAIRNESS HEARING, REGISTRATION OF SHARES	55
4.13	CAPITALIZATION CERTIFICATE	56
4.14	SECTION 280(G)	56
4.15	FOREIGN QUALIFICATION	57

ARTICLE V. ADDITIONAL COVENANTS OF THE PARENT		57

5.1	CERTAIN FILINGS	57
5.2	LISTING OF MERGER SHARES	57
5.3	INDEMNIFICATION AND INSURANCE	57

ARTICLE VI. CONDITIONS TO OBLIGATIONS OF PARENT AND MERGER SUB		58

6.1	REPRESENTATIONS AND WARRANTIES	58
6.2	PERFORMANCE OF COVENANTS	58
6.3	DISSENTING STOCKHOLDERS	59
6.4	COMPANY STOCKHOLDER APPROVAL	59
6.5	COMPANY MATERIAL ADVERSE EFFECT	59
6.6	UPDATED CERTIFICATE	59
6.7	PARENT STOCKHOLDER APPROVAL	59
6.8	NO GOVERNMENTAL OR OTHER PROCEEDING; ILLEGALITY	59
6.9	APPROVALS AND CONSENTS	59
6.10	NASDAQ LISTING	60
6.11	OPINION OF COUNSEL	60
6.12	FAIRNESS APPROVAL; EFFECTIVENESS OF REGISTRATION STATEMENT	60
6.13	OTHER DOCUMENTS	60

ARTICLE VII. CONDITIONS TO OBLIGATIONS OF THE COMPANY		60

7.1	REPRESENTATIONS AND WARRANTIES	60


AGREEMENT AND PLAN OF MERGER		Page ii


7.2	PERFORMANCE OF COVENANTS	61
7.3	PARENT STOCKHOLDER APPROVAL	61
7.4	PARENT CLOSING CERTIFICATE	61
7.5	COMPANY STOCKHOLDER APPROVAL	61
7.6	NASDAQ LISTING	61
7.7	NO GOVERNMENTAL OR OTHER PROCEEDING; ILLEGALITY	61
7.8	APPROVALS AND CONSENTS	62
7.9	OPINION OF COUNSEL	62
7.10	FAIRNESS APPROVAL; EFFECTIVENESS OF REGISTRATION STATEMENT	62

ARTICLE VIII. TAX MATTERS		62

8.1	TAX FREE MERGER	62