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EXHIBIT 10.2 AGREEMENT

Advertising or Marketing Agreement

EXHIBIT 10.2   AGREEMENT | Document Parties: OccuLogix, Inc. You are currently viewing:
This Advertising or Marketing Agreement involves

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Title: EXHIBIT 10.2 AGREEMENT
Date: 5/6/2005

EXHIBIT 10.2   AGREEMENT, Parties: occulogix  inc.
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                                                                    EXHIBIT 10.2

 

                                    AGREEMENT

 

      THIS AGREEMENT (the   "AGREEMENT")   made this 28th day of March,   2005 (the

"EFFECTIVE   DATE")   between   OccuLogix(R),   Inc.   ("OCCULOGIX"),   a   corporation

incorporated   under   the   laws   of   the   State   of   Delaware,   and   Rheogenx(TM)

Biosciences Corporation (the "PURCHASER"),   a corporation incorporated under the

laws of the State of Delaware.

 

      WHEREAS OccuLogix wishes to sell the Products (as hereinafter   defined) to

the Purchaser, and the Purchaser wishes to purchase the Products from OccuLogix,

under the terms provided herein.

 

      AND WHEREAS   OccuLogix   and the   Purchaser   also desire to develop a joint

marketing relationship to promote the use of the RHEO System and the Purchaser's

mobile    apheresis    business   and   to   provide   for   certain    other    business

arrangements.

 

      NOW THEREFORE,   in   consideration   of the mutual   covenants and agreements

herein   contained   and other good and   valuable   consideration   (the receipt and

sufficiency of which are hereby acknowledged), the parties agree as follows:

 

                                   ARTICLE 1

                                 INTERPRETATION

 

      1.1   DEFINITIONS.   In this   Agreement,   the following terms shall have the

meanings set forth below, unless the context requires otherwise:

 

      "ADVERSE   PATIENT   EVENT" means an   "Unanticipated   Adverse Device Effect"

that   is   reported   or is   reportable   to the FDA   under   the   Code   of   Federal

Regulations,   Part 21 CFR 812, or any   successor   regulation,   and any   "Adverse

Event" that is   reported or is   reportable   under the Medical   Device   Reporting

regulations as defined in the Code of Federal   Regulations,   Part 21 CFR 803, or

any successor   regulation,   in each case,   whether or not such event is actually

reported to the FDA.

 

      "AFFILIATE(S)" means, in respect of a Person (the "FIRST PERSON"), another

Person that,   directly or   indirectly:   (i) controls the First   Person,   (ii) is

controlled   by the First Person or (iii) is   controlled   by the same Person that

controls the First Person. In this definition, "control" means ownership of more

than 50% of another Person or the power to direct   decisions of another   Person,

including the power to direct   management and policies of another Person whether

by reason of ownership, contract or otherwise.

 

      "BUSINESS   DAY" means a day,   other than a Saturday,   Sunday or   statutory

holiday,   when   banks   are   generally   open   in the   State   of   Florida   for the

transaction of banking business.

 

      "CHANGE OF CONTROL" means the   occurrence of any of the following   events:

(i) any Person acquires or becomes the beneficial   owner of, or a combination of

Persons   acquires or becomes the   beneficial   owner of,   directly or indirectly,

more than 50% of the voting   securities of the   Purchaser,   whether   through the

acquisition of previously issued and outstanding voting securities, or of voting

 

 

<PAGE>

 

securities that have not been previously issued, or any combination   thereof, or

any other transaction having a similar effect;   (ii) any resolution is passed or

any action or proceeding is taken with respect to the   liquidation,   dissolution

or winding-up   of the   Purchaser;   (iii) the   Purchaser   merges with one or more

corporations   other than a   wholly-owned   subsidiary,   where a   majority   of the

Purchaser's   stockholders   immediately   prior to such   transaction do not hold a

majority of the issued and outstanding   securities of the combined company,   but

in any case this   Change   of   Control   provision   shall   not be   applied   to the

solicited   merger of the Purchaser with HemaCare   Corporation   regardless of the

outcome of the ownership of the   Purchaser's   securities   post-merger;   (iv) the

Purchaser sells, leases or otherwise disposes of all or substantially all of its

assets and undertaking, whether pursuant to one or more transactions; or (v) the

Purchaser   enters into any transaction or arrangement   which would have the same

or similar effect as the transactions described in (ii), (iv) or (v).

 

      "CONFIDENTIAL   INFORMATION"   of a party   means   any and all   material   and

information   of a   party   or   any   of   its   Affiliates   or   licensors   (in   this

definition, the "DISCLOSING PARTY") which has or may come into the possession or

knowledge of the other party or any of its Affiliates (in this   definition,   the

"RECIPIENT   PARTY")   in   connection   with or as a result of   entering   into this

Agreement,    including   information   concerning   the   Disclosing   Party's   past,

present,   and future customers,   suppliers,   finances,   affairs,   technology and

business.   For the purposes of this   definition,   "information"   and   "material"

includes   know-how,   data,   patents,    copyrights,    trade   secrets,   processes,

techniques,   programs,   designs,   designs   obtained by   reproducing   or reverse-

engineering product, formulae, marketing,   advertising,   financial,   commercial,

sales or   programming   materials,   written   materials,   compositions,   drawings,

proposals,   notes,   records,   diagrams,   computer   programs,   studies,   work   in

progress,   visual   demonstrations,   ideas,   concepts,   and other data,   in oral,

written, graphic,   electronic or any other form or medium whatsoever,   and shall

include all Intellectual   Property Rights and any information   identified by the

Disclosing Party as confidential, or which the Recipient Party should reasonably

know would constitute Confidential   Information.   Notwithstanding the foregoing,

"Confidential Information" does not include the following information:

 

      (i)    information   which is publicly   available   when it is received by or

            becomes known to the Recipient Party or which   subsequently   becomes

            publicly available through no fault of the Recipient Party (but such

            information will be considered   Confidential   Information until such

            time as it becomes publicly available);

 

      (ii)   information   which is already   known to the   Recipient   Party at the

            time of its   disclosure   to the   Recipient   Party by the   Disclosing

            Party and is not the subject of an   obligation   of confidence of any

            kind;

 

      (iii) information which is independently   developed by the Recipient Party

            without any use of or reference to the   Confidential   Information of

            the   Disclosing   Party   where such   independent   development   can be

            established   by   evidence   that   would be   acceptable   to a court of

            competent jurisdiction; and

 

      (iv)   information   which is received by the Recipient   Party in good faith

            from a third party whom the Recipient Party had no reason to believe

            was not   lawfully   in   possession   of such   information   free of any

            obligation of   confidence of any kind,   but only until the Recipient

            Party   subsequently   comes   to have   reason   to   believe   that   such

            information   was subject to an   obligation of confidence of any kind

            when originally received.

 

 

                                      -2-

<PAGE>

 

      "FDA" means the United States Food and Drug Administration.

 

      "FDA APPROVAL" means the approval of the FDA being sought by OccuLogix for

the RHEO   System   for use in   treatment   of   non-exudative   age-related   macular

degeneration (the specific labeling of which treatment will be determined by the

FDA).

 

      "FILTERS" means the filters   described in Schedule 1 attached hereto,   and

any new versions of such filters or   improvements   thereto,   or   replacement   or

substitution filters, that OccuLogix,   in its sole discretion,   may from time to

time sell in the regular course of its business.

 

      "GEOGRAPHIC   AREA" means any Canadian or U.S. city, town or   municipality,

and its surrounding   area to an extent of a 50-mile radius   thereabout,   that is

specified in the Geographic Areas Schedule, attached hereto as Schedule 2, as it

may be amended from time to time by the parties hereto.

 

      "INTELLECTUAL PROPERTY RIGHTS" means:

 

      (a)    any and all   proprietary   rights provided under (i) patent law, (ii)

            copyright law, (iii) trademark law, (iv) design patent or industrial

            design   law,   (v)   semi-conductor   chip or mask work law or (vi) any

            other statutory provision or common law principle applicable to this

            Agreement,   including trade secret law, which may provide a right in

            either    ideas,    formulae,    algorithms,     concepts,    inventions,

            documentation,   Confidential   Information or know-how generally,   or

            the expression or use of such ideas, formulae, algorithms, concepts,

            inventions or know-how; and

 

      (b)    any and all   applications,   registrations,   licenses,   sub-licenses,

            franchises, agreements, renewals or any other evidence of a right in

            any of the foregoing.

 

      "PATIENT   INFORMATION"   means   all   information,   data   and   test   results

collected by the   Purchaser   in   connection   with the use of the   Products   with

patients, provided that such information, data and test results will be provided

to   OccuLogix   in such   form so that   the   patients   will not be   identified   in

accordance   with   the   standard   of    de-identification    of   protected    health

information set forth in CFR ss. 164.514.

 

      "PERSON" means an individual, corporation,   partnership, limited liability

company, trust, business trust, association, joint stock company, joint venture,

pool, syndicate, sole proprietorship,   unincorporated organization, governmental

authority or any other form of entity.

 

      "PRODUCTS" means,   together, the Pump, Tubing Sets and the Filters and any

new   versions of such   products   or   improvements   thereto,   or   replacement   or

substituted products, that OccuLogix,   in its sole discretion,   may from time to

time sell in the regular course of its business.

 

 

                                      -3-

<PAGE>

 

      "PUMP" means the   OctoNova(R)   Apheresis   Machine   described in Schedule 1

attached hereto and any new versions of such product or improvement   thereto, or

replacement or substitution   products,   that OccuLogix,   in its sole discretion,

may from time to time sell in the regular course of its business.

 

      "RHEO   SYSTEM"   means   the   Products   used   to   perform   Rheopheresis   and

consisting of a Pump and a disposable   treatment set, containing the Filters and

Tubing Sets, through which the patient's blood circulates.

 

      "RHEO   THERAPY"   means   the   performance   of   Rheopheresis   using the RHEO

System.

 

      "SECTION   510   APPROVAL"   means   approval of the FDA   granted   pursuant to

section 510(k) of the U.S. Food, Drug and Cosmetic Act.

 

      "THIRD   PARTY" shall mean any Person other than   OccuLogix,   the Purchaser

and their respective Affiliates.

 

      "TUBING   SETS" means the   disposable   tubing sets forming part of the RHEO

System.

 

      1.2   EXTENDED   MEANINGS.   Unless the   context   requires   otherwise,   words

importing the singular   include the plural and vice versa,   and words   importing

gender   include all genders.   The terms   "including"   and   "include"   shall mean

"including without limitation" and "include without limitation," respectively.

 

      1.3 REFERENCES TO "OCCULOGIX" AND "PURCHASER". Unless the context requires

otherwise,   in this   Agreement,   references   to   "OCCULOGIX"   are   references to

OccuLogix, Inc. and all of its Affiliates, and references to the "PURCHASER" are

references to Rheogenx Biosciences Corporation and PhereSys Therapeutics and all

of their respective Affiliates.

 

      1.4 CURRENCY.   Unless otherwise stated,   all dollar amounts referred to in

this Agreement are in United States dollars.

 

      1.5 LEGAL COUNSEL.   The parties   acknowledge   that their   respective legal

counsel have reviewed and   participated   in settling the terms of this Agreement

and that any rule of   construction   to the effect   that any   ambiguity   is to be

resolved    against   the   drafting    party   shall   not   be    applicable    in   the

interpretation of this Agreement.

 

      1.6 REMEDIES   CUMULATIVE.   Unless otherwise   expressly stated herein,   all

rights and remedies of either party under this Agreement are in addition to such

party's other rights and remedies and are cumulative, not alternative.

 

      1.7 AGREEMENT AND SCHEDULE   AMENDMENT AND SUPPLEMENT.   Except as expressly

set out in this   Agreement,   this   Agreement,   including   each   Schedule to this

Agreement, may not be amended or supplemented except by mutual written agreement

of at least   one   authorized   representative   of each of the   parties.   Any such

agreement   will expressly   state that it is intended to amend or supplement,   as

the case may be, this Agreement.

 

 

                                       -4-

<PAGE>

 

      1.8 SCHEDULES.   This   Agreement   includes and   incorporates   the following

schedules:

 

            Schedule 1 - Product List and Prices

 

            Schedule 2 - Geographic Areas Schedule

 

                                   ARTICLE 2

                        PRODUCTS AND PATIENT INFORMATION

 

      2.1   PURCHASE.   Upon   submission   of a   purchase   order   by the   Purchaser

("ORDER")   and   acknowledgment   and   acceptance   of   such   Order   by   OccuLogix,

OccuLogix will sell, and the Purchaser will purchase, the Products at the prices

specified   in Schedule 1 attached   hereto,   as such prices may be adjusted   from

time to time pursuant to Section 2.7 hereof. Each such Order shall be in writing

in a form   reasonably   acceptable to OccuLogix and shall specify the quantity of

each of the Products ordered,   the place of delivery and the requested   delivery

date   therefor,   which   shall   not be less   than 60 days   after the date of such

Order.   Until such time as the FDA Approval is granted,   OccuLogix   will have no

obligation   to deliver any   Products   to the   Purchaser   at any   location in the

United   States.   In the event of a conflict   between the terms and conditions of

any Order and this   Agreement,   the terms and conditions of this Agreement shall

prevail, and any additional or different terms shall be of no force or effect.

 

      2.2 RIGHT TO REJECT ORDERS.   OccuLogix   shall have the right to reject any

order   placed   by the   Purchaser   if the   Purchaser   is in   breach of any of its

material obligations under this Agreement. The Purchaser's Order shall be deemed

accepted when it is acknowledged and accepted by OccuLogix in writing. Any Order

that OccuLogix fails to accept or reject within five business days of receipt of

such Order from   Purchaser   shall be deemed   accepted.   Subject to Section   2.3,

below,   the Purchaser may not cancel any order after it is accepted by OccuLogix

without the written consent of OccuLogix. 2.3 DELIVERY SCHEDULE. OccuLogix shall

make commercially   reasonable efforts to deliver the Products in accordance with

the delivery   schedules set forth in the accepted Orders.   However,   if anything

beyond the control of   OccuLogix   prevents   OccuLogix   from   completely   filling

Orders   accepted by OccuLogix   in   accordance   with this Section 2.3,   OccuLogix

shall immediately notify Purchaser of any such delay in writing and the expected

delivery   date(s) for the unshipped   portion of the Order.   The Purchaser   shall

have the right to cancel the unshipped   portion of any Order for which OccuLogix

indicates   an   expected   delivery   date of more than 45 days after the   original

delivery date requested by the Purchaser,   provided that the Purchaser   notifies

OccuLogix,   within five business days of receipt of notice of delayed   delivery,

of the Purchaser's intention to exercise of its right of cancellation under this

Section 2.3.

 

      2.4 DELIVERY.   All Products supplied under this Agreement shall be shipped

f.o.b. the place of manufacture to such location as designated by the Purchaser.

Title and risk of loss and damage to the   Products   purchased   by the   Purchaser

hereunder shall pass to the Purchaser upon receipt by delivery to the applicable

carrier.

 

      2.5   PACKAGING.   All   Products   supplied   under   this   Agreement   shall be

packaged   in such   manner   as   OccuLogix   reasonably   determines,   in all   cases

consistent with industry practice for the shipment of similar goods.

 

 

                                      -5-

<PAGE>

 

      2.6   INABILITY   TO SUPPLY.   OccuLogix   shall not be liable for   failure to

supply Products or for the late delivery of Products if (i) OccuLogix orders the

Products (or components   thereof) from its supplier(s) and such supplier(s) fail

to deliver such Products or   components   thereof) or (ii)   OccuLogix's   supplier

terminates   its   agreements   with   OccuLogix   for the supply of the Products (or

components thereof). In the event of the occurrence of (i) above, OccuLogix will

(i) use commercially   reasonable   efforts to notify the Purchaser as promptly as

practicable of the circumstances,   (ii) discuss with the Purchaser ways in which

to remedy the   circumstances   and (iii) use commercially   reasonably   efforts to

supply the ordered Products as promptly as practicable thereafter.

 

      2.7 MOST   FAVOURED   NATION.   OccuLogix   will not sell the   Products to the

Purchaser at a price that is less favourable than OccuLogix's   lowest list price

in effect at the time of   submission of the Order.   In the event that   OccuLogix

sells Products to another   customer at a price per unit   (including any rebates,

incentives,   offsets   or other   discounts)   that is less than the price per unit

payable by the Purchaser pursuant to this Agreement, OccuLogix shall provide the

Purchaser   with a credit for any excess   amount   charged to the   Purchaser   with

respect to any Products   which were shipped to the   Purchaser   after the date on

which   such   lower   price was   offered   to such   other   customer.   In   addition,

OccuLogix   will use its best   efforts to   expedite   processing   of all   accepted

orders from the Purchaser and shall make all commercially   reasonable efforts to

prioritize the processing,   shipment and delivery of the Purchaser's Orders. For

greater certainty, commercially reasonable efforts will not require OccuLogix to

fill any   Orders   submitted   by the   Purchaser   before   filling   any   orders   of

OccuLogix's   other customers which were submitted prior to the submission of the

Purchaser's   Orders,   but will require OccuLogix to fill any Orders submitted by

Purchaser   before filling any orders of OccuLogix's   other   customers which were

submitted after the submission of the Purchaser's Orders.

 

      2.8 PATIENT INFORMATION.   The Purchaser will provide OccuLogix with copies

of such Patient   Information   as OccuLogix may   reasonably   request from time to

time. The parties agree that the Patient Information shall be collected and held

in accordance with applicable privacy legislation.

 

      2.9 APPROVALS.   OccuLogix agrees to seek Section 510 Approval for the Pump

for non-Rheopheresis therapies, at its own cost and expense.

 

      2.10 NOTICE OF ADVERSE   EFFECTS.   OccuLogix   shall   provide   notice to the

Purchaser   promptly upon OccuLogix learning of any Adverse Patient Event that is

experienced by patients during use of any of the Products.

 

                                   ARTICLE 3

                       MARKETING AND OTHER RELATIONSHIPS

 

      3.1 JOINT MARKETING   CAMPAIGN.   OccuLogix and Purchaser shall cooperate in

connection with, and, as described below, devote such resources as are necessary

for, the preparation and implementation of a joint marketing campaign to promote

both the RHEO System and the Purchaser's mobile apheresis business, in all cases

subject to applicable   law,   including any necessary   approvals from the FDA and

any labeling   restrictions   or follow-on   requirements   imposed   thereby ("JOINT

MARKETING CAMPAIGN").

 

 

                                      -6-

<PAGE>

 

      The Joint Marketing Campaign shall include the following:

 

       (a)    Preparation   of written   materials and other media used in the joint

            marketing   to,   and/or    education   of,    healthcare    institutions,

            healthcare    facilities,     healthcare    providers     (collectively,

            "HEALTHCARE MARKET"), healthcare recipients and others;

 

      (b)    The   contribution   of suitable   resources,   including   personnel   as

            determined by the parties' representatives, as set forth below;

 

      (c)    Cost sharing for the   preparation   and   production   of marketing and

            educational materials;

 

      (d)    Co-sponsorship   of   seminars,   meetings,    presentations   and   other

            promotional and educational events;

 

      (e)    Co-promotion   to   the   Healthcare    Market,    including    healthcare

            providers'   facilities and practices,   and at healthcare   facilities

            and   institutions,   as may be   agreed   upon   by   OccuLogix   and   the

            Purchaser;

 

      (f)    Suitably   positioned   links on each   party's   websites   to the other

            party's   websites,   in each   case   with a brief   description   of the

            relationship established by this Agreement, with such language to be

            approved in advance by both parties;

 

      (g)    Coordination of any and all necessary joint   activities with respect

            to third party payors, insurance, billers and/or intermediaries; and

 

      (h)    All other   activities and materials as agreed upon by the parties in

            writing.

 

In   order    to    develop    and    implement    the    Joint    Marketing    Campaign,

representativesof   OccuLogix and the Purchaser shall meet within sixty (60) days

of the Effective   Date to determine the resources   necessary to proceed with the

development and implementation of the Joint Marketing   Campaign,   and to discuss

allocating such resources as they believe desirable to ensure a successful Joint

Marketing   Campaign.   Representatives   of   OccuLogix   and   the   Purchaser   shall

thereafter   meet regularly to analyze the   effectiveness   of the Joint Marketing

Campaign and revise such Joint   Marketing   Campaign   based on the then prevalent

market   conditions and, among other things,   changes in the Purchaser's   service

offering   and   markets   served.   Notwithstanding   any   other   provision   of this

Agreement,   neither   party shall use any   promotional   material   or   advertising

relating   in any   manner to the other   party,   or the   other   party's   business,

without such other   party's   written   consent   other than such   materi


 
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